Pharmacology of Centrally Acting Muscle Relaxants (Spasmolytics) by Dr.Shikha Parmar

Neuromuscular blocking agents are among the most commonly used drugs during general anaesthesia. They compete with acetylcholine and interfere with the transmission of nerve impulses resulting in skeletal muscle relaxation. Based on their mechanism of action, neuromuscular blocking agents are classified as either depolarizing or nondepolarizing. Succinylcholine is a short-acting depolarizing agent. Commonly used nondepolarizing agents are curare (long-acting), pancuronium (long-acting), atracurium (intermediate-acting), and vecuronium (intermediate-acting). Neuromuscular blocking agents are used clinically to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery.
Classification- Non-depolarizing blocking agents: These agents constitute the majority of the clinically relevant neuromuscular blockers.
Depolarizing blocking agents: These agents act by depolarizing the sarcolemma of the skeletal muscle fibre. This persistent depolarization makes the muscle fibre resistant to further stimulation by ACh.

[@gsrivani2440]

Excellent lecture
Well explained
Well understood mam

[@karnatinitheeshkumarreddy4016]

Well explained
Easy to understand
Thanks mam

[@jammuuniversity1451]

Excellent

[@user-ph2me2ed4c]

Goooooood 👍👍👍👍

[@user-ot2ri1uu8q]

Excellent.
Thank you

[@idapearline7995]

Well explained 👏

[@-spidey-7962]

Thank u so much mam..it helpd a lot..hope u make vdos like this more

[@dr.prasadpatil8254]

Thank u so much ...really helpful😃

[@radhakrishnanravichandran534]

Awesome explanation mam...tq mam

[@muhammadzaidbepari4322]

Short
With quality
Loved it

[@rukiyabashirshah6003]

Thank you so much mam,,,,it helped me alot literally a lot bless up mam❤❤❤your voice 🤩🤩🤩🤩😍😍😍😍

[@nicolefourie8841]

Great video!!

[@DrShikhaParmarClasses]

Thanks for the visit

[@tanyaievtushenko723]

Good job ,easy to understand. Thanks

[@DrShikhaParmarClasses]

Glad you liked it :)

[@smithaputhumana4448]

Very interesting class mam. Thank you.

[@DrShikhaParmarClasses]

Glad you liked it

[@manacy_vijith2182]

Super class mam

[@DrShikhaParmarClasses]

Thanks for watching and liking the video 🙂

[@yadavrinki599]

Mem kya aap coaching pdati he pharmacology ki

[@NainikamohammedFathima-hu9qe]

Thank you

[@DrShikhaParmarClasses]

Welcome!

[@vedaguttedar9461]

Mam give mechanism of action in theory type notes

[@ANILYADAV-jm4du]

Excuse me some basic information tell in hindi language
For understood

[@24kokilae51]

Excellent explanation mam.language pronounciation is clear but one dould mam .this lucture is sufficient or not for gpat preparation?

[@DrShikhaParmarClasses]

For GPAT, question practicing is the key

[@vickygarg9973]

Excellent work plz use some Hindi word to understand more

[@94.snehallatke10]

This notes are from which book

[@DrShikhaParmarClasses]

Please consult Essentials in Medical Pharmacology by KD Tripathi

[@94.snehallatke10]

@@DrShikhaParmarClasses which edition mam

[@DrShikhaParmarClasses]

@@94.snehallatke10 Seventh Edition or latest edition

[@94.snehallatke10]

@@DrShikhaParmarClasses thank you mam

[@ANILYADAV-jm4du]

Explanation is excellent but improve language not all but some basic things spell in hindi language for better understanding of students

[@sheethalelsajohn8017]

Not only hindi students are there listening to lecture videos🤷‍♀️

[@sheethalelsajohn8017]

What she is doing is an excellent job🤷‍♀️