All of your videos are excellent!!! I am amazed that how one person can explain such diverse topics in so lucid manner....really I have to appreciate the excellent job
I don't understand, you said proteins can't flip flop but they can rotate from one leaflet to the other. what is the difference? the picture you drew shows a flip flop, is this not misleading if they can't do this?
I think asymmetry is caused when vesicles containing that consist of a lipid bilayer are transported from Golgi apparatus to the membrane. The vesicle itself contains asymetric distribution of phospholipids and when the vesicle fuses with the membrane the asymmetry is also imprinted on to the membrane. In addition membrane proteins like flippase and floppase (Yes that is their actual name) will move phospholipids against their concentration gradient to maintain asymetry (I imagine they use ATP). So I think asymetry came first and is maintained by membrane protein. What is also interesting to note is that red blood cells will eventually lose asymetry overtime. Some lipids in the membrane with a net negative charge can end up in the outerleaflet, this signals macrophages to target the aged blood cell.
Your explanations are absolutely brilliant
All of your videos are excellent!!! I am amazed that how one person can explain such diverse topics in so lucid manner....really I have to appreciate the excellent job
These lectures are so amazing. THANK YOU!! Please keep making more for Biochem 2! :)
you're better than my professors
amazing...i think i cn completely rely on ur channel for conceptual part...thanku so much for ur untiring efforts...love frm India
thanks a lot ..for the amazing explanation
Algun estudiante de la IUPI tratando de salvar el semestre? Awesome vid man Thank you sooo much
I don't understand, you said proteins can't flip flop but they can rotate from one leaflet to the other. what is the difference? the picture you drew shows a flip flop, is this not misleading if they can't do this?
He also said they can not rotate
Ur lectures arr really helpful
Great explanation👏🏻👏🏻
How does animal cell take advantage of asymmetry of the phospholipid bilayer?
soo good 🥺 Thank You teacher
LOVE YOUR SHIRT BRO
From where is this lecture was being given❤
The sodium potassium pump doesn't work with ATP, it is a secondary form of active transport
Oh yes it does. You just said it yourself.. Active transport = ATP
+AK LECTURES (Andrey K) I think she meant directly working with ATP. But great video, very clear! :)
so what came first...the membrane or the asymmetry? ;) thank you! you cleared up my grad school lecture in 20 minutes...
I think asymmetry is caused when vesicles containing that consist of a lipid bilayer are transported from Golgi apparatus to the membrane.
The vesicle itself contains asymetric distribution of phospholipids and when the vesicle fuses with the membrane the asymmetry is also imprinted on to the membrane. In addition membrane proteins like flippase and floppase (Yes that is their actual name) will move phospholipids against their concentration gradient to maintain asymetry (I imagine they use ATP).
So I think asymetry came first and is maintained by membrane protein.
What is also interesting to note is that red blood cells will eventually lose asymetry overtime. Some lipids in the membrane with a net negative charge can end up in the outerleaflet, this signals macrophages to target the aged blood cell.
@@theamazingguy150 Interesting theory. Though, Scramblase has an even better name than flippase or floppase.
You are amazing
amazing explanation
thankz for tiring your voice for us🌹😄
Love u sir
thank you so much!
can you help me, I couldn't understand what are the two mechanisms for generating the asymmetry in the lipid bilayer?
Dude, just read if you can't listen!
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