- 67
- 119 937
Ontario Neurodegenerative Disease Research Initiative (ONDRI)
Canada
Приєднався 30 вер 2014
The Ontario Neurodegenerative Disease Research Initiative (ONDRI) is a provincial collaboration studying Dementia and how to improve the diagnosis, treatment and outcomes of associated diseases including Alzheimer’s disease/Mild cognitive impairment, Parkinson’s disease, Frontotemporal Dementia (FTD), Amyotrophic Lateral Sclerosis (ALS) and Stroke.
ONDRI is carried out in partnership with the Ontario Brain Institute.
Learn more at ondri.ca
ONDRI is carried out in partnership with the Ontario Brain Institute.
Learn more at ondri.ca
Neurodegenerative Disease Biomarkers Through Pupil Response Times
In this short video, Dr. Doug Munoz, Queens University professor and ONDRI co-lead, explains how ONDRI researchers are making progress in developing biomarkers of neurodegeneration through the eye tracking platform.
Specifically, he reviews how multiple areas of the brain are involved in controlling eye movements, and how differences in pupil response rates to stimuli -- between healthy cohorts and cohorts of people living with #neurodegenerative disease -- can be indicators of disease present in the brain.
Video adapted from Dr. Munoz's presentation at the ONDRI research initiative's Community Engagement Day, January 2022.
For more: www.ondri.ca
Specifically, he reviews how multiple areas of the brain are involved in controlling eye movements, and how differences in pupil response rates to stimuli -- between healthy cohorts and cohorts of people living with #neurodegenerative disease -- can be indicators of disease present in the brain.
Video adapted from Dr. Munoz's presentation at the ONDRI research initiative's Community Engagement Day, January 2022.
For more: www.ondri.ca
Переглядів: 96
Відео
Understanding heterogeneity in neurodegenerative disease through ONDRI
Переглядів 122Рік тому
This talk, by ONDRI co-lead Dr. Mario Masellis, was given at the Canadian Open Parkinson Network (C-OPN) General Assembly, on October 17, 2022. Dr. Masellis describes the complex disease processes and phenotypes associated with neurodegenerative and cerebrovascular diseases. Included is a review of mixed diseases and co-morbidities seen in the late onset dementia and Parkinson's disease populat...
The blood brain barrier: focus on new molecular biomarkers
Переглядів 112Рік тому
This short video, featuring Dr. Doug Munoz, reviews the blood brain barrier and the unique function it serves in helping nourish and protect the brain. Newer technologies (e.g. SIMOA) allow researchers to detect molecules in the blood, even at very low concentrations. This is very useful in the context of neurodegenerative disease research. This video was a adapted from a longer presentation ma...
Tracking dementia biomarkers and disease progression
Переглядів 1152 роки тому
In this short video, Dr. Doug Munoz, Queens University professor and ONDRI co-lead, explains the progression towards Alzheimer's disease/dementia symptoms, from the preclinical stages, through to mild cognitive impairment, to the final diagnosis. Specifically, he reviews timelines through which various types of #biomarkers can be observed along the disease trajectory. These biomarkers include c...
Measuring non-wear in remote monitoring
Переглядів 532 роки тому
In this short clip, Kit Beyer, who works out of the University of Waterloo, reviews a novel method developed by ONDRI researchers, to measure non-wear of #wearable sensors, while remote monitoring. This novel method was published in a paper in the journal BMC Medical Research Methodology in May 2022.
ONDRI's Patient & Community Advisory Committee (PCAC)
Переглядів 782 роки тому
In this video, adapted from ONDRI's Scientific Retreat in June 2022, Christina Stergiou-Dayment, PCAC co-chair and Senior Director with the Alzheimer's Society of Ontario, reviews concepts relating to patient engagement in research, the importance of advocacy for the needs of people with lived experience, as well as the important role the PCAC plays in ONDRI's research
The HANDDS-ONT Dementia Study Protocol Review
Переглядів 3042 роки тому
This animated video provides the step by step protocol of the Core HANDDS-ONT dementia study, with voiceover and contact details. The study is recruiting participants who are living with alzheimer's disease/mild cognitive impairment, frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), Parkinson's disease and cerebrovascular disease/Stroke; and older adults living independently i...
The HANDDS-ONT Study Protocol and Lived Experience
Переглядів 672 роки тому
Dr. Richard Swartz, ONDRI co-lead, and Mr. Larry Linton talk about the experience of participating in the HANDDS-ONT study. The study is recruiting participants who are living with alzheimer's disease/mild cognitive impairment, frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), Parkinson's disease and cerebrovascular disease/Stroke; and older adults living independently in the ...
Health Services Research Through ONDRI's Aim 4
Переглядів 402 роки тому
Dr. Susan Bronskill and Laura Maclagan present on health services research conducted by the team, covering topics such as impacts of the COVID-19 pandemic on people living with dementia and Parkinson Disease in Ontario, the ER usage patterns of people living with dementia, among many other areas.
The Remote Monitoring Platform: ONDRI@Home
Переглядів 6792 роки тому
Dr. Bill McIlroy presents on the developments that have been achieved in remote monitoring of people living with neurodegenerative and cerebrovascular diseases, through ONDRI's research. Included is a deep dive into the health and activity reports that are being delivered to study participants through the #HANDDS-ONT study.
The Dementia Tsunami and Introduction to Biomarkers
Переглядів 1822 роки тому
This video features Dr. Mario Masellis describing the rise of dementia incidence, the complexity of diagnosing causal neurodegenerative and cerebrovascular diseases, and an introduction to molecular and other biomarkers studied by ONDRI Presentation recorded as part of the ONDRI Study Community Engagement event, January 25, 2022.
ONDRI's Molecular Platform
Переглядів 342 роки тому
In this presentation Dr. Doug Munoz, ONDRI co-lead, goes way down in the brain and explores the start of the disease processes in neurodegenerative disease, preclinical stages and when biomarkers show up.
Description of ONDRI@Home (Aim 2)
Переглядів 412 роки тому
In this short video Dr. William (Bill) McIlroy, Remote Monitoring platform lead, describes ONDRI's strategic advances in facilitating research and care in the home and community, leveraging advances in #wearables, miniaturization, battery power, #datanalytics and more. Excerpt taken from ONDRI's Community Engagement Day: January 25, 2022
My Experience Living with Parkinson Disease and Participating in HANDDS-ONT: Featuring Larry Linton
Переглядів 6612 роки тому
This video spotlights Mr. Larry Linton who reviews his experience living with young onset Parkinson Disease and participating in ONDRI's HANDDS-ONT Study. HANDDS-ONT provides you and if desired, your circle of care, with a 24/7 snapshot of your health related behaviours, which can inform self care and symptoms management. Recorded as part of the ONDRI Study Community Engagement Day, January 25,...
Feasibility of Multi-Sensor Remote Monitoring
Переглядів 732 роки тому
This short video features Dr. Bill McIlroy reviewing the extensive feasibility work carried out by ONDRI@Home to validate the number and location of sensors utilized in ONDRI's remote monitoring studies of people living with neurodegenerative diseases and dementia. Included is a brief review of background pilot studies, including ReMiNDD, and an introduction to the HANDDS-ONT study. Recorded at...
ONDRI Community Engagement Day 2021/22 - complete event recording
Переглядів 1372 роки тому
ONDRI Community Engagement Day 2021/22 - complete event recording
Alzheimer Society of Ontario: Introducing the HANNDS-ONT Study to Staff
Переглядів 872 роки тому
Alzheimer Society of Ontario: Introducing the HANNDS-ONT Study to Staff
ONDRI AIM 3: Validation Through Collaboration
Переглядів 243 роки тому
ONDRI AIM 3: Validation Through Collaboration
Introduction to ONDRI Data Pipeline and Processes
Переглядів 933 роки тому
Introduction to ONDRI Data Pipeline and Processes
Virtual Dementia Care in a Post-COVID-19 World
Переглядів 673 роки тому
Virtual Dementia Care in a Post-COVID-19 World
Shaking Things Up: VIRTUAL DEMENTIA CARE
Переглядів 2923 роки тому
Shaking Things Up: VIRTUAL DEMENTIA CARE
Dementia Dialogue podcast - Changing Roles in Dementia Research: from Subjects to Participants
Переглядів 543 роки тому
Dementia Dialogue podcast - Changing Roles in Dementia Research: from Subjects to Participants
The Dementia Experience: Frontotemporal Dementia (FTD)
Переглядів 35 тис.3 роки тому
The Dementia Experience: Frontotemporal Dementia (FTD)
Wearable Sensors and Health Monitoring Overview through ONDRI@Home
Переглядів 10 тис.3 роки тому
Wearable Sensors and Health Monitoring Overview through ONDRI@Home
Observations from ONDRI's home- and community based remote monitoring pilot studies
Переглядів 943 роки тому
Observations from ONDRI's home- and community based remote monitoring pilot studies
Show & Tell on remote monitoring technology and data collected through ONDRI@Home
Переглядів 813 роки тому
Show & Tell on remote monitoring technology and data collected through ONDRI@Home