Scientist Stories: Frances Arnold, Directed Evolution and Protein Engineering

Evolution-the adaption of species to different environments-has created an enormous diversity of life. Frances Arnold has used the same principles - genetic change and selection - to develop proteins that solve humankind’s chemical problems. In 1993, Arnold conducted the first directed evolution of enzymes, which are proteins that catalyze chemical reactions. The uses of her results include more environmentally friendly manufacturing of chemical substances, such as pharmaceuticals, and the production of renewable fuels.
Frances Arnold was born and raised in Pittsburgh, Pennsylvania in the United States. She studied mechanical and aerospace engineering at Princeton University. She then continued her studies at the University of California, Berkeley, where she earned a doctorate in chemical engineering in 1985. She has subsequently worked at the California Institute of Technology. She became interested in energy technology early and formed a company in 2005 to produce renewable fuels.
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[@julzee111]

I love that you’re pulling down my comments faster than I can make them.

[@julzee111]

This woman is the definition of mad scientist

[@Farhan-co9he]

someone please fix that micophone

[@kakistocracyusa]

This is the.typical Chem E. Prof who spends far more time being an inspirational speaker and salesman than in the lab with her grad students.

[@xBris]

Well, she's got a nobel prize, so... Her science is actually fascinating and has a lot of promise. But anyways, I've met her, and she is indeed a terrible person to work with. Great science, terrible lab culture.

[@kakistocracyusa]

​@@xBris Huge advances in such physical methods as next-generation synchrotron sources, electron diffraction methods, and accompanying data analysis algorithms have allowed exponential advances in protein science due to the enabling accelerated discovery in protein crystal growth and characterization. Professors who are good at self-promotion can find many ways to jump in front of this parade.