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Type 1 and Type 2 DNA Topoisomerase | How Topoisomerase works | Molecular Biology🧬
#DNA Replication #ReplicationFork #Helicase #Topoisomerase #Topoisomerase types #Topoisomerase function #Topoisomerase mechanism #Topoisomerase Inhibitors
Enzyme Topoisomerase an extremely important enzyme in the human cells that is designed to remove supercoils in DNA strands that arise during replication and transcription. Without topoisomerases, chromosomes would become an impossible mess, making DNA replication, transcription, and cell duplication impossible. This video explains about enzyme DNA Topoisomerase involved in DNA replication, Its role in preventing supercoiling, Types of DNA Topoisomerase, their mechanism and Topoisomerase inhibitors and their clinical significance.
Переглядів: 1 261

Відео

End Replication Problem | Telomere and Aging | enzyme Telomerase Telomere Replication 🧬
Переглядів 1,1 тис.7 місяців тому
In this deep-dive video we discuss the DNA replication of telomeres, which are novelties for linear chromosomes, especially the eukaryotes. We understand the telomere structure, telomerase enzyme, and delve into the end replication problem.
DNA Replication | Molecular biology | Genetics | Cell Biology 🧬
Переглядів 1,2 тис.8 місяців тому
Biology- NEET - MBBS Prof 1 - BSc.- MSc #Dna Replication #ReplicationFork #DNAHelicase #Topoisomerase #Polymerases #tus-ter complex #Ligase #Primosome #Primase #primer Ever wondered how DNA is accurately copied in cells? This video breaks down the intricate steps of DNA replication, and the role of different enzymes and proteins in making the copy of a DNA molecule. I hope you enjoy this lectur...

КОМЕНТАРІ

  • @rayenaouni-o1d
    @rayenaouni-o1d 2 місяці тому

    "Great video! You did an excellent job explaining the roles of topoisomerase I and II in DNA replication. I now fully understand how topoisomerase I removes positive supercoils ahead of the replication fork, while topoisomerase II (gyrase) introduces negative supercoils behind the fork to relieve tension. The distinction between their actions and how they complement each other is much clearer to me now. Well done!"

  • @aayushjayswal6125
    @aayushjayswal6125 7 місяців тому

    Wow 😳

  • @piyushkumawat7804
    @piyushkumawat7804 7 місяців тому

    Nice 🙂

  • @avinashmarothiya6438
    @avinashmarothiya6438 7 місяців тому

    Nice video and clear explanation!

  • @mahendrakavar4827
    @mahendrakavar4827 7 місяців тому

    This is very much helpful... Thank you

  • @gouravprajapat7265
    @gouravprajapat7265 7 місяців тому

    Easy to understand thank you

  • @bhargavmoyal2227
    @bhargavmoyal2227 7 місяців тому

    Thanks a lot

  • @AmanSharma-kd1mc
    @AmanSharma-kd1mc 7 місяців тому

    very nice

  • @mohanpatel1189
    @mohanpatel1189 7 місяців тому

    That was very useful, finally I understood ...

  • @mahiravarma9459
    @mahiravarma9459 7 місяців тому

    Doesn\'t the RNA primer attached to the telomere sequence get removed eventually, too?

  • @sarukour5510
    @sarukour5510 7 місяців тому

    The best explanation for this topic

  • @AmanSharma-xj4ic
    @AmanSharma-xj4ic 7 місяців тому

    10/10 wonderful video

  • @ammyvirk8485
    @ammyvirk8485 7 місяців тому

    Thanks It really helped me

  • @lilisarkar5059
    @lilisarkar5059 7 місяців тому

    This was so easy to understand. Thank you so much!!

  • @aadityasani7039
    @aadityasani7039 7 місяців тому

    Very well done!

  • @nitinraika1987
    @nitinraika1987 7 місяців тому

    Finally can understand how lagging strand is replicated. Thank you!

  • @kishanvarma711
    @kishanvarma711 7 місяців тому

    Great video!

  • @rohankapoor2822
    @rohankapoor2822 7 місяців тому

    One of the most helpful video

  • @deepakchoudhary9379
    @deepakchoudhary9379 7 місяців тому

    one of the best videos on UA-cam

  • @laxitamoond1598
    @laxitamoond1598 7 місяців тому

    Thanks for explaining this complex mechanism so beautifully

  • @nikhilkumawat3317
    @nikhilkumawat3317 7 місяців тому

    Thanks a lot for such an amazing video

  • @rahulvarma1323
    @rahulvarma1323 7 місяців тому

    So simplified and yet all points covered.... Thanks a lot

  • @pramodchoudhary7073
    @pramodchoudhary7073 7 місяців тому

    awesome! Great explanation. Thanks for your helpful video

  • @mukeshnaga1117
    @mukeshnaga1117 7 місяців тому

    Thank you! This was super clear and straightforward

  • @zishankhan8054
    @zishankhan8054 7 місяців тому

    fantastic!

  • @mayankvarma3182
    @mayankvarma3182 7 місяців тому

    Thank you soooooo much

  • @maheshjaat9349
    @maheshjaat9349 7 місяців тому

    Thank you so much for this! Literally was struggling to understand this concept.Now it\'s crystal clear. Thank you

  • @aayushjayswal6125
    @aayushjayswal6125 7 місяців тому

    wow great thanks

  • @piyushkumawat7804
    @piyushkumawat7804 7 місяців тому

    easy and clear thank you

  • @avinashmarothiya6438
    @avinashmarothiya6438 7 місяців тому

    This really helped me. Thank you for the content.

  • @mahendrakavar4827
    @mahendrakavar4827 7 місяців тому

    Thanku....easily grasp

  • @satishgupta8140
    @satishgupta8140 7 місяців тому

    Thank you so much. This explanation was remarkable!

  • @amansharma-ss6pp
    @amansharma-ss6pp 7 місяців тому

    Absolutely great video

  • @anilsaini6765
    @anilsaini6765 7 місяців тому

    Very helpful animation! Thanks for showing visually

  • @sanjusharma8003
    @sanjusharma8003 7 місяців тому

    This is the best explanation I could\'ve ever got for DNA Replication

  • @panjavisingh2800
    @panjavisingh2800 7 місяців тому

    Thank you very much! very simple explanation

  • @AjaySharma-kd9br
    @AjaySharma-kd9br 7 місяців тому

    The best replication animation i have seen thanks a lot!

  • @siryaalli2757
    @siryaalli2757 7 місяців тому

    This was actually the only video that made me finally understand it..800d job :)

  • @diveshkumar8337
    @diveshkumar8337 7 місяців тому

    Thank you so much this was brilliant!

  • @khushalrajput1441
    @khushalrajput1441 7 місяців тому

    this is one of the best DNA replication videos I\'ve ever seen so far! Great visualization!

  • @meenanod5413
    @meenanod5413 7 місяців тому

    This video is just amazing !!!!