Making methylamine HCl but for legal reasons

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  • Опубліковано 18 гру 2024

КОМЕНТАРІ • 735

  • @chemdelic
    @chemdelic  Рік тому +46

    To try everything Brilliant has to offer-free-for a full 30 days, visit brilliant.org/Chemdelic/ . The first 200 of you will get 20% off Brilliant’s annual premium subscription.

    • @eank3429
      @eank3429 Рік тому +5

      Thank God 😊 🙏 I can't wait to use brilliant to expand my chemical knowledge

    • @brettmoore3194
      @brettmoore3194 Рік тому +2

      Is there a ceramic bubbler made so the acid could react in the solution instead of surface only reaction😅

    • @Nero-z7d
      @Nero-z7d Рік тому +1

      Now to combine that lovely smelling stuff with this and end up with something the government doesn't care so much about. I love sharing the empathogen.

    • @savage069
      @savage069 Рік тому +2

      You are two blonde hairs away from a government visit, my dude.

    • @davidjavids2431
      @davidjavids2431 Рік тому +1

      OMNIPOTENT LOVE TO EVERYONE GLOBALLY
      MEDITATION REQUIRED BREATHING CORRECTLY VITAL AND
      MANIFEST AND COMMUNICATE

  • @DuckPerc
    @DuckPerc Рік тому +685

    Seeing the garage doors in the glassware really brings it all together.

    • @mrnice4434
      @mrnice4434 Рік тому +31

      Good think he is not in a camper :)

    • @Trump2024asw
      @Trump2024asw Рік тому +7

      Seeing those doors earned this sub.

    • @natebender4740
      @natebender4740 Рік тому +3

      Gotta start somewhere!

    • @cannack
      @cannack Рік тому +10

      open the door up 2 feet, add a large fan = Hillbilly Fume Hood

    • @NoahBenzing-ru5st
      @NoahBenzing-ru5st Рік тому

      Lies! Your two dads won't let you get online alone!

  • @That_Chemist
    @That_Chemist Рік тому +422

    that 'distillation' is one of the undergrad moments of all time

    • @iuristasiv9360
      @iuristasiv9360 Рік тому +13

      😂😂😂

    • @chemdelic
      @chemdelic  Рік тому +58

      LOL

    • @computerkiller1494
      @computerkiller1494 Рік тому +5

      Gotta pay for college

    • @BillAnt
      @BillAnt Рік тому +6

      ​@@chemdelic- I read somewhere that Methylamine can also be synthesized using formaldehyde and ammonium chloride, then converted to its base using sodium hydroxide. Not sure about yields, what's your thoughts about it?

    • @4b5urd.
      @4b5urd. Рік тому +21

      @@BillAnt I wont say its the better way to do it but, its easier, cleaner, simpler, straight forward and no question if the reaction has worked, and yields a shit ton more than what was yielded here. To say it is multitudes more efficient and easier to do.
      A few tips for anyone who will actually run the reaction
      Note that the temp you reflux at is critical in that reaction. 104C is what is most often suggested. If your temps go higher, you risk making more dimethylamine and trimethylamine.
      Instead of ammonium chloride and formaldehyde, which some poeple may not have available, you can use hexamine fuel tablets which you can find in most sporting goods stores or camping/outdoors section of big department stores and hydrochloric acid. The acid decomposes the hexamine into, you guessed it, ammonium chloride and formaldehyde. Convenient huh?

  • @MikeyMobes
    @MikeyMobes Рік тому +224

    27% yield is good without a proper schlenk line setup. In the world of inorganic synthesis thats a solid yield. All that smoke and fog is your hygroscopic reagents reacting with water lowering your yield. Nice work!

    • @ashe1.070
      @ashe1.070 Рік тому +12

      An inert atmosphere is not necessary for a dissolving metal reduction like this one. Also nothing in this reaction is reactive towards water. There are only three reagents: granulated tin metal, 31.45% hydrochloric acid, and nitromethane. That hydrochloric acid is 68.55% water. Those white fumes are from the reaction of MeHN2 and HCl in the gas phase forming a bunch of very small particles of MeNH2•HCl. Like the fumes produced in the reaction of ammonia with HCl (or really any volatile acid)

    • @Nathan-ny7kh
      @Nathan-ny7kh Рік тому

      WRONG!!! All that smoke is from the reagents doing magic, I thought that was pretty obvious

    • @blackhole3298
      @blackhole3298 Рік тому +7

      @@ashe1.070 I think he lost yield in his gas-capture setup, plus some of it might get captured by the tin itself, if that amine coordinates with one tin or possible two tin atoms, it won't leave the solution.

    • @ashe1.070
      @ashe1.070 Рік тому

      @@blackhole3298 Definitely. There was a lot wrong with the gas absorption step. It would have been better if he used a glass tube, and had cooled the beaker in an ice bath. I also did some stoichiometric calculations:
      MeNO2 + 3 Sn +6 HCl ----> MeNH2 + 3 SnCl2 + 2 H2O
      He used 0.27 mol nitromethane, but only used 0.38 mol tin metal. He needed to use at least 0.81 mol tin for all of the nitromethane to be reduced. Though an excess of tin would be best. I didn't calculate the moles of the hydrochloric acid, but judging by the amount of tin left over there definitely wasn't enough. Also, when I used this reaction to reduce nitrobenzene, 2-nitrotoluene, and dinitrobenzene it took a lot longer than 1 hour. So, its possible he didn't reflux for long enough as well. If I remember correctly, the reaction should be continued until all of the tin has reacted. If there is no more tin metal, and the solution is strongly acidic the amine will be in the form of the HCl salt, and can't coordinate with any metals.

    • @Oogabooga2231
      @Oogabooga2231 6 місяців тому

      Wtfff how you know 😑😑😑

  • @LabCoatz_Science
    @LabCoatz_Science Рік тому +213

    Excellent video! Now all I'm left to wonder is how the hell you got Brilliant to sponsor a List 1 precursor synth, lol. Great content, keep it up man!

    • @chemdelic
      @chemdelic  Рік тому +55

      They are just that good of a sponsor!

    • @seankessens5148
      @seankessens5148 Рік тому +5

      Because it's not illegal it's chemistry and only a schedule 1 precursor if using it with intent to manufacture drugs which he's not doing

    • @farmboy3632
      @farmboy3632 Рік тому +1

      His intent is to fish for likes, your honour

    • @chemdelic
      @chemdelic  11 місяців тому +3

      I mean its also really useful in chemistry too (but also yes for likes💀💀) @@farmboy3632

  • @geekst0rm87
    @geekst0rm87 Рік тому +140

    Instead of using a funnel in the HCl try using a small glass tube. Bubbles would be smaller and provide more surface area for the gas to react.

    • @CloudCuckooKing
      @CloudCuckooKing Рік тому +15

      That's what I was thinking. The funnel's a good jury rigged antisuckback, and it beats the hell out of nothing for stopping small quantities of dangerous things, but it looked to me like the output was overwhelming it.

    • @That_Chemist
      @That_Chemist Рік тому +21

      You can also use those fish tank bubblers or the sucky thing that the dentist uses for a much better experience

    • @WaffleStaffel
      @WaffleStaffel Рік тому +6

      Adding a small aquarium air pump to the "circuit" will prevent suckback. I think E&F detailed this in one of his videos. I use one of those tiny ultrasonic ones. Then you can use a capillary, or even fritted or stainless airstone.

    • @mkimball6
      @mkimball6 Рік тому +5

      Yeah, you'd rather have a deep solution and small bubbles. A tube or pipette into a grad cylinder would be much better. A gas washing bottle with a frit is ideal. With the funnel you should stir the solution, so that the top doesn't become saturated

    • @dmoskva
      @dmoskva Рік тому +5

      Guys, the simplest answer is to use gravity to your advantage. By adding a height difference between reaction vessel and product vessel, you can use the head pressure to prevent pull back. You can loop the tube downstream to increase pressure if needed. But definitely remove the funnel from the end. You ended up losing a lot of yield there. IMO medium stirring of the acid and a glass straw on the end of the tube inserted into the bottom corner of the beaker should increase available contact area for reaction.

  • @Amipotsophspond
    @Amipotsophspond Рік тому +105

    when smelling something you should wave the smell over to you, that way if it knocks you out you don't fall on the lab gear. also you lower the amount that gets to you so the cancer probability is less. it was good that you did not hold the bottle.

    • @LuxGamer16
      @LuxGamer16 Рік тому +46

      That's like basic chemistry safety

    • @alext552
      @alext552 Рік тому +3

      we were taught this in high school, but ive never seen anyone do this in a real lab setting

    • @W1nstorm
      @W1nstorm Рік тому +1

      🚨🤓

    • @jaimeortega4940
      @jaimeortega4940 Рік тому +7

      Please don't smell any reactions in the future! Had to many friends of mine have problems from this plus from doing this. From what I hear methylamine is none too pleasant smell.🐽

    • @alext552
      @alext552 Рік тому

      @@jaimeortega4940 with the vast amount of organic solvents i have huffed in my time in the lab, i think its already over for me

  • @Gunbudder
    @Gunbudder Рік тому +191

    this reminds me of taking chem in school. at the end of the year i realized my chem professor had taught the entire class about making meth. every unit focused around one of the steps of production for meth, but was focused on teaching the chemistry. he never acknowledged it and just laughed when i asked him about it later

    • @interstellarsurfer
      @interstellarsurfer Рік тому +82

      Student loan status: Paid.

    • @bdugh
      @bdugh Рік тому +42

      My high school chemistry teacher did basicly the same thing but for lsd.

    • @Trump2024asw
      @Trump2024asw Рік тому +13

      Would you say Chem class is worth it? Or would you better recommend engineering? Chem engineering? Ty an God bless.

    • @dingoweasel
      @dingoweasel Рік тому

      chemistry is less math and more fun than chemical engineering, but chemical engineering is all about paying those bills
      @@Trump2024asw

    • @dipf7705
      @dipf7705 Рік тому +6

      ​@@Trump2024aswboth. Or the one you like

  • @steceymorgan814
    @steceymorgan814 11 місяців тому +202

    Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.

    • @APOLLINAIREBARTHOLOMIEU
      @APOLLINAIREBARTHOLOMIEU 11 місяців тому +1

      Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!

    • @elizabethwilliams6651
      @elizabethwilliams6651 11 місяців тому

      Yes, dr.sporesss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.

    • @Jennifer-bw7ku
      @Jennifer-bw7ku 11 місяців тому

      I wish they were readily available in my place.
      Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac.
      He's constantly talking about killing someone.
      He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.

    • @APOLLINAIREBARTHOLOMIEU
      @APOLLINAIREBARTHOLOMIEU 11 місяців тому

      Is he on instagram?

    • @elizabethwilliams6651
      @elizabethwilliams6651 11 місяців тому

      Yes he is. dr.sporesss

  • @JonnyMack33
    @JonnyMack33 Рік тому +13

    I used to work at chemical plant as an apprentice and I've never been more fascinated in my entire life! I was lucky to work up from a cleaner in just about 7 months, I'm not an idiot and I was obviously interested so they gave me a chance. I was lucky to work in a plant that was a "problem solver" so we there were only a few products that we did over repeatedly, one was refining oil for a Chinese company that was an anti-knocking compound. It was £1000/Ltr so we had to be careful. I didn't do any additions/reactions at that point, just dis/charging filters and drying in all sorts of impellor dryers and a kind of spin dryer. I loved it but my back gave out so had to quit. I really miss it, and could've punched myself for not doing better at school.

  • @masongauthier1998
    @masongauthier1998 Рік тому +8

    Just came across your channel while looking for an extraction tec for something totally different. And this is the best kind of chemistry videos on UA-cam man keep her up 🤘 got a lifetime subscription here today.

  • @rdizzy1
    @rdizzy1 Рік тому +33

    The main reason these street drugs kill people purely has to do with them being illegal (as most deaths are caused by unknown purities and unknown other chemicals added to the drugs, as well as violence surrounding the illegal sales). The deaths involved almost never have to do with the pure form of the chemical itself, but a deranged, toxin filled shitty street version of the chemical. If these drugs were legal, and regulated, people would know the doses they were consuming, know the drugs were pure, and there would be far less violence associated with illegal sales and use. (Also less wasted on EMTs, less wasted on cops, less wasted on holding people in prisons for possession, all of this could go into free drug rehab centers instead) Decriminalization isn't enough, as it only solves half the issue, considering that people will always use drugs, they really need to be fully legalized and regulated. (Like cannabis, tobacco and alcohol)
    People don't truly care about deaths, harms and costs to taxpayers though, because if they did, it would be legal already, what people truly care about is the puritanical punishment of those they subjectively deem to be morally inept.

    • @AricRoy
      @AricRoy Рік тому +1

      Well stated & too true! The fact is there are "legal & pure" versions of most street drugs available with a prescription & produced from Big pharma. In the case of meth, look no further then Adderall. And just as you have pointed out, when regulated and produced in clean-room environments the socalled lethal side effects of the street versions are almost if not entirely eliminated. And governments around the world have known about this for years or even decades with the case in point being Japan pre-World war 2 having given entire cities large doses of meth (the og recipe) and methodically documenting the effects with them being minimal to almost non-existent over a substantial period Of time.

    • @neepsmcfly4176
      @neepsmcfly4176 Рік тому

      Yeah, it's a bummer. The ball got rolling w Carter but Reagan really doubled down. No social science, no evals. Then privatizing prisons kinda sealed the deal, I think. Though, even without that, the narrative alone made for a convincing way to reinforce racist ideology and therefore removable only under an act of a race traitor god. Depressing to recall it all. And side effect (woohoo!) was the whole social mentality of criminalizing, thereby sabotaging every productive monetary policy by overfilling prisons and courts. All the while, smart northern euro countries actually study a bit and take a risk treating dependency as health issue vs criminal.... and, BINGO! Hopefully young generations are paying attention and researching their HX.

    • @rdizzy1
      @rdizzy1 Рік тому +9

      @@jamisonr The amount of drug users does not change in any meaningful way after legalization. No non drug addict is going to suddenly smoke some crack or shoot up some heroin just because it became legal. Drug users use drugs regardless of the law, and they will always do so continuously, over and over. None of those areas have legalized drugs, decriminalization isn't enough to help anything.

    • @neepsmcfly4176
      @neepsmcfly4176 Рік тому

      @@jamisonr yeah, I've seen the devastation but I think you should read up on the kinda impact it has on an addict when treated w dignity. You may be right about our society not being ready but I'm convinced it's mainly bc of mindsets similar to yours. Not attacking or being hostile. Just saying that even ignoring all the promising social experiments in Europe, we've been doing our little experiment over here & all it's done is bankrupt us, increase entrenched social racism, overcrowd prisons, create social & political burdens when no one hires them, until the eventual increased recidivism. I believe we can confidently say that over 50 years we've accrued enough data and, well, I know change is hard but it's pretty clear the whole dehumanizing thing is a big fat failure. Imo, our society could do w a little sympathetic assistance. It feels a whole lot better than excitedly waiting for your opportunity to legally shoot someone.
      Nevertheless, it's stupid to continue a failed policy so where's the ideas? Also, I wasn't actually recommending we ignore the data gathering across the pond.
      I mean, really, are we so far gone in our violent bloodlust orgy that rerouting some incarceration funds into actually functional rehab clinics is just too ludicrous for contemplation?

    • @aspersiondetergent5673
      @aspersiondetergent5673 6 місяців тому

      @@jamisonra number of European countries manage to do it quite well. There is definitely more going on here and it saddens me to see the ball being fumbled so hard.

  • @jamessunderlandseventh7410
    @jamessunderlandseventh7410 Рік тому +57

    It's way better to use Tin powder instead of Tin pellets for that reaction.

    • @Daveeeeeeyhowyoudoing
      @Daveeeeeeyhowyoudoing Рік тому +2

      You watched breaking bad, didn't you 😂

    • @DrSpooglemon
      @DrSpooglemon Рік тому +19

      @@Daveeeeeeyhowyoudoing They didn't make methylamine on Breaking Bad - they stole it!

    • @poindextertunes
      @poindextertunes Рік тому +1

      @@DrSpooglemonmy buddy and his friend stole a farmers tank of it and buried it underground with a spout sticking out so they could use it as they pleased 😅

    • @ArrBee1
      @ArrBee1 Рік тому

      Greater surface area, no?

    • @dripdatglass
      @dripdatglass Рік тому

      Dude fr not so brilliant, and even illegal amigos know that 1

  • @christopherleubner6633
    @christopherleubner6633 Рік тому +18

    The easiest reaction is with formaldehyde combined with ammonium chloride and reflux it for a while. Make sure the ammonium chloride is in 2x molar excess and you will get nearly pure methylamine as your product with some ammonium chloride that will crystalize out of the concentrated methylamine. If you want dimethylamine instead simply use a 2:1 molar ratio of formaldehyde to ammonium chloride.

  • @TheNativeNation
    @TheNativeNation Рік тому +11

    Always love seeing these uploads!

  • @LenKusov
    @LenKusov Рік тому +6

    SWIM says that the best way to get a good absorption with the "distillation" here is to use an aquarium bubbler stone, one of the big long ones, at the bottom of a jar mostly full of glass marbles or those weird ornamental glass pebbles they sell at craft stores. That breaks everything up into super small bubbles, generates plenty of turbulence, and slows the bubbles down enough to SIGNIFICANTLY increase yield. When SWIM was concentrating ammonia for making touch powder, that worked really well.

    • @chemdelic
      @chemdelic  Рік тому +3

      Interesting. Thank you for the advice :)

    • @LenKusov
      @LenKusov Рік тому +2

      @@chemdelic Also if whatever you're making is trying to eat whatever binder is in the bubbler stones or the plastic hose barb or the hose itself, you can make a decent equivalent by crimping off the end of a glass tube (aka the $5 packs of glass drinking straws) and filing a bunch of tiny slits in it. Alternately you can mix some water glass into sand so it sticks together, lump it on the end of the glass tube, and sinter it with a mapp torch to make a chemical resistant bubble stone once you wash out the sodium silicate leftovers.

  • @orlandodattoma6678
    @orlandodattoma6678 Рік тому +25

    To increase the yield in the free base methylamine removal step you should try using a glass aquarium bubbler with a sintered septum inside a graduated cylinder (super cheap), or better still a proper gas scrab bottle.

    • @chrisfowler1005
      @chrisfowler1005 Рік тому

      Clever idea

    • @warrenmccarty256
      @warrenmccarty256 Рік тому +2

      I really need that I have a medical condition it seems like every night around midnight I close my eyes and go off to some other realm and I'm suddenly Jarred back into this realm at around 7:00 in the morning and as long as I got plenty of this stuff that never happens

  • @koukouzee2923
    @koukouzee2923 Рік тому +586

    Bro really pushing it with the government

    • @nevinrush2553
      @nevinrush2553 Рік тому

      Fuck gubberment

    • @koukouzee2923
      @koukouzee2923 Рік тому

      @@williamackerson_chemist iam talking about all the things he does
      When combined together they sound sketchy

    • @tweadz9846
      @tweadz9846 Рік тому

      @@williamackerson_chemist i think this comment just put all of the viewers on a list

    • @abundantharmony
      @abundantharmony Рік тому

      @@williamackerson_chemist how

    • @_caracalla_
      @_caracalla_ Рік тому

      @@williamackerson_chemist for purely scientific reasons right?

  • @HAL_9001
    @HAL_9001 Рік тому +17

    My dog, Jessie, woke up and walked over to me at the beginning of your video. She hasn't done that since I was watching the Bald Science Man show. 😂

    • @frogz
      @frogz Рік тому +9

      jessie knows it is time to cook

  • @Send-It710
    @Send-It710 Рік тому +4

    Not sure if anyone ever told you this but if you are cooking spaghetti you should use a fish stone air bubbler it increases the surface area allowing more surface for the sauce to adhere to.

  • @jaapgroeneveldt4703
    @jaapgroeneveldt4703 Рік тому +7

    I have got a weird idea for better yield in bubbling the gas in the liquid, it seems like the gas doesn't have enough surface area reacting with the liquid. So why not use a aquarium air stone to make the bubbles smaller and thus making a lot more surface area? The stone should be mostly inert in most reactions.

  • @rafaelmacias9979
    @rafaelmacias9979 2 місяці тому +2

    It has been an honor being on a watchlist now

  • @Amipotsophspond
    @Amipotsophspond Рік тому +2

    so like at 4:22 after you made it cold why did you not decant or filter? is the tin and tin chloride useful perhaps you could go threw the reaction more so I understand. so like 5:47 the point to expose the gas to the liquid HCL so rather then a wide funnel how about a glass tube and a long tube to hold the liquid that way when it bubbles out it has a lot of liquid to travel threw, the gas will coat the inside walls of the bubble and as the bubble lifts up new liquid will replace those walls, if you wanted you could cap the liquid containing tube and run the gas coming off of that threw another tube of the liquid. some times you can find cheap gas filtration tubes sold as water pipes for smoking local herbs, depending on the state you are in these water pipes might be called "bongs". they are usually made from borosilicate glass as they are use to dealing with heat, so they should work as normal lab glass. perhaps the gas does not have enough pressure coming off of the reaction. I wonder if you could increase the pressure using a U pipe with the reaction mostly happening on one side of the U while every now and then you increase the pressure to the other side of the U to push a bubble threw, in a batch.

  • @Pro_Triforcer
    @Pro_Triforcer Рік тому +4

    1:43
    They were probably using powdered metal instead of beads, which would have much more surface area and react faster

  • @Loooooorenz
    @Loooooorenz Рік тому +11

    Maybe you can use one of those stones which were used to bubble air into aquariums so the gas is finely spread when bubbling in the HCl. So you can get a bigger reaction surface and more product

    • @geekst0rm87
      @geekst0rm87 Рік тому +4

      The stone would dissolve in the HCl.

    • @markedis5902
      @markedis5902 Рік тому +4

      There are ceramic stones available for just this sort of thing

    • @Moritz___
      @Moritz___ Рік тому

      Mine didnt dissolve when i bubbled air through hcl for a few days. Was bought used so idk what it was made if but looked and felt like some sort of stone

    • @AllGoodOutside
      @AllGoodOutside Рік тому

      Or he could be an asshole and remind you mockingbirds that 20 other people already sang that tune

  • @noreezy4991
    @noreezy4991 9 місяців тому +1

    you should be driving the methylamine by sparging the reaction mixture with a needle, with an inert carrier gas like N2 or argon, and the exhaust being cannulated into the receiving flask.
    basically:
    the reaction flask is sealed with a septum
    Ideally, gas is introduced into the septum sealed reaction flask using a long laboratory needle to pierce it (long enough to pierce the septum and descend all the way down to the reaction mixture so that the needle is partially submerged in the solution)
    You then connect this flask to the receiving flask with a cannula (a 12-24" long 2-ended stainless steel needle puncturing the septum of the reaction flask, but above the solution to allow the atmosphere in the flask to be pushed in passively, by the pressure from the in-bubbling N2)
    The other end of the cannula is submerged in the receiving flask acid, where the total system pressure from the inflowing gas will bubble out through the acid after first evolving the methylamine in the reaction flask.
    You can think of it like "degassing methylamine" in the same mechanism that you would "Degass oxygen" from a mildly oxygen sensitive reaction (For real oxygen sensitive reactions, you want to use "Freeze Pump Thaw", which requires a shallow dewar and a "hard vacuum" - which in O-chem means a "rough pump" like a Welch duo seal)
    in this way you would neither require a reduce atmosphere nor high heat to drive the methylamine out.
    Each little incremental element of introduced N2 or Ar contains zero partial pressure of methylamine, and the system will evolve metylamine from the solution to try to reach the equilibrium determined by the temperature and pressure..... This might not even be that much methylamine evolving for each small amount of gas, but the process is a "continuous flow" type, so even if each little differential mass flowed through the solution only causes a tiny amount of methylamine to come to equilibrium, the same process is repeated continuously until "all" of the mthylamine has been removed from the reaction mixture (in practice its very hard or impossible to quantitatively remove all of the methylamine in this way, but its by far the best method)
    in fact, there may even be a way to run this reaction in a continuous flow process. by constant addition of the reagents. Even if the reaction is never operated at conditions that would produce a high yield if it were operated in batch, the abilioty to continuously drive out produced methylamine would probably make it more economical.
    this is exactly the type of process that would be performed continuously in an industrial operation.

  • @michaelmancuso8900
    @michaelmancuso8900 Рік тому +1

    The reason for the small yield and so much biproduct is while cooling the beaker it must be rotated slowly. Theoretically the liquid would just stay in the same position as the beaker spins but technically it’s turning into a solid so as it cools and becomes more dense it needs to roll away from the other chemicals it is separating from. Also quite a bit of the biproduct sitting on top can be purified and baked down for a less pure but much larger yield aside from what you already have, from what I saw looked to be about 2 to 4 grams but I didn’t pay attention to the measurements so not exact estimate. Hope that helps I was scrolling and was intrigued by some of the stuff you were doing and couldn’t help but check this one out. I was quite a good chemist until I got into a bad car accident, suffering brain damage but chemistry is still one of my favorite things.

  • @bryce4359
    @bryce4359 3 місяці тому +2

    Hexamine fuel tablets work as well if you're looking for a more OTC route

  • @Baron_von_Fargone
    @Baron_von_Fargone Рік тому +3

    Followed this procedure step by step in my kitchen using my hobs oven and microwave oven ,i allso have butane and some other stuff in pressurised cans. .im not sure what reaction i conjured up but ive just woke up on my front lawn ,all of my clothes have turned black,i can smell a gassy eggy smell ,my hair has gone....my ears are ringing and i can hear sirens.... Thoughts 🤔

  • @KleinLuzi
    @KleinLuzi Рік тому +6

    i think there was a lot of Methylamine vapors escaping from your inverted funnel trap. May result in a higher yield to use a system with a fish tank air bubbler or simelar to increase contact area of the gas to the HCl.

  • @gadamgr1227
    @gadamgr1227 10 місяців тому +1

    min 6:05 im not realy sure what is that gas/vapor. BUT its probably methylamine hcl. before you turned the heating CHL from the hydrochloric acid escaped and went through the funnel and formed methylamine hcl! I hope that helped you!

  • @11ride4life
    @11ride4life Рік тому +3

    My new favorite chem channel!!

  • @ArChemistry124
    @ArChemistry124 10 місяців тому +2

    I think you can just use organic solvents such as DCM to get the methylamine out of the solution after adding NaOH, as the basic methylamine is soluble in DCM. And after separating the oraganic layer, just bubble some HCl gas into the DCM and you'll get Methylamine HCl salt precipitate out with better quality

  • @markmcgoveran6811
    @markmcgoveran6811 Рік тому +3

    If I was you I would be quiet about being able to make that because you are pretty valuable if you can do it. I know a guy that claimed they brought five gallons of that to a plant he worked at. He said they had nothing else but guards and guns

  • @thelispinglizard5458
    @thelispinglizard5458 Рік тому +39

    Cant wait for the "feds raided my house" vid.

    • @szmryb
      @szmryb Рік тому +3

      federal prison vlog

  • @curedham2963
    @curedham2963 Рік тому +4

    I know absolutely nothing about chemistry but i find it very interesting, especially this video. Looks like a lot is going on.

    • @logan4856
      @logan4856 11 місяців тому

      Same
      Here lol😊

  • @09FoxRider
    @09FoxRider Рік тому +2

    You should TLC your reactions mixtures. This will give a great understanding of your product development. Also your final reaction for yield should be higher toughly

  • @s0kulite
    @s0kulite 8 місяців тому +1

    Excellent production, Bravo Vince!

  • @Psychx_
    @Psychx_ Рік тому +3

    The white vapor forming upon the gas bubbling through the acid, is your Methylamine HCL salt. It looks a lot like the formation of ammonium chloride from NH3 and HCL. A lot of the microcrystalline salt escaped in the form of these fumes, so next time you may want to use a proper gas bubbler to catch the majority, as the funnel trap is highly ineffective here.

    • @realryder2626
      @realryder2626 Рік тому

      I think he was trolling..? Just either not mentioning it or testing people. What is this stuff anyway

    • @Psychx_
      @Psychx_ Рік тому +3

      @@realryder2626 It's a super useful chemical that's used to create many different compounds, unfortunately also illicit ones.
      Among other stuff, It allows you to introduce mono-methylated aminogroups into molecules, i.e. in a condensation reaction.
      Just taking an amine and trying to stick methyl groups onto it, usually just saturates the nitrogen with substituends, making the methylamine route necessary in the first place.

    • @realryder2626
      @realryder2626 Рік тому

      @@Psychx_ so just remove the nitrogen with an alkylinic process. Ok got it

    • @realryder2626
      @realryder2626 Рік тому

      @@Psychx_ lithium has entered the chat

    • @realryder2626
      @realryder2626 Рік тому +1

      @@Psychx_ brb my trailer park on fire

  • @AdamSteidl
    @AdamSteidl Рік тому +3

    Perhaps you'd get a higher yield if the bubbles of product spent a little more time in contact with the HCl solution, and if the bubbles had more surface area (were smaller bubbles).

  • @IkePegsMarth
    @IkePegsMarth Рік тому +5

    “Check out my new master class on how to make a 10,000% profit with chemistry over at Brilliant”

  • @moztron3754
    @moztron3754 3 місяці тому +2

    is there a chemical that dissolves the stirbar? :D

  • @mythics791
    @mythics791 Рік тому +2

    Very well put together very enjoyable to watch thank you

  • @again5t.your53lf6
    @again5t.your53lf6 Рік тому +1

    Pretty sure you could add to efficiency with using a larger diameter needle for bubbling the Methylamine into solution, you could also do that in multiple degassing stages

  • @mevansthechemist
    @mevansthechemist Рік тому +1

    Isn’t it funny that the crude reaction mixture contained methylamine and HCl, but you had to neutralize it, distill it, and put it back in HCl to isolate it? Chemistry’s a pain sometimes.
    Just my two cents, but I might’ve re-checked the pH halfway through the distillation to make sure it hadn’t gone acidic. The wisps you saw on the hot side were probably MeNH3Cl, a bunch of which was left in the reaction flask. You might’ve been able to stir that stuff with NaOH and re-distill to pull out more methylamine.

  • @highlander723
    @highlander723 Рік тому +1

    3:10 You sir have captured How I felt during my entire graduate chemistry career.

  • @darshan.sbps-1018
    @darshan.sbps-1018 Рік тому +7

    Tip : Use more HCL to dissolve the methyl amine and increase the surface area of the funnel next time😅

  • @kelvinpino4065
    @kelvinpino4065 Рік тому +5

    Curiously, methylamine is kida easy to make, (as we just seen) but in the series they show it like a hell to obtain, even they say it costs around 15000$ a gallon

    • @herrbrahms
      @herrbrahms Рік тому +3

      For the purposes of the show, they focused on methylamine as the difficult precursor for P2P when it's really phenylacetone. They didn't want to provide a tweaker roadmap.

    • @linuxguy1199
      @linuxguy1199 Рік тому +1

      Most of the science in the show was bullshit, a good example is when they made the battery to start the RV, that battery would have *never* provided nearly enough current to start an RV. It may have done an amp, but a starter motor needs a few hundred amps.

    • @kelvinpino4065
      @kelvinpino4065 Рік тому

      @@herrbrahms they actually did, in the website organic reactions is the procedure that ww used to turn phenylacetic acid into P2P using thorium oxide as catalyst

    • @kelvinpino4065
      @kelvinpino4065 Рік тому

      @@linuxguy1199 not at all, they actually showed a starting point for any curious amateur chemist with a connection to internet

  • @samwise3342
    @samwise3342 16 днів тому

    Leans over and sniffs unknown chemicals and gases. Brilliant indeed

  • @poindextertunes
    @poindextertunes Рік тому +2

    My dad used to cook in the 60s. His method I would assume was the one that used ephedrine or pseudoephedrine. That good ole biker crank lol

  • @JesseSep.
    @JesseSep. Рік тому +4

    The smell description actually made me laugh out loud

  • @piggogamin
    @piggogamin 11 місяців тому

    Thank you for this educational video. Beautifully simple steps and beginner friendly.

  • @1998flash
    @1998flash Рік тому +4

    I love thiis channel, at this point i just burst out laughing at each upload.

  • @michelb7123
    @michelb7123 6 місяців тому

    Thanks

    • @chemdelic
      @chemdelic  6 місяців тому

      Thank you so much :)

  • @petkotzvetkov6528
    @petkotzvetkov6528 Рік тому +1

    The fumes are inpure methylamine, so are the coating of yellow in the middle of the reaction (of the flask!) is also impure methylamine IMHO..

  • @whatever_12
    @whatever_12 Рік тому +1

    The cartel "Write that down josè and get me his address"

  • @Salaammypeoples
    @Salaammypeoples 11 місяців тому

    Please can you help me. Ive been on prescribed diazepam for nearly a decade and it terrible. Thr doctor wont change it to anything else 😢
    Could you please show me a way to get hold of these other alternatives. Thank-you

  • @keksiiiiii
    @keksiiiiii Рік тому +2

    I love that you arent weaing any PPE apart from gloves lmao

  • @RanishSewak
    @RanishSewak 2 дні тому

    When you said i first started pouring when the stuff tured yellow before smelling it what solutions did you pour sir

  • @yorkshirechemist
    @yorkshirechemist Рік тому +2

    nicely done - not seen this method done before, the one that's more typically used is the 100+ year old, rather inefficient formaldehyde/ammonium chloride method
    I did have an idea for alternative workup step, based on an unrelated reaction involving amines I carried out recently: after the reaction is complete, remove as much of the solvent as possible, redissolve the residue in 25% caustic soda, extract your free-base methylamine with isopropyl alcohol (which is immiscible with highly concentrated salt solutions), then acidify the extract and dry it by vacuum distillation
    might be worth a punt
    (the reaction I used this for was the reduction of amino acids to their analogous alcohols, using sodium borohydride and iodine - I got the method from DOI 10.1021/jo00065a020)
    also, I was always under the impression that dissolving metal reductions were radical reactions, so that ionic mechanism raised an eyebrow for sure

  • @AzidationsAnonymous
    @AzidationsAnonymous Рік тому

    Absolute madlad putting a Rhodium archive reference

  • @NikOthman
    @NikOthman 8 місяців тому +1

    Hi can you please make synthesis of Acetophenone using friedle craft acylation reaction for educational purpose only 🙏Thank you so much more power

  • @abundantharmony
    @abundantharmony Рік тому +7

    "IT'S CLEFAIRY!"
    It's meth.
    "WHAT!?"

  • @FlushingStatic
    @FlushingStatic Рік тому +1

    I love chemistry, can u do 1 on taking out (extracting) the mitragynine and 7-OH-Mitragynine out of krarom "tea" powder,leaves.

    • @chemdelic
      @chemdelic  Рік тому +1

      I tried that before, got a sticky product, but failed to get the pure isolated product. I will have to try again in the future

  • @quinton3997
    @quinton3997 Рік тому +1

    What metal are you useing from what I understand silver is what is needed

  • @justinlandry7474
    @justinlandry7474 11 місяців тому

    So you wondered about your yield. Not sure if this has been mentioned but the Vogel reference doesn't make sense to me. 40% azeotrope THEN gas? I'd think the gas comes first but let's assume it all comes over as the azeotrope. I think the math roughly works out to 20 ml to collect .25 moles or about 7.5ish grams methylamine. Did you check vapor production with litmus before you stopped collecting?

  • @ThorSten-x4q
    @ThorSten-x4q Рік тому +1

    Is it possible to make a solution of 40% Methylamine and water with this Methylamine HCL?

  • @bedlaskybedla6361
    @bedlaskybedla6361 Рік тому

    That white smoke is methylammonium chloride aerosol. Similar think happens when gaseous ammonia reacts with HCl.

  • @randonaut
    @randonaut Рік тому +1

    Nilered but the intrusive thoughts win

  • @mariekefurniere
    @mariekefurniere 5 місяців тому

    What exactly happens at 5:10 ? What are you adding there and if important, how much? TNX

  • @Anilinequeen
    @Anilinequeen Рік тому +1

    The wizardly swirl is the most fun part of being in a lab

  • @4b5urd.
    @4b5urd. Рік тому

    Was this a reaction you've wanted to do? It is a lot more practical to make methylamine hcl by ammonium chloride and formaldehyde. It is easier to do and the yield is multitudes greater than using nitromethane.
    You can also just use hexamine fuel tablets and hydrochloric acid. The hexamine decomposes to ammonium chloride and formaldehyde, then they do their thing and reaction proceeds as normal
    If you've looked at the reaction I'm sure you are aware of this but for anyone else, reflux temp is critical in this reaction. Anything over 104C and you start to produce more dimethylamine and trimethylamine.

  • @singularsquids5753
    @singularsquids5753 Рік тому

    On March 18th of last year, my friend got some Molly. Did a bunch of lines. Then didn’t sleep for two days, and that’s when I realized what I had actually just done

  • @lachlan1971
    @lachlan1971 Рік тому +1

    I'm surprised the hcl solution didn't get sucked back up into the funnel and tube.

  • @nola504creole5
    @nola504creole5 Рік тому +1

    What is that used for

  • @phreezethaking9782
    @phreezethaking9782 9 місяців тому

    Could the loss be it was pushing over in puffs escaping without touching enough acid?

  • @MPF5856
    @MPF5856 Місяць тому

    you can also make methylamine by ammonolysis reaction of chloromethane with ammonia

  • @edwardjohnson1226
    @edwardjohnson1226 Рік тому +1

    I’m curious what legal reasons are there for this? I’m a young chemist myself and I’m interested in learning more, can I get a sample too see if my even close to yours please 🙏 it would be really helpful to me . Happy holidays to you and your family

    • @vadaza
      @vadaza Рік тому

      Hey I'll refer you to this mate that sells them, he's reliable and discreet.copped from him couples of times

    • @vadaza
      @vadaza Рік тому

      They are on Instagram or telegram

    • @vadaza
      @vadaza Рік тому

      @Pham_smart11

  • @KaileeSmith-i9r
    @KaileeSmith-i9r Рік тому +1

    Love love love your videos!!

  • @adambingham7008
    @adambingham7008 Рік тому

    Reflux longer, run through vacuum flask w/glass filter. Bring to basic , separate in flask.

  • @jaimeortega4940
    @jaimeortega4940 Рік тому +3

    Low yield was probably a few things - purity of the starting chemicals, not completely or correctly reacting all the tin, and not having a fractional distillation apparatus. Great job Jesse!🔮🎱

  • @jasonpare-hm8rm
    @jasonpare-hm8rm 10 місяців тому

    What is that white pill shape thing (much bigger than a pill, just using that for shape)
    What is that white capsule in the beaker right before he added the foil

  • @Hallonyancat
    @Hallonyancat Рік тому +1

    Could have used a bong diffuser instead of a glass funnel

  • @freddyfender5397
    @freddyfender5397 Рік тому +1

    Make a video making it like we used to back in the day. Put a few ounces of Coleman fluid in the bottle 3 tbsp of ammonia 2 tablespoon of lye 15 240mg Sudafed pills and one AA lithium battery in that bottle. Close the lid fast as possible and shake it like crazy

  • @00gsgvfhryeyw
    @00gsgvfhryeyw Рік тому +3

    Do you think powder tin would be better?

  • @robertbledsoe6905
    @robertbledsoe6905 Рік тому +1

    That stuff is the meth build up on the walls of the glass when you started the last step of the procedure this was a very simple process thank you could you make meth from sassafrass oil as well curious is all

    • @dirtbag5408
      @dirtbag5408 11 місяців тому

      No. MDMA is possible with sass.

  • @ShahinKooshki
    @ShahinKooshki 9 місяців тому

    اقا یه سوال... این آزمایش
    ازمایش چی بود.
    جای میشناسی که ساخت شیشه اموزش بد با درصد بالا در بیار

  • @tpcqwe
    @tpcqwe 7 місяців тому +1

    I'm not in danger, I am the danger

  • @PoppaBadger
    @PoppaBadger 9 місяців тому

    Dude is absolutely brilliant, even if the content is questionable.lmao😂😅🙏🏼🙏🏼🙏🏼

  • @OmnicidaI
    @OmnicidaI Рік тому +1

    With this UA-cam tutorial I am ready to Break Bad like Walter White

  • @kingding9542
    @kingding9542 Рік тому +4

    Jessie
    We need to obey the law

  • @avilarkspur9266
    @avilarkspur9266 Рік тому +1

    Can you please tell me how to remove pseudoefredrine in cough syrup plz can anyone help me 😢

    • @terry-dd3dp
      @terry-dd3dp Рік тому

      I will refer you to online store I got mine stuff

    • @terry-dd3dp
      @terry-dd3dp Рік тому

      They are on Instagram and telegram

    • @terry-dd3dp
      @terry-dd3dp Рік тому

      @Pham_smart11

  • @uraninite8151
    @uraninite8151 Рік тому

    For the bubbling into the HCl try a fish tank glass and ceramic co2 diffuser. The fine bubbles produced with increase surface are. Im not sure if there would be enough pressure though. Also cover the top of the beaker…

    • @craigscolari361
      @craigscolari361 11 місяців тому

      Can anyone tell me were I could buy a cheap setup similar to this one?

  • @TheJonesMcCoy
    @TheJonesMcCoy Рік тому +3

    This is the kind of video needed by the world.

  • @jamesfry8983
    @jamesfry8983 Рік тому +1

    They have the recipe and instructions for this in the anarchist's cook book

  • @JuanaGethi-lj6ti
    @JuanaGethi-lj6ti Рік тому

    Dude your my new hero. Thanks

  • @user-yw9mw9hv8o
    @user-yw9mw9hv8o Рік тому

    How does the inverse funnel setup compare with a tube with a small opening, deeper into the HCl solution, in regards to rate of reaction. Thinking about the surface area of small bubbles and the time it takes them to rise, compared to how the gas phase sits on top of the liquid phase in the reverse funnel and there isn't much mixing except for the occasional 'fart'.

    • @chemdelic
      @chemdelic  Рік тому +1

      Yeah looking back at it, it wasn’t a good idea 😂

  • @chrisfowler1005
    @chrisfowler1005 Рік тому +1

    Iff anyone can make this properly or tell me how to do it with cold remedies n sudafed on the shake n bake method or I'm interested in buying chemicals to make it

    • @Raye-ml1hx
      @Raye-ml1hx Рік тому

      I will refer you to online store I got mine stuff

    • @Raye-ml1hx
      @Raye-ml1hx Рік тому

      @Pham_smart11

    • @Raye-ml1hx
      @Raye-ml1hx Рік тому

      They are on Instagram and telegram

    • @chrisfowler1005
      @chrisfowler1005 Рік тому +1

      Yeah man that would be good are they professional enough. For UK

    • @Raye-ml1hx
      @Raye-ml1hx Рік тому +1

      @@chrisfowler1005 yeah 👍

  • @MrSomethingElse
    @MrSomethingElse Рік тому +1

    dude... you are a legit boss

  • @QStyle-xt9iz
    @QStyle-xt9iz Місяць тому

    Chemdelic. Always good videos.
    Mate for legal reasons I was wondering if you can grow meth by the cold cook method/string dope As there are many rumours and even some papers about it out there.
    It would be a great video if you can throw it together
    Cheers
    Q