Unveiling the Antibody Reactome: A New Frontier in Precision Immunology

Presented By: Joel Credle, PhD
Speaker Biography:
Joel Credle is one of the scientific co-founders of Infinity Bio and serves as the companies Director of Research and Developoment. Joel has 15+ years of experience in the development of novel hi-plex high-throughput assays with a focus on the accurate measurement of RNA and protein in patient-derived samples. Throughout his career, he has developed and employed novel invitro assays to measure RNA in fixed tissue (LISH), the detection of infectious DNA/RNA (cRASL), spatial transcriptomics (Lock’n’Roll) and MIPSA (molecular indexing of proteins by self-assembly), which can determine the entire antibody reactome from a single drop of blood. Joel has published over 20 peer-reviewed papers and is the inventor on numerous patents and patent applications.
As Director of R&D at Infinity Bio, Joel leads a “world-class” team of scientists whose focus is on the continuous development of new MIPSA library offerings, improvements to the assay itself and lastly, the production of high quality MIPSA reagent.
Joel holds a Ph.D., from Georgetown University, where he studied under Anita Sidhu, Ph.D., followed by a post-doctoral fellowship in the laboratory of H. Benjamin Larman, Ph.D., (Johns Hopkins University School of Medicine, Department of Pathology, co-founder & CSO at Infinity Bio).
Webinar: Unveiling the Antibody Reactome: A New Frontier in Precision Immunology
Webinar Abstract:
The human antibody repertoire, or reactome, is a vast and dynamic network of antibody-antigen interactions that plays a crucial role in health and disease. Understanding the complexity of this network is key to unlocking novel understanding of disease etiologies, new diagnostics, therapeutics, and personalized medicine approaches. In this webinar, Infinity Bio will showcase its cutting-edge technology for high-resolution antibody reactome profiling. We will delve into how this technology can provide unprecedented insights into the immune system's response to various diseases, including infectious diseases, autoimmune disorders, and allergies.
Key takeaways:
Discover Infinity Bio's next-generation antibody profiling assay, capable of capturing the full spectrum of antibody diversity with unmatched depth, precision and speed.
Explore real-world applications of this technology in
Biomarker discovery and patient stratification for health and disease research
Monoclonal antibody characterization: Target identification, cross-reactivity and sensitivity.
Learn how Infinity Bio's technology can transform our understanding of the immune system and pave the way for a new era of precision immunology.
Agenda
Intro of Joel Credle, PhD., Co-founder & Director of R&D
Infinity Bio company introduction
Significance and importance of antibody reactome profiling in human research
Our MIPSA technology, a next-gen antigen display tool
Automating MIPSA Assay: Confidence in the answers
Applications:
High Throughput Serology: The power of cohorts in translational research
Monoclonal Antibodies: Developing Therapeutic mAbs at scale
Q&A
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