+Adnan Hussain The reason is that granulocytes themselves can withstand irradiation without a problem, but the lymphocytes in the product are deactivated by irradiation (in the standard doses used in the US). On the other hand, leukoreduction wouldn't make any sense, because you would be removing...the leukocytes! Granulocytes would be filtered out of the product with the other white blood cells.
+BloodBankGuy Sorry didn't get that... granulocytes can be irradiated because they can withstand irradiation without a problem? Thanks for great videos though..!
Dr Joe-- Are the daily meds I take for high blood pressure and cholesterol passed on to and have an effect on the recipient of my donated blood or are these meds also filtered out in processing? Thanks.
you mentioned the cooler temp may not allow white cell to be "formable" to squeeze through filters...does it make a difference if you use a blood warmer?
Nope, because the filtration occurs before the blood GETS to the warmer! In U.S. blood banks, the vast majority of leukocyte reduction occurs at the blood center, so that process is long done before the blood warmer ever contacts the blood product.
![АЛАУДИНОВ у Скабеевой: эти их ВСУ нас НЕ ДОГОНЯТ 😁 [Пародия]](http://i.ytimg.com/vi/an0anqU4WGQ/mqdefault.jpg)
Thanks much. Love using your "casts" in our MLT program
I really learn a lot. Hope you would share the steps of preparation and collection of all blood components and its clinical use. Thank you!
Great video
I think I may have missed it, but it was mentioned that granulocytes can be irradiated but cannot be reduced, why is that?
+Adnan Hussain The reason is that granulocytes themselves can withstand irradiation without a problem, but the lymphocytes in the product are deactivated by irradiation (in the standard doses used in the US). On the other hand, leukoreduction wouldn't make any sense, because you would be removing...the leukocytes! Granulocytes would be filtered out of the product with the other white blood cells.
+BloodBankGuy Sorry didn't get that... granulocytes can be irradiated because they can withstand irradiation without a problem?
Thanks for great videos though..!
Dr Joe-- Are the daily meds I take for high blood pressure and cholesterol passed on to and have an effect on the recipient of my donated blood or are these meds also filtered out in processing? Thanks.
THANKS FOR THIS EDUCATION. GOD BLESS YOU
you mentioned the cooler temp may not allow white cell to be "formable" to squeeze through filters...does it make a difference if you use a blood warmer?
Nope, because the filtration occurs before the blood GETS to the warmer! In U.S. blood banks, the vast majority of leukocyte reduction occurs at the blood center, so that process is long done before the blood warmer ever contacts the blood product.