DIY Biohacking: Do(n’t) Try This at Home
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- Опубліковано 16 чер 2024
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A mail-order CRISPR kit, manufactured by Dr. Josiah Zayner is turning the scientific and medical communities upside down.
Zayner, a biophysicist turned biohacker, believes we’re dragging our feet on realizing CRISPR’s potential. So his do-it-yourself CRISPR kit allows people to experiment with gene editing in the confines of their own homes.
Many critics argue that genetic engineering should be strictly left to the licensed and trained. However, Zayner thinks the possibly life-altering effects of CRISPR technology far outweigh any adverse concerns.
Zayner’s hope is to make CRISPR accessible to everyone, rather than limit its access to the rich and powerful.
Christopher Lewis Dawkins was mistakenly omitted from the video credits. Dawkins is the cinematographer for the story.
See the full article on biohacking and DIY gene editing here: www.freethink.com/shows/bioha...
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Should biohacking be enabled or restricted?
I think it should be regulated and licenced
Offcoarse right now it should be strictly restricted.
I believe you would never give a gun to a 8 year old. Would you..
arun yadav lucky his not an 8 year old right!
If you Google his info he is an accredited scientist. He seems pretty cool and apperantly knows what he is doing. I see no reason why he can't capitalize on his research.
We will see in a few years what promises or problems manifest.
@@MT-dh5mw yeah but what he is selling right now can be bought bought by anyone.
"You always imagine that doctors will be there for you, or scientists will be there for you, or somebody will be there for you. But, a lot of times it's just not the case"...... "Be your own hope"! Very well said!
Got tears in my eyes
He is entirely right, I'm currently forced to biohack my body with hormones because my countries medical system is gatekeeping me from getting them the official way
No one is coming, it’s up to us.
The big thing is...this tech WILL be used. We just need to make sure it's available to everyone not just elites and rich
The enlightened elites have probably have had access to this for decades.
That's the problem with every new tech pretty much. Access for poor people who may actually need it the most is often low.
finally I can use my money to get giga-chad genetics, and those poor people said you have to work for your body's physique, HAHA
Vaccines.
@@jesseyemichell7610 cool story bro
Dude's got a phd, worked for NASA. That's not ur regular DIYer. I feel like he may be qualified.
You don't need a PHD to use CRISPR
Yeah, now anyone can take a common germ or virus and turn in into a useful ultra-communicable, biological warfare agent. Good idea... real good idea.
CommonCentsRob
Same way free speech was dangerous and always controlled, the public is and can be stupid, and should be controlled just by the top?
It’s tough cuz I agree the masses are so insanely stupid. But at the same time I don’t think mass control is good, kills innovation.
@@carsonhunt4642 What are you going on about? Free speech is dangerous? Only to the simple minded who make it obvious they can't defend their views. You think tinkering with deadly viruses by the general public is 'innovation'? Wow. How is my statement wrong or false?
CommonCentsRob
The simple minded don’t have their own views. They’re just the sheep.
Cnn argues twitter should be banned because people can read “dangerous” things themselves on it, as opposed to just hearing what they’re supposed to hear.. Free speech was never allowed in past history because it “could” cause trouble.
My sarcasm about free speech is the same issue you have with crispr. Same argument applies to near any technology actually. Crispr is about the entirety of the human genome, not about viruses. The same way computers are about a million things. Could a bad egg make a bad virus on the computer with ill intent? Could someone use free speech to radicalize a small minority such as a cult? Despite the risks the benefits have always outweigh the cons.
You guys remember when this guy replaced his entire G.I. microbiome because it was failing him?? The man’s a legend and an inspiration. His philosophy on self-healing and his approach to science are absolutely nothing to be in up in arms about.
He is a wannabe punk hipster who clearly lacks fundamental knowledge of certain aspects of genetic engineering despite his phd.
Rick Mortar what fundamental knowledge of genetic engineering is he lacking?
@UCDFwNJrMGX0mQmsmZLwQFYQ He's already done similar stuff for NASA
@@rickmortar7886 Pretty sure he worked for NASA trying to modify Earth life so that is survives in a Simulacrum of Mars. They wouldn't keep him on for years if you were right.
@@rickmortar7886 I don't care if he was some shleb who didn't know anything. It's his body and his choice and risk to take.
That is dangerous but then that's how man learnt to light a fire....
Good point! A lot of progress has come with great risk - and you can get burned literally or figuratively.
Yes but once you know the potential of the Fire. You wouldn't light fire near gasoline.
@@R1L1. Fire and Biohacking are highly different but at the base level, humans took a risk and experimented with something may people warned them against. Sure, bad things happened. But we wouldn't be here without fire. And we are more advanced now so we can try to limit the ill effects.
Forks are dangerous if you jam them into your eyeballs, doesn't mean forks should be outlawed.
Also, we're all going to die anyway, so... simply living is the most dangerous thing you can do, because it has a 100% chance of resulting in death. Might as well try to accomplish something positive in the meantime.
I love how people are concerned about "bad stuff happening" when cigarettes and alcohol are legal 🫠. Makes sense.
Not to mention the long lasting effects of all these chemicals they scientists came up with that are pumped into the air and atmosphere on a daily basis. They find new chemicals and plastics in newly born babies everyday. Scientists love to pretend like they are so noble and "safe" yet scientists are responsible for some of the worst destruction this planet has ever seen. Some guy in a white lab coat had no problem creating Agent Orange for the government knowing full well what it would be used for.
I biohack every day via a dozen Krispy Kreme donuts.
A brute force biohack.
crispr kreme
@@icarokaue7334 it’s illegal that no one’s liking your comment
@@icarokaue7334 The fact that so few have seen this comment thread is proof that there is no justice in this world
DKM😂
Using DIY CRISPR to change one or a few specific genes in your DNA (to change a trait about you) is easy in theory, but incredibly difficult in practice. There's a reason why most single gene disorders don't have CRISPR-based treatments yet - it's not only difficult to DELIVER the CRISPR system reliably to your DNA to get a desired effect, but we also don't know about all the downstream and long term effects. Imo its quite important to know how complicated genetics is and those who don't understand this should stay away from DIY CRISPR. Open to discussion :)
I'm trying to follow up on his condition at the moment. But there's little to non information
if crispr can’t even cure a single gene disease then it means it deosn’t work
I got a DIY crispr kit and I was successfully able to engineer Lymphoma. 10/10, Do not recommend.
I think what that dope dude was saying and what Odin is doing is for a noble cause. Also I agree that having a select few that are rich and powerful, and in the most top of the top elites having the only access to something life saving is not a great thing.
Cool, thanks for commenting!
It's interesting to see the reaction in the comments vs our other videos. When we post videos about an innovative, lifesaving technology we often get comments like "but it'll only help the rich and powerful," or "it won't happen for too many years." This is the other end of the spectrum - enabling anyone to potentially get access to very advanced therapies for cheap - but we also see a lot of pushback, with people saying it's dangerous and should be illegal.
Perhaps the right answer is somewhere in the middle, as Zayner himself acknowledges, but he seems to see his role as pushing things back towards the cheap/accessible end of the spectrum.
Maybe we should let anyone who wants to, play with highly radioactive materials too! I'm sure someone will come up with something fascinating and useful!
Imagine someone trying to rob your house in the middle of the night, and you could just nuke them! That would be great.
This channel always put something interesting and totally different than normal thinking
This should be supported for small scale stuff like targeting enzymes. Thought Emporium on youtube already cured himself of severe lactose intolerance using this tech. Imagine for instance, editing genes so you can fully digest cellulose, making any leaf a calorie rich meal.
“Be your own hope”…. I agree with that statement 100%
I do really like this man. It seems he was trying to save many people's life. I hope he can keep doing what he want. Medical companies must hate him, the profits they want sounds really too much.
Probably too incompetent to actually hurt himself
I love this guy for no reason at all
This dude is the business! They should be pushing this tech, getting more people involved! Amazing stuff!
Remember kids, the government loves you very much, knows what's best for you and is using your money very efficiently.
F-35 program went efficiently.
@@XantheFIN Yup, Lockheed Martin is definitely government owned. And so is SpaceX.
@@mr.normalguy69 You know i referred to F35 program and not to company doing work.. Company was contracted do it. Not by themself. Company didn't or never does paying things for other one out of own pockets more than needed to get buyers. Welcome to industry world kiddo.
@@XantheFIN Government is the demand, F-35 program is the supply that won the competion for a 5th gen multirole stealth airctaft. There was a demand from a customer thus, it was responded with private solution. Welcome to economics.
@@mr.normalguy69 Nevermind lol.
This is very informative. Thank you freethink team for this. Love your stuff.♥
Agreed!
Appreciate it! Thanks for watching!
@@freethink could you please do a video on Thorium Nuclear Reactors and Small Modular Reactors (SMRs)
Thanks for the vid! So much to learn about biohacking…currently exploring nutrigenomics, DIY biology, and grinder.
Designer babies would be cool. Make them glow in the dark for the 1st few years of their life so you know where they are, you can save on night lights! Maybe make them bounce so they don't get hurt when they fall. You know the basic stuff!
uhhhh I mean I'm super supportive of genetic engineering but I think designer babies are a pretty unethical concept. IMO it should only be the choice of grown adults to genetically modify themselves.
Bouncy-ball babies
Give them 8 eyes so they can see all around them and make their fingers 3 times as long for optimal holding! You know the basic stuff!
Lol dude. You made my day.
Give them spider powers. The future web warriors.
I hope to get into this. This is next level self improvement.
i love you josiah bro!! i solute your thoughts!!
Imagine all of the underground biohacking thats happening as were watching this
Way more than you imagine. Thankfully, that process is going to no longer be an option in less than a year. Unless you know how to mix poison. Glad I did my bio hacks already for the most part.
Imagine how many involuntary bio hacking experiments are taking place
@@hiltonkuykendall9375 How do you get into biohacking? It seems like a really interesting emerging field in the future and I want to learn how to manipulate these tools.
@@icarus387 same
2021 world wide MRNA roll out ???
Interesting.. Knowledge is the key
New sub
Im 100% modifying myself into a super villain..
I totally agree with this guys message... but the mistakes made by the narrator in describing this technology (zero judgment or criticism from me you guys did a decent job compared to a lot of science journalism) do highlight the reason why science is elitist. It’s not that the information is necessarily locked away (it is...) but that it it sufficiently complicated that you can’t really understand it without training.
Also... He most likely did not transfer himself with the CRISPR construct he made... if I remember correctly he did not load it into a virus. So even if his chemical transfection method worked it probably had an undetectable change in the gene.
Thanks!
You're welcome, sorry we are just seeing this now! You can email me at toby@freethink.com and we'll send you a thank you gift!
I remember this guy from Unnatural Selection on Netflix.
Paul Pantea He reminds me of Rami Malek
Indeed!
Ooh wow
I think I will continue to watch it now.
I like this guy soo much, please let him know that 😂
Funny, because I can't stand him.
@@rickmortar7886 I feel that's what most people say about you...
@@somerandommen Imagine thinking I care what some random idiot on the internet thinks.
Me too.
@@rickmortar7886 addressing the random "idiot" as an idiot is proof that you do care what he thinks about you, because you were upset and called him an idiot. If you weren't outraged in the slightest bit you would not have expressed those emotions.
This is fascinating
Looking at this production quality, the view count always surprises me. Hopeful that the algorithm will smile upon the channel soon.
Please no...
When John Oliver says you're wrong, you're probably on the right track.
Too good man .
But ,there is problem gene editing is complex and could have undesired consequence .
So we should also have tools and mechanism to counter this .
If he wants to do it on himself, fair enough. I wouldn't buy a kit from him to do experiments on myself, I'd buy some weed from him though 😂
you just know he grows it or helps grow it
I'm gonna inject so much crispr that I become a super-villain
LOL
Not how it works
Finally something actually useful instead of just nfc chips that function the same taped on your hand as they do inside your hand
It went clear over my head, the point that is. Directly over my head.
this is what we have to do until "public" universities in the US are public again. Right now "science" is only accessable to those who can ace standardized tests and pony up $30k + a years tuition to look at ppt slides. There are a lot of innovative people out there that just want to do hands on science without the bureaucracy, elitism and high pricetag of a university.
seems like capitalism is the true villain
Good luck
I think he has some solid points. If we have a chance to prevent any disease or all of them so far we know. We should try that
Glad you liked it! Time will tell...
Its really hurt to see only 500k people subscriber for a quality channel which deserve 5m atleast.
People only care about what the media tells them to
I’m sorry, most people lol
Lol, anybody else notice one of the gals wearing a Jurassic park t-shirt?
We'd make a joke, but there are people using genetics to try and recreate dinosaurs: ua-cam.com/video/97raqm7sEDg/v-deo.html
Freethink “Your scientists were so preoccupied with whether or not they could...”
Freethink The endless struggle between Walt Disney’s views on technology and Mary Shelley’s.
We wouldn’t have cars if they were banned due to crashes
No cars would be a good thing. Hard to imagine since we've been brainwashed by the oil and auto industries.
I’m just saying. I’d be cool to have my tendons replaced with ostrich tendons. Who wouldn’t want to run over 40 mph?
thats what i was thinking too
You would also need the muscles and bones for that too, also you would need a larger heart and lungs to sustain long periods of running that fast.
@@Blablablablabla392 yeah that too
You wouldn’t be able to walk backwards then
one step closer to my army of wasp/spider/rats
It's not always 100% accurate in labs, that's why it's dangerous to even try it in garage
this guy is such a nerd, i love it
Dudes my hero.
I think he makes some valid arguments. I do think the risk is potentially high, but historically there have always been big risk takers that have made big breakthroughs. It's hard to say what's right here and i think that anyone who says it's easy to declare authoritatively one way or the other are selling something.
It’s not just self experimentation that I think Josiah is encouraging...it’s also “a valuable exercise in citizen science” ok they just said it
It's good that he's trying to spread it among everyone. It's just that we know so little about what DNA does that changing it can potentially mess you up. Hope people are aware when they buy from him
I'm so okay for Making science so much more available for independent passionate people. I find the current structure of science and control, holding back so much. Science should be happy because it's all just free research for them that "they don't have to be responsible for but can benefit from learning from the outcomes" so imagine human trials, where they don't have to be responsible and still gather insight from? They should love that. It's not going to stop big companies to continue to make Profits. They will always find ways, so idk why they have such a freak out reaction over anything that thinks outside the box...
SKEPTICAL PERSPECTIVE AHEAD: I understand (and personally agree with) the perspective that the FRUITS of this technology should be available to everyone regardless of race, gender identity, religion, sex, creed, social class, etc. That being said, I have a significant issue with the idea that the tools to edit the genome of an organism should be made available to anyone who wants it. CRISPR is in its infancy, it is already incredibly capable and nobody knows how much more capable and easy to use it will be in the future. It is currently within the realm of capability to genetically modify a deadly bacteria/virus and destroy humanity at a large scale. I don't think it's in our best interest to make such a powerful tool readily available. You're required to register your car, register firearms, register heavy machinery, boats, anything that can do damage. I believe every positive application of this technology should be equally available to anyone who needs/wants it, but open access is a recipe for disaster.
LMAO!!! Megan Hochstrasser's eye brow HAHAHHAHHH
he is an artist
this guy is Clovis Bray in the making !
I like this guy already...
So few views this video should have thousands of millions is an interesting information, i want to know more about this is just blow my mind. Yes it could be dangerous, this could cure a lot of disease but you never know to where this paths will lead you that is the risk.
i just added editing my own genome to my bucket list
It's not obvious which is the better choice, but my hunch is that it is GOOD that it is available to the public. The bureaucratic pipeline surrounding pharmaceuticals, therapeutics, and the FDA takes way too long, sometimes for good reason and sometimes for not so good reason. Regulations regarding participating in human trials VOLUNTARILY creates many scenarios where people dying of cancers, neurodegenerative diseases, various genetic disorders (like the neurodegenerative Huntington's disease) just have to sit and wait with crossed fingers for a new drug that shows promise to take 5 years to see if 100 people or whatever are positively influenced.
The people that will die from this will be few relative to the people constantly dying because of the bureaucracy of the 'official' pipeline. I'm not saying down with regulations, I'm just saying it should be the biggest priority in the world to reduce those regulations to the bare minimum possible to still allow for a high degree of safety.
not to mention it creates an opportunity for bioengineering garage startups, something not really possible back in the day; software was the only garage entrepreneurship for the most part that anyone could do. 3d printers made manufacturing and engineering startups possible. and this makes bioengineering startups with a very very very small budget possible.
I'm not saying bioengineers using diy crispr kits should be immediately injecting people, I'm saying it seems like a GREAT thing that they could do experiments on live cells and things like that in a petri dish.
Could you get rid of ADHD with Biohacking?
This is a dangerous premise.
It’s also very idiotic
I think that the scariest thing is that most people won’t have access to (or even care about) disposing their waste properly and there is no way of knowing what kind of effect that could have on the environment.
Not to mention intentionally malicious actors who would try and make something to actively harm other people.
It’s really scary to think about that. I work with Environmental Health and Safety for the research lab I’m at and some of the things the commonly used chemicals can do to the environment is crazy.
5:57 I think the Jurassic Park shirt is a little on the nose lol
UA-cam's algorithm slipped with this vid. This should've been in my recommended.
People doing to their bodies what they do their PCs. Yes. Certainly.
Science is for everyone. Do not continue to let others create our perception of reality.
You can bioengineer a short term solution to lactose intolerance. Someone on UA-cam did it with genetically modified yeast. Why isn’t this a big thing?
USA banned CRISPR embryo editing but GM food is legal.
There used to be diy crispr cas kit on amazon but not anymore.
My god, be careful people, for yourselves and the public.
Wasn't there a video game that had a similar premise? Oh yea Bioshock... cool to think about and explore in a video game but to do IRL I don't know
Well, not everyone. Most people can access it but it need to be control. Once you have the correct sequence for certain virus or bacteria, you can replicate it and then possibly spread either to an individual or a whole country.
he bout to be the first ripper doc
"Be your own hope"
I need to find this guy and get some modifications done.
He's now a 'woman' :(
I had no idea Ed Bassmaster has a PhD and worked at NASA.
Neat.
"would ya look at that? Just look at it!"
tech should be accessible to anyone
Cool!!!!!!!!!!
Feel like we are walking such a fine line next to a very very slippery slope
How should I start learning this skill? Where could I buy the tools?
I am just speaking off the top of my head here, but if someone will inject themselves with Black Tar Heroin and roll the dice to die then why not use your brain and body to educate yourself instead. At least this may give you a new love of science and an understanding of the human or the genome that could lead you to a new and productive use of the mind.
Not saying go out and try it but if you are about to throw your life away, then at least use it for good.
How long is the wait until the bio hack take effect? Are they talking to enhance brain function or cell growth, what about the elderly community? Would they be willing to try new medicine?
You don't control me. I'm installing a microchip in my brain right now just you wait.
Actually, it’s also illegal in China, that doctor He was sentenced to three years' imprisonment then.
This is the truth!
Hi where do you get these kits from ?
That's crazy 😲 , how long before it's a drug like thing???
I don’t care about the risks there might be. I would rather die instead of failing. I will go through anything to achieve my goal. There is no possibility of failure because I can’t fail. It’s not me just not wanting to fail, it’s me not being able to fail. Failure is not an option. I will do whatever it takes.
If there is bad grammar and bad punctuation deal with it if there is something you don’t understand ask
Real life Rick Sanchez
this guy does huge things yo
How do I get a kit and can I fix my PKD.
No one is coming to save us. There is no promised land, unsheathe the blade, and either die in glory, or trimputh forevermore
…okay but what did he actually do when he injected himself? What was he trying to do? I feel like that’s a super important part of the story here.
What's the worst that could happen?
haha, Dr. He was just out of the jail !!
Can't wait to make myself glow-in-the-dark
"We are doing everything for noble cause, our technology would save the world.
I tried to make a statement abot how rich get all the medicine and wanted to popularize it. For people's sake...
Did i say that we are gonna save the world?"
Describe tech, don't describe how important and influential it is.
Nukes are powerful too.
Doing this hurts the field itself by showing such recklessness
It reminds me of people int the first half of the 20th century who thought that radiation has some wonderous health benefits and started putting radioactive material into cosmetics and stuf...
Biohacking can be described as citizen or do-it-yourself biology. For many “biohackers,” this consists of making small, incremental diet or lifestyle changes to make small improvements in your health and well-being.
The early Cult Mechanicus
We use phones, cars and computers, now everyone tell me how it works :P