Treatment of Pyoderma gangrenosum

Pyoderma gangrenosum is an uncommon inflammatory and ulcerative skin disorder characterized histopathologically by the accumulation of neutrophils in the skin.
The most common presentation of Pyoderma gangrenosum is the rapid development of one or more painful, purulent ulcer with undermined borders on sites of normal or traumatized skin.
This video describes treatment options available for management of Pyoderma gangrenosum.
The treatment options for management of Pyoderma gangrenosum can be divided in four groups based on severity of the disease. These four categories are:
• First-line therapy
o Wound management
local care
surgical treatment
o For limited disease
Local corticosteroids: clobetasol propionate; triamcinolone.
Local calcineurin inhibitors: Topical tacrolimus
o For more extensive or rapidly progressing disease: Systemic glucocorticoids: prednisone, methylprednisolone; and Systemic cyclosporine
• Second-line and adjunctive therapies
Infliximab
Other biologic TNF-alpha inhibitors: Adalimumab, etanercept
Conventional immunosuppressants: mycophenolate mofetil, methotrexate, and azathioprine
Dapsone
Minocycline
• Treatment of refractory disease
Intravenous immune globulin
Alkylating agent: cyclophosphamide and chlorambucil
• Other therapies:
Thank you for watching this Video.
Please subscribe, share and hit the bell icon for more such videos.
Please visit my website: www.medicalinfo4u.com/
Check out my other videos:
Behçet’s Disease / Behçet’s Syndrome: • Behçet’s disease / beh...
Rheumatoid arthritis • Rheumatoid arthritis (...
Ankylosing spondylitis • Ankylosing spondylitis...
Osteoarthritis / degenerative arthritis: risk factors, clinical feature, diagnosis and treatment: • Osteoarthritis / degen...
crohn's disease/ regional enteritis for medical students • IBD Crohn's disease (C...
Hidradenitis suppuritive • Hidradenitis suppuriti...
Sjogren syndrome: • Sjogren syndrome and s...
Anterior uveitis, Posterior uveitis and Panuveitis: Etiology, Symptoms, Diagnosis and Treatment: • Anterior uveitis, post...
Side effects of steroids: • Side effects of steroids
Adalimumab (Humira/ Amgevita/ Imraldi/ Hyrimoz/ Hulio) -A magical drug for autoimmune diseases: • Adalimumab (humira a I...
#Pyodermagangrenosum
#Pyodermagangrenosumtreatment

[@maggieg.7744]

A Simple an to the point video on PG.

[@kimberbaker8649]

*******if anyone in the UK suffers from this condition and would like to take part in our show to raise awareness and see an award winning dermatologist Dr Emma Craythorne, please contact casting@**thebadskinclinic.co.uk** for more information*********

[@xenyane2231]

hello my brother is having very serious problems due to this disease. Do you know any treatment method, doctor or medicine? we live in turkey.

[@lisadolan689]

If I hear this digi voice again 😖

[@timothysheehan]

PG IS HORRIBLE,I SUFFER FROM PG FOR 4 YEARS

[@delrayharris6583]

What did you use to cure it

[@suzetterobinson63]

I'm taking a drug called ENTYVIO. It's taken Intravenously. I haven't have any outbreaks for awhile now.

[@xenyane2231]

hello my brother is having very serious problems due to this disease. Do you know any treatment method, doctor or medicine? we live in turkey.