Bronchodilators Part 1: Principles of Respiratory Airflow and Development of Selective Drugs

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  • Опубліковано 27 лис 2022
  • With immunomodulation covered, it's time to dive into pharmacology of pulmonary activity. First up is bronchodilators. These address resistance in the bronchus and bronchioles that impede respiration, such as with asthma, emphysema, and bronchitis. This can be achieved through beta-2 adrenocepter agonism and muscarinic receptor antagonism. What are these receptors, what are their endogenous agonists, and how do bronchodilators interact with these receptors?
    Script by Michael Keith
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КОМЕНТАРІ • 32

  • @waelfadlallah8939
    @waelfadlallah8939 Рік тому +22

    It's just amazing the wide scientific coverage this channel provides 🤯

  • @SergeiTheAnarch
    @SergeiTheAnarch Рік тому +1

    Great job Prof! Excellent job explaining SARS for drug development, it's a very common method.

  • @mjjoe76
    @mjjoe76 Рік тому +4

    This helps explain why over the counter asthma medication made me twitchy and jumpy.

  • @archivist17
    @archivist17 Рік тому

    Thanks Dave. This is a great explanation.

  • @AdeptALot
    @AdeptALot Рік тому +1

    Great job prof.!!!!! I enjoyed a lot and waiting for ur next in pharmaco

  • @rogebel11
    @rogebel11 Рік тому +1

    Thanks!

  • @aashishgautam9217
    @aashishgautam9217 4 місяці тому

    Bht bdia ustad ji

  • @pedroequis9396
    @pedroequis9396 Рік тому +2

    Good job Professor Dave ! Looking forward to your next class.

  • @yaseenkhoso05
    @yaseenkhoso05 Рік тому

    Good 👍

  • @shadowmax889
    @shadowmax889 Рік тому

    B3 is also found in the wall of the bladder, the detrusor muscle, decreasing its contractility. B3 receptors are the target for the drug Mirabegron and is indicated to treat overactive bladder

  • @sciencenerd7639
    @sciencenerd7639 Рік тому

    wow!

  • @CGFillertext
    @CGFillertext Рік тому

    Very informative!

  • @_tim4e
    @_tim4e Рік тому

    Hey, does anybody know any good websites that provide information about the pharmacodynamics, pharmacokinetics, etc. of specific drugs and have a large database(except for Wikipedia)?

  • @-JA-
    @-JA- Рік тому

    👍👏

  • @SubjectSigma18
    @SubjectSigma18 Рік тому

    Just a couple of days I had to make an essay related to my asthma to my p.e teacher

  • @nirmalmishra6404
    @nirmalmishra6404 Рік тому

    Sir kindly make a video on Fajan's rule.

  • @homosapien5684
    @homosapien5684 Рік тому

    Please do a series on differential equations

    • @eatshitlarrypage.3319
      @eatshitlarrypage.3319 Рік тому +1

      Psst: ua-cam.com/play/PLybg94GvOJ9ELZEe9s2NXTKr41Yedbw7M.html

    • @homosapien5684
      @homosapien5684 Рік тому

      @@eatshitlarrypage.3319 thanks, but this doesn't have differential equations

  • @desmond3828
    @desmond3828 Рік тому

    immune system!!!

  • @germangoblin3203
    @germangoblin3203 Рік тому

    Could you pls make a video about EHS (electromagnetic-hypersensitivity) and 5G?

    • @eatshitlarrypage.3319
      @eatshitlarrypage.3319 Рік тому

      No such thing. 5G uses frequencies within 4.10 * 10^8 Hz to 7.125 * 10^9 Hz and 2.425 * 10^10 GHz to 7.1 * 10 ^ 10 Hz. Visible light, for comparison, is 7.5 * 10^14 Hz to 4.2 * 10^14 THz. If people were sensitive to 5G, just being in a lit room would be overwhelming agony. There are no direct dangers to people from 5G. That being said, there are some other legitimate issues it causes, such as causing interference for water vapor detection methods (used in weather tracking), as well as issues with airplanes. Photons without enough energy to ionize atoms pose no threat.

    • @germangoblin3203
      @germangoblin3203 Рік тому

      @@eatshitlarrypage.3319 yeah I meant he should debunk it

  • @nebulan
    @nebulan Рік тому

    Some of these graphics make my lungs hurt... it's been a bad fall for my asthma :(

    • @bazinga1831
      @bazinga1831 Рік тому

      okay

    • @Donsomebody
      @Donsomebody 7 місяців тому +1

      I get bad during the winter due to the cold air. All the best for your asthma treatment

  • @livingcodex9878
    @livingcodex9878 Рік тому

    おはようございます

    • @janefrost1856
      @janefrost1856 Рік тому

      Good morning to you from the UK, I wish you well