Best Exercise in Oral submucous fibrosis (OSMF)|| 100% मुँह खुलेगा ||

Oral submucous fibrosis (OSMF) is an oral precancerous condition characterized by inflammation and progressive fibrosis of the submucosal tissues resulting in marked rigidity and trismus. OSMF still remains a dilemma to the clinicians due to elusive pathogenesis and less well-defined classification systems. Over the years, many classification systems have been documented in medical literature based on clinical, histopathological, or functional aspects. However, none of these classifications have achieved universal acceptance. Each classification has its own merits and demerits. An attempt is made to provide and update the knowledge of classification system of OSMF so that it can assist the clinicians, beneficial in researches and academics in categorizing this potentially malignant disease for early detection, prompt management, and reducing the mortality. Along with this, pathogenesis and management have also been discussed.
Keywords: Areca nut, blanching, collagen, fibrosis, oral submucous fibrosis
Oral submucous fibrosis (OSMF) precancerous condition and is chronic, resistant disease characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues. In 1966, Pindborg[1] defined OSMF as “an insidious chronic disease affecting any part of the oral cavity and sometimes pharynx. It is associated with juxta-epithelial inflammatory reaction followed by fibroelastic changes in the lamina propria layer, along with epithelial atrophy which leads to rigidity of the oral mucosa proceeding to trismus and difficulty in mouth opening.” Other terms used to describe this condition are juxta-epithelial fibrosis, idiopathic scleroderma of the mouth, idiopathic palatal fibrosis, submucous fibrosis of the palate and pillars, sclerosing stomatitis, and diffuse OSMF.[2]
It occurs at any age but most commonly seen in young and adults between 25 and 35 years (2nd-4th decade). Onset of this disease is insidious and is often 2-5 years of duration. It is commonly prevalent in Southeast Asia and Indian subcontinent.[3] The prevalence rate of OSMF in India is about 0.2%-0.5%. This increased prevalence is due to increased use and popularity of commercially prepared areca nut and tobacco product - gutkha, pan masala, flavored supari, etc.[4] The malignant transformation rate of OSMF was found to be 7.6%.
ETIOPATHOGENESIS
OSMF was first described by Schwartz in 1952, where it was classified as an idiopathic disorder by the term atrophia idiopathica (tropica) mucosae oris.[5] Since then, many hypotheses are being suggested that OSMF is multifactorial in origin with etiological factors are areca nut, capsaicin in chilies, micronutrient deficiencies of iron, zinc, and essential vitamins. Autoimmune etiological basis of disease with demonstration of various autoantibodies with a strong association with specific human leukocyte antigen (HLA) antigens has also been suggested.[6]
Areca nut (betel nut) chewing is one of the most common causes of OMSF which contains tannins (11%-12%) and alkaloids such as arecoline, arecaidine, guvacine, and guvacoline (0.15%-0.67%). Out of all arecoline is the main agent. Arecaidine is an active metabolite in fibroblast stimulation and proliferation, thereby inducing collagen synthesis. With the addition of slaked lime (Ca[OH] 2) to areca nut, it causes hydrolysis of arecoline to arecaidine making this agent available in the oral environment. Tannin present in areca nut reduces collagen degradation by inhibiting collagenases. OSMF is induced as a combined effect of tannin and arecoline by the mechanism of reducing degradation and increased production of collagen, respectively.[5]
Nutritional deficiencies
Deficiency of iron (anemia), Vitamin B complex, minerals, and malnutrition are promoting factors that disturbs the repair process of the inflamed oral mucosa, thus leads to deranged healing and resultant scarring and fibrosis. The resulting atrophic oral mucosa is more susceptible to the effects of chilies, betel nuts, and other irritants.[7]
Genetics and immunology
A genetic component is believed to be involvement in OSMF because there are cases reported in medical literature in people without any history of betel nut chewing or chili ingestion. Patients with OSMF have increased frequency of HLA-A10, HLA-B7, and HLA-DR3.
An immunologic phenomenon is thought to play a role in the etiopathogenesis of OSMF. The increase in CD4 cells and cells with HLA-DR in these diseased tissues shows activation of most lymphocytes and increased number of Langerhans cells. These immunocompetent cells and high of CD4:CD8 ratio in OSMF tissues show the activation of cellular immune response which results in deranged immunoregulation and an altered local tissue morphology. These changes may be due to direct stimulation from exogenous antigens such as areca alkaloids or due to changes in tissue antigenicity leading an autoimmune response.

[@joebernard1022]

One of the best video....even though you dont take tobacco or alcoholic product ,you are helping so many of us....god bless you..mam

[@alpeshbhatt8958]

Bahot hi cute doctor ho aap...aapki sari excecise start karni padegi filhal koi problem nahi hai but 2 Ungali nahi ja rahi hai tobacco 7 saal pahele chhod diya tha

[@pandeysdentalclinic]

Thanks for the complement 😊

[@rajubhaikittuofficial]

Very powerful, fantastic, mind blowing, extraordinary, wonderfull video madam🙏

[@pandeysdentalclinic]

Thanks 🙏

[@bajrang9291]

After 8th day of #wisdom tooth removal these exercises are helpful 🎉...thanks you!

[@pandeysdentalclinic]

Thanks 🙏

[@jyotisaroj1766]

Mem mera 1 year 4 month phle left side uper niche wisdom tooth surgery dwara remove hua tha uper last dato ke uper jo incision lga tha wha take ke jgh pe skin grey colour ho gya h aur masude ekttha ho gya h

[@bajrang9291]

@@jyotisaroj1766 aoko koi samsya hai to ek bar apne dentist ko dikhayie

[@shobhajames4176]

one of the best video with information👍

[@sanjayamallick5676]

Thanks for your valuable suggestions

[@pandeysdentalclinic]

Welcome 🤗

[@sprakash7130]

Doctor very helpful & positive advice's.Truly inspiring the way you present regarding treatments of osmf. I would like to see your more latest videos on this topic.Really felt a lot of relief after seeing your video.Pls advice more options so as to eradicate this menace.I was never aware in my life that such an disease exists.I want to lead a good normal life.pls offer more help thru your consultings.Good day.

[@jeetgupta2781]

Hello sir how are you now?

[@user-oj2jm5gs3i]

Hey ma'am... thanks to you for saving many people lives u're best doctor in the world....
I have small question for u....ye jo massage hain ye krne se osmf dur hota h or mouth skin tite bhi dur hoti h na ??

[@pandeysdentalclinic]

Exercise ke bad ye massage se muscles relax hoti hain..

[@rajwantimarkam9098]

Very nice 👌 interesting video 😍 ma'am

[@rupesh4173]

Mera stage 4 tha ye excercise bahut kaam ka hai

[@Lovestatus-qz1pf]

Apka khulne lga kya

[@rupesh4173]

​@@Lovestatus-qz1pfhaa

[@InduKumari-bf3um]

Very nice information ma'am 👌👌👌

[@pandeysdentalclinic]

Thanks 😊

[@jageshwarbais]

Thanks mam aapke batane ki tarika bhi achhchi hai mouth exercise

[@Rasmika126]

Aaj aapki exercise krnege kyunki moh nhi khul raha hai tnqq mem

[@aishadeka9989]

Very good information thank you ma'am

[@pandeysdentalclinic]

Most welcome 🙏

[@ahmeryameen4184]

Very good information Thank you.

[@pandeysdentalclinic]

My pleasure 🙏

[@balveerjat9622]

Nice

[@pandeysdentalclinic]

Thanks

[@king_khan1437]

Nice explanation thank you ma'am

[@pandeysdentalclinic]

Welcome 🙏

[@shaileshwagh7437]

Very good

[@pandeysdentalclinic]

Thanks 🙏

[@bob7966]

Ma'am,can it be because of cancer? I'm too scared.

[@umeshjoshi8182]

Wah wah... badhiya..

[@user-rm3ys6gs8h]

Best video madam thankyou

[@arogyam9973]

Mam mujhe treatment cahiye

[@dharambirsingh555]

Good Dr. Sahab

[@DineshKumar-kj6dt]

Very good information

[@rachnakumari1924]

Very nice information ma'am 👍👍

[@pandeysdentalclinic]

Thanks 😊

[@sambitdas100]

Help koro peeg 😟

[@solution24houre]

धन्यवाद दीदी

[@pandeysdentalclinic]

My pleasure 🙏

[@p781981k]

Very nice so good❤

[@FaisalMughalFaisalMughal-vw1ds]

Very good mame thanks 😊

[@arogyam9973]

Jo scarcathesch hue h galo me uske liye kuch cream btaye

[@pandeysdentalclinic]

Bina condition dekhe treatment nai hota..

[@k.kgupta6037]

Very nice

[@just_meh2160]

TURMIX & LYCOSTAR It helps.

[@pandeysdentalclinic]

Yes

[@parbinkumar3855]

Superb video

[@tanmayihegde]

Mam i have osmf hai since 1 yr.. Very burning sensation in mouth and only 1 finger i can insert.. I am affraid of going to doctor.. Plzz help me out mam plzzz.. Plzz suggest some good medicine.. And i have started excersise by seeing ur video.. Plzz suggest me some tablet mam plzz

[@pandeysdentalclinic]

Tab trinergic L daily one for 6months..

[@tanmayihegde]

@@pandeysdentalclinic thank u so much mam

[@pandeysdentalclinic]

@@tanmayihegde welcome 🙏

[@archie5656]

Bhai abhi thik hua kuch

[@AnkitPandey-kj4th]

Great Information 🙏🙏

[@pandeysdentalclinic]

Thanks 😊

[@stetusworld2409]

Mam please reply me
Mere mouth me 2finger jatte he abhi agar jabarjasti karu to 3 fingers jate he to 4 fingers ja sakte he kya ye wali exercise karke or kitne din tak karna hoga

[@pandeysdentalclinic]

Bhut time lagta hain but aapko 15days se hi result dikhne lagta hain…😊

[@sobhadwivedi4608]

Aise hi Aage badhate Raho

[@pandeysdentalclinic]

Thanks 🙏

[@archanapandey7591]

Very fantastic and knowledgefull video

[@pandeysdentalclinic]

Thanks 😊

[@user-wd4hd4cj4k]

Best video ma'am

[@shashankshukla6498]

very good information mam🙏

[@pandeysdentalclinic]

Thanks 🙏

[@Unknownboy295]

Garam pani se khul jayega kya ??❤

[@pandeysdentalclinic]

Garam pani namak se kulla karne se soft hoga gall aapka..

[@viveshkumarpandey3400]

Well.. information..👌👌

[@pandeysdentalclinic]

🙏

[@momins1856]

Hi Doctor can you please suggest me I'm in problem I quit all tabacco products inside my mouth Full surface is white like no circulation of blood How can I improve circulation please suggest me

[@maharsajjad2449]

Same problem

[@subalkumarsethy7770]

Great Tips Doctor Mam
Please provide the medicine name

[@pandeysdentalclinic]

Cap lycostar once a day for 3months

[@subalkumarsethy7770]

Thanks Mam

[@GhanshyamVadher]

@@pandeysdentalcliniclycostar new ye name Sahi hain?? Kyuki Google main yahi aaraha hain Please Mem reply thank you 😊

[@pandeysdentalclinic]

@@GhanshyamVadher ji

[@GhanshyamVadher]

@@pandeysdentalclinic thank you mem

[@mohammadparvezansari890]

thank you mam

[@Unknownboy295]

मेरा मुह नहीं खुल रहा 2 उंगली खुल रहा है ओर मेरा 2 महीने बाद bsf का❤ मेडिकल है क्या करु ?रोज गरम पानी से एक्सरसाइज भी करता हूं पर कोई फायदा नहीं हो रहा 😢

[@pandeysdentalclinic]

Etna jaldi fayda kaise hoga..esme time lagta hain..

[@mollysaji4021]

Thanks Mam

[@industrialagency7907]

Good Morning Madam 100% banth ha kiya dava or kiya karu 🙏🏻🙏🏻🙏🏻

[@pandeysdentalclinic]

Aap dentist ke pass proper treatment start kare…

[@SantoshKumar-fr6lb]

Kya Karun ki sahi ho jaaye sirf Van side hua hai Bus koi upay bataiye

[@lofikingomar6310]

No you are wrong the average minimum opening of mouth is 35mm-55mm it's equal to the width of 3 fingers not 4 fingers

[@gajendargajendar4498]

Thanks 👍

[@pandeysdentalclinic]

😊

[@mkmphysio9555]

Appreciate your impressive effort ❤

[@pandeysdentalclinic]

Thank you so much 😊

[@dikshanimsarkar5658]

Very nice 👌🏻👌🏻

[@Hamzakarodia7567]

Thanks

[@sanamsidiki]

Ma’am please reply mouth opening k liye konsi tablet use kare aur konsi gel use kare

[@pandeysdentalclinic]

Sari chije mouth condition par depend karti hain..

[@blackmamba8066]

Thanks mam aj se me use karunga ❤

[@pandeysdentalclinic]

Gud 🤗

[@sumittyagi2203]

Beautiful Dr... I want to come ur clinic.

[@pandeysdentalclinic]

Thanks..🙏

[@user-hf5wx7su7j]

Very informative video. Mam ye puchna tha k kia band daily exercise karne se loose ho k tootna shuru hojaengy?

[@pandeysdentalclinic]

Ji bilkul thik honge par time lagta hain thik hone main ..

[@sonalimhatre2035]

धंन्यवाद मॅडम

[@mayankupadhyay4921]

Very nice video.

[@pandeysdentalclinic]

Thanks 😊

[@veenachaddha1687]

Thank u

[@informative9825]

Mam suggest some medicines..am unable to eat anything..

[@pandeysdentalclinic]

Bina condition ke medicine nai diya ja sakta sorry…

[@anilsinghal3335]

Thanks doctor

[@pandeysdentalclinic]

😊🙏

[@ramuKUMAR-qx6gs]

Thank

[@vihepuyepthoka]

Mam, i can't put even 2 finger please suggest best medicine

[@pandeysdentalclinic]

Cap lycostar

[@king_khan1437]

Thank you

[@pandeysdentalclinic]

Welcome

[@vineetsingh9296]

madam koiyeh tablet lehna hai suggest any gel for ulcer

[@pandeysdentalclinic]

Anabel gel apply before meal..

[@nitinvachhani6300]

Very good detailed information

[@pandeysdentalclinic]

Thank you 🙏

[@AJAYKUMAR-nj6sw]

Very nice video mem

[@pandeysdentalclinic]

Thanks 🙏

[@skintiyz4503]

Mem mere gal ke do no side white peaches ek sal se hai thik nahi hora 😢😢😢😢 khan a khane mai bohot taklif hota hai 😢😢😢😢😢😢😢

[@HeenaKhan-rs3ru]

Mam mera mouth opening 2.2 hai to vo thik hoga ki nhi or exercise karne se bahut jyada darad hota hai Dr. Ko dikhi hu turmix dawai diye hai dr kya vo dawai acha hai

[@pandeysdentalclinic]

Ya medicine sahi hain,aap exercise,diet,medicine sab lete rahiye ar passions rakhiye aaram hoga par tension nai lena hain,time lagta hain esme…😊

[@swapnil6775]

Mam mere papa ko oreal cancer tha abhi Rediation chemo ho gaye hai rediation Band hoke abhi 15 Days huye hai unaka muh kuch Bhi nahi khul raha matlab Dat ke upar Dat Aa gaye he o exercise karte hai But bohot Dard hota hai O abhi 5 month se liquid diet par hi hai please kuch bataye please 🙏

[@pandeysdentalclinic]

Healing main time lagta hain…thoda patience rakhiye..exercise bas utna hi karway jisme dard na ho 🙏

[@swapnil6775]

@@pandeysdentalclinic ok mam very very thanks 🙏

[@KhanSalman-hg3dz]

Medicine kya hai

[@parmjitsingh4097]

Mam apka thanx mera wisdom thoot surgry se munh open nahi ho Raha tha apki exercise se abhi 15 stic ja Rahi hai but mam left side PE Kan ke pass dard hota hai or niche wala jabda thoda sa teda kulta hai khane ke samey bi dard hai 25 days ho geya abi streching bi nahi kholi please next treatment pl reply mam❤❤

[@pandeysdentalclinic]

Kulla kariyega garam pani namak se aur khan ke pass jaha dard hain oil se massage kariyega..

[@parmjitsingh4097]

Thanks ji

[@dhirajtiwari4961]

Mam mera muh 2 finger khulta hai...mai tobacco consumption 3-4 yrs kar rha hu...maine dentist dikhaya unhone bola osmf grade 2 hai mera...Mai Sm fibro aur eveon ye medicines use kr rha hu...unhone ice cream stick wala exercise bola hai...but prpb hai pehele 9 stick jata tha ab 11 stick chala jata hai...but 12 th stick bilkul bhi nhi jaa rha hai...mai depression me chala gyu mai thik ho pyukga ki nahi...normal life lead kar paunga ki nahi yesb thought ate hai...

[@pandeysdentalclinic]

Aapko hmesa better sochna chahiye,bhut log aapse bhi kharab condition main hain..jo hoga achcha hoga.. Be positive..😊🙏

[@Gamelife148]

Medam aap ye bhi boliye ki jyada balloon 🎈 fulane se jabda bhi full jata hei aur sujan AA jata he limited balloon fulana hei

[@pandeysdentalclinic]

Haan bilkul 😊👍

[@Nothereforthechase]

Doctor I have oral fibrosis stage 2. I have one small red spot where blister always comes out. Blister comes and goes alwyas. What to do ?

[@pandeysdentalclinic]

You started oil pulling with saseme oil..

[@Nothereforthechase]

Doctor I will try. Thank you so much ❤

[@Nothereforthechase]

Btw is Ulcer common in OSMF ? I'm scared Doctor

[@Nothereforthechase]

My ulcer always reappears in same spot

[@pandeysdentalclinic]

@@Nothereforthechase watch this
ua-cam.com/video/YQvKrH00ips/v-deo.htmlsi=Ky0sifgQGHlNgY0E

[@sinha.jk12]

mam mera bs 2 finger muh ke andar jata hai gutkha khate huye mujhe 2 sal ho gye mam aaj se mai ise khana band kr eha hu muh me jalan bhi bhot hota hai

[@pandeysdentalclinic]

ua-cam.com/video/YQvKrH00ips/v-deo.htmlsi=SgJ_Pe-ZTqoX7hP-

[@NomanAli-su1zg]

Thank you so much butt I like u Dr jyoti ji ❤❤

[@monikajain2357]

Pregnancy may mouth opening exercise kr saktay h kya mam? Or teeth may cavity h .usko bhi nikal saktay h kya mam.osmf h .

[@pandeysdentalclinic]

ua-cam.com/video/y9xY9e0PhpU/v-deo.htmlsi=KOXt0tWqVNwCISUE
Exercise kar sakte hain mouth open ka but baki treatment video main batay hain..

[@Beautywithnisha2M]

Kya yeh wisdom teeth ke baad mouth opening ke liye kr skte h

[@pandeysdentalclinic]

Sirf muh ko fulane wala exercise kare aap

[@AkashKharadkar]

Clinic address ?

[@pandeysdentalclinic]

Pandey’s dental clinic..hospital road..Wadrafnagar Chhattisgarh

[@rekhatanwar430]

Thank you so much 🙏

[@anuppanday6092]

Knowledge full video

[@pandeysdentalclinic]

😊

[@KuldeepKumar-ep9kn]

Mam mere muh me ak ungli hi jati thik hoga ki nhi gutka chod diye h please bataye 🙏

[@pandeysdentalclinic]

Thik ho jayega bs medicine le,exercise kare aur achcha khana khay..
ua-cam.com/video/UJ8CvMId4ug/v-deo.htmlsi=I1GBs1u2qSd0r8iT

[@user-mj7yr8nt3j]

Thum finger wala bahut acha laga❤

[@pandeysdentalclinic]

😊👍

[@gopalchakraborty9929]

Mam aapka advice bahut hi aacha laga.
Koi medicine bhi hai to kripiya bataiye ga

[@pandeysdentalclinic]

Bhut sare Medicine hain per Patient ke according medicine khana padta hain..sab Medicine sabke liye nai hota..😊

[@UMPking575]

Ok. Nice. 🥰🥰

[@handryalvos2692]

Mouth mein white pacthge hai toh Konsa doctor ko dikhaye mam

[@pandeysdentalclinic]

Dentist ko dikhaiye…

[@aajadkhan3638]

Mem konsa medicine lena hoga btaiye please reply

[@pandeysdentalclinic]

Bina condition detection ke medicine nai diya jata.Hope you understand

[@DrRaj-ok7hf]

Medicene kya batayn taki mein apne pateints ko bata paun?? Please

[@pandeysdentalclinic]

Koi bhi antioxidants ,uski cases ke according od aur bid de with circumin for 1year on or off karke…

[@DrRaj-ok7hf]

antibiotics deni chiye ya nhi

[@pandeysdentalclinic]

@@DrRaj-ok7hf condition ke according dena padta hain taki koi secondary infection na ho..

[@laljeeyadav4209]

Mam aap ka clinic kha par h plz give me a point ment for medicine

[@pandeysdentalclinic]

Pandey’s dental clinic,hospital road,Wadrafnagar Chhattisgarh

[@amanpratap6909]

Can u pls tell me any antioxidant

[@pandeysdentalclinic]

Tab lycostar

[@amanpratap6909]

@@pandeysdentalclinic okk mam tq so much

[@mohammedkaleemkaleem8634]

Mam mere muh me 3 ungliyan jaati thi mai jabran zor se 4 finger dala .. 4 finger to muh me chale gaye .. Mam ab mere skin(gaal) me dard ho raha hai dono side aur mu ke joint me bhi dard ho raha hai aur sujan bhi aaye hai ... Mam ye koi cancer to nhi hai na mam pls aap reply kijiye

[@pandeysdentalclinic]

Nai cancer nai hain…muscles stretching jyada ho gaya hain esliye dard ho raha hain..aap doctor se mil le sahi ho jayenge..

[@narendrasharma9072]

Kya dentist ke sath chiropractor se treatment le sakte h????

[@pandeysdentalclinic]

Yes no problem..😊👍

[@abdullahbangash1960]

My OSMF is advanced stage and can't insert 1 finger. Please advise tablet and jel. Respect from Pakistan

[@pandeysdentalclinic]

In this case only surgery is workable…

[@ALLnOneVivek]

Aap tambaku chhodo ....fir khana kaiae khate ho aap ...take care

[@amanpratap6909]

Nice mam

[@ilyasshaikh0989]

Mem meri 2 finger munh khul rha hai ar khana bhi tezzz lagta hai kya phle jaisa recovery hoga mem ??

[@pandeysdentalclinic]

ua-cam.com/video/nlrtBG0EwFY/v-deo.htmlsi=csqRQ6Kho7gmQFfp

[@EditorAli23]

mam mera last 6 months se ye prblm hai but ab chhod dunga main bht prblm hon jati hai

[@pandeysdentalclinic]

Great 👍

[@ALLnOneVivek]

Mam ye balloon ko fulane wali exericise se mere dono galo par kan ke neeche soiling aa gai hai.... Meri teen ungali muh me jati hai koi ghav nahi hai kewal pinkish white patches hai ...

[@pandeysdentalclinic]

Jyada exercise mat kijiye warna swelling hoga,suruwat main bhut thoda se suru karna hota hain…

[@AmarjeetKumar-sm7xr]

Mam mai bahat paresan hu bahat Sare doctor se dikhwa chuka hu but abhi tak thik nahi hua abhi bhi 2 ungli sahi se anda nahi ja pa raha hai mai kuch medicine bata do please mam meri help kijiye mai bihar ke sitamarhi jila se hu kafi dur hai aapka clinic mam esliye mai ane me asamarth hu mam please kuch dawa bata dijiye

[@pandeysdentalclinic]

Ji,aapko mouth opening exercises karte rahna hain aur sath main tab trinergic-L daily ek khane ke bad lena hain..i hope aapko 2month main improvement jarur milega..

[@AmarjeetKumar-sm7xr]

@@pandeysdentalclinic thank you so much mam

[@Devpatelll]

Ma'am mai gutka kv v nhi khata fir v 2 fingers hi jati h muh me
Plz btaye aisa Q hua ???
Muje koe dikkat feel nhi hoti.
Kya mujhe v treatment krani pdegi??

[@pandeysdentalclinic]

Condition dekhna hoga muh ka..aap red chillies jyada lete honge,yaa phir aapka muscles mouth ka jyada strech nai karta hoga..problem nai hain toh,no worry..