Відео

This video covers the classical pathway of complement activation, specifically how antibodies binding to pathogens can result in complement activation.

This video covers the function of neutrophils, how they become recruited to inflamed/infected tissues, and function to recognize and destroy pathogens.

This video covers proteins that can stimulate or dampen the complement activation, including factor P, facot H, factor I, MCP, and DAF (decay-accelerating factor)

This video presents the role of MBL (mannose-binding lectin) in initiating the lectin pathway of complement activation as well as the role of the classical C3 convertase and classical C5 convertase.

This video covers the classical pathway of complement activation, including the roles of CRP (C-reactive protein), the complement C1 molecule, and the formation of the classical C3 convertase and classical C5 convertase.

This video introduces the systemic effects of cytokines such as TNF-alpha, IL-1, and IL-6, especially on the liver in producing acute phase proteins such as CRP (C-reactive protein) and MBL (mannose-binding lectin).

This video introduces the local effects of cytokines such as TNF-alpha, IL-1, IL-6, and CXCL8 that are produced by macrophages upon detecting a pathogen.

This video introduces TLRs (Toll-like receptors), and their role in immune system signaling,

This video introduces macrophages, their locations, and receptors involved in phagocytosis,

This video covers one of the effector functions of complement activation: the formation of anaphylatoxins C5a and C3a, their effects on cells that express C5a receptor and C3a receptor, and how that triggers inflammation and boosts the immune response.

One of the effector functions of complement activation is the formation of the membrane attack complex. This video covers the formation of the MAC after complement activation by the alternative pathway, covering the alternative C3 convertase and the alternative C5 convertase

This video covers opsonization, specifically how pathogens can become opsonized after complement fixation.

This video introduces the alternative pathway of complement activation, covering how the pathogen is recognized by complement proteins, leading to the formation of both the soluble C3 convertase and and alternative C3 convertase.

This video introduced the complement system, including the three different pathways complement can be activated, complement fixation, and three complement effector functions.

Location of pathogens

Cells of the immune system

Introduction to immune tissues

Pathogens and immune system themes

Complement introduction and activation of alternative pathway

Result of complement activation - opsonization

Protein-protein interactions

Cell cycle analysis

RNAi knockdown technique

Types of vaccines, part 3: DNA vaccines, RNA vaccines, viral vectors

Types of vaccines, part 1: live vaccines

Types of vaccines, part 2: killed vaccines, subunit vaccines

Cell cycle regulation, part 6: Cdki regulation

Cell cycle regulation, part 5: Cdk Inhibitors

Cell cycle regulation, part 3: cyclin D, cyclin E, and Rb