I love Ron Davis! He does these interviews to ensure patients know scientists are working hard on their behalf. It really does make a big difference to know these scientists support people with ME/CFS
I’m so grateful for Professor Ron Davis and all those working for ME/sufferers. I don’t understand a lot of what has been mentioned but after 40 years, like so many others, I’m so desperate for the research, better treatment and a cure or even 40% of my life back. I wish a lot more money could be found! Thanks Professor Davis 🥰👍🏻
Being one of these patients I can absolutely second that impession. It is more than wonderful hearing about this progress! Thank you efer so much for everyone involved!
Great to hear that Ron Davis and his lab remain committed to research into ME/CFS. I hope they are able to gather samples for the neutrophil study reasonably quickly. Props to Danielle for conducting these interviews, all of which have been informative - she asks good follow-up questions and has a warm demeanor. She’s an asset to OMF.
Thank you so much both for your innovative work and for sharing it with us here. Reminds me of Jarred Younger’s efforts to look at new details in brains.
Interestingly, I was told about a decade ago that my neutrophils were 'sluggish'. I was seeing a naturopath who examined my blood under the microscope every session. We managed to improve some issues that were detectable in the blood, yet we weren't able to improve this function of the neutrophils. I'm really interested to see what can be found out about this dysfunction. Thank you Dr Ron Davis & team for researching this.
Thank you for this uplifting video!!! Please, though, you absolutely need to give last names to Vanessa and the mathematician. Please list them under Persons mentioned if you can. It's so important to give real credit where it is due, especially to females. Especially in Science.
I trust Dr Davis completely when he says they're working really hard, but I still have like 20 questions! The main of which is: so what happened to testing all FDA-approved drugs in some assay with a robot they needed to fix? And did they prove itaconite shunt existence? Much unknown!
Dr Davis looking a bit tired. I hope he gets enough rest in between all his research, conferences, interviews, personal life, etc. Thank you for all your hard work, it is appreciated :)
Thank you so much to everyone at the OMF and for this video. I'm curious when this video was filmed? There is still a pandemic and covid is still a big risk especially to ME patients but it's still odd to hear Ron refer to current times in this way in 2024. If it's recent I think it's great they are still listening to patients and finding innovative ways to keep them safe! Deeply appreciate the work being done and shared with us.
Sorry I’m still not clear on why they decided to look at neutrophils. Just because no one has? Is it a case of no stone unturned or is there other evidence pointing towards them? I do appreciate the updates.
Pathological NETs seem to contribute to immunothrombosis in long COVID too. For example this 2023 study: NETosis induction reflects COVID-19 severity and long COVID: insights from a 2-center patient cohort study in Israel Conclusions: "Increased NETosis induction can be detected in patients with long COVID. NETosis induction appears to be a more sensitive NET measurement than MPO-DNA levels in COVID-19, differentiating between disease severity and patients with long COVID. Ongoing NETosis induction capability in long COVID may provide insights into pathogenesis and serve as a surrogate marker for persistent pathology. This study emphasizes the need to explore neutrophil-targeted therapies in acute and chronic COVID-19. "
I love Ron Davis! He does these interviews to ensure patients know scientists are working hard on their behalf. It really does make a big difference to know these scientists support people with ME/CFS
I’m so grateful for Professor Ron Davis and all those working for ME/sufferers. I don’t understand a lot of what has been mentioned but after 40 years, like so many others, I’m so desperate for the research, better treatment and a cure or even 40% of my life back. I wish a lot more money could be found!
Thanks Professor Davis 🥰👍🏻
Being one of these patients I can absolutely second that impession. It is more than wonderful hearing about this progress! Thank you efer so much for everyone involved!
I love that such cutting edge scientific work is being done, let alone in the name of ME/CFS research.
Great to hear that Ron Davis and his lab remain committed to research into ME/CFS. I hope they are able to gather samples for the neutrophil study reasonably quickly. Props to Danielle for conducting these interviews, all of which have been informative - she asks good follow-up questions and has a warm demeanor. She’s an asset to OMF.
Thank you for all your hard work and sharing it with us 🙏
thank you Dr. Davis!!!!!!!!!
Could be related to the circulation "dehydration resulted in immunosuppression, including decreased neutrophil function."
Love these updates! He is so good at explaining these complex things. Thank you!
Thank you so much both for your innovative work and for sharing it with us here. Reminds me of Jarred Younger’s efforts to look at new details in brains.
Interestingly, I was told about a decade ago that my neutrophils were 'sluggish'. I was seeing a naturopath who examined my blood under the microscope every session. We managed to improve some issues that were detectable in the blood, yet we weren't able to improve this function of the neutrophils. I'm really interested to see what can be found out about this dysfunction. Thank you Dr Ron Davis & team for researching this.
That’s very exciting!
Thank you for this uplifting video!!! Please, though, you absolutely need to give last names to Vanessa and the mathematician. Please list them under Persons mentioned if you can. It's so important to give real credit where it is due, especially to females. Especially in Science.
I trust Dr Davis completely when he says they're working really hard, but I still have like 20 questions! The main of which is: so what happened to testing all FDA-approved drugs in some assay with a robot they needed to fix? And did they prove itaconite shunt existence? Much unknown!
Dr Davis looking a bit tired. I hope he gets enough rest in between all his research, conferences, interviews, personal life, etc. Thank you for all your hard work, it is appreciated :)
Thank you so much to everyone at the OMF and for this video. I'm curious when this video was filmed? There is still a pandemic and covid is still a big risk especially to ME patients but it's still odd to hear Ron refer to current times in this way in 2024. If it's recent I think it's great they are still listening to patients and finding innovative ways to keep them safe! Deeply appreciate the work being done and shared with us.
Yeah I too was like: "What pandemic?"... 🤔
Thank you.
Could someone explain how neutrophils relate to mast cells? Are they not both types of white blood cells? TIA
Sorry I’m still not clear on why they decided to look at neutrophils. Just because no one has? Is it a case of no stone unturned or is there other evidence pointing towards them? I do appreciate the updates.
Pathological NETs seem to contribute to immunothrombosis in long COVID too. For example this 2023 study:
NETosis induction reflects COVID-19 severity and long COVID: insights from a 2-center patient cohort study in Israel
Conclusions:
"Increased NETosis induction can be detected in patients with long COVID. NETosis induction appears to be a more sensitive NET measurement than MPO-DNA levels in COVID-19, differentiating between disease severity and patients with long COVID. Ongoing NETosis induction capability in long COVID may provide insights into pathogenesis and serve as a surrogate marker for persistent pathology. This study emphasizes the need to explore neutrophil-targeted therapies in acute and chronic COVID-19. "
ME for 34 years, my neutrophils and natural killer cells are almost always low in blood tests. Wondering if this is true for other people with ME?