UW AI Teaching Series
UW AI Teaching Series
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5/28/24 - FDA Approved Peanut OIT and Anti-IgE Treatment for food Allergy
Stephen Tilles MD
Clinical Professor, University of Washington
OBJECTIVES:
Understand pivotal trial data from FDA approved food allergy treatments
2. Understand practical considerations when implementing food allergy treatments
3. Appreciate barriers that have delayed addressing the food allergy unmet needs
DISCLOSURES
Consultant: FARE, Stallergenes Greer, Nestle Health Science, Adovate, Jasper Therapeutics
Переглядів: 72

Відео

5/7/24 - Omalizumab and Other Food Allergy Therapeutics on the Horizon
Переглядів 1733 місяці тому
Dr. Sharon Chinthrajah Associate Professor, Acting Director of the Sean N. Parker Center for Allergy & Asthma Research Stanford University PRESENTATION OBJECTIVES: 1. Describe the clinical findings that led to the FDA approval of omalizumab for food allergy 2. Understand the clinical application of omalizumab for food allergy 3. Recognize therapeutic strategies on the horizon such as dupilumab ...
5/14/24 - B Cell Depletion and Immunodeficiency (What the Allergist Needs to Know)
Переглядів 1293 місяці тому
Niraj C Patel, MD, MS Associate Professor Pediatric Allergy and Immunology Duke University PRESENTATION OBJECTIVES: 1. Know the common causes of secondary immunodeficiencies (SID), including specific drugs 2. Recognize the immunologic evaluation of patients receiving B-cell depleting agents, and the indications for immunoglobulin replacement therapy in patients with SID 3. Know that vaccination...
5/21/24 - UW Allergy & Immunology Senior Fellow Research Presentations
Переглядів 673 місяці тому
SPEAKERS: Gabriel Mendoza, MD and Kelly Colas, DO, PhD Senior Fellows Allergy & Immunology, University of Washington Seattle Children’s Hospital PRESENTATION TITLES: Dr. Gabriel Mendoza: “They Really Need to See It”: Qualitative Study of Perspectives on Virtual Environmental Inspections for Individuals with Poorly Controlled Asthma Dr. Kelly Colas: A Quantitative Exploration of Maternal Perspec...
4/30/24 - Elevated Tryptase - Now What?
Переглядів 7824 місяці тому
PRESENTATION OBJECTIVES: 1. Describe the differences between mastocytosis and hereditary alpha-tryptasemia 2. Use tryptase calculations in the evaluation of mast cell activation 3. Describe the evidence based approach to mast cell activation syndrome management DISCLOSURES: Speaker: • Regeneron/Sanofi • AstraZeneca • Amgen • Optinose • GSK • Blueprint • Genentech Advisory Board Member: • Optinose
04/09/2024 - Eosinophilic Esophagitis: Pathogenesis, Treatments, and Endpoints
Переглядів 1604 місяці тому
SPEAKER Seema Aceves, MD, PhD Division of Allergy, Immunology Director, EGID Clinic University of California, San Diego Rady Children’s Hospital, San Diego OBJECTIVES: 1. Understand the presentation of EoE 2. Apply the appropriate treatment regimens 3. Discuss the complications and potential therapies DISCLOSURES: • Consultant/Speaker: Regeneron/Sanofi, Ferring • Research Support: Bristol Meyer...
3/6/24 Hot Topics in Infectious Diseases 2024
Переглядів 855 місяців тому
Shireesha Dhanireddy, MD Professor, Department of Medicine, Division of Allergy & Infectious Diseases University of Washington Director, Madison Clinic Director, Harborview Infectious Diseases & Travel Clinic Co-Founder, S.H.E. Clinic PRESENTATION OBJECTIVES: • Review updates in prevention and treatment of respiratory viral disease • Review epidemiology and management sexually transmitted infec...
4/2/24 Rhinitis: An Evolution in Treatment Options
Переглядів 995 місяців тому
Greg Davis, MD, MPH Rhinology & Endoscopic Skull Base Surgery Ear Nose & Throat Surgeon Clinical Associate Professor, UW Proliance Surgeons, Seattle & Puyallup WA Ear Nose Throat & Allergy Associate PRESENTATION OBJECTIVES: 1. Appreciate novel techniques to improve nasal congestion 2. Learn the options for treating post-nasal drainage DISCLOSURES: • Neurent Medical: Advisory Board and Research ...
3/19/24 - Is This Asthma or Not? Making an Accurate Asthma Diagnosis in Adults
Переглядів 2055 місяців тому
Ryan Murphy, MD Acting Instruction Division of Pulmonary, Critical Care & Sleep Medicine Center for Lung Biology, University of Washington OBJECTIVES 1. Recognize the value of a formal asthma definition, and how to consistently apply it. 2. Understand the most recent ERS and GINA guidelines regarding asthma diagnosis. 3. Practice utilizing a simplified approach to real life clinical cases. DISC...
2/20/24 - Aspirin Exacerbated Respiratory Disease in the Age of Biologics
Переглядів 1206 місяців тому
Katharine Woessner, MD, FAAAAI Clinical Professor and Division Head Allergy, Asthma and Immunology Scripps Clinic Medical Group PRESENTATION OBJECTIVES: 1. Recognize aspirin exacerbated respiratory disease 2. Know the updates in the current understanding of pathophysiology of AERD 3. Understand management options DISCLOSURES: • GlaxoSmithKline: consultant. Speakers Bureau • Astra Zeneca: consul...
02/13/24 "JAK" of All Trades, Master of Atopic Dermatitis?
Переглядів 5836 місяців тому
Dr. James Song, MD, FAAD Frontier Dermatology PRESENTATION TITLE: JAK of all trades, Master of Atopic Dermatitis PRESENTATION OBJECTIVES: 1. Recognize when one should consider the use of JAK inhibitors in treating atopic dermatitis 2. Appraise safety data for JAK inhibitors and discuss what this means in the context of dermatology 3. Discuss best practices for risk mitigation and improving pati...
2/7/24 - Natural History of Common Food Allergies
Переглядів 1336 місяців тому
Jocelyn Cooper Allergy/Immunology Fellow University of Washington OBJECTIVES • Understand the natural history of common food allergens • Recognize markers for persistence of IgE-mediated food allergy • Understand current strategies for altering the natural history of food allergies • Consider mechanisms for why some and not others have higher rates of resolution
1/30/2024 - FPIES: A Not So Rare Food Allergy
Переглядів 1,1 тис.7 місяців тому
SHYAM JOSHI, MD SECTION CHIEF, ALLERGY AND IMMUNOLOGY OREGON HEALTH AND SCIENCE UNIVERSITY • Identify and classify acute and chronic FPIES • List differences between the presentation of FPIES in adults versus children • Discuss the current understanding of FPIES pathophysiology
1/23/24 - Immunopathogenesis of Airway Responsiveness in Asthma
Переглядів 1107 місяців тому
Teal S. Hallstrand, MD, MPH, ATSF Professor of Medicine Medical Director, UWMC-ML Lung Function Testing Center Division of Pulmonary, Critical Care and Sleep MedicineUniversity of Washington 1. Understand the specific features of inflammation that are implicated in the regulation of endogenous airway hyperresponsiveness (AHR). 2. Learn about the precise location of innate immune cells in relati...
1/6/2024 - Venom Hypersensitivity: Recent Guideline Updates and Options for the Future
Переглядів 1157 місяців тому
Karen Anstey, MD Assistant Professor of Medicine Pulmonary, Allergy and Critical Care Oregon Health & Science University PRESENTATION OBJECTIVES: 1. Understand updates in guidelines for tryptase and c-KIT analysis in those with a history of venom allergy 2. Recognize factors associated with anaphylaxis severity that may influence venom immunotherapy 3. Describe component testing for venoms and ...
12/5/23 History of Allergy
Переглядів 959 місяців тому
12/5/23 History of Allergy
11/28/23 Genetic Testing's Role in Diagnosis & Care of Immunodeficient Patients
Переглядів 979 місяців тому
11/28/23 Genetic Testing's Role in Diagnosis & Care of Immunodeficient Patients
11/14/23 New Developments in Inborn Errors of Immunity
Переглядів 2359 місяців тому
11/14/23 New Developments in Inborn Errors of Immunity
11/8/23 Sublingual Immunotherapy for Inhalant Allergy
Переглядів 2019 місяців тому
11/8/23 Sublingual Immunotherapy for Inhalant Allergy
10/31/23 Health Inequities in Allergy and Immunology
Переглядів 7410 місяців тому
10/31/23 Health Inequities in Allergy and Immunology
10/24/23 The Quest for a Malaria Vaccine
Переглядів 9410 місяців тому
10/24/23 The Quest for a Malaria Vaccine
10/17/23 Hereditary Angioedema Overview
Переглядів 88910 місяців тому
10/17/23 Hereditary Angioedema Overview
10/10/2023 Updates on Anaphylaxis
Переглядів 24910 місяців тому
10/10/2023 Updates on Anaphylaxis
10/3/23 - Genetic Variation, BCG-induced Immune Responses, and Susceptibility to TB
Переглядів 25911 місяців тому
10/3/23 - Genetic Variation, BCG-induced Immune Responses, and Susceptibility to TB
09 26 2023 Current Research from the Panettieri Lab
Переглядів 5211 місяців тому
09 26 2023 Current Research from the Panettieri Lab
5/23/23 Clinical Food Allergy Research Updates Seattle
Переглядів 174Рік тому
5/23/23 Clinical Food Allergy Research Updates Seattle
5/16/23 Biologics in Asthma: Is Disease Remission Possible?
Переглядів 1,1 тис.Рік тому
5/16/23 Biologics in Asthma: Is Disease Remission Possible?
5/9/23 Non-IgE-Mediated Drug Allergies: An Update
Переглядів 350Рік тому
5/9/23 Non-IgE-Mediated Drug Allergies: An Update
5/2/23 Infectious Disease Updates for the Allergist
Переглядів 104Рік тому
5/2/23 Infectious Disease Updates for the Allergist
4/18/23 Is Asthma a Contributor to Dementia?
Переглядів 81Рік тому
4/18/23 Is Asthma a Contributor to Dementia?

КОМЕНТАРІ

  • @Cygx
    @Cygx 2 дні тому

    Basically the danger profile of Rinvoq (upadacitinib) and Cibinqo (abrocitinib) safety profile shouldn't be as severe as the black box warning because is it more selective and that it is possible for 20% of patients to be fully clear without the need of restarting the drug 25:02

  • @patthnerd6360
    @patthnerd6360 15 днів тому

    Man I'm sitting at home right now watching this I'm suffering from mcas,so dizzy I'm bed ridden I'm in Washington state, and went to hospital other night and they never heard of mcas,so I am screwed,having shortness of breath and dizzy and unsteadyness, no safe foods,smells heat and meds arnt working,

  • @menarussell
    @menarussell 26 днів тому

    20:26 Marking this chapter for future reference. :) Thank you for sharing this. I had the serum tests. I'm scheduled for the skin testing next.

  • @ElbertG-g6f
    @ElbertG-g6f 29 днів тому

    At last, watching my hives inflammation fade day after day until they completely vanished was such a relief, I went with what I pointed out and within the first 10 days or so the urticaria was barely visible! I just go'ogled the latest by Shane Zormander and after 20 days my skin has never been healthier!

  • @TabithaD-q5r
    @TabithaD-q5r 29 днів тому

    Well done, watching my hives inflammation fade day after day until they completely vanished was such a relief, I went with what I pointed out and within the first 10 days or so the urticaria was barely visible! I just go'ogled the latest by Shane Zormander and after 20 days my skin has never been healthier!

  • @ABC-fv7ow
    @ABC-fv7ow Місяць тому

    Superb.Thanks Doc 🎉

  • @jac1161
    @jac1161 Місяць тому

    perhaps along with MTHFR, patients should be screened for this before mandating shots and also before preventing patients from getting antihistamines during illnesses....

  • @pamnewton2160
    @pamnewton2160 Місяць тому

    What a waste of money at the Conventions! Been there, saw the waste. LOt of laughing going on, do you have Alpha 1?

  • @ranalloja
    @ranalloja 4 місяці тому

    Just add some HCL and poof, it's gone.

    • @AnmolSingh-qx2oc
      @AnmolSingh-qx2oc 4 місяці тому

      Are you using them every meal or day? Are you noticing any improvement?

    • @ranalloja
      @ranalloja 4 місяці тому

      LPR symptoms are gone. I used to take every day with meals (breakfast and dinner mostly, 600mg each) but now my gut is in better health so only occasionally when I feel a hint of LPR coming on or if I just feel like I should based on my eating habits at the moment. Bottom line is it worked, thankfully.

    • @AnmolSingh-qx2oc
      @AnmolSingh-qx2oc 4 місяці тому

      @@ranalloja that’s good to hear, which brand did you use?

  • @Collectingillusions
    @Collectingillusions 4 місяці тому

    More information for my personal alpha gal Bible! Thank you for the information, you will be cited 😀

  • @CarolReidCA
    @CarolReidCA 5 місяців тому

    Any thoughts on pain management in this patient? Opiates over other medications? What was the patient's genotype and phenotype? Thoughts on Methotrexate?

  • @jackiesicilian5720
    @jackiesicilian5720 5 місяців тому

    Has anyone looked into using amino acids to help control this issue

  • @francissobio1483
    @francissobio1483 5 місяців тому

    Very insightful presentation. Well done!

  • @jeanettebutler9535
    @jeanettebutler9535 5 місяців тому

    This is such deep information!! I’m Irish and my adult life I have been dealing with skin issues mostly my lower legs and arms. No one person was a solution. And my dermatologist wants use toxic meds or burn off in lesions.

  • @epfr19
    @epfr19 5 місяців тому

    I have been dying from pain from this disease. Last August I had developed so severe an atopic and nummular dermatitis (eczema) and was started on Dupixent. I just quit Dupixent because pain and inflammation in scalp and feet was still severe; I needed to treat my scalp every other day with 1% permethrin hair rinse which also helped my feet along with tiny bit of permethrin 5% cream. Last week I started on 1 mg daily Low Dose Naltrexone which has largely cured my feet and allowed me to use permethrin rinse less often and less urgently. I ordered low strength Ivermectin lotion yesterday to use with LDN. I may have been allergic to metal in dental reconstruction so I've removed some metal and zirconia upper fixed denture; I am toothless until I get metal Patch testing and Melissa blood test completed results in April 2024.

    • @davidsmusic31
      @davidsmusic31 3 місяці тому

      Please take JAK inhibitors! It's totally not worth going through immense pain..

  • @lamedvav
    @lamedvav 6 місяців тому

    Thank you. All risk and no benefit.

  • @Stella-ts8oj
    @Stella-ts8oj 6 місяців тому

    Have had bad reactions to about 20 medications. And doctors I’ve seen do not have a clue. My BP has become a problem. Medications are making me sick. Not just antibiotics.

  • @nancylindsay4255
    @nancylindsay4255 6 місяців тому

    I think the problem with allergists adopting this orphan disease is that we patients don't go to an allergist for our problems. ENT, GI, and pulmonology need to be on the front line. (But thanks, allergists, for caring! It's very interesting that you point out that allergists focus on treating the patient, no matter what/where the problem is.)

  • @nancylindsay4255
    @nancylindsay4255 6 місяців тому

    I'd like to know what is the reference "RAS" for Prolonged Cough following URI on the slide titled Other Manifestations (at 5:00).

  • @KARIS1961
    @KARIS1961 6 місяців тому

    Just. Wow! I learned sooooo much! I’m at my wits end with LPR. I can’t sleep. I can’t breathe. I’ve ended up in urgent care, unable to get air, with blue lips due to this condition. I’m hesitant to see an ENT. It’s a waste of money.

  • @patrickcephacile
    @patrickcephacile 8 місяців тому

    I want this doctor to help me because i think that's is my problem. And i am a singer

  • @suzybrose
    @suzybrose 8 місяців тому

    It is valuable to prevent you from going to ER and having poison ivy like response for three weeks after taking medications about 4 to 5 weeks that have ingredients you are allergic to. I brought my allergy results and they were basically ignored because m ost people do not have problems.. As I stood there with proof I have probems .. Not a problem til it is.. lol

  • @Sun-gj3cn
    @Sun-gj3cn 8 місяців тому

    Very helpful thank you

  • @AmruMagdy
    @AmruMagdy 9 місяців тому

    إِن يَنصُرْكُمُ اللَّهُ فَلَا غَالِبَ لَكُمْ ۖ وَإِن يَخْذُلْكُمْ فَمَن ذَا الَّذِي يَنصُرُكُم مِّن بَعْدِهِ ۗ وَعَلَى اللَّهِ فَلْيَتَوَكَّلِ الْمُؤْمِنُونَ

  • @Pattysifuentes150
    @Pattysifuentes150 10 місяців тому

    Thank you

  • @chrisperrywv
    @chrisperrywv 10 місяців тому

    I’ve watched several videos like this trying to get a handle on what exactly I’m doing to my body with this therapy. I can’t find an explanation on the mechanism of how this works to reduce the reaction is. Is it the same manner in which food/seasonal allergy therapy works?

  • @paulgent9203
    @paulgent9203 10 місяців тому

    This is very good

  • @NakatomiPurr-oo7ph
    @NakatomiPurr-oo7ph 10 місяців тому

    Amazing presentation but where the heck is a pepsin inhibitor/treatment? We can cure certain cancers but we don't have a pepsin inhibitor? How is that possible?

  • @dangnguyen7792
    @dangnguyen7792 10 місяців тому

    Thank you for your amazing presentation.

  • @kiwiscribe
    @kiwiscribe 10 місяців тому

    I found using a nasal spray of water and baking soda helps to clear it quickly.

  • @dayamitrasaraswati6276
    @dayamitrasaraswati6276 10 місяців тому

    Thank you for this video. I was recently diagnosed with HAE after having my one COVID vaccine and having a bad reaction. I am trying to understand this condition more. Videos like this are helping me in that regard. Thank you.

  • @fadihajjaj
    @fadihajjaj 11 місяців тому

    Thanks for sharing !

  • @zahraamohamned3396
    @zahraamohamned3396 11 місяців тому

    Begin in 9:16

  • @zakglobal8695
    @zakglobal8695 Рік тому

    Ar k n . Mn

  • @GKjones1991
    @GKjones1991 Рік тому

    It would be so nice to actually hear this rare and wonderful info.

  • @oliverfawnar-bc8gn
    @oliverfawnar-bc8gn Рік тому

    I have an ent prescribing Xanax for me! Because she checked my throat and everything looked fine. So she said just don’t think about it

  • @BrittKatSlat
    @BrittKatSlat Рік тому

    The cause of all these immune dysfunctions going off is an infection that is so stealthy it lives inside the host’s cells. They arent easily able to be eradicated so they stay and cause issues like asthma and even copd. Mycoplasmas and chlamydia pneumoniaes can do this.

  • @MaliaRoberts-ny1wm
    @MaliaRoberts-ny1wm Рік тому

    Thanks for the info, watching my hives inflammation fade day after day until they completely vanished was such a relief, I went with what I pointed out and within the first 10 days or so the urticaria/angioedema was barely visible! I just go'ogled the latest by Shane Zormander and after 20 days my skin has never been healthier!

  • @ConnieCornman
    @ConnieCornman Рік тому

    Well, watching my hives and inflammation dissolve every day until it all disappeared was definitely appeasing, I went with what I mentioned and after 20 days my urticaria/angioedema disappeared. I just go'ogled the latest by Shane Zormander and now my skin is as smooth and healthy as it has ever been!

  • @dayamitrasaraswati6276
    @dayamitrasaraswati6276 Рік тому

    I have HAE and cannot have the vaccines. I had one dose of Pfizer and had an attack. I had constant headache for one month slowly dissipating over the course of 3 months. I continued to have coughing due to the excess mucous and am only recently getting over that - 6 months after vaccination. My immunologist confirms I cannot have MRNA vaccines. I have not had another vaccine. It's difficult for me to get a lot of help here in Australia. Genetic testing is expensive.

  • @chadr2604
    @chadr2604 Рік тому

    I can tolerate taking a stanozolol once daily way better than having to be injected with 10,000$ medicine.

  • @chadr2604
    @chadr2604 Рік тому

    Isnt there politics when treating bradykinin? The medicine that works stanozolol is considered evil but its cheap and works. They want you to use the 10,000$ icatibant.

  • @Gala23Milk
    @Gala23Milk Рік тому

    Your channel is a godsend

  • @falbala435
    @falbala435 Рік тому

    Thanks for this presentation it's excellent. But nobody explains why the upper esophagus valve is not functioning properly. To me it's due to the vagus nerve. This nerve controls digestion and all the organs in the body. Stress can cause this disfunction, lack of sleep too, autoimmune disorders too. Check if you have other vagus nerve related diseases like pots, or parasites (lyme etc) /bacteria (pylori etc). Colloidal silver or ivm can help against parasites. I wonder if melatonin can help too as some people have reported on forums it cured their lpr. Pepsin is going up the throat so it's also a lower esophagus valve problem. I think the vagus nerve has a key role here. What do you think? Thanks

    • @falbala435
      @falbala435 Рік тому

      Anyway according to this presentation the best natural and non invasive treatments against this are: elevating the head of your bed, spraying baking soda water in throat, and alginate. The others involve surgery which is not so good taking into accounta the risks

    • @falbala435
      @falbala435 Рік тому

      Another possibility is stress which releases too much cortisol. The cortisol weakens many muscles, including the ones lining the esophagus and it is not a mere coincidence that GERD and LPRD usually start in the 3rd decde of life and increase with age. This coincides with the slowign of metabolism and the increase in cortisol/DHEA and cortisol/testosterone ratios, which leads to generalized atrophy and muscle loss and weakness.

    • @cynthiastogden7000
      @cynthiastogden7000 7 місяців тому

      Yes I agree totally about vagus nerve. I am a bit obsessed with researching it currently. I have had fibromyalgia for over 30 years and take Melatonin for sleep. It does help that but not the LPR. My coughing is exhausting all the time and I am super sensitive to everything like temp.changes, cleaning teeth, a small drink of water even. Good luck with your's.

    • @falbala435
      @falbala435 7 місяців тому

      @@cynthiastogden7000 thanks Cynthia and sorry for what you have to endure. Yes i do think it's a nervous problem either vagus nerve or neurotransmitters. I switched to a more holistic approach, since nothing "tangible " seems to work to alleviate the symptoms (diet, yoga, relaxation, ...). Good luck my friend

    • @brianpratt6988
      @brianpratt6988 5 місяців тому

      Yes, something called Post Viral Vagal Neuropathy from Covid. After Covid I got 100 day cough, then throat clearing then sore throats. Thinking it’s LPR now which I never had an issue with until after Covid.

  • @BLE000
    @BLE000 Рік тому

    I am on my 4th injection in the build up phase. I am struggling with severe anticipatory anxiety prior to each injection. Are there any recommendations, please?

  • @stephenaaa403
    @stephenaaa403 Рік тому

    You mentioned elevating the head of the bed by 6 inches. I have a 4 foot long wedge pillow that also reaches close to that. Is the elevating of the bed superior to a wedge pillow? Also, could you comment on the use of melatonin, as some have seen success with? My LPR started at the same time as my sleep issues began.

    • @brianpratt6988
      @brianpratt6988 5 місяців тому

      Bed elevation is the best. Wedge might be similar to pillow propping which they don’t recommend because your body is in a bent position.

  • @zakarialaklaai2140
    @zakarialaklaai2140 Рік тому

    Thank you

  • @blackpony7063
    @blackpony7063 Рік тому

    Can I please have a contact email please I have a few questions please?

  • @georgek7831
    @georgek7831 Рік тому

    Awesome talk, thanks for uploading!

  • @kelvinowen9559
    @kelvinowen9559 Рік тому

    *If you have problems with Herpes virus, I recommend you try **#DRERAYO** herbs on UA-cam, it has worked for most people know and 💯% safe* ✅✅✅✅