Rh antigen explained
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- Опубліковано 27 сер 2024
- Hi! Welcome to Blood Talks!
Rh antigen is important in transfusion medicine. Knowing how to read and write in both Fisher-Race and Wiener terminology is importance in communication amount blood bankers.
Correction
1:31 It is Rh antibody not Rh antigen
6:00 and 9:00 Rh negative patient with E antigen and no c antigen.
Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
Note: the patient can be both c and C negative; however, it is less common.
Sorry about that guys
Timestamps:
0:07 - Video overview
0:49 - Rh antigen overview
2:45 - Rh terminology
3:21 - Fisher - Race terminology
4:48 - Examples: Fisher - Race terminology
6:38 - Wiener terminology
4:47 - Examples: Wiener terminology
9:21 - History of Rh antigen
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1:31 It is Rh antibody not Rh antigen
6:00 and 9:00 Rh negative patient with E antigen and no c antigen.
Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
Note: the patient can be both c and C negative; however, it is less common.
Sorry about that guys
This VDO help me a lot Thank you!!!😭💖💖
In 6:00 it should be d C E. Because the missing is small c antigen. Remember that small c is also expressed in the rbc. So it should be d C E
Hi Jean Claude! You are absolutely correct. I make a mistake. I apologized for that and thank you for pointing that out. I hope whoever watch this in the future see the blur and come down to read this comment.
Rh negative patient with E antigen and no c antigen.
Since, this patient has no c antigen the patient is most likely to express C on the RBC. In another word this patient is Rh negative with E antigen and C antigen. This translates into dCE in Fisher-Race or r^y in Weiner terminology.
Note: the patient can be both c and C negative; however, it is less common.
you are the only one who explained the Rh system simply and made me understand it easily. Thank you so much, especially for the rules they were very helpful.
Thank you. 👍
Might be wrong here, but I thought c and C, along with E and e, are different antigens. From what I remember, lowercase only represents absence on d, and instead signify a different antigen on c and e.
You are not wrong. I know it may be confusing at times. There are genotype and phenotype. The genotype is what pair the we got from one from mother and another from father. Phenotype is what express. The gene C, c, E, e make antigens that can express on the RBC.
Thank you so much for the summary
Glad it was helpful!
Thanks so much for clear explanation of this topic.
Glad it was helpful!
This is v v simple video and explained best in a short time . Thanks alot
Thank you. You just made my day.
Very useful..... thanks ma'am
Welcome 😊
I really ❤ your videos your presentation is always awesome in your sweet voice maram
Thank you so much 😀
Thank you 😭😭😭😭
Thank you. 😊
love your videos - could you do more ABO discrepancy problems?
I will try. Is there any kind in particular that you want to see?
Can you please help me, I am O RhD positive and produce Anti-E, how does this occur?
Thank you for your question.
Your blood type has nothing to do with you having anti-E or not. The ABO blood group is different from the Rh blood group.
E is part of the Rh blood group. Since E is not a naturally occurring antibody, you had to be exposed to it in the past.
There are a couple of ways you can exposed to E antigens such as blood transfusion, pregnancy if you are a female, or needle sharing.
Love your videos
Thank you.
What if the patient has lil c antigen, how do we express it ?
you write c, e.g. dce, Dce, DcE, dcE
thank u so much love u sister
Most welcome 😊
Can i ask what do you mean by blood type B Rh+??
B is the blood type and the Rh+ an antigen on the RBC. The present of the antigen generally represent as positive and the absence of the antigen generally represent as negative.
Lovely video but the table @7:43 has R0 to r''. Shouldn't it be just r. Also where R1 is, shouldn't it be r' across from it and R2 should have r'' parallel? Please clarify. Thanks alot
@ C Wynt
You are correct if you do a direct translation from Rh positive to Rh negative. Now that you have point it out, I can see how it could be confusion. I'm sorry about that. The table was just to show the different way you can write using Wiener Terminology when you have Rh positive or Rh negative patient.
Please refer to this www.labce.com/spg1463242_fisher_race_and_wiener_terminology_road_map.aspx
great video
Thank you
Nice .. please guide me to clear DHA exam
What is a DHA exam?
@@BloodTalks it's Dubai heath authority test for medical laboratory scientist
well understood very helpfull
Thank you. You make my day. Enjoy!
Bombay blood group have rh antigen
First, let’s look at the definition of Bombay. Bombay blood group people are those who lack the H antigen. H antigen is a building block for A and B sugar to attach. Bombay blood group is described as the patient whose ABO blood type cannot be determined using anti-A or anti-B reagents due to the lack of H antigen. The H antibody interferes with antibody screens and crossmatches for this type of patient.
The ABO antigen is different from the Rh antigen. The Rh blood group is different. The Rh antigen is represented by a different set of genes. The presence or absence of D, C, E, or c, e antigen is independent of the h antigen.
The ABO blood group and the Rh blood group are RBC antigens but they are coded on different genes.