Quantifying aging, rejuvenation & selenium - Vadim Gladyshev

[@TheSheekeyScienceShow]

This was recorded a few months ago, but I think everything is still up to date!

[@harikumarmuthu8819]

I have an out of context doubt. What tools do you use for making these videos ?

[@christopherellis2663]

A clear distinction between

[@rapamune]

One of my favorite interviews thus far, Vadim exudes scientific curiosity

[@peterz53]

Thank you for this excellent discussion with another great guest!

[@SlamminGraham]

The parabiosis experiments, specifically, have been done for decades. Haven't we learned a lot about their mechanism by now? Or still not?

[@edwhite2255]

Sinclair believes has defined aging and believes it can be slowed, stooped and maybe even reversed. I would love to see a discussion between the two

[@WildGamez]

Wow very Insightful

[@darkhorseman8263]

Can't believe how far behind the 8ball they are on some anti-ageing research subjects. The body has two modes. A normal mode, and a stress response mode, when the integrated stress response is over-activated.
Selenium helps the body run during these stress response modes, like regulating 'low oxygen blood production' and various other mechanisms.
The sirts activate to regulate energy production during these stress response modes as well, to keep the body working when things are breaking down.
This process even gives the primary mode time to regenerate, while this backup stress response mode is functioning. Selenium also focuses on 'low oxygen or oxygen depleted areas' more often, like the testis.
Look up a study called: Stress erythropoiesis: Selenium to the rescue! It's an animal model study, but you can find human studies showing it happens the same way in humans.
It's the same in Fish and Whales, but they use Selenoneine, a Selenium bound version of Ergothioneine, when they deep dive, and suffer depleted oxygen levels over long times. Furthermore, it helps their bodies cope with the stress responses.
Humans that eat Ergothioneine or Selenoneine have better responses to low oxygen stress responses. There are some compelling studies into the Inuits who eat whales.

[@movement2contact]

Hmmmm.......... 🤔

[@surfreadjumpsleep]

I know like duh it's totally obvious.

[@petermalmgren1207]

Thanks

[@movement2contact]

@@petermalmgren1207 Thanks 🙇

[@samuelclemons508]

@GENETIC BEAST C'mon . So how often , are you suggesting , that a muscle should be trained ?

[@richardnunziata3221]

We have done a lot of organ transplants have these organs aged or rejuvenated in relation to the body they where put in. This can also be done in transgenic animal lines where rejection medication is not needed.

[@agumonkey]

Thanks for your vids

[@igorsoarescanuto7155]

Could you please make a video about nanomedicine and nanotechnology and how they may impact aging research? Maybe nanobots may help kill senescent cells and regulate other things in our body?

[@christopherellis2663]

I looked up Se on the internet.
" Though you may never have heard of Selenium..." American education seems defective.