What Do Painkillers Actually Do???

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  • Опубліковано 15 січ 2025

КОМЕНТАРІ • 282

  • @BANANAMEMEZ
    @BANANAMEMEZ 2 місяці тому +924

    "Thing goes in, gets destroyed by burny burn, make brain be happy, boo boo goes bye bye. Goodbye everyone, thank you." - this.

  • @bakedchad
    @bakedchad 2 місяці тому +612

    You gotta love the "history of the entire world, i guess" reference

  • @junkice6930
    @junkice6930 2 місяці тому +170

    I do pharmaceutical research, and this is BY FAR the best video on NSAIDs I've ever seen. It explains exactly what happens, doesn't oversimplify, and explains things using English instead of stupid names. 10/10

    • @simpleneeds2582
      @simpleneeds2582 2 місяці тому

      @@junkice6930 a painkiller is a big word blocker

    • @y_e_s_L
      @y_e_s_L Місяць тому +3

      What is nsaids

    • @davidu9904
      @davidu9904 9 днів тому

      @@y_e_s_Lnonsteroidal anti-inflammatory drugs

    • @MykytaSpivak-ne3cw
      @MykytaSpivak-ne3cw 7 днів тому

      ​@@y_e_s_L non-steroidal anti-inflammatory drugs

    • @123brunekk
      @123brunekk 7 днів тому

      @@y_e_s_L short for Non-Steroid Anti-Inflammatory Drugs

  • @Yotomataspatatas
    @Yotomataspatatas 2 місяці тому +343

    1:00 "What is pain" *Vsauce Music intensifies*

    • @this.science
      @this.science  2 місяці тому +104

      i was thinking about putting that in, but was scared of copyright lol

    • @kuldeep130
      @kuldeep130 2 місяці тому +20

      @@this.science you should've.. I was expecting vsauce face to pop out of nowhere

    • @redyau_
      @redyau_ 2 місяці тому +11

      ​@@this.scienceThe first two chords just for the meme can't hurt! :P

    • @ILoveMath_Cats_Coding
      @ILoveMath_Cats_Coding Місяць тому

      @@this.scienceeven just the first “blum!”

  • @TreFR14
    @TreFR14 2 місяці тому +248

    I love how bro just uploads the most random explaining video ever at the most random time of the day lol

    • @solitivity
      @solitivity 2 місяці тому +8

      Oh, haha. Right. Like bro just is randomly putting on pants in the morning and randomly brushing his teeth to start his random day. Lol. Everything's just so... random. Haha.

    • @fun_g
      @fun_g 2 місяці тому +6

      bro bros about too many bros

    • @hish33p32
      @hish33p32 2 місяці тому +1

      Kinda like Zack'D Films

  • @Zachrdoodle
    @Zachrdoodle 2 місяці тому +91

    Now when I take painkillers I will imagine them as little monkey aces, going to pop the bad bloons (pain chemicals). Thank you for forever altering my perception of pharmaceuticals.

  • @Ashws_
    @Ashws_ 2 місяці тому +38

    this video went from my stomach to my brain and somehow made me understand painkillers

    • @xxGreenRoblox
      @xxGreenRoblox 2 місяці тому

      how did you eat words and video

  • @chandanasri7404
    @chandanasri7404 2 місяці тому +19

    5:20 what’s a purge? Guess I’ll have it cuz I don’t want any more problems in life, which a zombie apocalypse does do.

    • @manceenee0071
      @manceenee0071 2 місяці тому

      i think it refers to the movie the purge, basically for a day any crime would be legal so some people that hate you might come to kill you, zombies are better, if its for a day its just an easy surviving challenge, you dont have classic apocalypse problems like food ending cuz if you wait for tomorrow its all good again, it would be fun imo

    • @Henryisdjfunkyho
      @Henryisdjfunkyho Місяць тому

      I almost forgot sone thing that will help the pause gaming you can use the period and comma to move only one frame on p

  • @adityasasank
    @adityasasank 2 місяці тому +51

    Day long zombie apocalypse 💀☠️

    • @shklee
      @shklee 2 місяці тому +4

      i mean it sounds like fun in my head

    • @miguel.morillo
      @miguel.morillo 2 місяці тому +2

      I still would prefer it

  • @Ollieball44
    @Ollieball44 2 місяці тому +55

    1:37 history of the the entire world I guess reference???????

  • @israeljohnson4446
    @israeljohnson4446 2 місяці тому +7

    I really love the way this dude explains things. ❤

  • @kindagamer525
    @kindagamer525 2 місяці тому +39

    Isn't it obvious? It kills the pain.

  • @mattm1388
    @mattm1388 Місяць тому +1

    day long zombie apocalypse, the zombies are easier to defeat than the purge

  • @shuttleboi6482
    @shuttleboi6482 2 місяці тому +5

    this channel is so good that i want to watch more vids but then there’s no more vids that i haven’t watched

    • @this.science
      @this.science  2 місяці тому +4

      thank you! out of curiosity, which one's your favorite?

    • @tokito2216
      @tokito2216 2 місяці тому +1

      fr tho I subscribed to his channel when I was in the middle of his first video that I saw and watched the rest in 2 days

    • @tokito2216
      @tokito2216 2 місяці тому +1

      @@this.science I think it might be the sound related one but to be honest all of them :D

    • @manceenee0071
      @manceenee0071 2 місяці тому

      @@this.science "this."

  • @BlueScreaming
    @BlueScreaming 2 місяці тому +34

    I eat ten of these a day for fun

  • @AnshLuvsCash
    @AnshLuvsCash 2 місяці тому +6

    2 videos in under 3 weeks? My prayers have been answered.

  • @flamshiz
    @flamshiz Місяць тому +1

    it doesn't beg the question. it raises the question

  • @P_L_A_Y
    @P_L_A_Y 2 місяці тому

    I really appreciate that you make these very short and very informative educational videos, not like the other channels that make 10 to 30 minute videos just to waste your time and get that juicy ad money

  • @RaniRani-zt2tr
    @RaniRani-zt2tr 2 місяці тому +1

    Very cool analogy to explain the neurotransmitters and the receptors😂

  • @MichaelShaw08
    @MichaelShaw08 Місяць тому +1

    Zombie apocalypse if there’s no way I could be infected

  • @AngelMartinez-mg1ok
    @AngelMartinez-mg1ok 2 місяці тому +1

    This is actually the calmest video from this. i've ever seen

  • @sjnt
    @sjnt 2 місяці тому

    Watching this right after taking my pill. I'm just impatient to feel better, so I try to obtain a sense of control on the situation for it to seem to go faster...
    The pain is REALLY bad.

  • @J0ZZ_20
    @J0ZZ_20 2 місяці тому +4

    I love this channel

  • @youfacejarraxus3392
    @youfacejarraxus3392 4 дні тому

    This man does a better job teaching me pharmacology than college

  • @indikativ8611
    @indikativ8611 2 місяці тому +1

    nah the btd6 ace
    😭😭😭😭😭

  • @doropro1756
    @doropro1756 2 місяці тому +1

    The Bloons reference 😂

  • @TheTeluguBengalurean
    @TheTeluguBengalurean 2 місяці тому +6

    1:50 small correction, I don't believe it is electricity that actually gets transmitted through the nerve cells, but rather an impulse is created by the inward movement of sodium ions, which in turn produces an impulse in the neighboring nerve cells and so on. I only have a basic idea of the nervous system, I might be wrong, but as per my knowledge, it is not electricity that travels through nerve, feel free to correct me.
    Other than that, great video!

    • @limitless9332
      @limitless9332 2 місяці тому

      i think u are mostly correct, it is more of a wave of depolarisation (caused by movement of sodium ions) that is transmitted via the neurones

    • @ZeRasseru
      @ZeRasseru 2 місяці тому

      Which, I think, is basically how an electric field functions. And electric fields and electric current are, if I'm not misremembering my physics classes, interchangeable/the same thing.
      Plus, if we want to make it simple, we should avoid those type of complications. Imagine adding a explanation to depolarisation in that video. That's a solid +2-3 min that would be needed. Possibly ruining the flow of the video

    • @TheTeluguBengalurean
      @TheTeluguBengalurean 2 місяці тому

      @@ZeRasseru Yea, you are right, adding in that explanation would increase the video length, its just that during my biology exams and classes, the difference between a neural impulse and electricity was a pretty common question, so I just have a habit of differentiating it wherever I see it, but yea u are right, they are more or less the same, and it would take up unnecessary time

  • @leol.370
    @leol.370 2 місяці тому

    Dude how I love your videos fr

  • @melodious_moon
    @melodious_moon 2 місяці тому +1

    Pharmacy student here :3
    I know how NSAIDs work because of studying boring textbook words, but I always have trouble remembering certain concepts because the boring textbook words are… boring.
    Thank you for the great video!!! I love your channel. It makes me feel like making my own videos like this someday about medicine. Maybe when I graduate :D

    • @evilsillyhill
      @evilsillyhill 2 місяці тому

      pharmacy student can you tell me which prescription drugs i can make meth with

  • @carlsong6438
    @carlsong6438 2 місяці тому

    1:37 that bill wurtz reference was absolute gold

  • @AlanAces52
    @AlanAces52 2 місяці тому

    Bro literally just said its all a mental game. I love This

  • @TheSfelex
    @TheSfelex 2 місяці тому

    That was really really really nice to learn and understand, thank you for the very well done explanation :D

  • @KilobitePandaMusic
    @KilobitePandaMusic 2 місяці тому +1

    they kill the pain, duh.

  • @foreducation408
    @foreducation408 2 дні тому

    I stupidity thought this was gonna be as easy as the bluetooth video, oh boy i was so wrong, it's good thing i am a software engineer rather then a doctor, still awesome video man.

  • @user_breathless
    @user_breathless 2 місяці тому

    Love these videos. As soon as I saw the getting girls science video I was hooked on this channel

  • @its_jo5hu472
    @its_jo5hu472 2 місяці тому +1

    This guy finally upload a new video!!!!

  • @jabeztadesse
    @jabeztadesse 2 місяці тому

    OMG, the way they work feels like a violation.

  • @Snako
    @Snako 2 місяці тому

    As a med student, this was beyond phenomenal, i never really grasped my brain around these guys before, Thanks a trillon!! 😂

  • @Touplopl
    @Touplopl 2 місяці тому

    A day long zombie apocalypse would be more fun ngl

  • @yes6362
    @yes6362 2 місяці тому +1

    BABE WAKE UP, This. UPLOADED A NEW VIDEO AFTER 2 WEEKS 🔥🔥🔥🔥🔥🔥‼‼‼‼🗣🗣🗣🗣lowkey a longer This. video on a Friday night would've gone HARDDD but i cannot complain at all 🔥🔥🔥🔥‼‼⁉⁉

  • @vishwajeetdahale882
    @vishwajeetdahale882 2 місяці тому

    This guy from This. is answering our 3 am questions. Thankyou This.

  • @erenal456
    @erenal456 2 місяці тому

    I like how you explain things, i really enjoyed watching your videoo

  • @lampgod0
    @lampgod0 2 місяці тому

    The zombie apocalypse sounds better because I feel like people can handle it better than if they just where purged by real, lucid, humans.

  • @juliusfoster3647
    @juliusfoster3647 6 днів тому

    bro i wish you were my science teacher you make to learn this actually fun

  • @Grant0942
    @Grant0942 2 місяці тому

    probably the day long zombie apocalypse, because then your fighting zombies and not other people. Also I just really like apocalypse movies like Love and Monsters where you can kindve be more chill i guess, i dont think you could get that from a day long purge

  • @Santjaho
    @Santjaho 2 місяці тому +1

    I'd like some apocalypse

  • @nabri-nfg3262
    @nabri-nfg3262 2 місяці тому

    Wow you answered a question I’ve always been curious about, but never curious enough to actually research

  • @Masea_1
    @Masea_1 2 місяці тому +3

    A zombie apocalypse of course

  • @ethervescent6591
    @ethervescent6591 2 місяці тому

    1:37 elite reference

  • @rabih7969
    @rabih7969 12 днів тому

    Good job, very nice channel! Looking forward to you uploading more videos!

  • @EverythingTechTime
    @EverythingTechTime 2 місяці тому +3

    0:52 Its been so every you don't even need a where

    • @gekoneq347
      @gekoneq347 2 місяці тому +1

      Bro I read this comment before 0:52 and I've got an aneurysm

    • @swirlsynx
      @swirlsynx Місяць тому

      you don't even need a when, thats how E V E R Y it gets!

  • @parkaller7959
    @parkaller7959 2 місяці тому

    Lots of Bill Wurtz inspiration in this one, I like it

  • @CherryBomb-i1t
    @CherryBomb-i1t 2 місяці тому

    thank you actually that was extremally well explained

  • @_SliK_
    @_SliK_ 2 місяці тому +2

    They help me sleep…

  • @CJ0611
    @CJ0611 2 місяці тому +1

    WE ARE SO BACK

  • @gabqt.mp3
    @gabqt.mp3 2 місяці тому

    they kill the pain

  • @pigeon_hole
    @pigeon_hole 2 місяці тому

    As a pharmacist, I love this

  • @protectev
    @protectev 2 місяці тому

    a day long zombie apocalypse would be better because zombies are easier to take care of

  • @NavinC.S.
    @NavinC.S. 2 місяці тому

    Finally the answer to this mystery

  • @SISINGA
    @SISINGA 16 днів тому +1

    01:38 mahajapit moment...

  • @simpleneeds2582
    @simpleneeds2582 2 місяці тому

    it doesn't reduce pain, it blocks the signals that indicate pain

  • @DeltaGaiya
    @DeltaGaiya 2 місяці тому

    Day long apocalypse, use it as an excuse to not go out

  • @arpan2030
    @arpan2030 2 місяці тому

    a day long zombie apocalypse

  • @fluffffycat
    @fluffffycat 2 місяці тому

    1:38 I love @billwurtz references

  • @Biddddy
    @Biddddy 2 місяці тому +1

    its almost like hes still here.. 🕊

  • @emiliorojo2625
    @emiliorojo2625 2 місяці тому

    Zombie apocalypse, definitely not dealing with actual people doing actual crime

  • @mehdibmc9508
    @mehdibmc9508 2 місяці тому

    day long zombie apocalypse for sure

  • @Ashws_
    @Ashws_ 2 місяці тому

    The stomach acid looking at my Advil: 'this. this is bad news'

  • @nathan1507
    @nathan1507 Місяць тому

    Majapahit reference?? We beating the Mongols with this one.

  • @MyReviews_karkan
    @MyReviews_karkan 2 місяці тому

    That check out machine gets me every time 😂
    Anyway, tell me we don't live in a simulation. This is all witch craft.

  • @CRTR2112
    @CRTR2112 2 місяці тому

    A day long zombie apocalypse, humans are scary

  • @cheesy7805
    @cheesy7805 2 місяці тому

    So that’s why the 4 Advils that I took did nothing to stop my excruciating pain, neat!

  • @cooper.quinlivan
    @cooper.quinlivan 2 місяці тому

    Can’t believe I’ve never given this a second thought

  • @bobbiejoringulet5040
    @bobbiejoringulet5040 2 місяці тому

    Dude named pain:

  • @deeeeeeeeeeeeeeeeeeeeeeeee6925
    @deeeeeeeeeeeeeeeeeeeeeeeee6925 2 місяці тому +2

    Great video I loved every second of it (yes I watched the whole thing what are you talking about)

  • @levzarechny8941
    @levzarechny8941 2 місяці тому

    Purge seems to me more survivable, so i choose zombie apocalypse

  • @makkroww6097
    @makkroww6097 2 місяці тому

    1:36 this might be perhaps a bill wurtz reference

  • @hellmine
    @hellmine 2 місяці тому

    a day long zombie apocalipse

  • @ScreenAI
    @ScreenAI 2 місяці тому

    I wasn't expecting This.

  • @fumikato
    @fumikato 2 місяці тому

    man, your explanation is so fun 😂.

  • @wahyu4853
    @wahyu4853 Місяць тому

    Ok, now how anti depressant work? Like this thing literally make day brighter and silent my brain

  • @ones9638
    @ones9638 2 місяці тому

    thanks for reminding me to take ibuprofen!
    also nice bill wurtz reference

  • @plill0_wmcfethers708
    @plill0_wmcfethers708 2 місяці тому

    day long zombie apocalypse. it'll be like its 2019 again.

  • @AnonymousAccount514
    @AnonymousAccount514 2 місяці тому

    wow...its pretty amazing that we understood this back in the 1800s

  • @ChelseaStand0
    @ChelseaStand0 2 місяці тому

    Kill the pain of waiting for you to upload

  • @kryger4840
    @kryger4840 2 місяці тому

    good video. much appreciated

  • @pradix5176
    @pradix5176 2 місяці тому

    You are really good at making the thumbnails always makes me click the video

  • @jashn8962
    @jashn8962 2 місяці тому +1

    I knew how painkillers work still I learned somethings new

  • @SmugHomura
    @SmugHomura 2 місяці тому

    ma-ja-pa-hit ✅
    Great video!

  • @BennettWelch-giant.
    @BennettWelch-giant. 2 місяці тому

    Day long zombie apocalypse obv

  • @byford-fe8lq
    @byford-fe8lq 2 місяці тому

    Not sure for author’s mysterious speed of upload 😊

  • @PoleBrotherhood
    @PoleBrotherhood 2 місяці тому +1

    Hey can you make a video on psychedelic's (Lsd, shrooms, DMT) cause their benefits/mechanism of action explained would be very interesting

  • @jamesmck896
    @jamesmck896 2 місяці тому

    Love your videos ❤️❤️😍

  • @TimothyTCB
    @TimothyTCB 2 місяці тому

    loved the bill wurtz reference

  • @willowkeeper7663
    @willowkeeper7663 2 місяці тому

    Going to have to go with the zombie apocalypse. it would be fun to experiment on them

  • @notarealpillow6273
    @notarealpillow6273 2 місяці тому +2

    What about fentanyl

  • @tomiey_1520
    @tomiey_1520 2 місяці тому

    You make great content.Keep it up. 🥞

  • @Rns-Dayavi
    @Rns-Dayavi 2 місяці тому

    What if you take both!

  • @gaelangelmorales6829
    @gaelangelmorales6829 2 місяці тому

    A NEW ONE!

  • @evidencenugget
    @evidencenugget 2 місяці тому

    Me watching this after taking Advil for Headache: 👁👄👁