A New Hope in Type 1 Diabetes Research | 2024 | TCOYD Virtual Diabetes Conference
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- Опубліковано 8 лют 2025
- Cutting-edge Type 1 Diabetes (T1D) research explained! Dr. Pettus reveals game-changing developments in 2024, which you should know!
🆕 Teplizumab (Tzield): FDA-approved drug delaying T1D onset
🧬 Stem cell therapies & gene editing for beta cell replacement
💉 Islet cell transplants without immunosuppression
🧪 Clinical trials for newly diagnosed Type 1 Diabetes patients
⏱️ In this video Dr. Perttus dive into:
1. T1D Explained: Autoimmune Process
2. New T1D Staging System
3. Teplizumab for T1D Prevention
4. Preserving Beta Cells in New Onset T1D
5. Beta Cell Replacement Strategies
6. Gene Therapy for Insulin Production
7. How to Join Clinical Trials
🔑 Takeaways:
T1D risk screening
C-peptide's role in type 1 diabetes management
Vertex Pharmaceuticals' stem cell breakthroughs
GKAA's innovative gene therapy approach
👨⚕️ Dr. Pettus shares insider insights on groundbreaking research and how YOU can get involved in shaping the future of T1D treatment!
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Wow! I feel like we actually are close to a cure. I've had t1 since 1987, and I was 6. It's so hard, and it would be so nice to just be able to eat something without worrying about blood sugar.
We are hopeful as well! We just have to pushing forward towards more advancements and progress!
Thanks a lot for this information. Always great content very well presented.
Thanks - appreciate it!
Great update. Thumbs up if you recall the days when docs would say, "a cure is just around the corner...". So glad for the research and Internet to exchange information. Certainly a boost to science with easier access to bypass $2000 journal subscriptions and 10-cent library photocopies.
Haha! That's true!
Thank you for the updates!! The muscle gene one sounds amazing if they can pull it off!
Lots of interesting research on potential new therapies...we're excited to see where they go!
Thank you for updating us with the information! The annual TCOYD One Conferences are a good place for a research company to set up a booth, offer info. and, recruit participants for this and other studies. Sounds exciting!
You are so right, Karen! :)
Thank you. So promising, especially some of those timelines 🙏
Agreed! 🤞
Maybe make a uppdate note with the new Sana discovery with "Stelth cells" with no need to imunocupressions.
What is the name of the company that you mentioned doing gene modified islet cell injections in the leg? I haven’t heard of them.
By the way, Sana Biotechnology, out of Seattle, is about to run a similar trial injecting gene modified cells in the forearm of human patients. It’s going to take place at Uppsala University Hospital in Sweden before year end with results likely very soon!
Thanks for the info! The company you're asking about is called Kriya Therapeutics. Here's their website: kriyatherapeutics.com/
It’s very unfortunate that a large chunk of the T1D population is too young for prevention or preservation treatment during new onset.
From Dr. E: "From what I gather, most of the studies exclude people younger than 8 and over 65. Tzield is for those 8 years old and above, but new studies are happening all the time."
Whats the name of the injectable virus company? Greecrea?
It's Kriya for anyone wondering
I was here to ask the same thing. Sana Biotechnology is about to do the same thing in humans in a trial scheduled by year end. Exciting stuff!
What is your explanation for a 4 year old girl who has a good percentage of beta cells and a negative antibody test, but her sugar rises after eating... reaches high numbers. Some doctors say she has type 1, and some say she has moderate diabetes, but it is normal in the morning!!!! Before breakfast I no longer trust doctors here. No one knows the reason.
Interesting question. Here is Dr. Edelman's reply: "Certainly I don't have all the information, but she may have MODY - mature onset diabetes of the young. Look it up online. There are 14 types. There are genetic tests to determine if she does have it or not."
@@TCOYDtvHello Doctor, I am glad for the response. Her fasting blood sugar is between 50 to 90, but it rises after dinner only, reaching 400, then goes back down in the morning (without any medication or insulin). However, because we did not do a genetic analysis, the doctor gave her insulin, even though the pH result was excellent and there were no symptoms of DKA. We refused, but the doctor insisted on insulin, which caused her a condition called refeeding syndrome. She is fine now and has come out of this dangerous condition, but what about insulin? She cannot tolerate it because 5 units cause her blood sugar to drop sharply, and the doctor still believes it is type 1?
Hi Sarah,
We shared your comment with Dr. Edelman, and this is his reply: "She needs a smart pediatric endocrinologist, and she needs to be tested for MODY."