The ABCs of Androgen Deprivation Therapy

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  • Опубліковано 2 лют 2025

КОМЕНТАРІ • 28

  • @stevemetts6206
    @stevemetts6206 2 роки тому +6

    This is one of the best presentations on ADT Therapy I have seen. I better understand, what I am going through, what is causing my side affects. My doctor, hasn't taking the time to explain this whole process, and I've been on ADT for over a year

    • @robwells230
      @robwells230 Рік тому

      I seriously doubt that your doctor told you how little overall survival benefit results from ADT...
      ...or that there are very serious quality of life destroying, and life threatening effects,
      ..that there is a twenty percent chance in older men that their testosterone levels will NEVER RECOVER and that they will remain castrated for life.
      ......or that many men find the cruel and barbaric chemical castration treatment to be INSUFFERABLE and refuse to accept or continue this horrific treatment..
      Please don't believe the BIG PHARMA SALES PROPAGANDA, and gather ALL THE FACTS, so you can carefully weigh benefit vs. risk , and only then can you give your FREE AND FULLY INFORMED CONSENT.
      Good luck with you journey. You are not alone

    • @robwells230
      @robwells230 5 місяців тому

      This presentation hides many of the true facts about this cruel and barbaric treatment such as
      Permanent penile atrophy
      Permanent testicular atrophy
      ...long term or permanent CASTRATION because Testosterone Doesn't recover.

  • @richardrosebealprestonjohn3144
    @richardrosebealprestonjohn3144 3 місяці тому +1

    Brilliant explanation!

  • @edwardkirby7679
    @edwardkirby7679 2 місяці тому

    Clear and insightful presentation.

  • @rhyothemisprinceps1617
    @rhyothemisprinceps1617 5 років тому +6

    Would fasting (or a fasting mimicking diet) during the intermittent ADT treatment period improve efficacy?

  • @derekness7900
    @derekness7900 5 місяців тому

    Really good presentation-thanks

  • @michaelyarmas4423
    @michaelyarmas4423 Рік тому +2

    Why cant Non-extensive metastatic disease be treated Intermittently? I am on Eligard+ Abiraterone my psa dropped to 0.018
    I would like to try Intermittent therapy but I am being told no as in your slide at 18 min mark

  • @rickrick5041
    @rickrick5041 4 роки тому

    Very good presentation

  • @Doctor9599
    @Doctor9599 5 років тому +1

    Thanks for everything Sir

  • @anilmehta6425
    @anilmehta6425 Рік тому +1

    ADT means (although effective) EDT energy ( whichever remained ) deprivation therapy

    • @robwells230
      @robwells230 5 місяців тому +1

      Call it what it is
      LONG TERM OR PERMANENT CASTRATION

    • @AnilMehta-mf6vg
      @AnilMehta-mf6vg 4 місяці тому

      ​@@robwells230right

    • @AnilMehta-mf6vg
      @AnilMehta-mf6vg 3 місяці тому

      ​@@robwells230yes right

  • @williamtucker709
    @williamtucker709 3 роки тому

    Thank you doctor

  • @briangriffith2394
    @briangriffith2394 3 роки тому

    Thank you so much doctor

  • @peterh4446
    @peterh4446 2 роки тому +1

    I thought testosterone converted to dihydrotestosterone, which the converted to estradiol, which is what actually nurtures the cancer cells. Correct?

    • @Dlindo8892
      @Dlindo8892 Рік тому +1

      That’s what I’ve always heard too. There’s no way in hell I would ever take these drugs!

  • @rhyothemisprinceps1617
    @rhyothemisprinceps1617 5 років тому +1

    So I came up with this brilliant theory after thinking to myself, now if I were a cancer gene in a tumor cell or cancer stem cell, how would I spread myself all over (explaining why sometimes treatment resistance just seems to explode). I would make myself into a transposable element and package myself into an exosome... I checked PubMed, and, yup, people are already working on 'my' theory:
    www.ncbi.nlm.nih.gov/pmc/articles/PMC3040683/
    Perhaps a therapy based on blocking the ability of these exosomes to fuse with other cells would help stop the spread of drug resistance? (researchers are probably already on it)

  • @jeffkelley5847
    @jeffkelley5847 3 роки тому +7

    The Huggins study only involved two men, one was already castrated. How can you still use this as your basis for treatment.

    • @Dlindo8892
      @Dlindo8892 Рік тому

      Yeah, these doctors are a bunch of clowns!