Could you make another video on mammaprint and the hormone blocker? You are the first doctor I’ve found on UA-cam that mentions mammaprint. Mine came back ultra low risk.
I am triple negative breast cancer, stage 2b grade3.... HER2 2+, FISH negative, ER negative. I have had 4cycles of AC that shrunk my tumor from 3cm-1.5c. and 6cycles of Paclotaxol that had no response to the tumor. Will these genotests help me find a chemo that will work.
The average OncotypeDX number is 31. Mine was a 9. Going on six years cancer free. IDC, stage 2A, Estrogen 90% driven, Progesterone 10% driven, HER-2 Negative, Grade 1. BRCA mutation Negative. Took Tamoxifen for a year but had liver enzymes rise so my oncologist took me off. I feel my outcome was a miracle. 💗
I was BRCA2 positive/Invasive ductal carcinoma , there was no treatment other than do nothing because you have your own source, lumpectomy or bilateral mastectomy with reconstruction. When I was 26 I had a total hysterectomy because of being ovarian cancer cells, and so many other female issues to list, and if the genetic coding would of been around back then I could of avoided a lot of things I am going through now.
my mom is 73 yrs old ... did a lumpectomy surgery ... the pathology report says : stage 3a with positive ( er, pr ) negative her2 ... nodal count ( 5/12 ) the oncologists said chemotherapy is a must ... at her age i feel its difficult to take the chemo decision .. my question is : does she qualify for a genomic test ??
Yes anything 3 cm or less is a small tumor. However it’s the definitive pathology that will determine the role of any adjuvant treatment ( chemo, radiation, hormonal or others) and the outcome.
My Oncotype DX score was six. But, my doc only kept me on Arimadex 5 years, even though I suggested longer. It came back in the breast after a mastecomy, in the fat. It's early, and supposedly hasn't spread. I balked at chemo, and that's the only reason he ordered the Oncotype test, but that was 7 years ago. Now it's standard, thanks to a huge study that showed the value of this test.
My Oncotype DX was 6 too. I had cancer on both breasts and had double mastectomy 2 months ago. How did you find the cancer came back? I mean, after a breast was removed and no mammogram on that breast anymore? Congratulations on cancer free for 7 years!
Let's talk about all the risks of tamoxifen including uterine cancer, pulmonary embolism among many other things. The doctors never seems to mention this. And how about secondary malignancies from radiation 15+ years out? Doctors never mention beyond the 5 year mark! I hope women will learn as much as they can before being lured into such "treatments."
@@missdemeanor1092 It’s been shown to have detrimental effects on the heart. As so many women today have heart disease, it is something to think about before proceeding.
@@thinkpositive3084 Yes I have Check 2. My aunts have it too and they have had breast cancer twice. Once had the double mastectomy and lymph nodes removed and it came back in her lymph nodes. The other had a lumpectomy and radiation and it came back in her other breast. CK2 means your chance of recurrence is higher and it also means you have a higher risk of ovarian and colon cancer.
My friend had IDC, Stage 1, Estrogen, Progesterone Positive, HER-2 Negative, Grade 3. OncotypeDX number 19. She had a lumpectomy then refused radiation and meds. She is trying to eat better and reduce acidity. I'm very concerned about her refusing treatment but I'm not Dr. Yvonne & it wasn't my place to push treatment.
@@agnesmatheus6585 not always. My aunt was stage 1A Er/PR positive HER2- grade 2 had the mastectomy and chemo and declined hormone therapy and it returned stage IV 18 months later. It’s not always good to give people advice on breast cancer Treatments because every cancer and every person is different and each journey can vary. What will work for you could be a death sentence for another. Take it from someone who watched her aunt die and then get diagnosed herself at the same age with the same cancer but our journey was totally different and you have to have trust in your medical team and if you don’t, find one that you do.
@@CrystalVIsMedid your aunt have genomic testing after surgery and genetic testing before surgery? I had mammaprint on my tumor post surgery and mine showed ultra low risk. National Institute of Health shows 99.7% 5-10 year survival rate without adjuvant therapy. I also had genetic testing before surgery and was normal. I had same initial diagnosis as your aunt. I am having radiation for any microscopic cells that aren’t yet detectable but testing shows chemo is not advisable for me.
They all are similar, genomic tests that is. I highlight on our website the most commonly used tests in the US here. Same video, but great information and links below the video. www.breastcancercourse.org/genomic-testing/
Could you make another video on mammaprint and the hormone blocker? You are the first doctor I’ve found on UA-cam that mentions mammaprint. Mine came back ultra low risk.
I am triple negative breast cancer, stage 2b grade3.... HER2 2+, FISH negative, ER negative. I have had 4cycles of AC that shrunk my tumor from 3cm-1.5c. and 6cycles of Paclotaxol that had no response to the tumor. Will these genotests help me find a chemo that will work.
How are you doing now, Chanthelle? Hoping you are looking at this all behind you.
The average OncotypeDX number is 31. Mine was a 9. Going on six years cancer free. IDC, stage 2A, Estrogen 90% driven, Progesterone 10% driven, HER-2 Negative, Grade 1. BRCA mutation Negative. Took Tamoxifen for a year but had liver enzymes rise so my oncologist took me off. I feel my outcome was a miracle. 💗
wow. Congratulations.
Congratulations
Wioo
Congratulations
Congratulations
The background music is irritating so much so that it hard to listen your voice
I was BRCA2 positive/Invasive ductal carcinoma , there was no treatment other than do nothing because you have your own source, lumpectomy or bilateral mastectomy with reconstruction. When I was 26 I had a total hysterectomy because of being ovarian cancer cells, and so many other female issues to list, and if the genetic coding would of been around back then I could of avoided a lot of things I am going through now.
my mom is 73 yrs old ... did a lumpectomy surgery ... the pathology report says : stage 3a with positive ( er, pr ) negative her2 ... nodal count ( 5/12 ) the oncologists said chemotherapy is a must ... at her age i feel its difficult to take the chemo decision .. my question is : does she qualify for a genomic test ??
I think its pretty standard now, but push for it.
I took prepro to hinder the effects of the change of life which was later found to have caused the breast cancer "Prempro
Hi Doctor, What do you mean by small tumor. My tumor is 3cm. Is that considered small
Yes anything 3 cm or less is a small tumor. However it’s the definitive pathology that will determine the role of any adjuvant treatment ( chemo, radiation, hormonal or others) and the outcome.
My Oncotype DX score was six. But, my doc only kept me on Arimadex 5 years, even though I suggested longer. It came back in the breast after a mastecomy, in the fat. It's early, and supposedly hasn't spread. I balked at chemo, and that's the only reason he ordered the Oncotype test, but that was 7 years ago. Now it's standard, thanks to a huge study that showed the value of this test.
My Oncotype DX was 6 too. I had cancer on both breasts and had double mastectomy 2 months ago. How did you find the cancer came back? I mean, after a breast was removed and no mammogram on that breast anymore? Congratulations on cancer free for 7 years!
My onco DX results were a "7" of recurring I did have it in the 2nd breaat 5 years later the results spared me from chemo I wa so wvwe greatful
Let's talk about all the risks of tamoxifen including uterine cancer, pulmonary embolism among many other things. The doctors never seems to mention this. And how about secondary malignancies from radiation 15+ years out? Doctors never mention beyond the 5 year mark! I hope women will learn as much as they can before being lured into such "treatments."
Does radiation put you at risk for other cancers?
@@missdemeanor1092 It’s been shown to have detrimental effects on the heart. As so many women today have heart disease, it is something to think about before proceeding.
Lisa Martin. When you get diagnosed with breast cancer, then you can come back and comment:) Until then, you’re opinion is not helpful.
Chemo and radiotherapy comes with risk but with cancer the benefit outweighs the risk
@@aremedyproject9569 I have Stage 1 IDC
Ur lecture is very good but needs markings to be more clear
I have had Nebula Genomics testing done. Is it a good one?
Why aren't you talking about the Chek 2 gene mutation?
Hi, do you have check 2?
@@thinkpositive3084 Yes I have Check 2. My aunts have it too and they have had breast cancer twice. Once had the double mastectomy and lymph nodes removed and it came back in her lymph nodes. The other had a lumpectomy and radiation and it came back in her other breast. CK2 means your chance of recurrence is higher and it also means you have a higher risk of ovarian and colon cancer.
Thousands of years?!?!😳😳😳
In my country oncologists give all patients chemo, radiation and other therapies based on ER PR HER2 results.
I would love to see an episode on the Signatera type tests. Tests for residual cancer dna cells
My friend had IDC, Stage 1, Estrogen, Progesterone Positive, HER-2 Negative, Grade 3. OncotypeDX number 19. She had a lumpectomy then refused radiation and meds. She is trying to eat better and reduce acidity. I'm very concerned about her refusing treatment but I'm not Dr. Yvonne & it wasn't my place to push treatment.
She made the right choice I chosed the same choice as well, don't worry will be fine
@@agnesmatheus6585 not always.
My aunt was stage 1A Er/PR positive HER2- grade 2 had the mastectomy and chemo and declined hormone therapy and it returned stage IV 18 months later. It’s not always good to give people advice on breast cancer
Treatments because every cancer and every person is different and each journey can vary. What will work for you could be a death sentence for another.
Take it from someone who watched her aunt die and then get diagnosed herself at the same age with the same cancer but our journey was totally different and you have to have trust in your medical team and if you don’t, find one that you do.
@@CrystalVIsMe Wow Crystal!!! Thanks for the comments. I’m sorry you lost your aunt. I hope you are doing well. I’m at the beginning of my journey.
@@CrystalVIsMedid your aunt have genomic testing after surgery and genetic testing before surgery? I had mammaprint on my tumor post surgery and mine showed ultra low risk. National Institute of Health shows 99.7% 5-10 year survival rate without adjuvant therapy. I also had genetic testing before surgery and was normal. I had same initial diagnosis as your aunt. I am having radiation for any microscopic cells that aren’t yet detectable but testing shows chemo is not advisable for me.
Hello Dr.John,Thank you very much for this information. please suggest how do you look at Prosigna test in terms of giving results?
They all are similar, genomic tests that is. I highlight on our website the most commonly used tests in the US here. Same video, but great information and links below the video. www.breastcancercourse.org/genomic-testing/
Thank you very much for your reply. really appreciate it.