General Embryology - Detailed Animation On Second Week Of Development

Implantation of the blastocyst usually occurs 6-8 days after fertilization.
By day 8, the blastocyst has burrowed into the uterine wall, being completely embedded by day 9.
Day 8
The blastocyst is composed of two main components: the outer cell mass, the trophoblast; and the inner cell mass, the embryoblast.
As the trophoblast makes contact with the endometrium, it differentiates into two layers: an inner, cytotrophoblast; and an outer, syncytiotrophoblast.
The embryoblast differentiates into a bilaminar embryonic disc composed of two cell layers, the hypoblast, and the epiblast. Soon after the embryonic disc has formed, a cavity begins to appear between the epiblast and cytotrophoblast, known as the amniotic cavity.
Cells originating from the hypoblast begin to migrate, forming a thin membrane, which lines the inner surface of the cytotrophoblast. This is called the exocoelomic membrane. The exocoelomic membrane and cells of the hypoblast together form the walls of the primitive yolk sac.
Day 9
Once the blastocyst is completely embedded in the uterus wall, a plug called a fibrin coagulum forms in the gap created in the epithelium of the uterus by the blastocyst. At this time, the growth of the cytotrophoblast and syncytiotrophoblast is much faster than that of the bilaminar embryonic disc
Small holes called lacunae begin to form in the syncytiotrophoblast as it continues to expand.
Day 12
Capillaries in the endometrium surrounding the developing embryo dilate, forming maternal sinusoids. As the lacunae continue to expand, enzymes within the syncytiotrophoblast begin to erode the lining of the sinusoids and uterine glands. This allows anastomosis between the maternal sinusoids and lacunar networks to begin establishment of an uteroplacental circulation.
By day 12, the lacunae stop growing and fuse to form large interconnecting spaces, called lacunar networks.
A new population of cells appears between the inner surface of the cytotrophoblast and the outer surface of the primitive yolk sac, known as the extraembryonic mesoderm.
Large cavities begin to appear in the extraembryonic mesoderm. These gradually fuse to form one single cavity, called an extraembryonic coelom.
Day 13
Approximately 13 days after fertilization, a large portion of the exocoelomic cavity is pinched off, forming a smaller cavity, called the secondary yolk sac. A remnant also forms within the exocoelomic cavity, known as an exocoelomic cyst, which is eventually eliminated.
By the end of the second week of development, the chorionic cavity enlarges, and the bilaminar embryonic disc is joined to the trophoblast by a band of extraembryonic mesoderm called the connecting stalk.
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[@deborahcohen4045]

In the textbooks, there is so much stuff happening at the same time with the development of the embryo and of the formation of the future placenta, it can be confusing. So I love how you highlight what cells you are talking about and make all the other ones get a bit faded each time, so we know which specific layers you talk about. makes it so much clearer!

[@giorgosgranitsiotis]

Thanks thanks thanks I have exam in 3 hrs and it’s 5:30 am am studying all night procrastination FTW. (medical school btw...)

[@muhammadraza2766]

Did you pass then

[@rayzins6373]

@@muhammadraza2766 need to know this as well

[@ahmadyounes4102]

Same!

[@ogunladewilliam]

Same as you bro

[@jasmitkaurpuri]

I have an exam in 30 mins exact

[@mideadigun]

Almost 3 years in medical school and this is my first time understanding this. I genuinely don't know how to feel.
Thank you very much. I'm grateful.

[@saleemshahzad4215]

It's mind blowing for me that you can learn so much in just 4 minutes.I mean this is the first time that it makes sense to me and what I couldn't understand in 5 years of med school.
It's amazing how much output you get with a little effort. UA-cam is the way to go.👏👍

[@giftofthewild6665]

This seems very simplified, less detail than you would receive in med school surely?

[@royalroamer1]

@@giftofthewild6665yup, definitely

[@royalroamer1]

@@giftofthewild6665im in first year and its already way more than this lol 😂 (wish me luck)

[@yasmine9046]

The clearest explanations ever! I'm a french MS and I seem to struggle with this chapter as much as my fellow "international" MS. So much details and precise steps to learn. So thank you.

[@shh0hhdysf277]

I am a dental student and embryology is making me losing my mind

[@wajahatullahzakori2829]

Jazakullah. This topic is very tough but this video make it very very easy for me.

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+Wajahat ullah zakori agree

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what does it mean "wajahat ullah zakory"? 🤔

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رهَــفْ وجاهة الله زكوري

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@@None-fr1fi his name 🙄

[@arunasrirama152]

Thanks a lot!! It helped me to understand what my textbook couldn't do!!

[@Nora-dx9cy]

The second week is the most confusing one

[@docsafi7749]

lifesaver....
i cannot thank you enough for your well illustrated video lectures on Embryology...

[@deivibarci2093]

THE BEST VIDEOOO about the Development. It´s so complicated but you explained it so easily. Thanks a lot 🌟🌟

[@wathsalairoshiniwijesinghe1037]

this is the best!!!! This is highly recommended for everyone who has issues with understanding large unclear stuff regarding embryonic development .

[@hannahdavid3557]

I really liked the concept of the video. It is so much easier to understand such concepts through animations. Videos have made it so much easier for us. More videos of this sort should be uploaded. Keep up with the quality content. I hope you all the best. I am planning to opt for IVF process. I hope it works out for me.

[@davidstivenarboledaprado8731]

Thank u so much for this video, I`m would like to watch the third week. Amazing Job !

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amazing video!!! everything makes sense now! 😮😮😮❤❤❤

[@mohamedElyas97]

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[@mohamedElyas97]

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[@NurAfifah-uq5uv]

well, its the most clearly explanation that i've watch, thank you❤

[@254_Richie]

At first when I was reading on my own i couldn't understand anything thank you for deducing the information for us superb 👏👏

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OMG that was amazing please continue

[@nisarandil]

Hi I am a med student from Turkey and I am very thankful to you because of this video. Because I read my notes lots of time but I couldn’t understand. But now ,I can understand it. This video helped me even it upload 6 years ago. Thank you! (Sorry for my grammar mistakes)

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you literally saved me ... its 2020 now AND THANKS

[@northkay6391]

100% detailed and yet so short. Legend

[@vacaspen5038]

This is like mint this information and attitude and attitude. Of course there's space between my eyes of course there's space in your veins so that the blood can Roo but it's all one organism. I'm into lies. So yes the capillaries of the womb net to the embryo which already implanted to fuse as one.

[@haiderdhiaaformedicine112]

thank you, to be honest when i saw this videos, i really understood the embryonic development

[@ayahAhm]

you are the best I've been studying more than 8 hours and didn't get anything until I wached this video

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PLease keep posting videos!!! they are great!!! we are waiitng for the 4th week embryology video!!

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I love Kenya

[@nimmypokala]

THIS WAS SO GOOOOOOD thank you so so so much Medical Animations! this is exactly what we went through in class and i finally understand it better now with animations rather than words! thank you!!! god sent

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Glad it was helpful ❤️

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[@e.awdishu_MD]

Concise explanation of the embryonic cavities. Thx!

[@oy98]

this did for me what lectures could not do. thank you for posting!!!

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Thankyou so much the best video I have seen so far 👍🏼👍🏼👍🏼

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Thank you for the details description ☺️🙏

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[@callamontelongo7076]

Wish I had this video when I took this class back in May 2014. #lifeofafulltimestudent

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It would be amazing to have a PDF/storyboard of this video with detailed labels to study from :D

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Perfect explain❤

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Amazing 👏👏

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this is so good, the textbooks are not helping. this progress is so difficult that you need additional graphics to visualize whats going on...

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This was amzainggg

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