Mendelian Disorders| Neet| 1st grade| Csir Net| Set| Gate XL| Assistant Professor| RPSC Exam|

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Mendelian disorders are genetic conditions that occur when a single gene is mutated. They are also known as monogenic diseases.
How do they occur?
Gregor Mendel's studies of pea plants in the 19th century established the patterns of inheritance for Mendelian disorders.
Mutations in a gene on an autosome or sex chromosome cause Mendelian disorders.
The type of disorder (dominant, recessive, or X-linked) depends on the mutated gene.
How are they inherited?
Mendelian disorders can be inherited in families.
Pedigree analysis of large families can help determine if a gene is dominant or recessive, and if it's located on an autosome or sex chromosome.
What are some examples?
Sickle cell anemia, Thalassemia, Cystic fibrosis, Hemophilia, Huntington's disease, and Phenylketonuria.
Mendelian disorder is a type of genetic disorder that affects humans that is caused primarily by mutations in a single gene or as a result of structural abnormalities in the genome.
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