#krebcycle

Krebs cycle # Steps of krebs cycle ....
Citric acid cycle _also known as tricarboxylic acid cycle TCA or Krebs cycle is a series of chemical reactions used by all aerobic organisms to generate energy through oxidation of acetyl_CoA derived from carbohydrates .fats,proteins into CO2 and chemical energy in the form of guanosine triphosphate GTP.
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How to remember Krebs cycle FOREVER ......
The name of this metabolic pathway is derived from citric acid ( a type of tricarboxylic acid) that is consumed and regenerated by this sequence of reactions to complete the cycle .
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Cycle consumes acetate ( in the form of acetl_CoA) and water, reduces NAD+ to NADH and produces carbon dioxide as a waste byproduct .The NADH generated by TCA cycle is fed into oxidative phosphorylation (Electron transport chain ETC)
In Eukaryotic cell......, TCA occurs in the matrix of mitochondria .
In Prokaryotes....,such as bacteria ,which lack mitochondria TCA reaction sequence is performed in cytosol with protein gradient for ATP production being across the cells surface , rather than the inner membrane of mitochondria .
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