Hey man thank for explaining the words you use, cant stand some people who will say a sentence for you with words you obviously dont know, then tell you they will explain those words at a later date. SHT tears up my learning potential because i WANT to know what the word is but instead they sit and let me ponder on it.
sir plz explain the action potential of smooth muscle like spike potential ,spike potenial intitiated by slow wave rhythm and action potenial with platue phase
These topics are basically looking at how action potentials in smooth muscle cells differ from action potentials in skeletal muscle cells (so I am assuming you know what action potentials are). Most smooth muscle cells do not have sodium channels. They have two kinds of calcium (Ca++) channels involved in action potentials. One type called "ligand gated Ca++ channels" open in response to neurotransmitters or certain hormones. The other type of Ca++ channel in smooth muscle membranes are "voltage gated Ca++ channels." When a smooth muscle cell undergoes action potential in response to hormone or neurotransmitter it happens in these basic steps... 1. The first type of channel (ligand gated) is stimulated by neurotransmitter or hormone and Ca++ enters the cell, causing the inside of the cell to become more positive. 2. Once the inside of the cell becomes positive enough the voltage gated Ca++ channels open and this causes the spike (so that is spike potential) the membrane quickly becomes very positive on the inside. 3. Slow voltage gated potassium (K+) channels then bring the membrane back towards resting potential (more negative on the inside) by allowing K+ to leave the cell. Slow wave rhythm: Some smooth muscle cells have channels that cause the membrane to continuously become more positive on the inside until the voltage gated Ca++ channels are activated and an action potential spike is observed. So, these cells activate themselves in a rhythmic manor. After each action potential they return to being negative on the inside and the cycle repeats. These cells are "auto rhythmic" For plateau phase... in some smooth muscle cells the calcium channels stay open longer, so the action potential displays a rounded or flattened top (stays positive longer)... that's the plateau. I hope this helps :)
These lectures HELP..... Thank you!
You sir, can surely explain complex things so kudos to you. Thanks a bunch!
Hey man thank for explaining the words you use, cant stand some people who will say a sentence for you with words you obviously dont know, then tell you they will explain those words at a later date. SHT tears up my learning potential because i WANT to know what the word is but instead they sit and let me ponder on it.
hi,
super good,am a medical student however i appreciate your lectures.
they are pretty good.
be blessed.
Now I can move on to the next part.....Very very helpful. Thank you
thanx for spreading knowledge free in world of selfishness ....ur lectures r very helpful..i consider u as my teacher sir..thax again :)
Thank you, you have made this simpler for me. Bless you!
Sir, Thank you for making these videos for us, this was very useful video as well as all the others.
Thank you so much......this was very helpful to me.
Thank you! Your lecture really helps.
superb...amazing
sir thanks a lot. your teaching style is far ood than my teachers. sir I am requesting you to take a class on brain. I only have vague out it
sir plz explain the action potential of smooth muscle like spike potential ,spike potenial intitiated by slow wave rhythm and action potenial with platue phase
These topics are basically looking at how action potentials in smooth muscle cells differ from action potentials in skeletal muscle cells (so I am assuming you know what action potentials are). Most smooth muscle cells do not have sodium channels. They have two kinds of calcium (Ca++) channels involved in action potentials. One type called "ligand gated Ca++ channels" open in response to neurotransmitters or certain hormones. The other type of Ca++ channel in smooth muscle membranes are "voltage gated Ca++ channels." When a smooth muscle cell undergoes action potential in response to hormone or neurotransmitter it happens in these basic steps...
1. The first type of channel (ligand gated) is stimulated by neurotransmitter or hormone and Ca++ enters the cell, causing the inside of the cell to become more positive.
2. Once the inside of the cell becomes positive enough the voltage gated Ca++ channels open and this causes the spike (so that is spike potential) the membrane quickly becomes very positive on the inside.
3. Slow voltage gated potassium (K+) channels then bring the membrane back towards resting potential (more negative on the inside) by allowing K+ to leave the cell.
Slow wave rhythm: Some smooth muscle cells have channels that cause the membrane to continuously become more positive on the inside until the voltage gated Ca++ channels are activated and an action potential spike is observed. So, these cells activate themselves in a rhythmic manor. After each action potential they return to being negative on the inside and the cycle repeats. These cells are "auto rhythmic"
For plateau phase... in some smooth muscle cells the calcium channels stay open longer, so the action potential displays a rounded or flattened top (stays positive longer)... that's the plateau.
I hope this helps :)
super easy explanation!! great !!
extremely helpful.
thank you so much
spike and over shout really confusd me i searched ur video for action potential in smooth muscle but i ddnt find it.
Thank u sir u made it so easy
perfect... its all starting to click :)
hi
Awful video... Just kidding! Wish I would have watched before the review today! Super helpful!