Perform docking ONLINE in 5 MINUTES |CB-Dock |Cavity-detection Blind Docking |Easiest & best docking

In this tutorial online server CB-Dock has been used to perform docking. you can easily perform docking in just 5 minutes. NO prior knowledge of programming is required. The molecular docking approach can be used to investigate interaction between a small molecule and a protein. Molecular docking is one of the most frequently used methods in structure-based drug design, due to its ability to predict the binding-conformation of small molecule ligands to the appropriate target binding site. Characterisation of the binding behaviour plays an important role in rational design of drugs as well as to elucidate fundamental biochemical processes.
#Docking #MolecularDocking #ProteinDocking #DrugDesigning # Protein-ligand docking
#Drug Discovery #Structure based Virtual Screening #Docking #ADME/T #DNA docking #drug #Virtual screening, ## Computer aided drug discovery.
• Structure-Based Drug D...
• Analysis of Docking re...
• Protein-Ligand Docking...

[@mdataulislam496]

Good to see you to help the scientific community.

[@MuzzammelRehman]

Thank you sir.

[@syedrizwanshah3935]

Thanks a lot for making this difficult task easy for me & everyone.

[@MuzzammelRehman]

Thank you

[@kashafaltaf3462]

Asalamu Alaikum sir, Your lectures and tutorials are amazing. i request you to make a separate tutorial on pharmacophore modeling using any online platform or any other tool which is free /trial licensed like ligandscout.

[@MuhammadFaizan-mi9yo]

Appreciate sir. kindly make the next video on the IEBD database for epitope detection and all its aspects.

[@inayatsaidi3872]

Thank you very much sir. God bless you

[@MuzzammelRehman]

Thank you

[@cappamaampi2452]

Think you for this good presentation

[@MuzzammelRehman]

So nice of you

[@susmitasahoo3743]

This helped a lot in my thesis work. Thanks a lot. Please make a video on how to use to patchdock and firedock server.

[@navgeetsandhu7029]

Thankyou so much sir. Docking seems so easy

[@MuzzammelRehman]

You are most welcome

[@rahulnaga5010]

That's a very nice presentation...sir can you please suggest me how it will use as a standalone...

[@greyfield6828]

Brilliant presentation. thanks\

[@MuzzammelRehman]

Thank you dear and also share with others to promote free education

[@fizachaudhary7049]

fantastic

[@MuzzammelRehman]

Thank you

[@prabirmondal8541]

Dear sir, how analysing the figure obtained from cd dock... Please give a supporting lecture ( video)..... Thank you

[@ogunoluwamayowa4749]

Great content as usual. Thank you. I have a question, do you think online docking is acceptable in International journals?

[@MuzzammelRehman]

Yes you can publish after validation

[@vincentbeltran8267]

@@MuzzammelRehman How to do validation?

[@elhadadsalaheddine6797]

Hello professor , thank you so much for you explanation, i wanna ask you if the pdb file of the complexe generated with cb dock can be submitted to MD simulation without any problems?

[@mohsinshad9844]

Which is the best software / tool among all the docking software.

[@fereshtehazimian8044]

Thank for presentation. I just wanted to ask a problem. When iam using this docking program, it couldn't able to recognize my ligand. Can you give me suggestion?
Thanks

[@soumitrashome1642]

Thank you for the information. My receptor for analysis is greater than 3 MB and the server is not uploading it. Can you please suggest how to overcome this issue?

[@emanmaherabdelhamidmostafa6560]

Plz, what is the difference between autodock and cbdock? Are they the same using?

[@shamalasham102]

For the CB dock, it is necessary to perform energy minimization for ligand molecules before uploading the file.

[@MuzzammelRehman]

No

[@shamalasham102]

sir, can we use this CB docking for paper publication?

[@MuzzammelRehman]

@@shamalasham102 yes

[@shamalasham102]

thank you sir

[@vincentbeltran8267]

Can I dock on any protein even if it is not a receptor?

[@juniorkidscorner]

Sir how can we know which ligand should we use?

[@vincentbeltran8267]

How to dock if the pdb file that is only available for the protein is in complex with a ligand? Do I need to remove that ligand from the structure before inputting it to CB-DOCK? If that is how it is done, how to do it?

[@7-zoolmen7a11]

How can we assess whether the link between a protein and a ligand is strong or not?

[@MuzzammelRehman]

For this you can perform Molecular Dynamics Simulation

[@sanjeev1227]

May I know the protein for finding antianginal activity pls help sir

[@vincentbeltran8267]

It seems like that the protein file size limit for CB-DOCK is only 3 MB. My protein is 4.5 MB. Do you know any pdb file size compressor?

[@huzaifarana4532]

How many ligands can be docked in cb dock?

[@kashafaltaf3462]

Asalamu alium sir , want to now the best best latest chemical database to screen out the best leads? As I remember you have deliver one lecturer on it. please send me the details. than you

[@MuzzammelRehman]

You can use ZINC, Chemble , MCule, NCI , Asinex etc

[@kashafaltaf3462]

actually I forget that one .

[@MuzzammelRehman]

Ok

[@jddc9728]

Can i use this cb-dock as a basis for my grid sizes in autodock vina?

[@farzadmolani7435]

Hi. How can someone get RMSD per each pose?

[@anushaupadhye5624]

Sir o ligang ka size kam chaiye Aisa bol raha hai us ligand file kon kaise Kam kre

[@laibagull7883]

Jab ligand ka size bra ho ?