Could CRISPR democratise diagnostics? | Janice Chen | TEDxCERN

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  • Опубліковано 10 лис 2024
  • An early detection of diseases is often key to patients’ survival. And if this could be done in a fast, cheap and very accurate way, perhaps using our phone, then the future of medicine could be really revolutionised. In her young career, Janice Chen, a recent PhD graduate in Molecular and Cell Biology from the University of California, Berkeley, has co-created DETECTR, a programmable DNA detection technology based on the CRISPR gene editing tool. The new diagnostic tools developed by Chen and her colleagues could help us identify bacterial and viral infections, detect cancerous mutations as they happen, and recognise new outbreaks before they spread out. But they also trigger some ethical questions regarding data ownership and diagnostic counseling. Should we be able to diagnose diseases without physician oversight? We need to make decisions now as the technology is already available. Janice Chen did her graduate studies under CRISPR pioneer Jennifer Doudna. After her PhD at UCL, she went on to become the co-founder and Chief Research Officer at Mammoth Biosciences, a biotechnology company harnessing the CRISPR technology to create a rapid and
    affordable disease detection. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

КОМЕНТАРІ • 20

  • @lisaward6698
    @lisaward6698 2 роки тому +5

    AMAZING! Janice explained this tool in a way regular people, like me, can understand!

  • @tannerbellisle4184
    @tannerbellisle4184 5 років тому +13

    WOW! You're amazing, what a talented family!

  • @lainjijustin979
    @lainjijustin979 5 років тому +17

    Came here because of Nathan Chen

  • @abbieprice3430
    @abbieprice3430 2 роки тому +10

    That’s one of Nathan Chen’s sisters!

    • @629Justme
      @629Justme 2 роки тому +1

      Yes. Talk about an overachieving family. She's in the startup mode of an expected 100 billion dollar company. 100 Billion. Im impressed.

  • @TrevorClydesdale
    @TrevorClydesdale 8 місяців тому

    As a kid I played chess with Janice! It’s amazing to see how far she has come.

  • @Vandylizer
    @Vandylizer 5 років тому +5

    Janice Chen, if you (or anyone "in the know") are reading this: I love this diagnostic tool! Is there a way we can publicly invest in the success of this tech? I'm invested in Ms. Doudna's Crisper Therapeutics and Ms. Charpentier's Intellia (and EDITAS, which I assume is overseen by the guy who did preliminary research on CRISPR prior to JD and EC). Is Mammoth Biosciences funded by a publicly traded company we can invest in? Feel free to privately message me here on UA-cam or respond to this comment. Keep up your amazing work! Super excited about a future full of CRISPR tech :D

  • @frommbmars7157
    @frommbmars7157 5 років тому +6

    Now a TED talk about the dangers please :)

    • @opritchard8611
      @opritchard8611 5 років тому

      From mb Mars apply yourself. You dont need a ted talk to explain things if you are educated in the biomedical field. Theres no point someone explaining the risks if you cant appreciate all of the potential. We can control the virus mechanisms to apply crispr, it is of course subject to damage just like DNA damage that leads to non-functional cells etc. As such crispr is a while off of being implemented due to issues of un-wanted crispr outcomes happening - dont concern yourself with these “risks” because they are understood in the field and wont be able hit legal treatment market without them being solved. The only risk outside this is its potential application in the future for non-condition application like eye colour - thats something that will develop laws around and goverments will decide how far that rabbit hole goes.

    • @franciscorompana2985
      @franciscorompana2985 5 років тому +2

      The perspn implementing and studying a subject should be able to speak about it's side effects. They are just public relations and communications professionals looking for investment.

    • @AdamIdoine
      @AdamIdoine 4 роки тому +4

      I think you're conflating using CRISPR as a genome editing tool with using CRISPR as an in vitro diagnostic tool. This video is about using it to diagnose diseases or infections, not to edit DNA.

    • @rjakelian
      @rjakelian 2 роки тому

      DuckDuck Go it...

  • @belieber888
    @belieber888 4 роки тому +2

    A double-edged sword

  • @frommbmars7157
    @frommbmars7157 5 років тому +4

    If you use it the right way … awesome. But what if …. ???!!???

  • @digitall6166
    @digitall6166 4 роки тому

    Another example of politics over science ... politics is of the level of cheap marketeers and the science community can't break through ... no Covid test yet ...