Rh antigen explained

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  • Опубліковано 27 сер 2024
  • Hi! Welcome to Blood Talks!
    Rh antigen is important in transfusion medicine. Knowing how to read and write in both Fisher-Race and Wiener terminology is importance in communication amount blood bankers.
    Correction
    1:31 It is Rh antibody not Rh antigen
    6:00 and 9:00 Rh negative patient with E antigen and no c antigen.
    Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
    Note: the patient can be both c and C negative; however, it is less common.
    Sorry about that guys
    Timestamps:
    0:07 - Video overview
    0:49 - Rh antigen overview
    2:45 - Rh terminology
    3:21 - Fisher - Race terminology
    4:48 - Examples: Fisher - Race terminology
    6:38 - Wiener terminology
    4:47 - Examples: Wiener terminology
    9:21 - History of Rh antigen
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    #FisherRaceTerminology
    #WienerTerminology
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    #WienerMethod
    #RhAntigensHistory
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    #BloodBank
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КОМЕНТАРІ • 43

  • @BloodTalks
    @BloodTalks  2 роки тому +6

    1:31 It is Rh antibody not Rh antigen
    6:00 and 9:00 Rh negative patient with E antigen and no c antigen.
    Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
    Note: the patient can be both c and C negative; however, it is less common.
    Sorry about that guys

  • @Arlyyp1684
    @Arlyyp1684 21 день тому

    This VDO help me a lot Thank you!!!😭💖💖

  • @claudinejeanabenojar4897
    @claudinejeanabenojar4897 2 роки тому +10

    In 6:00 it should be d C E. Because the missing is small c antigen. Remember that small c is also expressed in the rbc. So it should be d C E

    • @BloodTalks
      @BloodTalks  2 роки тому +6

      Hi Jean Claude! You are absolutely correct. I make a mistake. I apologized for that and thank you for pointing that out. I hope whoever watch this in the future see the blur and come down to read this comment.
      Rh negative patient with E antigen and no c antigen.
      Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
      Note: the patient can be both c and C negative; however, it is less common.

  • @saeedm.aldosari9389
    @saeedm.aldosari9389 Рік тому +1

    you are the only one who explained the Rh system simply and made me understand it easily. Thank you so much, especially for the rules they were very helpful.

  • @kintex6441
    @kintex6441 2 роки тому +7

    Might be wrong here, but I thought c and C, along with E and e, are different antigens. From what I remember, lowercase only represents absence on d, and instead signify a different antigen on c and e.

    • @BloodTalks
      @BloodTalks  2 роки тому +3

      You are not wrong. I know it may be confusing at times. There are genotype and phenotype. The genotype is what pair the we got from one from mother and another from father. Phenotype is what express. The gene C, c, E, e make antigens that can express on the RBC.

  • @KanyesigyeGeofrey
    @KanyesigyeGeofrey 4 місяці тому +1

    Thank you so much for the summary

    • @BloodTalks
      @BloodTalks  4 місяці тому +1

      Glad it was helpful!

  • @benkay3466
    @benkay3466 8 місяців тому +1

    Thanks so much for clear explanation of this topic.

    • @BloodTalks
      @BloodTalks  7 місяців тому

      Glad it was helpful!

  • @rabiazubair3706
    @rabiazubair3706 Рік тому +1

    This is v v simple video and explained best in a short time . Thanks alot

    • @BloodTalks
      @BloodTalks  Рік тому +1

      Thank you. You just made my day.

  • @fahmidasiyad6971
    @fahmidasiyad6971 3 місяці тому +1

    Very useful..... thanks ma'am

  • @sanjaykumar-ew6mb
    @sanjaykumar-ew6mb 11 місяців тому +1

    I really ❤ your videos your presentation is always awesome in your sweet voice maram

    • @BloodTalks
      @BloodTalks  10 місяців тому +1

      Thank you so much 😀

  • @swazimukunta5336
    @swazimukunta5336 2 місяці тому +1

    Thank you 😭😭😭😭

  • @safesoundequine8511
    @safesoundequine8511 2 роки тому +1

    love your videos - could you do more ABO discrepancy problems?

    • @BloodTalks
      @BloodTalks  2 роки тому +1

      I will try. Is there any kind in particular that you want to see?

  • @amyappenteng88
    @amyappenteng88 Місяць тому +1

    Can you please help me, I am O RhD positive and produce Anti-E, how does this occur?

    • @BloodTalks
      @BloodTalks  Місяць тому +2

      Thank you for your question.
      Your blood type has nothing to do with you having anti-E or not. The ABO blood group is different from the Rh blood group.
      E is part of the Rh blood group. Since E is not a naturally occurring antibody, you had to be exposed to it in the past.
      There are a couple of ways you can exposed to E antigens such as blood transfusion, pregnancy if you are a female, or needle sharing.

  • @juliannapowell6791
    @juliannapowell6791 2 роки тому +1

    Love your videos

  • @Tcastolo
    @Tcastolo Рік тому +1

    What if the patient has lil c antigen, how do we express it ?

    • @BloodTalks
      @BloodTalks  Місяць тому +1

      you write c, e.g. dce, Dce, DcE, dcE

  • @asmaabdirisak1497
    @asmaabdirisak1497 7 місяців тому +1

    thank u so much love u sister

  • @jheanayjoven5121
    @jheanayjoven5121 Рік тому +1

    Can i ask what do you mean by blood type B Rh+??

    • @BloodTalks
      @BloodTalks  Рік тому +2

      B is the blood type and the Rh+ an antigen on the RBC. The present of the antigen generally represent as positive and the absence of the antigen generally represent as negative.

  • @cwynt9319
    @cwynt9319 2 роки тому

    Lovely video but the table @7:43 has R0 to r''. Shouldn't it be just r. Also where R1 is, shouldn't it be r' across from it and R2 should have r'' parallel? Please clarify. Thanks alot

    • @BloodTalks
      @BloodTalks  2 роки тому +1

      @ C Wynt
      You are correct if you do a direct translation from Rh positive to Rh negative. Now that you have point it out, I can see how it could be confusion. I'm sorry about that. The table was just to show the different way you can write using Wiener Terminology when you have Rh positive or Rh negative patient.
      Please refer to this www.labce.com/spg1463242_fisher_race_and_wiener_terminology_road_map.aspx

  • @naluh_n
    @naluh_n 2 роки тому +1

    great video

  • @dr.zainabshahid7736
    @dr.zainabshahid7736 8 місяців тому +1

    Nice .. please guide me to clear DHA exam

    • @BloodTalks
      @BloodTalks  7 місяців тому

      What is a DHA exam?

    • @dr.zainabshahid7736
      @dr.zainabshahid7736 7 місяців тому

      @@BloodTalks it's Dubai heath authority test for medical laboratory scientist

  • @briannguch
    @briannguch 2 роки тому +1

    well understood very helpfull

    • @BloodTalks
      @BloodTalks  2 роки тому

      Thank you. You make my day. Enjoy!

  • @kanailaldolai9386
    @kanailaldolai9386 Рік тому +1

    Bombay blood group have rh antigen

    • @BloodTalks
      @BloodTalks  Місяць тому +1

      First, let’s look at the definition of Bombay. Bombay blood group people are those who lack the H antigen. H antigen is a building block for A and B sugar to attach. Bombay blood group is described as the patient whose ABO blood type cannot be determined using anti-A or anti-B reagents due to the lack of H antigen. The H antibody interferes with antibody screens and crossmatches for this type of patient.
      The ABO antigen is different from the Rh antigen. The Rh blood group is different. The Rh antigen is represented by a different set of genes. The presence or absence of D, C, E, or c, e antigen is independent of the h antigen.
      The ABO blood group and the Rh blood group are RBC antigens but they are coded on different genes.