Fluoroquinolones mode of action

[@HafizahHoshni]

1:40 Doxycline is not an example of FLUROQUINOLONES.
Examples of fluroquinolones are CIPROFLOXACIN, NORFLOXACIN, LEVOFLOXACIN

[@nikunjjoshi5718]

yeah...

[@daimmehmood4079]

doxycyclin is tetracycline lmfao

[@stephanielove4469]

Hafizah Hoshni thank you, the other drug he mentioned is actually a macrolide and not all suffix with cin equals a fluoroquinolone..

[@onlypharmacy]

Subscribe my channel for pharmacy lecture video

[@shivampatel9635]

Thanks so much sir.... even our teacher didn't taught us in so much detail...... Whenever im in a problem...I only go to your videos.... thankyou so much sir

[@windsammisj773]

Excellent ..bravo..Mr. Suman Bhattacharjee. At last all is explained. There are many who would enjoy this you tube on Fluoroquinolones.

[@vangmayireddy9516]

Yeah....Its too good..and easy..too...bcoz of these vedios i can be able to write my examz easily....tq sir.....

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

[@JustinGould72]

Fluoroquinilones (levaquin) have destroyed my life. Thanks for finally explaining to me what actually happened on a cellular level. It's there any way too reverse the damage? My tendons continue to atrophy.

[@JasonHalle]

The first time I took a Fluoroquinolone I soon became suicidal. Since I am usually a very positive person and an optimist even when things are at their worst, I found this frightening and figured it was my body's way of telling me to stop taking the stuff IMMEDIATELY!!! Thanks for sharing Justin Gould.

[@MegaMikeylikes]

Stem Cell infusion into your spine from the stem cells harvested from your own fat cells and grown to provide enough to be inserted into your spine. This is by far the best option it can curb recovery by years as opposed to no treatment.Dr. Ghalili of los angeles regenerative medicine he also suffered and lost the use of his legs for many months. Now he is treating fluoroquinolone toxicity only. Bless You Justin and the best of luck i hope you recover okay.

[@PillWhiteboard]

Amazing video and a way of explanation is spot on , thank you so much

[@manjitrana3608]

I think you got the classification of Topoisomerase wrong (from 12:42 onwards). There are 2 classes of topoisomerase Class- I and Class-II. Class-I cuts one strand of DNA helix (do not require ATP except for reverse gyrase), and Class-II cuts two strands of DNA helix (requires ATP). Examples of Class-I are Topoisomerase I, III, and V. Example of Class-II are Topoisomerases II, IV, and VI.

[@khizkhan3436]

You are best teacher 👍👍

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@kalawatinandan]

Thanks. Good lecture. Correction Doxycycline is not a Fluroquinolone and suffix does not end with cine. Ends with 'xacin'

[@subhradatta354]

Correct dear

[@vangmayireddy9516]

Its a tetracycline derivative

[@ushiikhan7013]

Thanks it was so informative

[@shomusbiologyofficial]

You're welcome

[@snehalchandanshive9863]

Too good
....explaination ..so simple..easy to understand concept

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@rumaanshery6463]

I'm not totally got but i appreciate ur efforts Ser.

[@samixa7]

You explain very well! Thanks..

[@arunasharma3987]

I could learn everything so easily . Appreciate your teaching skills ☺

[@hassanghaffar8986]

😉😉😉😉

[@jyoti2298]

Very helpful vedio thank you so much sir ❤️❤️

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@Susan-dh6dd]

i was floxed in dec 13..trying to fix the destruction levaquin caused..ruined my life..sure wish someone would present a solution..dr lonney herman know how to treat this but he is west palm beach..

[@deepikadarwai2727]

thank you for all the videos..they r awesome. :)

[@purnimadas255]

Excellent explanation

[@shomusbiologyofficial]

Thank you

[@hridyajacob3008]

Useful video

[@shomusbiologyofficial]

You're welcome

[@adnanrahman8326]

If cleaving and ligation done this enzymes what is the function of ligase emzym

[@shomusbiologyofficial]

This is a drug having both features but ligase seals the nick in DNA

[@wisamalsaedi2142]

Ty

[@shomusbiologyofficial]

You're welcome

[@fatimaqueen5372]

best video

[@shomusbiologyofficial]

Thank you

[@thajalongjam4997]

Thank u sir from manipur

[@shomusbiologyofficial]

Thank you

[@drsureshmokamati]

Thank you

[@maheshkannevini349]

Doxycycline is tetracyclines

[@fatimaal-baraki5900]

Thank you very much :)

[@ozzDeveveloperOpenForWork]

so what is fluoroquinolones then? you went into super coiling and i could not connect it to Fluoroquinolones.

[@StudyWithM3E46]

watch the last 3 minutes of it. floroquinolones affect the DNA gyrase and allow them to only carry out the exonuclease activity to make that double stranded break (relieving of supercoiling) but does not retain its Ligation function.

[@ayyanaftab8088]

Bro azithromycine also have cine at the end but belongs to macrolide

[@shomusbiologyofficial]

Yes. There are few exceptions

[@riazsalim3098]

And gemifloxacin

[@soumiaeliane1902]

Thanks very muuuch

[@PapaSM-u6v]

Fluoroquinolones -doxycycline???

[@ssongbird8337]

THIS IS POISEN

[@shwetatiwary9111]

Topoisomerase 2 is dna gyrase

[@subul6942]

Cin not cine

[@basrapharmd3320]

❤️❤️😍

[@shomusbiologyofficial]

You're welcome