The one thing I would like to see added to this excellent lecture, is the final linkage of the electron transport chain, ie definition of the actual "energy" released by the breaking of the phosphate bond, I presume its electrons as per a chemical battery?
How do molecular machines like triple-A ATPases work? It is known that they do work upon the hydrolysis of ATP+H2O to ADP+Pi, but how is this converted into mechanical energy? And how comparable are these -30 kJ mol-1 compared to the constant random noise of the environment these molecular machines are in?
Much better understanding.i can put things together better.but one question is what happens to the -11kj and the other thing is what is the purpose of adding the phosphate to the glucose since the energy seems to already be released and the phosphate has no energy or value
The -11kJ is lost as heat. Adding the phosphate has other uses - the next enzyme (phosphoglucose isomerise) in the pathway will only recognise G6P - it can't act on glucose directly. Phosphorylation of the glucose also adds a higher energy bond to the molecule which will be use later on in the pathway to make ATP via substrate level phosphorylation - there is an investment in energy in the early stages which is recaptured in the later reactions. Hope that helps!
Yes its very helpful.it has made so much more sense.everyone gives the steps of glycolisis with maybe little details at times but never quite answering the purpose of phosphorylation of glucose and what actually occurs.and without proper explanation,these things seem to contradict themselves like I said.this is such great help.i searched everywhere and everyone seems to just expect you to make sense of it all .but this is part of what separates a great teacher from a good teacher.you saved me so much work and stress.i am in much debt and very grateful to you.keep up the good work you do.
i was losing my mind over the fact i didn't understand this and you cleared it up in under 15 minutes. i hope you're having an amazing day
Katharine.God bless your mother
This helped SO MUCH I was going mad over my lecture slides but this was amazing. Thanks a lot
I love how you explained it like I am a 5 years old. I could understand it better that way. Thank you.
Thank you!! You explained the role of ATP and energy coupling very clearly!
that perfect as hell you must get much much mre
mybe if you make playlist according to lippincot or harper , will be ammzing
How u made it easy is AMAZING!
It's good listening to you, Katharine.
It's help me a lot. Thank you!
This is helpful. Thanks alot. From Nigeria
Excellent explanation, clear diction, good training aid, learned the example process easily. Thank you.
Thank you so much!!
Thank you so much ✌️🤗this is so helpful 😊
Thank you so much this is extremely helpful! ⭐🌟✨
Thanks so much ma❤
Thanks for that what a good teacher thank you so much
thank you!!
The one thing I would like to see added to this excellent lecture, is the final linkage of the electron transport chain, ie definition of the actual "energy" released by the breaking of the phosphate bond, I presume its electrons as per a chemical battery?
very nicely explained by you my lovely maam
Thank you 💖
thank you
POV this is not the first video you have watched trying to understand this
Ty💕
How do molecular machines like triple-A ATPases work?
It is known that they do work upon the hydrolysis of ATP+H2O to ADP+Pi, but how is this converted into mechanical energy?
And how comparable are these -30 kJ mol-1 compared to the constant random noise of the environment these molecular machines are in?
please give lecture on carboxylation and decarboxylation
god bless u
Much better understanding.i can put things together better.but one question is what happens to the -11kj and the other thing is what is the purpose of adding the phosphate to the glucose since the energy seems to already be released and the phosphate has no energy or value
The -11kJ is lost as heat. Adding the phosphate has other uses - the next enzyme (phosphoglucose isomerise) in the pathway will only recognise G6P - it can't act on glucose directly. Phosphorylation of the glucose also adds a higher energy bond to the molecule which will be use later on in the pathway to make ATP via substrate level phosphorylation - there is an investment in energy in the early stages which is recaptured in the later reactions. Hope that helps!
Yes its very helpful.it has made so much more sense.everyone gives the steps of glycolisis with maybe little details at times but never quite answering the purpose of phosphorylation of glucose and what actually occurs.and without proper explanation,these things seem to contradict themselves like I said.this is such great help.i searched everywhere and everyone seems to just expect you to make sense of it all .but this is part of what separates a great teacher from a good teacher.you saved me so much work and stress.i am in much debt and very grateful to you.keep up the good work you do.
At 3.01 how is the bond broken????
This is wrong, Ribose doesn’t connect to the Carbon, it connects to the Nitrogen on adenine.
You are indeed correct - the bond is to the nitrogen. Apologies!
IF YOU DON'T USE THE CHEMICAL EQUATIONS, YOU MISS HALF OF THE STORY.
Ty💕