the only issue with Fin is that because it inhibits the production of DHT that means you generally have more free test in the body which can potentially higher your oestrogen levels also, and thats why some men can develop libido issues or physical problems like Gyno
Basically having low levels of testoerone or high levels of estrogen can mess with the eclectically activity in your heart. Before I started TRT when my test levels were like 250-320 at 34 years old I had palpitations all the time. Once I was on TRT for about 4 months and my test levels hover around 800 the palpitations are pretty much gone, so it was the low T that was causing it. If any anti androgen like RU58841 gets into your bloodstream somehow and messes with your hormones it will effect your heart negatively until it gets out of your system. Just make sure you have no open wounds on your head when you use these compounds and you’ll be fine.
@@jessie729 that subsides once your body regulates to the regimen. I had same thing, and it ended up going away. Your body can adapt to anything however you should always start at a low dosage then slowly increase to your desired dosage.
I wouldn't touch the stuff again. Not worth risking heart health for some hair. We don't know what it's potentially doing. Get a hair transplant and a derma roller and big 3 shampoo or get a hair system if your hair is beyond repair. I'm not gonna be a lab monkey 🐵
Hi Kevin, Your videos are really informational and I've recently bought some finasteride and I'm going to take them to the doctors with me to get his approval. What tests should I ask my doctor for to make sure I can minimise the chances of getting any sort of side effects. Like would tests showing my estrogen and testosterone levels help in making a decision as it could show I have low or high levels in either hormone?
Question; If you are non-responsder to FInasteride to the point that is makes your hair much much worse. And, assuming the poor results are NOT due to shedding would it be best to taper off Finasteride and start using RU? I mean if you are on Finasteride for say 2 years and your hair has gotten a lot worse since baseline then it means your DHT being blocked from Fin is actually working against your body chemistry?
If low testosterone causes heart problems, then wouldn't blocking androgen receptors have the same effect? RU58841 prevents testosterone from exerting its effect at the androgen receptor at the heart muscle like in the case when there is not enough testosterone in the bloodstream.
Hey Kevin! Great videos and thanks for everything your doing! Would really appreciate your thoughts on this. So I've been using RU 0.5ml on my research subject for a week now and they've noticed chest/heart pains which is new. It's not high blood pressure which I'm closely monitoring so wondering if they should just plow through it since it seems to be working, but I'm also terrified that I'm causing significant more harm than good. Also worth noting that they've been on fin for like 10 years (since 20 yrs old) and have never had any side effects that I know of. Should they maybe try CB? Thanks brother!
Hey mate, thanks for sharing your experience. How are you doing these days? Is your research subject still taking the drug? Any developments? Good or bad?
hi kevin im taking finasteride, minoxidil and nizoral to combat hairloss I am wondering what could I add to my regimen to combat it further? any response would be very helpful thank you
A few questions related to the video; 1) What's your view on Minoxidil side effects? I've noted that one potential effect listed online is also heart palpitations suggesting some detrimental effect on cardiovascular health. Also, many threads in hairloss forums about wrinkles and dark eye circles from Minoxidil. 2) How would you compare topical finasteride to RU58841 in terms of efficacy?
Sure. 1. Minoxidil is also an anti hypertensive drug so I could see this being an issue. It's rare but if you are experiencing chest pains on minoxidil I would definitely stop and speak to a doctor. 2. There is an in vivo study showing minoxidil is a collagen suppressor granted that is not strong evidence. I haven't experienced any sides but I use tretinoin which promotes collagen production on the skin so that might be what is helping. 3. RU is better imo since it suppresses both test and DHT unlike fin which just suppresses the latter.
Minoxodil really messed up my face. Like in a couple days had huge bags under my eyes. Luckily after I quit they went away though but the collagen effect for me atleast was definitely huge
Bad idea, you need at least a TRT base of testosterone to counter the suppression and all steroids are suppressive. Anavar is DHT based so it is not hair safe and furthermore it is VERY commonly faked as actual anavar is crazy expensive and it is often faked with dianabol which is very bad for the hair. As much as I wish otherwise, there is no hair safe steroid.
Is there any legitimate reason why the drug would have been abandoned if it has efficacy in treating androgenic alopecia? How can a person determine or make an educated guess as to why it was abandoned?
do you have video about what you think about Brezzula? heard their phase 2 with 7.5% concentration offers promising result , similar to finasteride but without the systemic side effects.
hi Kevin is your research subject still researching RU? Mine found it worked incredibly and hugely reduced shedding almost instantly but is experiencing chest pain and breathlessness after a week (15mg)
Haircafe good move. my research subject stopped it four days ago and is experiencing severe pain on the left side of the chest which continues to worsen following cessation but is hoping it’ll get better
@@haircafekevin Thanks dude, appreciate the response. What would you recommend for someone who’s beginning to thin and hair receded a bit? Early stages of mpb
Hey Kevin. I had some weird sexual side effects from Finasteride and im looking for something different. Would RU58841 cause the same thing? The website i get all the stuff that i trust has it but its in a powder form. Not exactly sure what type of liquid to add this too and how to measure how much to put on my head. Great video as always
Thanks for making this video Kevin, lots of great information. I was wondering what your opinion is on if RU and dutasteride would be overkill? I have responded mediocre to finasteride through 8 months. Thanks so much.
No problem and RU plus dutasteride is legit and probably the strongest stack you could use. You can nuke your DHT with Dut and take care of any remaining androgens on the scalp with RU. It is good for people when fin isn't strong enough.
Hey Kevin! Can you make a video about drugs that can cause hair loss (like beta blockers, methylphenidate, etc..) ? Thank you for your work by the way :)
What hairstyle do you ask/show your barber? I want something similar to yours but I’m not sure what I should tell my stylist. What cm do you get on the sides usually? Thanks!
Kevin Mann Cool, Thanks. Finasteride is working great for me by the way. Would you suggest Minox for diffuse thinning or should I stick with fin for hair loss and Toppik for cosmetic effect? Cheers Kevin
@@user-ql8oi9tv5x If Fin is working I don't think minoxidil will probably add much more density. If you don't mind using toppik I would just stick with that since I think its a Godsend for diffuse thinners.
Is there any work being done to make RU58841 available with prescription? It seems like an important long-term adjunct treatment for finasteride users.
Hey kevin great video! I was on oral finasteride for about 6 months, but the constant ball aches where getting to me. I want to start topical finasteride but i don't understand how this will work. Because it isn't a direct dht blocker it has to bind to 5 alpha reductase. Will it than bind to 5 alpha reductase in the scalp only? So it means that testosterone goes to your hairfolicels and then turns into dht? What about the dht being made in the prostate, doesn't that dht go to your hair anyway and start damaging your hair? Could you maybe do a video about this?
Thanks! There is actually a ton of alpha 5 activity on the scalp so yes topical finasteride will work by suppressing the DHT locally. It doesn't affect the prostate but that shouldn't be an issue unless you have BPH.
Hey Kevin, love your videos keep the content coming when you can. Ive got a question - do hair relaxers or hair straightening products cause damage to hair follicles? And if so, do you think its possible to chemically straighten hair without damaging them?
How do you feel about hair systems for guys who are like Norwood 7s? From what I seen they come a long way as far as looking realistic. If my hair ever gets to that point and we still don't have like hair cloning by then I feel like I'd have to get one
RU doesn't cause just low androgen levels, however. It doesn't effect serum androgens at all as you mention. But the concern is when it occupies the androgen receptor of a heart cell for instance, that receptor is 100% deprived of androgens. It's not just low androgens from the perspective of that receptor, it's literally 0 androgens. The question is if that is potentially damaging to cells or the heart. Not being a critic I just don't find this video convincing in terms of addressing heart related concerns regarding RU. If you have any insight into that, it would be nice.
From the research I’ve done, it seems possible however very unlikely that RU should reach heart cells. However, since the half life of RU is pretty short, if you experience such side effects you can discontinue the application without needing to worry too much
Yes, I do it because blocking dht alone isn't enough. If you started balding before 17 chances are your hair is also sensible to testosterone. Once you hit puberty, its fucked
@@emptysoul2757 every day. I use a shaving brush to apply it because my hair is kinda not Short and i found it to be the best way to uniformly and homogeneously apply it. Idk maybe 1 to 3ml of a 30mg/ml solution. I just pour some in the cap of the flask, dip the shaving brush in there.
Thanks for this vid. I've been thinking about starting RU. Is it necessary to take finasteride alongside, or is RU enough? I will also be on a test blast.
@@lynxpointlizard Thanks bud! And personally I prefer finasteride over RU because of its convenience. I can just take it like an aspirin and forget about it. I will use other compounds and at my most extreme I have used some really extreme stacks in attempts at regrowth but all in all I find I get all the results I want from just a basic finasteride/minoxidil stack.
Not enough evidence on that for me to be convinced. Mechanistic data is mostly useless other than just for establishing a hypothesis. Unless it can be demonstrated in clinical trials on actual human beings and not lab rats the I do not hold much faith in it.
Hey man. What do you think about prp injections? Are they even effective? They are actually cheap in my country, so i think to try them. I’m using finasteride already.
For the temples, if there is still some hair there then yes. For the hair on the side of your head, it won't matter. That's the Hippocratic wreath which is DHT resistant and hence used as a donor area for transplants.
@@haircafekevin The sides don't go completely but they do thin in balding men. So maybe they have a *minute* DHT sensitivity, just nowhere near as much as the top hair does? What do you think?
@@kingk892 tbh i haven't really noticed a difference.i recently stopped using ru but will continue useing fin min and a dermal roller. I havnt had any regrownth but i also havnt lost any grown the 4 years ive been on fin all the best Gl
I took it and within 4 days my chest gets super tight at night and hurts this is without me looking at any side effects I’m never ever using this stuff again
Hey!.. when I was 17 I started to notic some hair loss ...it's a Hereditary baldness like my whole family ... now i'm 18 and a month ago I started using both minoxidil and finasteride...but when I watched ur video talking about mistakes of hair loss I get scary a bit of the idea that i should stuck with it (minoxidil) for life.. should I stop minoxidil and stay on Propecia... need ur advice.
Stop propecia and keep minoxidil. Only start propecia when you're 21 just to be safe. At 18 your body most likely has not fully developed and needs DHT for proper development
@Douchebag Dan Thanks for the advice mate..seems that u are a doctor or so..any way. If u don't mind.. In your free time i'd love to send u a pic of my hair to see how it is for a 18yo boy.
20mg of it daily is enough to see results. Research has shown that 75-150mg of CB-03-01 daily can yield results, and this anti-androgen drug is 40 times LESS powerful than RU58851. With RU a much smaller dosage can be enough. At 5% strength you can use 0.5mL of the liquid to get 0.25mg of RU, you can divide that dosage into two separate ones to take twice a day, so applying 0.25mL of the liquid every 10 hours so. You don't have to make the solution yourself as you can get it pre-made, the KB solution is better according to anecdotals (although a few bucks more expensive). Where to buy it? I'm not saying the name of the website just so you don't think I'm advertising something, but vendors for this chemical are very few, only 2 or 3 websites sell it. Just google it. Take caution and do your research before you decide to take it.
Hey mate, thanks for sharing your experience. How are you doing these days? Is your research subject still taking the drug? Any developments? Good or bad?
What about cb-03-01? I suppose pretty much the same right? I have dupa alopecia and I read if I want to get a sustanon boldenone cycle I need to use ru or cb in order to don't lose more hair. I'm using finasteride and minoxidil.
Yeah, clascoterone is similar but it actually passed phase III clinical trials so it has a better safety profile, I'd trust that. If you're going to cycle you probably should add in a topical anti-androgen on top of the fin+minox stack.
If I use RU then get a transplant down the line I know that I’ll have to discontinue use for some time so I should expect all my hairs that have been preserved to fall? So would there be a point getting one
Do you know how long it takes for RU58841 to absorb before washing off? I know minoxidil solution takes up to 90 minutes to absorb before you can wash off and I’m going to mix it with the solution. Am I right to assume it’s dependant of the carrier hence RU would take 90 minutes if mixed with minoxidil solution?
Hey mate, thanks for sharing your experience. How are you doing these days? Is your research subject still taking the drug? Any developments? Good or bad?
Its undergoing phase II clinical trials still as far as I understand. It looks promising but we'll have to wait and see what comes of it. It wouldn't be the first time an apparent cure has been discovered only to become a fart in the wind so even though I'm optimistic I'm not going to draw any conclusions yet.
Came here cause 5% minox was giving me heart palpitations :(. Would you recommend 2% minox if I don't get heart palpitations? I'm worried that even if I don't feel it it could still effect my heart.
@@dilrajkhangura3859 tbh i dropped ru i was on it for 8 months and no growth nothing even when i discontinued it there was no shedding nothing basically snake oil for me that is
I think I gave myself a nocebo effect because of the formums stating that heart problems could happen when it's not true and "instantly" got chest pains, used it for 2 weeks and noticed less shedding in the first 2 days and started notice it working.
Hello Kevin, have you heard about the forum gossip of the 23 year old who supposedly took 3 doses of RU and developed heart failure? Can you explain how or why this could have happened or maybe address it in a future video?
Kevin, for mild Alopecia areata, will fin and min work? Is there an ideal topical for alopecia areata? Also, if I get a transplant for the affected area, what's the risk of another AA attack?
Finasteride won't since that specifically treats androgenic alopecia. Minoxidil might though since it is a non specific hair growth agonist. Alopecia areata is pretty rare though. I've seen people who think they have it when it is really just androgenic alopecia so make sure a dermatologist confirms the diagnosis.
@@haircafekevin Got it. Many thanks. I had a transplant surgeon actually do a free consultation and he said the same thing. He said areata is rare and androgenic alopecia is often mistaken as other issues. I told him a fungal infection/seborrheic dermatitis caused my hair loss. He said that doesn't happen. It's androgens... There just may have been a simultaneous fungal infection present.
About 3 weeks into using RU 58841 for the research subject, I love it & no sides reported on 10mg 4x/ week, is this generally enough to get hair regrowth/ recovery for diffuse thining of research subject? Or are increases in frequency, dose needed to achieve any regrowth? (Slight dizzy on 20mg once)
10 to 20 mg are the best tolerated doses based on anecdotal reports. Sadly we have no clinical data on RU since it was abandoned during clinical trials so there is no standardized dosing.
For a person on deca and test, they can not use finasteride or itll make androgenic alopecia worst. Do you know if dosing RU once a day would be enough ? do you know ru's half life and how long it would protect from dht and test in the scalp? do you know since nandrolone (deca) and a 5-ar inhibitor makes hair worse, so far ru and nandrolone(deca) looks like it doesn't make hair loss worst?
It's hard to say, depends on the individual but using RU would certainly be better than doing nothing. Deca without fin is pretty harmless on the scalp so it would depend on how much test you are using. RU has a short half life, just a few hours I believe but it outright kills androgens on the scalp so it can be used just once daily or even every other day. Stacking test with deca is a must so RU is a good alternative to finasteride in this case.
@@haircafekevin Thanks for your help, I appreciate you and these videos You're a extremely intelligent guy in regards to androgenic alopecia and so thankful for you
Assuming most people wait until some of these new drugs are FDA approved, are any of the other topicals like (Redensyl,Procapil, Capixyl) worth using in the mean time as an adjunct to topical minoxidil and topical/oral finasteride? There is some initial evidence of effectiveness for a combination of those 3 compared to topical Minoxidil results but I haven’t seen a study reproduce the results.
It couldn't hurt, I find stemoxydine works well as an adjunct growth stimulant to minoxidil since it works differently but there is definitely no growth stimulant I would replace with minox.
I’ve never seen any good review for Redensyl growing hair and believe me I’ve looked, not counting the reviews of companies selling the product because those are always fake
Hi Kevin, Im 22 yrs old and a 3 vertex. I've been using fin since march 12th and have been shedding even more which I've read also can be normal. I understand that fin doesn't takeaway all dht on the scalp and testosterone on the scalp also causes hair loss. I haven't had any side effects thankfully. Whats your take on taking fin and RU58841 at the same time? Thanks Kevin
I think that you should hold off and be very patient. Let the finasteride do its job, then asses your hair at the year mark and even the two year mark. It took a good two years before I truly saw the progress from finasteride. That's the not case for everyone. The goal to keep in mind is minimal effect dose. Add things on one at a time so that you're getting the results you're looking for using the least amount of drugs possible. At the two year mark I added minoxidil to my hairline and at the 6 month mark in already making more progress. If it ever stops working then I'll asses and an anti androgen like topical finasteride or maybe something herbal that has shown to help. I.e. saw palmetto. I wouldn't use ru until a last ditch effort.
@@johncole4882 yeah, I think its a little understated how long it actually takes for finasteride to work, I didnt start noticing real results until about a year into it. People talk about like 3-6 months in you should see results, I guess everyone is different.
There is no data sadly. Clinical trials on RU were abandoned so most of the data we have to go on is anecdotal. On the bright side there aren't many people who complain of side effects and the ones who have were people using ridiculously large doses, like 100-150 MG per day. Even just 20 MG per day on your research specimen is sufficient.
My research subject Took ru today for the first time, some heart palp, erection is gone. So ru is not a option. I try cb now on my Research subject. Do you know when the ru is out of the system and how I can recover from the sides?
@@thecanadakid7622 used 1ml and even lowered it to 1/2 a ml when i got sides. chest issues stopped right after i discontinued use and i used for around 5 months.
@@mathieu4069 I got sides from minoxidil and ru and even scalp zits from nizoral so I don’t want to take chances with cb or fin I’m probably predisposed to get sides because my genetics
Hey Kevin, I’m starting on my journey of attempting RU , part of me feels frightened, am I worrying unnecessarily, how have you found it? I’m starting quite low 25mg daily
st helens villain, Hi I got my RU58841, but was thinking not to use it bcoz I got scared if I get sides, but if I use a small amount like you twice or once a week, would that b ok?
Hey Kevin, thanks for your great content chief! I’m currently 19 years old. And was diagnosed with Male pattern Baldness (blood test was ok) honestly fin and minox and ru are no solution for me. I think the only way I can get mz hair a hair back is a stem cell therapy in combination with a prp. Would you reccomend it? Is there a way I can contact you private? Honestly I’m so desperated and depressed because of my hairloss, it affects me in a very negative way...
If you're truly that desperate, why are you neglecting the only methods that works for hair loss instead of trying them for yourself and seeing whether they work or they don't? Lol.
@@Reloaded9923 fin- side effects, minox- side effects and twice per day for your lifetime is very heavy and it could make your existing hair dependent on that medication
Its RX only in the USA. You can get it on the grey market but it would be illegal for me to give a source. Loniten is common on online pharmacies though.
Minox is not worth it in my opinion. Yes it makes your hair grow faster but id pick fin + ru over anything else. I take 1mg fin in the morning and at night with biotin(2mg a day). March will be 1 year on fin and it’s definitely saved my ass but I’m greedy and might switch to dutasteride for some time and see what happens. RU nightly for about 5-6 months and I derma roll once a week and skip topicals that day and sometimes the day after. Ketoconozole 2% shampoo every 3 days or so. Also worth mentioning I quit minox cold turkey about 8 months in and didn’t shed that bad.
I buy premixed from anagenic. Really want to start mixing my own soon but haven’t pulled the plug on it yet. Nice that you switched to dut after a year, really considering making the switch. Got a bunch of it sitting in my bathroom that I’m too scared to take aha. Any sides? I never have any from fin 2mg a day so I’d expect not to get any but I know it’s much stronger.
Hard to say how helpful it has been because of other factors. I think the combination of fin + ru works better than either by themselves. My hairline is not amazing but compared to pictures I took a year ago it’s 10x better. Still receded but much thicker than it was headed. Will probably switch to dut after a year and give it a try for at least 6 months or so.
Hi Kevin. Due to side effects of 10,5 months use of Finasteride (Gyno), I decided to transfer to RU 58841. I ordered 2 bottles of 5% solution and plan to start this week. 1. Is there anything in particular that I should be aware of while using RU, and are there any precautions or protection against development of androgen deficiency side effects or cardiovascular issues ? 2. I have diffuse thinning, so I wonder If you can share your experience about the proper dosage of RU per day? Would 1 ml per day be sufficient against AA? Thank you for the reply and keep up the good work. Andrej
@@michaels999 Hello. I have been using RU 58841 on my research subject for almost three and a half months. Two weeks after the introduction of the treatment, I noticed an increased shedding, which lasted for almost 2 months with great intensity. I am now in a state of plateau (without significant loss), and the condition is slowly normalizing. Without visible hair thickening effects so far (Prior to the end of the first six months it would be too early to give an assessment).The strength I use on my research subject varies from 5% solution to 8% solution (the raw powder is mixed with ethanol-PG). No side effects so far. I hope that this info will be helpful.
@OMENITOLDYOU Hello, and thanks for sharing. Any assessment of the efficacy of MPB prevention medication before the expiration of the first 6 months of introduction of the treatment would be premature. From my previous experience in the last 19 years using a variety of medications for prevention of MPB, I can confirm that the use of each drug (minoxidil, finasteride, ketoconazole, saw palmetto etc.) has a different effect on each individual. Since I'm not a doctor, I wouldn't allow myself the luxury of making an unsubstantiated claim as to why RU in your case caused side effects in such a short period of time. Taking into account the experience of many users, though it is an experimental substance, in small doses RU has a pretty solid efficiency/side effect free ratio. Relating to your question, the shedding after introducing RU amounted to 30-40 hairs per day over a period of nearly 2 months.
Hey Kevin, i know you’re not a doctor. My wife got pregnant while I am on finasteride. I only take finasteride twice weekly, but I believe I took one the day she got conceived, what’s your opinion on this? Should I ask the doctor?
About 33 percent of people get some regrowth from finasteride but I wouldn't expect any miracles like regaining a norwood. I got some regrowth but it was in the areas where I still had hair and the hairline is the area of the scalp which for most people is most sensitive to androgens hence why it goes away first usually. I would get on finasteride to stop any further loss and then save up for an FUE. An FUE is easily the best decision I have made in my hair loss journey. I went from a Norwood 4 to maybe a Norwood 2 at the very worst.
Am on finas + minox , and thinking going your path of having an fue to restore the hairline but at the same time afraid of the shock loss situation of my existing hair i don’t want them to thin
Mix some jojoba oil with the ketoconazole shampoo or use it afterwards as a conditioner, it helps counter the dryness. I'll use a generic variation of head and shoulders typically as my regular shampoo or a coal-tar shampoo every now and then.
Thanks for the videos dude. Can I ask what your current regime is and did you stop taking dutasteride? I've been on finasteride for 3 months, no sides effects but not much change either. Looking to test out dutasteride. Thanks
No problem, thanks for watching. Right now I am just taking finasteride and minoxidil while occasionally using alfatradiol. I have stemoxydine I might cycle in early next year as well to see if I can get any additional regrowth. I don't take dutasteride although I felt it worked well enough albeit not noticeably any better than finasteride in my case, I just didn't like that is a softgel because I'm vegan.
@@haircafekevin Thanks for the reply! I'm going to go pharmacy today and pick up some dutasteride and give it a try. Did you cycle it with finasteride or just take it individually? One last thing did you notice any additional shedding switching both to and back. Thanks
@@themetamind9305 No problem. I used it individually and took it with finasteride daily for several months. I didn't get any shedding but that's likely because the mechanism of action of the two drugs is similar enough.
Great info as always - very reassuring to know the best facts available, plus informed opinion to put them into perspective.
Great content, still waiting for you patreon ;).
All this time i save... watching you sift trough all this valuable info.
the only issue with Fin is that because it inhibits the production of DHT that means you generally have more free test in the body which can potentially higher your oestrogen levels also, and thats why some men can develop libido issues or physical problems like Gyno
Thanks for the great video Kevin!!
Of course, thanks for watching.
kevin is my hero on the topic of hair loss!!
Basically having low levels of testoerone or high levels of estrogen can mess with the eclectically activity in your heart. Before I started TRT when my test levels were like 250-320 at 34 years old I had palpitations all the time. Once I was on TRT for about 4 months and my test levels hover around 800 the palpitations are pretty much gone, so it was the low T that was causing it. If any anti androgen like RU58841 gets into your bloodstream somehow and messes with your hormones it will effect your heart negatively until it gets out of your system. Just make sure you have no open wounds on your head when you use these compounds and you’ll be fine.
@@jessie729 that subsides once your body regulates to the regimen. I had same thing, and it ended up going away. Your body can adapt to anything however you should always start at a low dosage then slowly increase to your desired dosage.
@@cinzley244 how long til RU stop giving you heart palpitations
I wouldn't touch the stuff again. Not worth risking heart health for some hair. We don't know what it's potentially doing. Get a hair transplant and a derma roller and big 3 shampoo or get a hair system if your hair is beyond repair. I'm not gonna be a lab monkey 🐵
Hi Kevin,
Your videos are really informational and I've recently bought some finasteride and I'm going to take them to the doctors with me to get his approval. What tests should I ask my doctor for to make sure I can minimise the chances of getting any sort of side effects. Like would tests showing my estrogen and testosterone levels help in making a decision as it could show I have low or high levels in either hormone?
Question; If you are non-responsder to FInasteride to the point that is makes your hair much much worse. And, assuming the poor results are NOT due to shedding would it be best to taper off Finasteride and start using RU? I mean if you are on Finasteride for say 2 years and your hair has gotten a lot worse since baseline then it means your DHT being blocked from Fin is actually working against your body chemistry?
You should post more dude!! love your content as I am a 23 year old experiencing hair loss :/
Thanks man, I enjoy creating videos so I plan on it.
Yup he's a good man and provides the important information based on experience and facts.
@Mauri Mela ?
Mauri Mela can you expand on this bro? Bone broth? I’ll add this to my own natural regimen
@Mauri Mela Get real, please.
I like how you said for legal purposes, "my research subjects" and not "myself"
Is it actually a crime to use ru58841 on oneself?
If low testosterone causes heart problems, then wouldn't blocking androgen receptors have the same effect? RU58841 prevents testosterone from exerting its effect at the androgen receptor at the heart muscle like in the case when there is not enough testosterone in the bloodstream.
Mate I dunno but it's as if this guy takes a fat line of coke before every video the guy is lit! He's going 90 mph lol
Uhh.... i think he has normal speed. Almost slow. Your must speak really slow I guess
he talks almost as fast as ben shapiro
It's very easy to speak this quickly if you research a topic well.
He's just really well versed on the topics he discusses.
Finasteride it s more powerfull than cocaine ...he has too much production of free testosterone in the body...that s the reason hihhi
thank you for being the only reasonable guy to recommend 10-20 mg not 50-100 mg RU…
Hair is looking ver ygood man congratz on ur long term succes.
Thanks!
@@haircafekevin And thank u for inspiring me to fight my hair loss and all the great information.
Hey Kevin! Great videos and thanks for everything your doing! Would really appreciate your thoughts on this. So I've been using RU 0.5ml on my research subject for a week now and they've noticed chest/heart pains which is new. It's not high blood pressure which I'm closely monitoring so wondering if they should just plow through it since it seems to be working, but I'm also terrified that I'm causing significant more harm than good. Also worth noting that they've been on fin for like 10 years (since 20 yrs old) and have never had any side effects that I know of. Should they maybe try CB? Thanks brother!
get off it right now. This is a research chemical, how are you doing now?
Hey mate, thanks for sharing your experience.
How are you doing these days? Is your research subject still taking the drug?
Any developments? Good or bad?
Hey man! Any updates on this?
i using ru since 2020 and never had any hart problems. Maybe ru its not for everybody.
Oh shit he died
Kev, thank you again for a very informative information. I have been stacking minoxidil and propecia. What's your take on micro needling?
hi kevin im taking finasteride, minoxidil and nizoral to combat hairloss I am wondering what could I add to my regimen to combat it further? any response would be very helpful thank you
RU5
What is your current hair stack? Does your research specimen still use RU?
Thanks for the great content Kevin.. This may be a dumb question, but what do you mean by "research subjects" in regards to using ru58841 ?
It’s to protect himself from a legal point. It supposed to be used only for research purpose
Research subject actually means himself. He just didn't want to get into trouble with the law.
No he has an stuffed dinosaur who used the RU
@@Rebel.Extravaganza😂
A few questions related to the video; 1) What's your view on Minoxidil side effects? I've noted that one potential effect listed online is also heart palpitations suggesting some detrimental effect on cardiovascular health. Also, many threads in hairloss forums about wrinkles and dark eye circles from Minoxidil. 2) How would you compare topical finasteride to RU58841 in terms of efficacy?
Sure.
1. Minoxidil is also an anti hypertensive drug so I could see this being an issue. It's rare but if you are experiencing chest pains on minoxidil I would definitely stop and speak to a doctor.
2. There is an in vivo study showing minoxidil is a collagen suppressor granted that is not strong evidence. I haven't experienced any sides but I use tretinoin which promotes collagen production on the skin so that might be what is helping.
3. RU is better imo since it suppresses both test and DHT unlike fin which just suppresses the latter.
Minoxodil really messed up my face. Like in a couple days had huge bags under my eyes. Luckily after I quit they went away though but the collagen effect for me atleast was definitely huge
Hey Kevin what do you think about Anavar only cycle and Mpb suffers? I've heard a lot of people can get along with that
Bad idea, you need at least a TRT base of testosterone to counter the suppression and all steroids are suppressive.
Anavar is DHT based so it is not hair safe and furthermore it is VERY commonly faked as actual anavar is crazy expensive and it is often faked with dianabol which is very bad for the hair.
As much as I wish otherwise, there is no hair safe steroid.
Is there any legitimate reason why the drug would have been abandoned if it has efficacy in treating androgenic alopecia? How can a person determine or make an educated guess as to why it was abandoned?
do you have video about what you think about Brezzula? heard their phase 2 with 7.5% concentration offers promising result , similar to finasteride but without the systemic side effects.
This guy would be great in sales
think he actually works as a sales rep, but yeah you're right!
@haircafe where do you get you’re ru58841? Also you should do a video on how you apply your topicals
I got it from kane shop. I just took a 10 MG scoop and would mix 20 MG into 3-6 ML of stemoxydine before applying it to my research subject.
hi Kevin is your research subject still researching RU? Mine found it worked incredibly and hugely reduced shedding almost instantly but is experiencing chest pain and breathlessness after a week (15mg)
Nah, he dropped it. Too uncertain due to the lack of clinical trials.
Haircafe good move. my research subject stopped it four days ago and is experiencing severe pain on the left side of the chest which continues to worsen following cessation but is hoping it’ll get better
@@haircafekevin What topical and regimen are you using?
@@Wsox1994 At the moment just finasteride 1.25 MG daily and topical minoxidil once daily.
@@haircafekevin Thanks dude, appreciate the response. What would you recommend for someone who’s beginning to thin and hair receded a bit? Early stages of mpb
Hey Kevin. I had some weird sexual side effects from Finasteride and im looking for something different. Would RU58841 cause the same thing? The website i get all the stuff that i trust has it but its in a powder form. Not exactly sure what type of liquid to add this too and how to measure how much to put on my head. Great video as always
Anageninc or chemyo.Get your premixed RU from there.
Do you think the standard dose (50mg) on a research subject is too high?
Thanks for making this video Kevin, lots of great information. I was wondering what your opinion is on if RU and dutasteride would be overkill? I have responded mediocre to finasteride through 8 months. Thanks so much.
No problem and RU plus dutasteride is legit and probably the strongest stack you could use.
You can nuke your DHT with Dut and take care of any remaining androgens on the scalp with RU. It is good for people when fin isn't strong enough.
Kevin Mann You on insta?
@@Zach_Rowen No, not yet, planning on it soon.
Hey Kevin! Can you make a video about drugs that can cause hair loss (like beta blockers, methylphenidate, etc..) ?
Thank you for your work by the way :)
Thank you, and that is a good idea. I'll do some research.
Hey where is a source you can trust to purchase this stuff? For research, of course.
anagenic is the gold standard when it comes to this stuff.
Does ru have depending mechanizem?
Like minox?
Or the gains from ru could keep on fin alone?
It is an anti androgen so you could switch to fin and vice versa without losing anything.
What hairstyle do you ask/show your barber? I want something similar to yours but I’m not sure what I should tell my stylist. What cm do you get on the sides usually? Thanks!
Just 3 CM fade on the side and then tell them to take a little off on the top.
Kevin Mann Cool, Thanks. Finasteride is working great for me by the way. Would you suggest Minox for diffuse thinning or should I stick with fin for hair loss and Toppik for cosmetic effect? Cheers Kevin
@@user-ql8oi9tv5x If Fin is working I don't think minoxidil will probably add much more density. If you don't mind using toppik I would just stick with that since I think its a Godsend for diffuse thinners.
Is there any work being done to make RU58841 available with prescription? It seems like an important long-term adjunct treatment for finasteride users.
Nope
Hey kevin great video!
I was on oral finasteride for about 6 months, but the constant ball aches where getting to me. I want to start topical finasteride but i don't understand how this will work. Because it isn't a direct dht blocker it has to bind to 5 alpha reductase. Will it than bind to 5 alpha reductase in the scalp only? So it means that testosterone goes to your hairfolicels and then turns into dht? What about the dht being made in the prostate, doesn't that dht go to your hair anyway and start damaging your hair? Could you maybe do a video about this?
Thanks! There is actually a ton of alpha 5 activity on the scalp so yes topical finasteride will work by suppressing the DHT locally.
It doesn't affect the prostate but that shouldn't be an issue unless you have BPH.
Hey Kevin, love your videos keep the content coming when you can. Ive got a question - do hair relaxers or hair straightening products cause damage to hair follicles? And if so, do you think its possible to chemically straighten hair without damaging them?
Does your test subject have ru put in minoxidil or used seperately Kevin ?
What do you do? I do both but I don’t know any better. It does work for me tho
How do you feel about hair systems for guys who are like Norwood 7s? From what I seen they come a long way as far as looking realistic. If my hair ever gets to that point and we still don't have like hair cloning by then I feel like I'd have to get one
I think they look really good, definitely way better than they did 20-30 years ago.
RU doesn't cause just low androgen levels, however. It doesn't effect serum androgens at all as you mention. But the concern is when it occupies the androgen receptor of a heart cell for instance, that receptor is 100% deprived of androgens. It's not just low androgens from the perspective of that receptor, it's literally 0 androgens. The question is if that is potentially damaging to cells or the heart. Not being a critic I just don't find this video convincing in terms of addressing heart related concerns regarding RU. If you have any insight into that, it would be nice.
www.ebay.com/itm/124379788643
Why would it occupy 100%? It doesnt occupy nearly as much on the application site, so why would it do that on the heart?
Is there actual evidence that Ru cause hearth problems and what do you think about it ?
From the research I’ve done, it seems possible however very unlikely that RU should reach heart cells. However, since the half life of RU is pretty short, if you experience such side effects you can discontinue the application without needing to worry too much
What about castratos who have practically zero androgens their entire lives? They put live everyone
Hey Kevin is it safe to use oral dutasteride and RU at the same time?
Yes, I do it because blocking dht alone isn't enough.
If you started balding before 17 chances are your hair is also sensible to testosterone.
Once you hit puberty, its fucked
@@nostro1940 how often do you apply RU? And how much?
@@emptysoul2757 every day. I use a shaving brush to apply it because my hair is kinda not Short and i found it to be the best way to uniformly and homogeneously apply it.
Idk maybe 1 to 3ml of a 30mg/ml solution. I just pour some in the cap of the flask, dip the shaving brush in there.
Thanks for this vid. I've been thinking about starting RU. Is it necessary to take finasteride alongside, or is RU enough? I will also be on a test blast.
RU in my research subject is sufficient as a stand alone anti-androgen in my opinion and can be used as a replacement for finasteride.
@@haircafekevin Thank you Kevin, for all of the videos and info you upload. You look great!
@@haircafekevin Actually I have another question, which would you take, RU or fin?
@@lynxpointlizard Thanks bud! And personally I prefer finasteride over RU because of its convenience. I can just take it like an aspirin and forget about it.
I will use other compounds and at my most extreme I have used some really extreme stacks in attempts at regrowth but all in all I find I get all the results I want from just a basic finasteride/minoxidil stack.
Is 1.5 gr per month a good amount?
What could I use to thicken hair besides fin and minoxidil? I've been using both for over a year, but need something additional
Serioxyl stemoxydine or alfatradiol. Also you could upgrade to dutasteride.
Dermaroller
Can someone tell me where they buy RU thats a legitimate source?
There is also links of RU58841 to blood cancer, what are your thoughts on that?
Not enough evidence on that for me to be convinced. Mechanistic data is mostly useless other than just for establishing a hypothesis. Unless it can be demonstrated in clinical trials on actual human beings and not lab rats the I do not hold much faith in it.
Hello, what t shirt is that? It looks beautiful.
Hey man. What do you think about prp injections? Are they even effective? They are actually cheap in my country, so i think to try them. I’m using finasteride already.
They're a little too new and experimental for me to be convinced, maybe they work but I wouldn't expect miracles.
Too little evidence for now.
I wear a hair system but I want to rub RU on my temple points and sides to prevent further recession and thinning. Would this work?
For the temples, if there is still some hair there then yes.
For the hair on the side of your head, it won't matter. That's the Hippocratic wreath which is DHT resistant and hence used as a donor area for transplants.
@@haircafekevin The sides don't go completely but they do thin in balding men. So maybe they have a *minute* DHT sensitivity, just nowhere near as much as the top hair does? What do you think?
Good info Kevin. Keep it up
Thanks!
How do you explain Brian fog associate with finasteride?! It seems as if DHT has a bigger role than you stated.
MIRIN GAINES wait a minute.. I didn’t sign up to finasteride for some random Brian to come round
It isn't because of the DHT, it's because of neuro steroids which finasteride can indirectly suppress which causes some people to get brain fog.
Will RU inhibit future beard gains made with minoxidil? Is RU that strong it will inhibit androgens on the face?
No, it only works locally.
Finally someone who talks about it
Do you have a gaming channel watching you play games would be awsome
Hey kevin i watch youre videos all the time quick question Would it be safe to dermal roll and use ru?
Thanks and yeah, just make sure you don't bleed from it.
I was planning on derma rolling and using ru, considering it’s been 9 months I’m assuming you’ve tried doing it so I want to ask how’d it go?
@@kingk892 tbh i haven't really noticed a difference.i recently stopped using ru but will continue useing fin min and a dermal roller. I havnt had any regrownth but i also havnt lost any grown the 4 years ive been on fin all the best Gl
I took it and within 4 days my chest gets super tight at night and hurts this is without me looking at any side effects I’m never ever using this stuff again
Hey Kevin, where do you purchase your RU58841?
kane boss
Hey!.. when I was 17 I started to notic some hair loss ...it's a Hereditary baldness like my whole family ... now i'm 18 and a month ago I started using both minoxidil and finasteride...but when I watched ur video talking about mistakes of hair loss I get scary a bit of the idea that i should stuck with it (minoxidil) for life.. should I stop minoxidil and stay on Propecia... need ur advice.
Stop propecia and keep minoxidil. Only start propecia when you're 21 just to be safe. At 18 your body most likely has not fully developed and needs DHT for proper development
@Douchebag Dan
I'll do...thanks mate i appreciate it
@@saturn724
Ok..I'll stop fin...thanks mate i really appreciate it
@Douchebag Dan Thanks for the advice mate..seems that u are a doctor or so..any way. If u don't mind.. In your free time i'd love to send u a pic of my hair to see how it is for a 18yo boy.
How much ml and at what concentration did you use RU on your research subject?
6 MLS for full scale coverage with 20 mg of ru mixed in
Three Questions:
1. How much should I use a day? (times per day, percent)
2. How do I make the solution?
3. Where do I buy it?
20mg of it daily is enough to see results. Research has shown that 75-150mg of CB-03-01 daily can yield results, and this anti-androgen drug is 40 times LESS powerful than RU58851. With RU a much smaller dosage can be enough. At 5% strength you can use 0.5mL of the liquid to get 0.25mg of RU, you can divide that dosage into two separate ones to take twice a day, so applying 0.25mL of the liquid every 10 hours so. You don't have to make the solution yourself as you can get it pre-made, the KB solution is better according to anecdotals (although a few bucks more expensive). Where to buy it? I'm not saying the name of the website just so you don't think I'm advertising something, but vendors for this chemical are very few, only 2 or 3 websites sell it. Just google it.
Take caution and do your research before you decide to take it.
@@saturn724 why twice a day?
Kevin, how many days does RU can last if I mix it with minoxidil then put it on fridge?
Hey mate, thanks for sharing your experience.
How are you doing these days? Is your research subject still taking the drug?
Any developments? Good or bad?
Will this be needing a redoing or we still good?
What about cb-03-01? I suppose pretty much the same right? I have dupa alopecia and I read if I want to get a sustanon boldenone cycle I need to use ru or cb in order to don't lose more hair. I'm using finasteride and minoxidil.
Yeah, clascoterone is similar but it actually passed phase III clinical trials so it has a better safety profile, I'd trust that. If you're going to cycle you probably should add in a topical anti-androgen on top of the fin+minox stack.
@@haircafekevin thanks for your reply.
Hello Kevin, do you know of a trusted supplier i can buy RU58841 from in Europe? cheers
quase3 thekaneshop
I've noticed an improvement with my acne while being on finasteride. Is this normal?
Yes. Finasteride blocks DHT production. DHT causes acne. Some modern acne treatments are centred upon reducing DHT on the skin
Varies for people but often when the drug has been used for an extended period your hormones balance and improve.
If I use RU then get a transplant down the line I know that I’ll have to discontinue use for some time so I should expect all my hairs that have been preserved to fall? So would there be a point getting one
No, you won't have to stop that long, only a few weeks at most. Anything you lose in that short term you can get back.
can i ask you please whay are you looking at the side. all afew secondes?
He is reading a note😊
Can I use the RU in Nanoxidil?
Yes, but you actually don't need to if you're using Dslabs DNC-N.
Try to get their Revita Shampoo and Conditioner for best results.
Do you know how long it takes for RU58841 to absorb before washing off? I know minoxidil solution takes up to 90 minutes to absorb before you can wash off and I’m going to mix it with the solution. Am I right to assume it’s dependant of the carrier hence RU would take 90 minutes if mixed with minoxidil solution?
Hey mate, thanks for sharing your experience.
How are you doing these days? Is your research subject still taking the drug?
Any developments? Good or bad?
Just apply at night and sleep on it.
Thanks Kevin, might start RU cause fin isn’t working and I’m still miniaturizing and receding
any results?
@@skidipap8750 didn’t start RU but fin still isn’t really working. Maybe I got a little thicker but hairline got destroyed and so did density
are whiteheads and pimples a sign of acne while using anti androgens like finastride?
It's not related to finasteride. You just need to wash your face more often. I have a video on skin health, check it out.
REPLICEL/SHISEIDO RCH-01 what are your thoughts ? Is a cure possible ? I doubt it, but people have been posting a lot of stuff about it. Video topic ?
Its undergoing phase II clinical trials still as far as I understand. It looks promising but we'll have to wait and see what comes of it.
It wouldn't be the first time an apparent cure has been discovered only to become a fart in the wind so even though I'm optimistic I'm not going to draw any conclusions yet.
Came here cause 5% minox was giving me heart palpitations :(. Would you recommend 2% minox if I don't get heart palpitations? I'm worried that even if I don't feel it it could still effect my heart.
Yes but please talk to your doctor before doing anything.
@@haircafekevin damn you fast! Subscribed! Lol
@@aceace5641 Thanks homie!
What would be the safest way of stacking microneedling and ru . Atm im micro doseing ru at 10-25mgs once a day
Hows it going ?
@@dilrajkhangura3859 tbh i dropped ru i was on it for 8 months and no growth nothing even when i discontinued it there was no shedding nothing basically snake oil for me that is
@@theoneguy13 so what are you doing for your hair atm ?
@@dilrajkhangura3859 dutasteride (mon wed fri) minoxidail (daily) and microneedling (1.5mm once a week)havnt lost any grond in 4 years
No loss but did you gain anything?
What about Minoxidil? I hear some say they get shortness of breath with it.
I do but depends entirely on application time to exercise.
How do you have to store ru? Is it fine to leave it in a drawer?
No, put it in the freezer, lasts much longer.
I think I gave myself a nocebo effect because of the formums stating that heart problems could happen when it's not true and "instantly" got chest pains, used it for 2 weeks and noticed less shedding in the first 2 days and started notice it working.
How'd you store it?
zoo powder In the freezer and k and b solutions in the fridge.
Any issues at this time as far as sides go and is helping in anyway? Thanks
Update?
Hey mate, thanks for sharing your experience.
How are you doing these days? Are you still taking RU58841?
Any new developments to report?
Hello Kevin, have you heard about the forum gossip of the 23 year old who supposedly took 3 doses of RU and developed heart failure? Can you explain how or why this could have happened or maybe address it in a future video?
Chance Robertson this is what scares me also
Do you use ethanol or kbr as your test subjects solvent ?
Usually ethanol based solutions like stemoxydine or alfatradiol.
Kevin, for mild Alopecia areata, will fin and min work? Is there an ideal topical for alopecia areata?
Also, if I get a transplant for the affected area, what's the risk of another AA attack?
Finasteride won't since that specifically treats androgenic alopecia. Minoxidil might though since it is a non specific hair growth agonist. Alopecia areata is pretty rare though. I've seen people who think they have it when it is really just androgenic alopecia so make sure a dermatologist confirms the diagnosis.
@@haircafekevin Got it. Many thanks. I had a transplant surgeon actually do a free consultation and he said the same thing. He said areata is rare and androgenic alopecia is often mistaken as other issues.
I told him a fungal infection/seborrheic dermatitis caused my hair loss. He said that doesn't happen. It's androgens... There just may have been a simultaneous fungal infection present.
how do you get RU58841?
About 3 weeks into using RU 58841 for the research subject, I love it & no sides reported on 10mg 4x/ week, is this generally enough to get hair regrowth/ recovery for diffuse thining of research subject? Or are increases in frequency, dose needed to achieve any regrowth? (Slight dizzy on 20mg once)
10 to 20 mg are the best tolerated doses based on anecdotal reports. Sadly we have no clinical data on RU since it was abandoned during clinical trials so there is no standardized dosing.
@@haircafekevin ok thank you
So do you take this? I am really thinking about buying some.
Yes. He said he used it on his "research subject" at 10-20mg
@@beezowdoodoozoppitybopbopb9488 10 or 20 mg is extremely low dose. That's like 3 droplets lol
@@AristotleofStagira1 with the potential for heart failure, I'd hope you'd err towards dosing too low.
For a person on deca and test, they can not use finasteride or itll make androgenic alopecia worst. Do you know if dosing RU once a day would be enough ? do you know ru's half life and how long it would protect from dht and test in the scalp? do you know since nandrolone (deca) and a 5-ar inhibitor makes hair worse, so far ru and nandrolone(deca) looks like it doesn't make hair loss worst?
It's hard to say, depends on the individual but using RU would certainly be better than doing nothing. Deca without fin is pretty harmless on the scalp so it would depend on how much test you are using.
RU has a short half life, just a few hours I believe but it outright kills androgens on the scalp so it can be used just once daily or even every other day.
Stacking test with deca is a must so RU is a good alternative to finasteride in this case.
@@haircafekevin Thanks for your help, I appreciate you and these videos You're a extremely intelligent guy in regards to androgenic alopecia and so thankful for you
@@JohnSmeton No problem, thanks for watching. Always happy to help.
Creatine and heart size? 🤔
Assuming most people wait until some of these new drugs are FDA approved, are any of the other topicals like (Redensyl,Procapil, Capixyl) worth using in the mean time as an adjunct to topical minoxidil and topical/oral finasteride? There is some initial evidence of effectiveness for a combination of those 3 compared to topical Minoxidil results but I haven’t seen a study reproduce the results.
It couldn't hurt, I find stemoxydine works well as an adjunct growth stimulant to minoxidil since it works differently but there is definitely no growth stimulant I would replace with minox.
I’ve never seen any good review for Redensyl growing hair and believe me I’ve looked, not counting the reviews of companies selling the product because those are always fake
Does hair blowing your hair with cold air before applying RU58841 interrupt the absorption??
Hi Kevin, Im 22 yrs old and a 3 vertex. I've been using fin since march 12th and have been shedding even more which I've read also can be normal. I understand that fin doesn't takeaway all dht on the scalp and testosterone on the scalp also causes hair loss. I haven't had any side effects thankfully. Whats your take on taking fin and RU58841 at the same time? Thanks Kevin
I think that you should hold off and be very patient. Let the finasteride do its job, then asses your hair at the year mark and even the two year mark. It took a good two years before I truly saw the progress from finasteride. That's the not case for everyone. The goal to keep in mind is minimal effect dose. Add things on one at a time so that you're getting the results you're looking for using the least amount of drugs possible. At the two year mark I added minoxidil to my hairline and at the 6 month mark in already making more progress. If it ever stops working then I'll asses and an anti androgen like topical finasteride or maybe something herbal that has shown to help. I.e. saw palmetto. I wouldn't use ru until a last ditch effort.
@@johncole4882 yeah, I think its a little understated how long it actually takes for finasteride to work, I didnt start noticing real results until about a year into it. People talk about like 3-6 months in you should see results, I guess everyone is different.
What IS the data on RU going systemic? Curious
There is no data sadly. Clinical trials on RU were abandoned so most of the data we have to go on is anecdotal. On the bright side there aren't many people who complain of side effects and the ones who have were people using ridiculously large doses, like 100-150 MG per day. Even just 20 MG per day on your research specimen is sufficient.
@@haircafekevin Hi Kevin, great video. For RU would you recommend 20mg a day for my research subject who can't take finasteride?
@@Jordanz0rd yes, 20 mg of RU is what my research specimen responded best to.
My research subject Took ru today for the first time, some heart palp, erection is gone. So ru is not a option. I try cb now on my Research subject. Do you know when the ru is out of the system and how I can recover from the sides?
Fubar
@José José it is 6x I guess
nah it didnt help
yes it does I got chest pains from it its never happened before taking ru and it stopped when I discontinued use.
how much did you use ;for how long ,how long did it take you to recover ?
how much did you use ;for how long ,how long did it take you to recover ?
@@thecanadakid7622 used 1ml and even lowered it to 1/2 a ml when i got sides. chest issues stopped right after i discontinued use and i used for around 5 months.
@@mathieu4069 I got sides from minoxidil and ru and even scalp zits from nizoral so I don’t want to take chances with cb or fin I’m probably predisposed to get sides because my genetics
Hey Kevin, I’m starting on my journey of attempting RU , part of me feels frightened, am I worrying unnecessarily, how have you found it? I’m starting quite low 25mg daily
How is it going with RU58841? Are you experiencing any side effects and how much are you applying?
Hey man, I’ve started, nothing so far, but only a few days in
Started quite low sensibly 20mg daily
st helens villain, Hi I got my RU58841, but was thinking not to use it bcoz I got scared if I get sides, but if I use a small amount like you twice or once a week, would that b ok?
I am on fin+min daily and I take around 25mg of ru on m/w/f never using on my training days been making great gains no need to go mad with ru.
@@YNWA-wr7wu I know someone who uses every 3.5 weeks bi weekly and their shedding has completely halted, I use M/W/F 25mg.
Hey Kevin, thanks for your great content chief! I’m currently 19 years old. And was diagnosed with Male pattern Baldness (blood test was ok) honestly fin and minox and ru are no solution for me. I think the only way I can get mz hair a hair back is a stem cell therapy in combination with a prp. Would you reccomend it? Is there a way I can contact you private? Honestly I’m so desperated and depressed because of my hairloss, it affects me in a very negative way...
Why not just go on fin and minoxidil
If you're truly that desperate, why are you neglecting the only methods that works for hair loss instead of trying them for yourself and seeing whether they work or they don't? Lol.
@@Reloaded9923 fin- side effects, minox- side effects and twice per day for your lifetime is very heavy and it could make your existing hair dependent on that medication
@@bos7791 what side effects of minoxidil? Been taking for years, never had one. Maybe your scalp is itchy And that's it
Hey friend... would you help me telling me where can I get oral minoxidil here in USA... thank you
Its RX only in the USA. You can get it on the grey market but it would be illegal for me to give a source.
Loniten is common on online pharmacies though.
I’ve noticed more sides with minox once a day than RU at 50+ mg a day
Minox is not worth it in my opinion. Yes it makes your hair grow faster but id pick fin + ru over anything else. I take 1mg fin in the morning and at night with biotin(2mg a day). March will be 1 year on fin and it’s definitely saved my ass but I’m greedy and might switch to dutasteride for some time and see what happens. RU nightly for about 5-6 months and I derma roll once a week and skip topicals that day and sometimes the day after. Ketoconozole 2% shampoo every 3 days or so. Also worth mentioning I quit minox cold turkey about 8 months in and didn’t shed that bad.
I buy premixed from anagenic. Really want to start mixing my own soon but haven’t pulled the plug on it yet. Nice that you switched to dut after a year, really considering making the switch. Got a bunch of it sitting in my bathroom that I’m too scared to take aha. Any sides? I never have any from fin 2mg a day so I’d expect not to get any but I know it’s much stronger.
Hard to say how helpful it has been because of other factors. I think the combination of fin + ru works better than either by themselves. My hairline is not amazing but compared to pictures I took a year ago it’s 10x better. Still receded but much thicker than it was headed. Will probably switch to dut after a year and give it a try for at least 6 months or so.
Any side effects from the RU and do think it’s safe for long term use, I don’t want to kill my research subject. Thanks
@@michaels999 is your research subject still alive?
Hi Kevin.
Due to side effects of 10,5 months use of Finasteride (Gyno), I decided to transfer to RU 58841. I ordered 2 bottles of 5% solution and plan to start this week.
1. Is there anything in particular that I should be aware of while using RU, and are there any precautions or protection against development of androgen deficiency side effects or cardiovascular issues ?
2. I have diffuse thinning, so I wonder If you can share your experience about the proper dosage of RU per day? Would 1 ml per day be sufficient against AA?
Thank you for the reply and keep up the good work.
Andrej
Yes updates
@@michaels999 Hello. I have been using RU 58841 on my research subject for almost three and a half months. Two weeks after the introduction of the treatment, I noticed an increased shedding, which lasted for almost 2 months with great intensity. I am now in a state of plateau (without significant loss), and the condition is slowly normalizing. Without visible hair thickening effects so far (Prior to the end of the first six months it would be too early to give an assessment).The strength I use on my research subject varies from 5% solution to 8% solution (the raw powder is mixed with ethanol-PG). No side effects so far. I hope that this info will be helpful.
Andrej Dimovski Thanks
@OMENITOLDYOU Hello, and thanks for sharing. Any assessment of the efficacy of MPB prevention medication before the expiration of the first 6 months of introduction of the treatment would be premature. From my previous experience in the last 19 years using a variety of medications for prevention of MPB, I can confirm that the use of each drug (minoxidil, finasteride, ketoconazole, saw palmetto etc.) has a different effect on each individual. Since I'm not a doctor, I wouldn't allow myself the luxury of making an unsubstantiated claim as to why RU in your case caused side effects in such a short period of time. Taking into account the experience of many users, though it is an experimental substance, in small doses RU has a pretty solid efficiency/side effect free ratio. Relating to your question, the shedding after introducing RU amounted to 30-40 hairs per day over a period of nearly 2 months.
@@andrejdimovski7197 any update?
Hey Kevin, i know you’re not a doctor. My wife got pregnant while I am on finasteride. I only take finasteride twice weekly, but I believe I took one the day she got conceived, what’s your opinion on this? Should I ask the doctor?
Congratulations Jay. I often worry about this as well but from what I've read it's just a precaution. I hope all is well with the baby?
Is it possible to be a non-responder to RU? I used it for over 3 months with no noticeable positive effect. It's legit product too.
I think in the clinical trials there were some who were non responders.
@OMENITOLDYOU perhaps but baldness doesnt normally progress slowly over time. It can come in periodically.
Kevin do u think finasteride can restore receding hairline ? I feels it only stops hair loss
Some people respond extremely well
Especially if you only recently lost the hair
About 33 percent of people get some regrowth from finasteride but I wouldn't expect any miracles like regaining a norwood. I got some regrowth but it was in the areas where I still had hair and the hairline is the area of the scalp which for most people is most sensitive to androgens hence why it goes away first usually.
I would get on finasteride to stop any further loss and then save up for an FUE. An FUE is easily the best decision I have made in my hair loss journey. I went from a Norwood 4 to maybe a Norwood 2 at the very worst.
Am on finas + minox , and thinking going your path of having an fue to restore the hairline but at the same time afraid of the shock loss situation of my existing hair i don’t want them to thin
@@ricoawar4290 Shock loss is rare and even if it happens its temporary, I wouldn't worry much.
Are you still using RU 58841? If so how has it been
Currently, no. Just the classic finasteride+minoxidil stack.
What do you use or recommend for washing your hair in the shower consistently? I use ketoconazole shampoo right now, but I hear it can fry your hair.
Mix some jojoba oil with the ketoconazole shampoo or use it afterwards as a conditioner, it helps counter the dryness.
I'll use a generic variation of head and shoulders typically as my regular shampoo or a coal-tar shampoo every now and then.
Thanks for the videos dude. Can I ask what your current regime is and did you stop taking dutasteride?
I've been on finasteride for 3 months, no sides effects but not much change either. Looking to test out dutasteride.
Thanks
No problem, thanks for watching.
Right now I am just taking finasteride and minoxidil while occasionally using alfatradiol. I have stemoxydine I might cycle in early next year as well to see if I can get any additional regrowth.
I don't take dutasteride although I felt it worked well enough albeit not noticeably any better than finasteride in my case, I just didn't like that is a softgel because I'm vegan.
@@haircafekevin Thanks for the reply! I'm going to go pharmacy today and pick up some dutasteride and give it a try. Did you cycle it with finasteride or just take it individually?
One last thing did you notice any additional shedding switching both to and back.
Thanks
@@themetamind9305 No problem. I used it individually and took it with finasteride daily for several months.
I didn't get any shedding but that's likely because the mechanism of action of the two drugs is similar enough.