Dopamine - Vasopressors & Inotropes - MEDZCOOL
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- Опубліковано 22 сер 2015
- Dopamine is a complex vasopressor and inotrope that acts on many receptors in the human body in a dose dependent fashion. Learn more about dopamine here.
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Amazing video. Short. Summarized. Straight to the point. Thank you sincerely.
Just the short and strait to the point video I needed for dopamine. Thanks!
Keep it up. Great style and brief narration
this is a DOPE way of discussing this topic.. thank you
Hey man, I love your videos, thank you for the information!
Thank you so much, it was very helpful
Great stuff!
Thank you 🙏🏻 excellent video
man i wish you were professor for all my classes...lovin your videos bro...hopin you keep making more videos...i have questions though i know that dopamine starts acting on beta one and alpha as dose increases....but my kaplan lecture notes says fenoldopam a d1 agonisg is used for severe hypertension...shouldnt it be hypotension???? confused here because if doponine act on beta and alpha 1 than there ll be vasoconstriction how does that help hypertension....
Thank you so much
Wonderful
It is totally lit. Thankyou!
Nice video.
I have a question,when we use some drugs we release dopamine and feel euphoria,but when we inject dopamine we don't feel it?
Why is that?
Thanks for the complement! The reason why you don't get a euphoria feeling when you inject dopamine used as a vasopressor is because this formulation of dopamine is not lipophilic. In other words, it does not cross from the blood stream, across the blood brain barrier and into the brain.
Thanks for the answer.So we act only on receptors of the autonomic nervous system.Same for adrenaline and noradrenaline?To cross the blood brain barirer we need deifferent but similar molecule,for example phenylethylamine class.I guess.Interesting stuff.
i have a question . How will dopamin affect the brain when it I can't cross the BBB?
+bana daboul if you are asking about dopamine’s effects as a neurotransmitter in the brain (with its effects on memory, euphoria etc.) it should not cause any of this.
Dopamine cannot cross the BBB unless given in the form of levodopa which is a dopamine precursor and can cross the BBB. Once Levodopa is in the brain it is converted to dopamine via decarboxylase. Levodopa is usually used on people with low dopamine levels or Parkinson’s disease.
Hi medzcool. Thanks for the video. when we give dopamine at >10mcg/kg/min, does the D1 and B1 effect still happen in addition to A1 effect? Thanks
Nur, yes at high doses you will still have D1 and beta effects!
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