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Kinexum Services LLC
United States
Приєднався 6 лип 2018
Kinexum supports the translational of scientific discoveries into healthcare products. We provide strategic and operational guidance and execution on regulatory, clinical, CMC, and related development challenges throughout the product development process and into commercialization. Our expertise is in diabetes, obesity, metabolic, cardiovascular, gastrointestinal, oncology, immunology, neurology, and more.
Відео
Digital Therapeutics (DTx) Webinar: A Powerful New Era in Healthcare
Переглядів 889Рік тому
Digital Therapeutics (DTx) is an exploding area. Join veteran Pharma thought leader Ed Saltzman, Head of Biotech Strategy at Lumanity, as he moderates a panel of DTx leaders, including Hogan Lovells digital health partner Jodi Scott, Eddie Martucci, CEO of Akili, which received the first FDA CDRH approval of a video game as a DTx, for ADHD, Nadav Shimoni, Head of Digital Health Sector, of Arkin...
Wow! or Yeow?! FDA Outlook for 2023 and Beyond
Переглядів 163Рік тому
The annual Kinexum Wow! or Yeow?! webinar was first held on Inauguration Day, January 20, 2017, to discuss whether the outlook for drug development in the coming year might be amazing (Wow!) or unexpectedly painful (Yeow?!). The 6th edition, held on January 20, 2023, now jointly hosted by Kinexum, Hogan Lovells and Hyman, Phelps & McNamara, features an all-star panel to review FDA developments ...
Wow Or Yeow?! FDA Outlook for 2022 and Beyond
Переглядів 4322 роки тому
The annual Wow! or Yeow?! to discuss whether the outlook for drug development in the coming year might be amazing (Wow!) or unexpectedly painful (Yeow?!). An all-star panel reviews FDA developments from the past year and looks ahead to the next. The panel will survey the entire FDA landscape-ranging from devices, digital technology, and vaccines to nutritional products. With FDA in the news eve...
Interview with Dr. Jay Skyler
Переглядів 2773 роки тому
A Kinexum webinar to learn more about Dr. Jay Skyler's career from his start through to his future. Alexander "Zan" Fleming, MD, Executive Chairman and Founder of Kinexum Services, interviews Jay Skyler, MD, Professor of Medicine, Pediatrics, and Psychology in the Division of Endocrinology, Diabetes, and Metabolism at the University of Miami. Jay Skyler, MD, MACP Dr. Jay Skyler is currently Pro...
Why and How Can Exercise Slow the Aging Process?
Переглядів 17 тис.3 роки тому
A Kitalys Institute webinar on why and how exercise can slow the aging process, featuring Drs. Daniel Lieberman (Harvard), Thomas Rando (Stanford), and Joan Mannick (Life Biosciences). Throughout history, exercise has been touted as a key to good health. Emerging research suggests that in addition to its overall health benefits, exercise also confers a degree of geroprotection, shielding practi...
Wow or Yeow?! FDA Outlook for 2021 and Beyond
Переглядів 2363 роки тому
2020 has been unprecedented and tumultuous due to simultaneous challenges of a once-in-a-century global pandemic, the resulting socio-economic fallout, and political polarization regarding policy responses to the pandemic, civil rights protests and presidential elections. The FDA has been pressured and challenged and responded with varying degrees of success and now faces an incoming administra...
Mitochondria, Aging, and Health
Переглядів 41 тис.3 роки тому
Mitochondria are commonly referred to as the powerhouses of cells because they create the energy necessary for cell function; however, these organelles do much more than that within our bodies. At Targeting Metabesity 2020 (www.metabesity2020.com) this past October, an expert panel led by mitochondrial genetics pioneer Dr. Doug Wallace discussed the key role of mitochondria in aging and health....
Role of Biological Clocks and Other Biomarkers of Aging in Regulatory Development
Переглядів 2,2 тис.4 роки тому
A Kinexum webinar on the role of biological clocks and other biomarkers of aging in regulatory development, featuring Drs. Steve Horvath (UCLA), Morgan Levine (Yale and Elysium Health), Robert Temple (FDA), Polina Mamoshina (Deep Longevity), and Luigi Ferrucci (National Institute on Aging).
Future of Type 1 Diabetes
Переглядів 5 тис.4 роки тому
A Kinexum webinar on the future of type 1 diabetes: where are we and where are we going? featuring Drs. Jay Skyler (University of Miami), Bruce Buckingham (Stanford University), G. Alexander Fleming (Kinexum), Matthias Hebrok (UCSF), and Chantal Mathieu (KU Leuven).
BARDA, Medical Countermeasures, and COVID-19
Переглядів 2184 роки тому
A Kinexum webinar on resources for public health defense: BARDA, medical countermeasures, and COVID-19, featuring Dean Calcagni, MD, Former Program Manager for USAMRDC; Conrad Clyburn, Former Director of Medical Programs for TATRC; Carol Linden, PhD, Former Principal Deputy Director of BARDA; and Steven Grossman, JD, Former Deputy Assistant Secretary for Health.
505b2 NDAs in the Era of COVID-19 and Beyond
Переглядів 744 роки тому
A Kinexum webinar on 505b2 NDAs in the era of COVID-19 and beyond, featuring Edward Allera, Co-chair of Buchanan Ingersoll & Rooney’s FDA & Biotechnology group; and Barbara Binzak Blumenfeld, PhD, Shareholder in Buchanan Ingersoll & Rooney’s FDA & Biotechnology group.
Coronavirus Meets Metabesity: Pandemics and Age-Related Diseases
Переглядів 4044 роки тому
A Kienxum webinar on the nexus between pandemics (i.e., coronavirus) and age-related diseases (i.e., metabesity). Moderated by Adriane Berg, JD, Host of Generation Bold Radio with panelists Joan Mannick, MD, CMO of resTORbio; Nir Barzilai, MD, Albert Einstein College of Medicine; Lawrence Steinman, MD, Stanford University; Cynthia Stuen, PhD, Chair of the NGO Committee on Ageing/NY; and Kathryn...
Wow Or Yeow?! FDA Outlook for 2020 and Beyond
Переглядів 654 роки тому
A Kinexum-Hogan Lovells webinar on the changes and news at FDA in 2020... Wow or Yeow!? Featuring David Fox, JD, Partner at Hogan Lovells; Steven Grossman, JD, President of HPS Group, Formerly Deputy Assistant Secretary for Health, Regulatory and Policy Consultant; Frank Sasinowski, Director of Hyman, Phelps, & McNamara; Alexander Fleming, MD, Founder and Executive Chairman of Kinexum; and Thom...
Herbal Medicine, Dietary Supplements, or Botanical Drugs?
Переглядів 8215 років тому
A Kinexum webinar on Tea, Dragon’s Blood, Cannabis, and Ginseng: Herbal Medicine, Dietary Supplements, or Botanical Drugs? featuring Jinhui Dou, PhD, Kinexum pharmacology and pharmacognosy senior consultant.
Metabesity 2019: Leveraging membership to expand metabesity movement
Переглядів 435 років тому
Metabesity 2019: Leveraging membership to expand metabesity movement
Metabesity 2019: Foundations, Patients and Government
Переглядів 415 років тому
Metabesity 2019: Foundations, Patients and Government
Metabesity 2019: How to fund longevity biotech
Переглядів 955 років тому
Metabesity 2019: How to fund longevity biotech
Metabesity 2019: Longevity industry investing
Переглядів 1025 років тому
Metabesity 2019: Longevity industry investing
Metabesity 2019: Metabolic deficit in Alzheimer’s disease
Переглядів 2205 років тому
Metabesity 2019: Metabolic deficit in Alzheimer’s disease
Metabesity 2019: Age-related Diseases
Переглядів 1165 років тому
Metabesity 2019: Age-related Diseases
Metabesity 2019: Overlap of metabolic diseases and early aging
Переглядів 585 років тому
Metabesity 2019: Overlap of metabolic diseases and early aging
Metabesity 2019: Established Companies
Переглядів 705 років тому
Metabesity 2019: Established Companies
Metabesity 2019: Aging as an opportunity to nurture vitality
Переглядів 1775 років тому
Metabesity 2019: Aging as an opportunity to nurture vitality
Metabesity 2019: Digital health improving cardiometabolic health
Переглядів 425 років тому
Metabesity 2019: Digital health improving cardiometabolic health
Metabesity 2019: Data and Advanced Analytics
Переглядів 1185 років тому
Metabesity 2019: Data and Advanced Analytics
Metabesity 2019: Artificial intelligence in preclinical discovery and clinical development
Переглядів 565 років тому
Metabesity 2019: Artificial intelligence in preclinical discovery and clinical development
So, hunter gatherers 1/ate all natural 2/fasted 3/exercised 4/low SF and still die around 70 .. that’s depressing. Add 10 years for modern medicine and nothing has changed
Why you all crying .no need .God create Man without mitochondrial his wife eat frute enter mitochondria in human body..so that kill one day because that kill your cell everyday by this ..read bible all day a ray passing over your body it control mitochondria.and drink wine and bread change your body by faith .
I disbelieve in evolution you propose to do what about it? Toss labels at me conjured by psychiatry, treat me as a witch!
😂Type 2 diabetes IS NOT CAUSED BY A HIGH FAT DIET but by a HIGH CARBOHYDRATE diet. Not sure why these “doctors” are so misinformed on “science”. 😮
I first met Dr.Skyler in 1987 he was my diabetologist. A great individual. David Bluhm
www.google.com/search?q=emf+interfere+cellular+function&rlz=1C1CHBF_enUS1048US1048&oq=emf+interfere+cellular+function&gs_lcrp=EgZjaHJvbWUyBggAEEUYOTIHCAEQIRigATIHCAIQIRirAtIBCjQxOTA1ajBqMTWoAgCwAgA&sourceid=chrome&ie=UTF-8
What ages/dies faster … mitochondria or other cells. ? Basically … what kills you … MC or non MC cells ?
very educational, keep on doing the good work.
High fat? High carbs!
You are clueless why we have mitochondria
Does anyone know what "ATP turnover rate" (27:10) means?
Mean rate consumed changing into original form giving energy . This comment from my physiology learning in medical school before listening to lecture. I see comments before listening to any lecture. I might change my reply after listening. ATP is like money currency of energy.
From the lecture 65-200 kilograms of ATP produced every day .Amazing data we did not know studying in best medical school.
salubrious. Lubrication with salty spit.
Keep on rockin'! This channel needs to look into smzeus!
Wow! Anxiously awaiting AI assisted Tx especially where it concerns identifying A-Fib in difficult cases.where diagnosis is difficult. Also of major concern is the power of our milk, egg and meat industries in dictating public nutritional guidelines plus the FDA's allowance of various names for sugar in the labeling content process. How regulations for highly processed foods perpetuates low nutrition for Americans by facilitating profit over health and well-being..
“Nothing in biology makes sense … “ except by intelligent design. Evolution is a theoretical lie.
Thank you. Yes resistances training works. At 75 year- I feel better than I did at 30. I don't have any pain in my body at all. I learned to swim at 70. I'm in the gym 3-5 times a week. I own 3 bikes. I very, very much enjoy biking. I'm grateful for my active life. I thank God!
Disappointed the speaker prior to Francesca blamed metabolic syndrome on only high fat diets as that dogma does not comport with reputable science.
Seriously!?? Does it get any more pale than this!??? The academia keeps marching backwards
You lost me at "we joined mice together so they shared the same circulatory system then we injured one to see what would happen". You have to be pretty twisted and psychopathic to think it's perfectly OK to carry these kinds of twisted experiments out, all in the name of human longevity. This is NOT ok. You should all be deeply ashamed. This is what makes the human race so deeply flawed, the torture and abuse of other sentient beings to extend our own lives. It should be illegal and punishable!!
In that case when you get sick do not allow the doctor to prescribe any drugs as they were all tested on mice.
We at Yuvan Research are way ahead, having produced multi-organ rejuvenation in living rats, and in one case (my own), in human skin. Turn Bio is only dealing with the symptoms of aging and not its cause. I wish them luck if we don't beat them, in which case I wish us luck because we have the solution ("E5")and proof that it works and want nothing more than to provide humankind with undreamed of opportunities. To extend youth is to delay the diseases of aging, and give people those "golden years" that people worked their whole lives for which now are increasingly painful and debilitating years and replace them with growing younger, ("youthening" as opposed to "aging"), regaining lost abilities or perhaps never losing them. This will mean revolutionary change for humanity as our methods are cheap, moral, and sustainable. Rejuvenation for the masses, not just the billionaires.
55:25 whatttttt?
Excellent talk. Thanks.
ive been using my near infrared light for my heroin addiction treatment for many years. It also can keep abscesses from getting infected also. It helped get me off of heroin. And the sun.
Hey hope you see this- how did you use it? And how frequently? I’m looking to kick suboxone
I enjoyed your literature review in the context of evolution. Interestingly, there is no inclusion for LGBTQ in the evolutionary model yet this phenomena survives very robustly. I wish that some researcher would examine these ideas.
You should check into work of Frans de Waal Books and recent podcasts.
Can this treatment will work for liver cancer? and does it work for patient that had their optic nerve damage in the eyes
thanks
I only know one product that my overall health can rely the most. It's NMN by Vitruvin Health. Cost-effective! 😇
I am almost 78 years old walk every day most times 2 miles every other days hit the gym bench press squat stay strong my friends to live long
I get the minimum everyday and cook real foods, not that hard to figure it out
Why was Jesus not around in evolution?
JC never excited Folklore and Fareytale and Fiction
Love it 🔥
Except Dr. Wallace, the panelists look so unhealthy. How can unhealthy people have any clue as to what makes a human healthy? <smh> Compare these people to Dr. Paul Mason, Dr. Brett Scher, Dave Feldman, Elliot Overton, etc. Just as I wouldn't take financial advice from broke people, when it comes to health, I wouldn't put much weight on the opinion of unhealthy people.
Great work!
They just had a recall on Metformin ua-cam.com/video/sJypWJ0KTPQ/v-deo.html.
Please put together a podcast with scientists addressing the Western Diet effect on killing mitachondria. Example, Corn Syrup injected in everything.
Yes second that. I take it you are familiar with the fructose work from Richard Johnson, Robert Lustig etc.?
42:00 metformin
She obviously missed the traditional Maasai (other traditional African societies) in our species millions of years long evolution, who without exercise maintain thin, healthy & happy lives with 45-55ng/ml year-round levels.
The Maasai are also mostly carnivore and walk everywhere
I thank God I was able to cure my Diabetes Type 2 that last for 3 years in my system with the help of Dr ONO herbal remedies. you can visit his UA-cam channel Dr ONO for more informatio
Metformin is a mitochondrial toxin that raises lactate which is not good. This is a flawed theory that will not die because too many researchers have put too much time and money into it.
This is very exciting research. This gives me hope for a better future. I wonder how long until science like this will manifest in something available to those with neurological diseases? 10, 20, 30 years?
Humans do have brown fat
I want to personally take time out to appreciate Dr IGUDIA on his UA-cam channel for the herbs medication I ordered from him in curing my Diabetes disease
Thank you for the video.
Excellent video! I found the dietary information unique and in line with my experience. I am a 77 yo man who feels better and am more active than I was 20 years ago. I walk 5 to 10 miles almost every day (sometimes 15 miles), and do body weight exercise daily. I tried some fasting but got concerned with the implications for nutrients, especially protein. So I eliminate sugar and processed carbs - almost eliminate but severely restrict - it's not a religion! I also take NMN and Metformin. My main concern is balance. That has deteriorated. I am looking for methods to improve that. I have a girlfriend who shares our walks and bed. I do analytics for a large health care group, with some experimenting in artificial intelligence. Thank you for a very thoughtful presentation.
People. The message here is more important than the messenger's ability to entertain. This is super interesting and important. Thanks for the knowledge.
No enough words can explain your kindness Dr IGUDIA on UA-cam who cured my Diabetes with his herbs medications