Maximizing IVF Success Rates with Genetic Testing: PGT, PGD, PGS Explained

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  • Опубліковано 19 жов 2024

КОМЕНТАРІ • 39

  • @pratipalsingh990
    @pratipalsingh990 Рік тому +2

    Salute sir, very nicely explained the intricacies of pgt-a

  • @user-vq3qr4uu7o
    @user-vq3qr4uu7o Рік тому

    Great video. If one of the parents has a genetic heart condition where there is 50% chance it could be passed along to the baby, would you recommend the testing even though there is some risk to the embryo.

    • @ivfexpert
      @ivfexpert  Рік тому

      Yes, but only if you have a specific genetic diagnosis for which probes for testing are available

  • @manoramajagtap6561
    @manoramajagtap6561 Рік тому

    Hello Sir, Having 1st mild Autistic child due to epilepsy, is it useful to do PGD test while doing IVF process ?? Specially when had 1st failed IVF cycle....please advise is tbere any other way to work on ...thanks

    • @ivfexpert
      @ivfexpert  Рік тому

      No - PGD will not help, so please don't waste your money
      I need more information to be able to provide you with intelligent advise.
      Can you send me more details about your IVF cycle ?
      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      PLEASE SEND ME PHOTOS OF YOUR EMBRYOS
      Can you please send me the printed treatment summary from your IVF clinic ?
      Please email this to me at drmalpani@drmalpani.com
      We look forward to helping you to have another baby !

  • @sambitmishra8822
    @sambitmishra8822 Рік тому

    Namaste sir .I would like to ask u that should i go for NICS testing of embryo in icsi with 2 icsi cycle failures .does it increase my chances if i will go for NICS ..AND my 2nd question is should i go for ERA Test or not .

    • @ivfexpert
      @ivfexpert  Рік тому

      PGS reduces pregnancy rates in my opinion. Read more at blog.drmalpani.com/2015/05/how-pgs-overpromises-and-underperforms.html
      The ERA ( Endometrial Receptivity Assay ) tests are a waste of time and money.
      Read more at www.drmalpani.com/knowledge-center/articles/why-the-new-expensive-endometrial-receptivity-tests-are-useless
      I need more information to be able to provide you with intelligent advise.
      Can you send me more details about your failed IVF / ICSI cycles ?
      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      PLEASE SEND ME PHOTOS OF YOUR EMBRYOS
      Can you please send me the printed treatment summary from your IVF clinic ?
      Please email this to me at drmalpani@drmalpani.com
      We look forward to helping you to have a baby !

  • @ajaysel08
    @ajaysel08 9 місяців тому

    Sir in our first pregnancy, baby is diagnosed with Jacob Syndrome (47XYY) and minor thalassemia. How should we proceed. Its about 19 week of pregnancy. Should we abort or continue...??
    And if abort what should be done in future to get healthy baby.

    • @ivfexpert
      @ivfexpert  9 місяців тому

      I am an IVF specialist and this is not my area of expertise, sorry

  • @RitikaBanal
    @RitikaBanal 3 місяці тому

    My husband is identified to be the carrier of balanced translocation involving
    chromosomes 11 & 22.
    Doctor suggested us to do ivf with genetic testing. Is it really necessary??
    In past 5.5 year i hv also gone through 2 miscarriages ,means 2 DNC done and multiple painful test as well

    • @ivfexpert
      @ivfexpert  3 місяці тому

      PGT will not help, sorry
      Was genetic testing done on your products of conception when you miscarried ?

  • @AnaghaKP-v6i
    @AnaghaKP-v6i 2 місяці тому

    Hi doctor both of our egg and sperm are normal but even after 4 ivf we have not got successs. We usually get very low embryos count even if large numbers of egg obtained . Can this be a possibility of genetic issue with embryo ? Or receptive issue

    • @ivfexpert
      @ivfexpert  2 місяці тому

      This is often because of a bad IVF clinic
      I need more information to be able to provide you with intelligent advise.
      Can you send me more details about your IVF cycles ? What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at www.drmalpani.com/knowledge-center/ivf/embryos
      Can you please send me the printed treatment summary from your IVF clinic ?
      You can email me for a free second opinion . My email is drmalpani@drmalpani.com. Please mark a copy to frontdesk@drmalpani.com also

  • @miltonjesurajan1950
    @miltonjesurajan1950 День тому

    Hi sir, my wife had 6 abortions but she is internally good ( leproscopy& hitroscopy & d&c report). karyotype result my side 22ps+ and wife side ok and genetic counseling its a normal varient that will any repeated abortions told.. Need your advise sir

    • @ivfexpert
      @ivfexpert  2 години тому

      Yes, this can be very frustrating !
      You can email me for a free second opinion . My email is drmalpani@drmalpani.com. Please mark a copy to frontdesk@drmalpani.com also

  • @aashutoshdabhade4325
    @aashutoshdabhade4325 Рік тому

    Sir my spouse has familial polyposis disease which is life threatening. Our health is completely good to have a normal pregnancy. But we want to prevent the disease to get transferred in next generation. And we have decided to go with IVF and PGD. Will it be effective in our case. Or there will be still chances of getting it transferred to child?

    • @ivfexpert
      @ivfexpert  Рік тому

      As long as you have the genetic probes to test for this, your baby will not have this disease

  • @sahilgupta1254
    @sahilgupta1254 3 місяці тому +1

    Hello sir.....We have gone first IVF cycle and my wife got pregnant with 2 babies but first some heart beat was there and after 2-3 months due to lack of heart beat ,we have to abort .Now before second cycle we went for Karyotyping and found that my wife have chances of 50-60% chance of miscarriage or abnormalities.Now doctor suggested PGD. pls suggest something.

    • @ivfexpert
      @ivfexpert  3 місяці тому +1

      I need more information to be able to provide you with intelligent advise.
      Can you please share the karyotyping report !
      PGS reduces pregnancy rates. www.drmalpani.com/knowledge-center/articles/pgs-pgd-pgt-testing-can-reduce-pregnancy-rates
      You can email me for a free second opinion . My email is drmalpani@drmalpani.com. Please mark a copy to frontdesk@drmalpani.com also

    • @sahilgupta1254
      @sahilgupta1254 3 місяці тому

      @@ivfexpert yes sir will send you reports on email

    • @AlfiyaShaikh-ve9sp
      @AlfiyaShaikh-ve9sp Місяць тому

      Aapne karwaya plz reply

  • @rpa6646
    @rpa6646 9 місяців тому

    Hi Doctor . Thanks for this wonderful explanation. My doctor suggested PGTA testing for my three embryos as I was in the higher Side of age .Age 40.I had 12 eggs out of which 8 were fertilized.3 went to blastocyst stage with grades 4AA 3AA 2AA .Once PGTA test result came they told my embryos were abnormal and discarded all of them.Somewhere still I feel this test result is not correct and I lost my three precious good blastocyst embryos. I am very depressed

    • @ivfexpert
      @ivfexpert  9 місяців тому

      Yes, this is tragic. PGS reduces pregnancy rates in my opinion. Read more at blog.drmalpani.com/2015/05/how-pgs-overpromises-and-underperforms.html

    • @rpa6646
      @rpa6646 9 місяців тому

      @@ivfexpert Thanks Doctor. I am in Bangalore . How should I contact you for my second IVF. Both me and my husband are healthy and don’t have any health issues as such . We want a baby of our own gametes.

  • @rajulgupta5026
    @rajulgupta5026 22 дні тому

    Sir i have Gilbert syndrome...can pgd ivf will help us to prevent this into our children..i am so worried plz help me

    • @ivfexpert
      @ivfexpert  22 дні тому

      Gilbert syndrome has no serious medical consequences, which is why it's not a good idea to do PGT for this

    • @rajulgupta5026
      @rajulgupta5026 22 дні тому

      @@ivfexpert if I want to do..then it is possible to do for it

  • @lipsasahu5771
    @lipsasahu5771 Рік тому

    Sir my ivf 1 st cycle is failed.. They said I have 3 grade 1 quality embryo and at the time of embryo transfer my et is 10.3 ecogenic... Can you please sir guide me

    • @lipsasahu5771
      @lipsasahu5771 Рік тому

      They don't provide any photos of embryo.. Mine was 5 day frozen embryo transfer and dont know what is wrong happened sir

    • @lipsasahu5771
      @lipsasahu5771 Рік тому

      Help me sir please... I don't know what to do now

    • @ivfexpert
      @ivfexpert  Рік тому +1

      I need more information to be able to provide you with intelligent advise.
      Can you send me more details about your IVF cycle ?
      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      PLEASE SEND ME PHOTOS OF YOUR EMBRYOS
      Can you please send me the printed treatment summary from your IVF clinic ?
      Please email this to me at drmalpani@drmalpani.com
      We look forward to helping you to have a baby !

  • @bharathkumar2065
    @bharathkumar2065 11 місяців тому

    Dear sir if we take egg 🥚from donor is it any guarantee... We can have healthy 👶baby...

    • @ivfexpert
      @ivfexpert  11 місяців тому

      The chances of getting pregnant with donor egg IVF in a good clinic are excellent, but no one can offer guarantees. Please have realistic expectations of what doctors can do - and what the can't !
      I agree donor egg IVF would be your best treatment option.
      We have an active donor egg IVF program . Read more at www.donoreggs.in/
      Dr Aniruddha Malpani, MD
      Malpani Infertility Clinic, Jamuna Sagar, SBS Road, Colaba
      Mumbai 400 005. India
      Clinic Mobile: 9867441589

  • @romanram3362
    @romanram3362 Рік тому

    Sir i want to marry my own sister-in-law she is my first cousin. In our family we dont have any genetic disorder from last 3 generations. Iam worried that if we conceive through normal procedure our baby may born abnormal by any genetic disorder. Sir can we go for IVF & PGD to avoid any genetic disorder for the baby iam really confused please guide me sir..

    • @ivfexpert
      @ivfexpert  Рік тому

      You can't because we don't know what genetic disorder to look for !

  • @romanram3362
    @romanram3362 Рік тому

    sir can i marry my own sister-in-law. We both love each other.we are the first couple in our family to marry through blood relation consanguineous marriage. we dont have any genetic disorders in last 3 generations & all are healthy.. before marriage we will go for genetic conselling & carrier screening test. after conceiving we can see the babies condition through scanning tests like NT, DOUBLE MARKER, TIFFA etc.. sir please guide me.

    • @ivfexpert
      @ivfexpert  Рік тому

      Yes- but these tests have major limitations. We can't test for everything !