Receptors: Types & Functions
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- Опубліковано 27 тра 2024
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Video Summary:
Receptors receive signals from cells exterior. They have a ligand-binding domain to recognize specific ligand and an effector domain to produce the downstream effect. Receptors for hydrophilic signal molecules are located on the cell membrane and receptors for hydrophobic molecules are located inside the cell. Various types of receptors are ligand-gated ion channels that regulate the opening or closing of the channel. G protein-coupled receptors act through G proteins and ultimately regulate the function of a wide range of enzymes and ion channels. Catalytic receptors mostly activate or inactivate a protein by phosphorylating or dephosphorylating them and Nuclear receptors serve as transcription factors.
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DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
Good tutorial about intracellular signaling mechanism....
I just wanna add few notes like
1) GPCR can be downregulated by activating Beta-Arrestin protein
2) Catalytic or enzymatic or one pass receptors are of four sub types...
A)Tyrosine kinase receptors [Dimeric :eg is NGF,BDNF etc are working through it, & Tetrameric like Insulin receptor]
B) Tyrosine kinase associated JAK-STAT receptors pathways through which all the cytokines & Erythropoietin act
C) Serine-Threonine receptors: TGF-beta acts through
&
D) Cyclic- GMP meadiated rec through which NO, VIP act...
Thank You for the addition, something to definitely research further
really good effort made, bravo
Nice explanation sir. I had missed this lecture from college but now I have a general idea about all type of receptors. 💜🌼
These videos are amazing. Keep up the good work 👍
So useful, dont stop..continue bro..
Excellent! Thank you. Please make more videos :D
Sir please add more videos of chapter pharmacodynamics.... Ypur videos are very helpful... 🙏🙏🙏
Brilliant! Thank you!
Thanks for sharing your knowledge on receptors
My pleasure
Your videos are so useful thank you so much ❤️ hope u can make more about pharmacodynamics you will help a lot❤️
Of course!!
Great work😊
u have really made it as easy as watching cartoons.thank u so very much
Most welcome 😊
thanks it helped a lot :)
Thank you
Nice video 👍👍👍👍
Very fruitful information
Thanks. Please share the video. We need your support to be able to keep making the videos.
Wow thanks
Pls create more physiology videos and also other medical school subjects videos
Yes. I am regularly uploading videos
Thanks a lot 🙏🏻
Most welcome. Please share 😊
Sir plz make more videos on pharmacology topics
There already are many videos on pharmacology.
Wonderful
Thank you! Cheers!
They do transport molecules, why aren't they transporters?
And what are types of transporters then??
Reception and transportation are two different functions. The classification is based on functions. Some molecules do both the functions e.g. ligand gated channels , so they are included in both, transporters and receptors. But not all transporters are receptors and not all receptors are transporters. Hope you get it.
@@NonstopNeuron what's the difference between their functions?
Receptors are for receiving signals (Watch video on cell to cell communication for more detail). And transporters are for transporting molecules across cell membrane (watch video on transport across cell membrane for more detail).
@@NonstopNeuron thank you so much for helping us🌷🌷
How about some actual knowledge as to how these cartoons are made? How is this all observed?
I follow the same creation work flow as followed by all professional studios to create animations. You can search on web how animations are created. It's huge area on it's own. Regarding "observation" the visuals that I use are metaphorical. What's actually observed is biochemical reactions. I hope that's what you meant.
Accent is very hard to understand smh ..