PyMOL ligand-protein interactions | PyMOL tutorial | Protein Data Bank | Basic Science Series

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  • Опубліковано 5 жов 2024

КОМЕНТАРІ • 64

  • @Shadow-bx8ri
    @Shadow-bx8ri 2 роки тому +4

    Your content and way of explaining is out of the world sir. Thanks a lot for clearing out long term doubt.

  • @Amir-jn5mo
    @Amir-jn5mo Рік тому +3

    Amazing video. I had no clue what to even do in pyMOL as it looked intimidating. Now I can easily clean up a protein and focus on presenting the binding pocket im interested in

  • @egowong317
    @egowong317 9 місяців тому +2

    This is very helpful - thank you very much Professor!

  • @adampruska1738
    @adampruska1738 Рік тому +1

    Thank you very much. It was really helpful and speeded up my work efficiency with PyMol

    • @BasicScienceSeries
      @BasicScienceSeries  10 місяців тому +1

      Glad it helped! Thank you for your valuable feedback!

  • @DocScoop7
    @DocScoop7 6 місяців тому +1

    it was so helpful that i immediately subscribed the channel!! sending love from Shanghai

  • @bangnikabang6501
    @bangnikabang6501 Рік тому

    oh my God. sir, I love you. everywhere else the instruction is so sparse and general. thank you !!!

  • @marufislam3777
    @marufislam3777 Рік тому +2

    Thank you so much, sir. Can we get more tutorials as you said in this video? Like: "Finding the residues in the ligand binding pocket."

  • @manishmishra9177
    @manishmishra9177 2 роки тому +7

    show sticks, byres all within 5 of ligand
    For those who coudn't see the screen like me. copy paste this cmd

    • @BasicScienceSeries
      @BasicScienceSeries  2 роки тому +2

      Use laptop if you want to watch the video it won't be helpful with mobile phones. Thanks for your comment 🙏🏼

    • @manishmishra9177
      @manishmishra9177 2 роки тому

      @@BasicScienceSeries Can you make a video on how to calculate the volume of substrate binding site? Thanks in advance... :)

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 8 місяців тому

      Thanks, it helps alot. English is not my first language, so it sounds unclear to me.

  • @robertmuller1881
    @robertmuller1881 Рік тому +1

    Very clear - thank you

  • @vigneshpandi5722
    @vigneshpandi5722 2 місяці тому +1

    Thanks 😊

  • @manognak7406
    @manognak7406 16 днів тому +1

    HELLO Sir, thanks for this amazing tutorial. How will we know what chains to delete in the protein molecule? ( If the chains are non identical). Is there any criteria for that? Also, can a ligand be in its 2D form for docking?

    • @BasicScienceSeries
      @BasicScienceSeries  7 днів тому +1

      Well by manually selecting the chains and then go to remove object

  • @imenfathallah5788
    @imenfathallah5788 2 роки тому +1

    thank you for this video

  • @matthewadihonneyamos8723
    @matthewadihonneyamos8723 2 роки тому +1

    thank you, sir!!

  • @vamsivardhan5403
    @vamsivardhan5403 4 місяці тому +1

    The tutorial was absolutely fantastic and made to involve more but I could not find the link for the continuation of this video regarding labelling for each residue,, can anyone share the continuation of this video link plzz

    • @BasicScienceSeries
      @BasicScienceSeries  4 місяці тому +1

      Will try to make more useful more, stay tuned for more 🙏🏻🙏🏻Thank you

  • @luluingram3735
    @luluingram3735 2 роки тому +1

    life saver

  • @Fordance100
    @Fordance100 3 місяці тому +1

    Good video. Fonts are too small.

  • @sarinasarina3973
    @sarinasarina3973 2 роки тому +1

    thank you sir. everything is going well except when tap the bottom"S" at the underside bar no sequence information occured.

    • @BasicScienceSeries
      @BasicScienceSeries  2 роки тому +1

      So nice of you : ) Thank you so much for your kind support and for your comment as well.. It should work if you are not able to get the sequence, try reinstalling the software again.

  • @Yellownealy
    @Yellownealy 11 місяців тому +1

    Can you do protein-protein binding affinity? Like binding sites of an antibody to a particular cell-surface protein?

  • @israthumayunslifeinchina4996
    @israthumayunslifeinchina4996 4 місяці тому +1

    show sticks, by res all within 5 ligand
    i was write according to your information but residues not coming, in your video it is also not clear, can you please give me detail

    • @BasicScienceSeries
      @BasicScienceSeries  3 місяці тому +1

      Can you provide more details on the issue what command you are following ??

  • @dhruvipatel4144
    @dhruvipatel4144 Рік тому +1

    Hello sir, how do we get XYZ coordinates of a particular ligand and it's interaction with other molecules on the PDB?

  • @fatimagenetics
    @fatimagenetics Рік тому +1

    i need to watch next part,,,
    kindly provide me i haven't found

  • @karenluiselang3423
    @karenluiselang3423 3 роки тому +3

    Dear, what's the comand for select the residues close to the ligant? Thank you very much.

    • @BasicScienceSeries
      @BasicScienceSeries  3 роки тому +2

      Check this on out, number of commands with examples: pymolwiki.org/index.php/Selection_Algebra

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 8 місяців тому

      yes, since the picture is not clear enough to see 😢

  • @waqi409
    @waqi409 Рік тому +1

    The command is not clearly visible mention in the comments, please

    • @BasicScienceSeries
      @BasicScienceSeries  Рік тому

      Please check the comment section, if it is not posted already, let me know thanks 🙏🏼

  • @amalelfoly5944
    @amalelfoly5944 10 місяців тому +1

    could you please write the command of show sticks you used

  • @aneeshaanilkumar3935
    @aneeshaanilkumar3935 6 місяців тому

    Sir How to design anti drug conjugation

  • @alchemista947
    @alchemista947 2 роки тому +1

    when i select chain the ligand also selected i dont know why

    • @BasicScienceSeries
      @BasicScienceSeries  2 роки тому +2

      Thank you so much for your kind support and for your comment as well.. You need to select the residue option not the chain option at the bottom of the right corner. Play around I am sure you will figure it out. Which molecular you are exploring...

  • @JohnathonDubourg-g6k
    @JohnathonDubourg-g6k 18 днів тому +1

    Erica Extensions

  • @fatimagenetics
    @fatimagenetics Рік тому +1

    provide me link of next video

  • @AmyAnderson-f6g
    @AmyAnderson-f6g 23 години тому

    Boehm Spring

  • @TrudyMarquez-c3p
    @TrudyMarquez-c3p 12 днів тому

    Crist Forges

  • @SharlaClonch-k1f
    @SharlaClonch-k1f 22 дні тому +1

    Moshe Trail