Intro to Running Molecular Dynamics Simulations with NAMD (links to each section in description)

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  • Опубліковано 26 січ 2025

КОМЕНТАРІ • 39

  • @GianmarcGrazioliPhD
    @GianmarcGrazioliPhD  Місяць тому

    Since people often have issues getting VMD to work in the terminal, I created this video recently: ua-cam.com/video/lWPZAHQiTSs/v-deo.htmlsi=woZ44UP1dDg6UI2U

  • @CamiloRPZ
    @CamiloRPZ 9 днів тому

    Hey thank you for this great video!!

  • @krishnakumarpatel4079
    @krishnakumarpatel4079 3 роки тому +2

    Can't thank you enough! You are a hero.

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  9 місяців тому

      I’m so glad it was helpful, thank you for your message!

  • @setyantotriwahyudi4322
    @setyantotriwahyudi4322 3 роки тому +2

    Thank you Dr. Gianmarc .. Great Tutorial

  • @nickjojo4623
    @nickjojo4623 2 роки тому

    i can't change the directory in tkconsole even though it works for command prompt/terminal. Please help

  • @ikponwmosaobaseki3645
    @ikponwmosaobaseki3645 3 роки тому +1

    Thanks for this you really helped me

  • @abhiban66
    @abhiban66 Рік тому

    Thanks for posting.

  • @RAHULSINGH-bk3nf
    @RAHULSINGH-bk3nf 2 роки тому

    I am getting error for TCL namdcph
    Kindly help me to solve this problem.

  • @oktavialisti172
    @oktavialisti172 3 роки тому

    Hi sir, thank you for the video. I saw on the namd input script, you wrote run 2500, what is unit for that sir? does it show a step or what? for example, the step will be moved every 2 ps. meaning that the total simulations time is 2500 x 2 ps= 5000 ps?

  • @manjari3112
    @manjari3112 3 роки тому

    hello sir, thanku your tutorial helped me in simulating my protein with ligand. Is it possible to simulate one protein with multiple ligands using NAMD? Please reply.

  • @1998neet
    @1998neet 3 роки тому

    Can ubuntu have access such as discovery studio, molecular docking gold?

  • @anushkamahajan8186
    @anushkamahajan8186 3 роки тому

    Hi Sir,
    If I'm heating my system periodically from 0K to 300K, do I need to use Langevin Dynamics?
    What would happen if we don't use Langevin dynamics in NAMD config file?

  • @dianaa.valencia3910
    @dianaa.valencia3910 3 роки тому

    Hello. If I want to make a long simulation (100 ns) for publishing and also a docking, is this procedure appropriate? Or more steps are required? Thanks.

  • @joaoluismossri7526
    @joaoluismossri7526 3 роки тому +1

    Thanks a lot, Sir! That was very helpful!

  • @Neuronworld
    @Neuronworld 2 роки тому

    how to apply External electric field ON A Molecule using NAMD/ VMD

  • @maralafshinpour5539
    @maralafshinpour5539 2 роки тому

    Hi , Is there any tutorial for NAMD qm/mm?

  • @ongunpalaoglu3688
    @ongunpalaoglu3688 3 місяці тому

    can someone please help me, ı am unable to run text mode for vmd. it gives -bash: vmd: command not found. vmd -dispdev text -e ubq.pgn with this code on mac

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  3 місяці тому

      If you can open VMD with the mouse but not using ther terminal, then it sounds like maybe you don't have a correct alias for the vmd command in your ~/.bash_profile or ~/.bashrc file. I'm not 100% sure this is your issue, but I've seen students have symptoms like this before. VMD used to create the alias for you upon installation, but it doesn't seem to always happen automatically now. Good luck!

  • @ikponwmosaobaseki3645
    @ikponwmosaobaseki3645 3 роки тому

    what if u have multiple protein chains, will you run psfgen for each chain? if u do that you will have different pdb files how can u merge that?

    • @mudgalsdiary
      @mudgalsdiary 3 роки тому

      Google topotools mergemol VMD, you will get a TCl script. You can use that to merge them.

    • @ikponwmosaobaseki3645
      @ikponwmosaobaseki3645 3 роки тому +1

      @@mudgalsdiary thanks

  • @Selfhealing-bt1qk
    @Selfhealing-bt1qk Місяць тому +1

    Thanks for sharing. I want that files

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  Місяць тому

      @@Selfhealing-bt1qk you’re very welcome! the links to the files are in the video description

  • @farhadzrarahmed1819
    @farhadzrarahmed1819 2 роки тому

    Hello Sir. your video is really helpful, thanks. l am a new user MD simulation using LAMMPS packages. If you know about running a system using LAMMPS instead of NAMD and could be described it in a short video. I would be very appreciated it.

  • @shovansarker5403
    @shovansarker5403 3 роки тому

    What temperature should I choose while designing drug for human? Some say it should be 310k as human body temperature other say 300k.

    • @dianaa.valencia3910
      @dianaa.valencia3910 3 роки тому +2

      I've seen 310 K in many works, so I think it'll depend on your system. But I guess all the simulations try to be closest to real as possible.

    • @ALEJO29905
      @ALEJO29905 3 роки тому +1

      It should be 310k. It's a human body temperature.

  • @dianaa.valencia3910
    @dianaa.valencia3910 3 роки тому

    Hello. Which version of NAMD do you have?

  • @paulocarvalho5688
    @paulocarvalho5688 Рік тому

    Thanks for the video. Could you make a video teaching how to enable the GPUs? Additionally, could you do a simulation with one GPU and then with more than one GPU? Will simulation with more than one GPU be faster than with just 1? If the result is the same, how do you configure NAMD to use all GPUs?

  • @bettygao2704
    @bettygao2704 3 роки тому +1

    thanks!!!

  • @castilloh.gianmarco1048
    @castilloh.gianmarco1048 8 місяців тому

    gozuuu

  • @meitadea3765
    @meitadea3765 3 роки тому

    hello sir, is this the overall design of molecular dynamics?

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  3 роки тому +1

      This is a demo where I am running through a tutorial specifically for the NAMD molecular dynamics software package.

    • @godwinir712
      @godwinir712 3 роки тому

      @@GianmarcGrazioliPhD Respected sir..I couldnt acess into the Charmm Gui web server from my personal mail and I am not provided with affiliation mail..could you please help me out..?Or is there another way to generate files..?

  • @zainabahsan2369
    @zainabahsan2369 3 роки тому

    Showing this problem during MD_Run.namd Info: USING ARITHMETIC MEAN TO COMBINE L-J SIGMA PARAMETERS FATAL ERROR: UNKNOWN PARAMETER IN CHARMM PARAMETER FILE ./toppar_water_ions.str LINE=*set nat ?NATC* FATAL ERROR: UNKNOWN PARAMETER IN CHARMM PARAMETER FILE ./toppar_water_ions.str LINE=*set nat ?NATC*