For all you can add a note, the Leptomeningeal Angioma in Sturge weber is usually ON SAME SIDE of the Port-wine stain. Thin of it: like if half of the face has port wine stain, this port wine stain will continue posteriorly to the same side ONTO the Leptomeninges Capillaries(inside the brain).
Just took my step 1 a week before this video was up. still happy this video exists. this topic is a pain, and now finally there's something that I can recommend for colleagues taking step 1.
Dirty you did it again. you shone a cool clear light on this eemingly confusing topic. Your caring heart comes through as we watch your teaching videos. Thank you so much for being there for us who are struggling to get through USMLE!
I am just learning for my German final medical exam and I am deeply impressed of your video! I really do thank you, I did not find any source which explains that quite difficult topic as understandable as you!
This is the best medical resource/content on youtube or any other platform so far. Thank you so much Dirty Medicine you have saved my ass from being toast in an exam countless times...I wish you well and hope you keep putting out such amazing content.🤘🏻✌🏻
I have this disorder NF1, I had tumours in my small intestine, I had the biggest tumour in 2018 in North America, i had 7 tumours, lost about 50% of my small intestine. Tumours in my eyes and the Octave Nerve, Ringing Ears.
For NF1, I just remember the phrase, "Bumpy brown kid." This describes the neurofibromas, the pigmentation of the skin and the eyes, and the fact that the onset is at childhood.
For VHL disease , you say the gene makes ubq 1a qhich shuts the complex that degrades proteins, then wouldn’t this gene cause less protein degradation?
The pathophysiology of SWS is wrongly said. Here the GNAQ gene mutation leads to activation of the gene and its function, as in normal embryo, GNAQ gets inactivated at 9 weeks of gestation, but remains active in mutated cells in SWS
Dirty please let me add sth for this great mnemonic … Tuberous Sclerosis … pronounce it: Tuberous Skinerosis.. for skin sx: Ash-leaf spots, shagreen, adenoma sebaceum, ungual fibroma on the skin of your finger. Taking my exam in few weeks, prayers 🙏🏼
Are the tram track calcifications in sturge weber due to leptomeningeal angiomas? If so are they on the same side or opposite side? First Aid says it's on the 'opposing gyri'
Great stuff as always! Big fan. I was wondering if it is important for the viewers to pay attention that in the HARP mnemonic it's hemangioblastoma and angioma- not vice versa (same shit for me but what if it is important) Thanks, Dirty, you are the best 👌
This is the highest quality content I've seen amongst all the resources, including the paid ones. Thank you!
Remember the TUBArosclerosis genes/chromosome with this numerical mneumonic:
TSC1: (8+1) = c9
TSC2: (8*2)= c16
Love you, man! Stay dirty.
For all you can add a note, the Leptomeningeal Angioma in Sturge weber is usually ON SAME SIDE of the Port-wine stain.
Thin of it: like if half of the face has port wine stain, this port wine stain will continue posteriorly to the same side ONTO the Leptomeninges Capillaries(inside the brain).
Neuro-Cutaneous
-->
Leptomeningeal Angioma (Neuro) + Port-Wine Stain (Cutaneous)
Just took my step 1 a week before this video was up. still happy this video exists. this topic is a pain, and now finally there's something that I can recommend for colleagues taking step 1.
did you have any questions on these on step 1?
Your channel is gold for USMLE. Thank you soo much for putting this up for free.
An add-on mnemonic for NF1: "I'll have a number 1, please. It's CUTE(-aneous neurofibroma) and de-LISCH-ous!"
Just wonderful addons bro😮❤
genius!!!!
CICLOPS
Cafe au lait spots
Intellectual disability
Cutaneous neurofibromas
Lisch modules
Optic gliomas
Pheochromocytomas
Seizures
Dirty you did it again. you shone a cool clear light on this eemingly confusing topic. Your caring heart comes through as we watch your teaching videos. Thank you so much for being there for us who are struggling to get through USMLE!
Your channel is the best for USMLE prep. Thankyou May God bless u always. Your mission to provide free education makes me teary eyes lots of prayers ❤
Thank you for keeping your resources free and helping to eliminate educational disparities, your channel is Amazing
I am just learning for my German final medical exam and I am deeply impressed of your video! I really do thank you, I did not find any source which explains that quite difficult topic as understandable as you!
Can’t thank this channel enough. Beyond grateful and obliged
Tuberous Sclerosis/TSC=> TS = tumor suppressor
In case for some reason knowing that it's a tumor suppressor in particular helps out.
This is the best medical resource/content on youtube or any other platform so far. Thank you so much Dirty Medicine you have saved my ass from being toast in an exam countless times...I wish you well and hope you keep putting out such amazing content.🤘🏻✌🏻
No other teacher/resource could ever match up to you 🙏🙌
Thanks!
best channel for mbbs students
One day all I want is to finally understand the difference between angiomas, hemangiomas, and hemangioblastomas...
For tuber sclerosis
Tubers are raised mass like potato
So potato in kidney, heart, nails, skin.
For Sturge-WEBer syndrome I think Whites of eyes Epidermis Brain thanks so much dirty you're the GOAT!
I have this disorder NF1, I had tumours in my small intestine, I had the biggest tumour in 2018 in North America, i had 7 tumours, lost about 50% of my small intestine. Tumours in my eyes and the Octave Nerve, Ringing Ears.
How are you doing now?
God help you get red if them😢
For NF1, I just remember the phrase, "Bumpy brown kid."
This describes the neurofibromas, the pigmentation of the skin and the eyes, and the fact that the onset is at childhood.
This is an outstanding presentation
By far the best video I seen describing these difficult concepts
Saw this bs on my step 2 prep drove me nuts but this video is great.
You're a blessing for med students 🤩🤩
This is an amazing vedio⚡️⚡️
Such a wonderful and useful video!
This content was amazing .... Dirty medicine never disappoints .... Amazing explanation
hahaha "That can quickliy spiral out of control if you dont know what you are doing" I LOVE IT... IDK why that made me laugh so hard! lol 😂
For VHL disease , you say the gene makes ubq 1a qhich shuts the complex that degrades proteins, then wouldn’t this gene cause less protein degradation?
Excellent summary multiple thanks
The pathophysiology of SWS is wrongly said. Here the GNAQ gene mutation leads to activation of the gene and its function, as in normal embryo, GNAQ gets inactivated at 9 weeks of gestation, but remains active in mutated cells in SWS
I was he'll afraid of this topic always but then you came in my life
Mnemonic for NF type I and Café-au-lait spots:
If you drink too much coffee (Café-au-lait spots), you are gonna go number one (a slang for pee).
I don't usually comment on videos but this is amazing!
Dirty please let me add sth for this great mnemonic …
Tuberous Sclerosis … pronounce it:
Tuberous Skinerosis.. for skin sx: Ash-leaf spots, shagreen, adenoma sebaceum, ungual fibroma on the skin of your finger.
Taking my exam in few weeks, prayers 🙏🏼
Bet vedio keep it up❤
Amazing..Thanks..Good Bless
best content ever! I cannot thank you enough!
good one.
for sturge-WEBer , you can put a cartoon photo for spider man (with his WEB mask covering his head , face , eyes 🕸🕷😉)
Maxim Al Ali can you add more of mnemonics in the comment pls.... this stg web thing is so much easy for me now after this video
Are the tram track calcifications in sturge weber due to leptomeningeal angiomas?
If so are they on the same side or opposite side?
First Aid says it's on the 'opposing gyri'
same side
Keep shining dear! You helped me a lot! Thank you so much
Your videos are amazing Sir. Just want to add a minor comment - TSC stands for Tuberous Sclerosis Complex I encountered at few places.
I'm so so so glad for this video!
Thank you for this amazing video!!!
Thank you so much for this video!!!
absolutely amazing.
Dirty your videos are the best. Thank u
Thanks, I will add: Sturge starts with letter S= Sporadic. 😁
Awesome video , thanks Dr 👍
Back here for STEP 2; thank you for helping me kill STEP 1 last year! You're a saint to us med students
THANKS A BUNCH 💟💫
Thank you man! This is gold!
Your videos are really valuable👍keep going.
Thank you.. I will study this
Thank you sooooooo much, you’re a gem 💎 !
Amazing lecture!! Thank you!
Thank you!!!💞💞💞
Thankyou so much ! I’m glad i found this👍🏻
Amazing explanation!
Thanks for your kind help😁
Perfect as usual
Great stuff as always! Big fan. I was wondering if it is important for the viewers to pay attention that in the HARP mnemonic it's hemangioblastoma and angioma- not vice versa (same shit for me but what if it is important) Thanks, Dirty, you are the best 👌
My comp is in a week brah! Thanks!
Best❤
ive also seen seizures in a kid with tuberous sclerosis as a big sign for it!
Is GNAQ mutation gain-of-function instead of knock-out/loss of function? It's activating mutation. Thank you
thank you!
This is helpful! Thank you
Hey!!!
Please make a video on dementia.. it’s getting very confusing
Incredible
Love you. Thank youuuuu
thank you
great.. thaaaanks
thank you!!!
Awesome
great stuff man
Legend 🎉
This is dirty indeed, but what a great job. Thank you.
Counting down 👀
Thanks a lot .This is like literally a life saver 😁❤️
I got picture of adenoma sebaceum on step 1 and asked for what other findings will be seen. I was like thank you dirty 🥺
👍👍
Thanks
Thank youuuuuu!
❤
🙏🏻🙏🏻🙏🏻
👏👏
I love you bro
2 ❤
dirtyusmle was a way better channel name, rolled of the tongue so well
I love u
I've forgotten to watch p*** after I found you.
Thanks!
❤