Patchwork People
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- Опубліковано 30 вер 2024
- Let's talk of chimeras and mosaics and people.
Transcript here:
freethoughtblo...
Identical twins, one case of Down syndrome: www.latimes.co...
The fusion of two sisters into a single woman suggests that human identity is not in our DNA: english.elpais...
Jeremy Thorpe, Ikeoluwa A. Osei-Owusu, Bracha Erlanger Avigdor, Rossella Tuplerl, Jonathan Pevsner (2020) Mosaicism in Human Health and Disease. Annu. Rev. Genet. 2020. 54:487-510.
Vijg J (2000) Somatic mutations and aging: a re-evaluation. Mutation Research 447: 117-135.
Thompson DJ et al. (2019) Genetic predisposition to mosaic Y chromosome loss in blood. Nature 575:652-657,
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*SHE HAS TWO SOULS!!* (Just wait for it....)
I wish more people would watch things like this. keep puttin' them out there.
I get why science-fiction authors like Neal Stephenson (»Seveneves«) or Scott Sigler (»Nocturnal«) use aspects of epigenetics and chromosomal variation for their stories as a plot device so effectively. It sounds like fiction to most people who didn't get any education beyond flowers, bees, and which sex has which dangly bits.
I love watching PZ debate creationists😂
Very interesting.
Aside from the obvious connotations this has in our modern world - is there a possibility that this sort of thing has a role to play in the extinction - whatever that means - of species throughout history?
????? Are there examples of conjoined twins who are genetically distinct? I thought they were always identical twins that didn't quite fully separate.
This should be required viewing for the gender-fixed-at-conception/birth folks. No, it doesn't address this topic directly and yes, very few will have the scientific chops to grasp much of the argument but the obvious fact of cytological/developmental/environmental (not just genetic) variability contributing to the individual pre and post birth might make some impression.
Interesting stuff. So, quite simply, my DNA is not what I was born with ;) (I know that's being overly simplistic, but it is interesting to see how it shifts and actually changes with age)
😎
17:36 What's the significance, if any, in the increased or stable H4 acetylation at the age of 50 in graph (B)?
I don't know, but H4 acetylation is a precursor to replication. The main point of the figure is that the H4 acetylation becomes discordant in older twins.
Thanks.
I mean don't the mutations in each (or a large percentage of, since conception) of our cells mean we're all a kind of patchwork anyway?
(even if most mutations aren't coding or important)
Yes.
Oh, that's what mosaicism is and the subject of the video =)
The same guy who called his blog the "free thought" but then banned Thunderf00t for simple disagreement
you have no principles