How much caffeine in coffee?

Поділитися
Вставка
  • Опубліковано 20 вер 2024
  • In our first video about caffeine, Dr Rob Stockman extracts the molecule from six cups of coffee. Video also features Professor Martyn Poliakoff and Dr Samantha Tang.
    Necklace supplied by arohasilhouette...
    More about our Webby win: periodicvideos....
    More on caffeine soon...
    More chemistry at www.periodicvid...
    Follow us on Facebook at / periodicvideos
    And on Twitter at / periodicvideos
    From the School of Chemistry at The University of Nottingham: www.nottingham....
    Periodic Videos films are by video journalist Brady Haran
    www.bradyharan....

КОМЕНТАРІ • 2,2 тис.

  • @Braeden123698745
    @Braeden123698745 9 років тому +2389

    "When people are relaxed some of the best ideas come into their heads" That hit me like a ton of bricks because of course thats why our best ideas happen in the shower.

    • @alienweirdo8337
      @alienweirdo8337 9 років тому +161

      Braeden Hamson So they should install group showers in Cambridge, and apply the same rule of keeping it open in case people are getting ideas in there

    • @Mdxfiend
      @Mdxfiend 9 років тому +15

      Braeden Hamson They make dry erase boards for showers too I think

    • @Braeden123698745
      @Braeden123698745 9 років тому +4

      Jason Yingling​ If you have a plastic or glass shower it already is shower. But water splashing.

    • @Mdxfiend
      @Mdxfiend 9 років тому +6

      Wut? 0_o

    • @Braeden123698745
      @Braeden123698745 9 років тому +1

      Jason Yingling the water would wash the marker away, and dry erase works on any smooth non abosorbant surface

  • @guard13007
    @guard13007 8 років тому +728

    Loved the part about the coffee room not being allowed to close if there are people talking in there.

    • @unlink1649
      @unlink1649 4 роки тому +8

      I would like to upvote you but you have 420 upvotes and I can't ruin this

  • @DavidWorley94
    @DavidWorley94 9 років тому +308

    To anyone questioning the practical methods - this was only a quick demo. The guy knows what he's doing, honestly!

    • @LimaHotel807
      @LimaHotel807 7 років тому +18

      I'm glad someone here has some sense.

    • @JayMark2049
      @JayMark2049 6 років тому +4

      Jemima Puddleduck --- He could have used a proper solvent like DCM. It doesn't take any more time.

    • @persekarva6444
      @persekarva6444 6 років тому +14

      Industrially, caffeine extraction is done using supercritical carbon dioxide as a solvent.

    • @yellowjello2143
      @yellowjello2143 5 років тому +16

      Lol literally using these extraction/purification techniques in organic chemistry lab rn.

    • @pietrotettamanti7239
      @pietrotettamanti7239 4 роки тому +6

      I'd be okay with it being a quick demo if the objective was just to show that you can extract caffeine from coffee, but it clearly was to determine how much caffeine is in coffee. So it's reasonable to expect them to at least try to make a quantitative extraction (and maybe measure the volume they're working with).

  • @svenp6504
    @svenp6504 8 років тому +1961

    I was hoping he was going to snort it off the spoon at the end.

    • @JeoshuaCollins
      @JeoshuaCollins 8 років тому +138

      I'm willing to bet they didn't let that caffeine go to waste. But just... not on camera, man.

    • @frostedlambs
      @frostedlambs 5 років тому +17

      @@BillAnt maybe something a bit easier to make like 3-meo-pcp

    • @gianmariadri8515
      @gianmariadri8515 5 років тому +3

      I've personally done it a few times, but you really need to have more quantity in order to actually feel something. I suggest minimum 1g.

    • @gabeloftus9773
      @gabeloftus9773 4 роки тому +1

      @@BillAnt I love Pinky pink 😎

    • @aaronlandry3934
      @aaronlandry3934 4 роки тому +1

      Gianmnaut What’s it like to snort Caffeine?

  • @ObadiahtheSlim
    @ObadiahtheSlim 9 років тому +885

    At 80 cups of coffee, the water will probably be more toxic than the caffeine

    • @oscargr_
      @oscargr_ 5 років тому +18

      Nonsense

    • @apexmike849
      @apexmike849 5 років тому +115

      @@oscargr_ I think that he was attempting humour. Illogical, but very human.

    • @Ultiminati
      @Ultiminati 5 років тому +26

      It can be true by the way. But it depends on the time that it is being taken.

    • @أمادو-ذ6ف
      @أمادو-ذ6ف 5 років тому +75

      Actually .. I did the math and I was horrified .. some days I stay fo almost 24 hour or even more because I had work to do and the boiler is next to me .. every time my cup empties I get a new one .. thats about a cup every 15 to 25 mins .. add a ciggarette every time I have a cup .. I can see now I nearly killed myself a few times .

    • @vincentrobinette1507
      @vincentrobinette1507 5 років тому +15

      You might be right: imagine guzzling 5 gallons of any liquid in a day. It would take me some effort to drink more than 1 gallon in a day (assuming 8 Oz cups) That's 16 cups per gallon.

  • @boredbun9546
    @boredbun9546 3 роки тому +108

    _"80 cups a day is lethal. do not approach that al all"_
    *Me looking at my 20th cup of coffee* : Well, I am safe.

    • @mousey451
      @mousey451 3 роки тому +1

      I’m the same with drinking coffee 😂

    • @mapelaanjakoodaansuomeksi3432
      @mapelaanjakoodaansuomeksi3432 2 роки тому +3

      Didn't Fry from Futurama drink a hundred cups one day?

    • @robertwilloughby8050
      @robertwilloughby8050 2 роки тому +3

      Don't know about Fry, but Honre De Balzac drank 50 cups of strong coffee a day (and ruined his stomach in the process!) I think he died in his early fifties pretty much directly from his coffee consumption.

    • @arddermoutcramer5695
      @arddermoutcramer5695 2 роки тому

      ​@@robertwilloughby8050 50 cups? what a motorhead

    • @notmenotme614
      @notmenotme614 3 місяці тому

      “80 cups a day is lethal”
      Sounds like a challenge.

  • @loveja1234
    @loveja1234 6 років тому +91

    Whenever i spill something: "Scattering atoms everywhere"

  • @Lellistair
    @Lellistair 9 років тому +839

    I drank coffee every day in college and it did nothing for me except give me the super-shits

    • @Wyattttt710
      @Wyattttt710 9 років тому +201

      +Stephen MacLellan And yet you kept drinking. That's dedication.

    • @quicksilver5253
      @quicksilver5253 6 років тому +23

      I laughed with tears for 10 mins straight...

    • @becnal
      @becnal 5 років тому +30

      As you get older, that becomes a major reason to keep drinking coffee. Helps facilitate the process. :)

    • @tahdahloo4884
      @tahdahloo4884 5 років тому +3

      Oumaumau Kinda, It helps you go boo boo

    • @insolentish4529
      @insolentish4529 4 роки тому +1

      You're in a logical fallacy. Whatever you perceived to be a non-increase in energy may have been you at increased energy. Without the copy you may have been a wandering buffoon.

  • @julionica
    @julionica 10 років тому +315

    that ummhu at the end sounded so disappointing

    • @jaykhan8089
      @jaykhan8089 5 років тому +4

      hsahaha

    • @markgritzan2841
      @markgritzan2841 5 років тому +5

      Thought the same :D

    • @marcosmota1094
      @marcosmota1094 4 роки тому +7

      He put the work in and explained the process. He didn't need to be excited about doing 10th grade chemistry...did you read the part where he has a doctorate?

  • @mozkitolife5437
    @mozkitolife5437 8 років тому +233

    10:52 "Thank you very much."... "Hmm, mmm.... I'm off to do some rails.".

    • @Weisior
      @Weisior 7 років тому +4

      You would never want to sniff caffeine. Trust me XD

    • @mozkitolife5437
      @mozkitolife5437 7 років тому +10

      Now you tell me... 7 months later. I can't smell anymore.

    • @Weisior
      @Weisior 7 років тому +2

      Jason Axford Like I mean, 2c-p is so painfull, and taking a big line of clephedrone intra nasal is a "masochist trip" or like Jezus's "Cross way on Golgota" xD

    • @Weisior
      @Weisior 7 років тому +4

      Hopefully with a BIG reward after few minutes :D

    • @sporknife123
      @sporknife123 7 років тому

      you not supposed to snort phenethylamines :p

  • @mattwelshman590
    @mattwelshman590 8 років тому +1565

    7:09 "hah, kek.." 7:14 "oh.."

    • @Bcso591
      @Bcso591 8 років тому +47

      +Matt Welshman KEK

    • @Typisktmattan
      @Typisktmattan 8 років тому +69

      +Matt Welshman I guess was TOP KEK

    • @BaalFridge
      @BaalFridge 8 років тому +79

      +Matt Welshman rest in kek

    • @bobbyb9258
      @bobbyb9258 8 років тому +54

      Kek died.
      Me too I've noticed we're not allowed to laugh at a lot of things anymore since 2011.

    • @ralphdeguzman770
      @ralphdeguzman770 8 років тому +5

      it's keck

  • @atavernerpi
    @atavernerpi 10 років тому +417

    I'm deeply saddened that they did not recrystalize. :(

    • @PsychedelicFern
      @PsychedelicFern 5 років тому +43

      Ik totally skews the yield! What about the contaminates that were soluble in the ethyl acetate!!!

    • @nfactorial4074
      @nfactorial4074 5 років тому +2

      kenneth avanzino hahahahahahahaha

    • @gspecial3778
      @gspecial3778 4 роки тому +53

      5 years later I'm also deeply saddened they didnt recrystalize

    • @NN-DMT
      @NN-DMT 4 роки тому

      Me too

    • @aaronlandry3934
      @aaronlandry3934 4 роки тому +16

      I’m sad they didn’t do anything with the Caffeine. Adding it to some decaf or snorting it would have been how I used it

  • @5688gamble
    @5688gamble 10 років тому +336

    Caffeine is THE drug, every country has their favorite pick up. It is quite addictive too as like other drugs you develop a tolerance, caffeine blocks a major neurotransmitter, adenosine, which builds up naturally over the course of the day and makes you feel tired. Caffeine fits the same place as adenosine but does not possess the same depressant effect, this reduces the space for adenosine and blocks it's. In response your body develops a sensitivity to adenosine producing tolerance and resulting in a withdrawal syndrome if stopped abruptly. The vast majority of the worlds population consume caffeine in some form on a daily basis and most would feel a noticeable loss in energy without it. The vast majority of the population or earth therefore are at least mildly dependant on the drug. Great news for plants that produce caffeine, they have us hooked so we'll make sure they survive and reproduce. A clear symbiosis where two unrelated species provide a service for each other. It would appear that tea and coffee have lured us in like bees to nectar.

    • @SuperFalcoFalco
      @SuperFalcoFalco 9 років тому +1

      can you explain the step: "In response your body develops a sensitivity to adenosine producing tolerance and resulting in a withdrawal syndrome if stopped abruptly." maby a bit more in deep?
      Does that mean that if you dirnk a lot of coffee (or other caffeine) the body builds more receptors where the adenosine or caffeine can bind to ? Or how does this adaption occur ?

    • @5688gamble
      @5688gamble 9 років тому +9

      www.ncbi.nlm.nih.gov/pubmed/1865359
      www.ncbi.nlm.nih.gov/pubmed/8246157
      www.ncbi.nlm.nih.gov/pubmed/1846425

    • @manictiger
      @manictiger 9 років тому +4

      SuperFalcoFalco
      I don't know what causes tolerance to develop, but I know the withdrawal is not caused by chemistry, but by basic vascular physics.
      Coffee dilates the blood vessels in your brain and in response, your brain compensates by constricting them. When the coffee wears off and the dilation ends, your body is still constricting them. This is what causes the "caffeine crash".
      If I over-do the coffee (usually in excess of 28 ounces of Arabica), it causes a more immediate crash.
      Robusta is what most people drink and it is much higher in caffeine content.

    • @5688gamble
      @5688gamble 9 років тому +2

      manictiger The vascular effects do cause a headache as blood vessels that were being constricted dilate but I'm sure that tolerance and dependence develop to it's stimulant effects as it increases the levels of cortisone and adrenaline being released, as well as blocking adenosine which makes you feel tired, the body adjusts to any change in chemistry and when the caffeine is removed the adaptations remain leaving your body chemistry imbalanced again, while you adapt again you will have non-vascular withdrawal symptoms like fatigue in addition to vascular headaches.

    • @abberss
      @abberss 5 років тому +3

      That symbiosis is rather strange in itself as the plants with caffeine in them probably developed it as a toxic defense system against being eaten. It's just that humans are large enough to handle the toxicity of it while also being aware enough to appreciate its effects on the mind.

  • @kokorosenshi
    @kokorosenshi 9 років тому +120

    this video makes me want to be a chemist, not because caffeine was involved but how they removed the caffeine from coffee was really cool

    • @mindtreat
      @mindtreat 5 років тому +18

      Did you become a chemist btw?

    • @lindy6572
      @lindy6572 5 років тому +16

      MindTreat he became a drug dealer

    • @TheRudian2011
      @TheRudian2011 5 років тому +5

      depending the drugs you can combine those 2

    • @alphonsokurukuchu
      @alphonsokurukuchu 5 років тому +7

      @@lindy6572 must be in prison rn

  • @HerbertLandei
    @HerbertLandei 9 років тому +73

    I would really like to see Capsaicin extraction.

  • @hikaru-live
    @hikaru-live 8 років тому +35

    It is so cute seeing Sam gushing over that little necklace.

  • @punishedexistence
    @punishedexistence 11 років тому +534

    I remember doing this exact extraction in college, then when done, I had about 250 mg of pure caffeine, so what do you think I did with it? Like any young college student, I railed it up and snorted it much to the amusement of my lab-mates. Of course I regretted this action about 5 seconds later, my nose felt like it was on fire, and about 15 minutes later I thought I was gonna have a heart attack. But don't ask me what I did with the eugenol I extracted out of cloves... haha!

    • @MyLonewolf25
      @MyLonewolf25 7 років тому +115

      What did you do with the eugenol?

    • @420Khatz
      @420Khatz 7 років тому +68

      Dude what DID you do with the eugenol?

    • @zombiesandguns1
      @zombiesandguns1 7 років тому +13

      Tell us!

    • @harrickvharrick3957
      @harrickvharrick3957 7 років тому +29

      Yea forget about caffeine, what DID you do with Eugenol???

    • @iceni6409
      @iceni6409 7 років тому +4

      punishedexistence what

  • @trycensorthis3676
    @trycensorthis3676 7 років тому +12

    He's describing a very interesting body reaction, creating the antidote for caffeine. This effect takes place with all drugs consumed and it is not only linked to time but also to the place that you are used to take drugs.
    Drugs used in unknown areas will have a way stronger effect, because the body does not start the counter reactions to the drugs.

  • @learnmyname123
    @learnmyname123 4 роки тому +1

    That was the most genuine and endearing change of hearts I've ever seen on youtube.

  • @koshi6505
    @koshi6505 9 років тому +396

    That's some weak coffee.

    • @kevindifranco3494
      @kevindifranco3494 5 років тому +2

      Yeah I think Tim Horton's said their large Coffee had 80 mg.

    • @geometricart7851
      @geometricart7851 5 років тому +9

      yeah usually I drink 600 mg of coffee a day that would be like 36 cups of their coffee. I'd be peeing every 5 minutes

    • @redbloodedamerican2743
      @redbloodedamerican2743 4 роки тому +4

      My preworkout has 400mg of caffeine per scoop

    • @b.c.2281
      @b.c.2281 4 роки тому +8

      @@kevindifranco3494 Tim Hortons coffee isn't really all that strong. A large drip coffee from starbucks has 300-330mg of caffeine, which is kind of ridiculous when you consider that's roughly equivalent to a 4 pack of original red bull cans.

    • @sanderkinney2758
      @sanderkinney2758 4 роки тому +4

      @@geometricart7851 600mg of coffee or did you mean caffeine?

  • @1337fraggzb00N
    @1337fraggzb00N 8 років тому +155

    Curly hair professor rocks :)

    • @bobtheservant2647
      @bobtheservant2647 8 років тому +8

      its rick harrison if you didnt know and its his pawn shop

    • @1337fraggzb00N
      @1337fraggzb00N 8 років тому +1

      bob jim k

    • @95ern
      @95ern 7 років тому +3

      He reminds me of a older Dr.Strangleove.

    • @1337fraggzb00N
      @1337fraggzb00N 7 років тому

      Er n k

    • @xxxax31xxx
      @xxxax31xxx 7 років тому +6

      SIR curly hair professor :P

  • @NophexHD
    @NophexHD 12 років тому +4

    I'm only 13 but in the last few weeks I've been watching PeriodicVideos, I've learned more information on a decent portion of the periodic table than all the information I have learned in school in the last year. I've been interested in learning more about chemistry for a while and this channel has kept it very simple and very interesting as well. Thanks!

    • @ryann7760
      @ryann7760 2 роки тому +4

      now that you're 22, did you study chemistry in university?

    • @JAzzWoods-ik4vv
      @JAzzWoods-ik4vv Рік тому +1

      @@ryann7760 Not OP, but I started watching PV back in middle school, and I'm currently studying pharmaceutical chemistry

  • @CellRus
    @CellRus 8 років тому +6

    Ahhh, I remember doing the extraction and recrystallisation in my 1st year chem at uni! So nostalgic!

  • @Thumbsupurbum
    @Thumbsupurbum 9 років тому +5

    Caffeine was developed by nature as an pesticide. Everytime you drink something with caffeine, you're drinking pesticide. ;P

    • @qwerty687687
      @qwerty687687 7 років тому +5

      And water is a common solvent in industrial processes. Every time you drink water, you're drinking industrial solvent.

  • @crcaccounts
    @crcaccounts 9 років тому +27

    He said 30mg of caffeine for 6 cups of coffee? That's not right. Should be closer to 600mg.

    • @basmca1
      @basmca1 9 років тому +3

      for normal coffee its 25-58 mg per 100ml.

    • @crcaccounts
      @crcaccounts 9 років тому +12

      Fallingout EMS I was wrong, he said 6 cups yielded 100mg, but according to your math, 6 cups is 1419ml which yields 354mg to 819mg. That's either some really weak coffee, or he lost a good chunk of the overall caffeine during the process.

    • @SecularMentat
      @SecularMentat 9 років тому +1

      crcaccounts I'm guessing there was some loss in the process. It didn't show what preperation they did for the ethyl acetate extraction aside from the sodium hydroxide. Seems like if they had shaken it at that point it might have pulled more to the organic solvent layer. Then again there might not have been enough of a basic shift to force that to happen as well.

    • @lachlanallen341
      @lachlanallen341 9 років тому

      crcaccounts I've done a similar process to extract the caffeine for a chemistry subject, and we only got about 1/3rd of the original caffeine. I think probably the same happened here, and there was a huge loss during the process.

    • @JosephCatrambone
      @JosephCatrambone 9 років тому +2

      Variations in temperature, grind, and brewing time will also impart varying amounts of caffeine into the coffee.

  • @billtsirtsis7060
    @billtsirtsis7060 4 роки тому +14

    Einstein once called coffee the beverage of geniuses (Jerry Einstein from Peoria).

  • @TheEddzifyz0r
    @TheEddzifyz0r 9 років тому +82

    After drinking coffee for awhile, it doesn't make me hyper. It makes me rather relaxed but still a bit more 'awake'.

    • @Supermanohman
      @Supermanohman 9 років тому +3

      Eddzify CSGO that's what ADHD meds do too. It makes you "stimulated" but without the need to be hyper.

    • @chickenmonger123
      @chickenmonger123 9 років тому +1

      Vic Vinegar That is exactly right. Although, I have done many times the recommended dose, 400 mg and that will leave me buzzed and fidgety, talking a mile a minute.

    • @The_Gallowglass
      @The_Gallowglass 9 років тому

      chickenmonger123 So in other words you're drinking 30 cups of coffee? :P

    • @The_Gallowglass
      @The_Gallowglass 9 років тому

      chickenmonger123 I'll go for 8 with cream plz.

    • @randomvideosn0where
      @randomvideosn0where 9 років тому +4

      +Ó Slatraigh The coffee in this experiment is weak. Typical 8oz cup of coffee has 100-200mg of caffeine in it. People complain about kids drinking energy drinks and the terrible amount of caffeine but usually energy drinks have less caffeine by volume than coffee.

  • @Eric.Morrison
    @Eric.Morrison 11 років тому +8

    "Thank you very much"
    "Mm hmm. That'll be £600"

  • @lemaplestory
    @lemaplestory 9 років тому +12

    3:15 Sodium hydroxide shouldn't deprotonate caffeine
    Sodium hydroxide deprotpnate tannin and extract tannin to water-layer

    • @ColonelFlickage
      @ColonelFlickage 9 років тому +1

      lemaple shut up no one cares

    • @0xbaadf00d
      @0xbaadf00d 8 років тому

      +Xavier Brenneman you shut up no one cares about you not caring

  • @matts9371
    @matts9371 4 роки тому

    He isnt lying when he said some of your most brilliant ideas come to you in a relaxed state. I'm working on one of mine right now. I cant wait till its finished.

  • @Palifiox
    @Palifiox 8 років тому +3

    Strong coffee reduces the pain of jellyhead, once suffered by those who handled explosives containing nitroglycerin.

  • @LuiKang043
    @LuiKang043 11 років тому +7

    Lol! I love how Dr. Tang changed her mind after seeing the necklace!

  • @jl7986
    @jl7986 9 років тому +44

    9:02 looks kinda like saturn lol, without the rings

    • @aldionsylkaj9654
      @aldionsylkaj9654 9 років тому +1

      jl7986 Not if you imagine!

    • @jl7986
      @jl7986 9 років тому

      ***** nichilas cage ET kinda turns me on

    • @aldionsylkaj9654
      @aldionsylkaj9654 9 років тому

      jl7986
      Flying elephants turn me on!

    • @nehpetsaaa
      @nehpetsaaa 9 років тому

      ***** ur mum turns me on LEL

    • @nikkitamayo9929
      @nikkitamayo9929 7 років тому +1

      It kind of look like Jupiter, for me because of the shades of orange..

  • @edexnorth123
    @edexnorth123 7 років тому +1

    *It's not the coffee helping the scientists to win a Nobel prize but the aura created by brilliant people in that room while relaxing by drinking something to stimulate you, this does not necessarily have to be a cup of coffee.*

  • @duytdl
    @duytdl 4 роки тому

    Wow. 8 year old videos of this channel still blowing my mind. I liked the 3-story interlaced narrative as well.

  • @michaelbeary
    @michaelbeary 5 років тому +6

    8:01 Dr. Rob Stockman demonstrates his "cold finger"

  • @engineerisdead1303
    @engineerisdead1303 9 років тому +4

    What your body does is, the brain has special receptors that process a chemical that makes you tired. When the tiredness chemical enters the receptor you begin to feel tired. What caffeine does is, it's molecular structure resembles the tiredness chemical (I can't think of the name off the top of my head). So the caffeine begins going into these receptors, using them up so the tiredness chemical cannot get it. therefor reducing tiredness. But over time the body adapts and makes more of these receptors which over time makes the coffee useless. also if you stop drinking coffee after you drank coffee a lot, since you have more tiredness receptors then the tiredness chemical will have more places to go. This makes you go into a withdraw of sorts, being more tired that usual for a while until the body removes these extra receptors.

    • @emilychb6621
      @emilychb6621 4 роки тому

      Adenosine is the chemical you can't remember.

    • @engineerisdead1303
      @engineerisdead1303 4 роки тому

      @@emilychb6621 oh jeez this is an old comment

  • @realitea.avanova
    @realitea.avanova 10 років тому +4

    "You usually see it on people's coffee cups..." And I was thinking our office was particularly nerdy :D

  • @vycanon7057
    @vycanon7057 3 роки тому

    Its not so much the coffee in discussions but the fact that people across a department are communicating in a casual setting which increases efficiency. There was an Australian study into it but i cant remember it unfortunately to cite it.

  • @carlthecanadianjew4606
    @carlthecanadianjew4606 11 років тому +2

    In the words of Jess Pinkman, Mr. Stockman, you're a goddamn artist!

  • @imthescatguy
    @imthescatguy 10 років тому +75

    i only drink cola
    also, fry drank 100 cups but didn't die

  • @jesper10201
    @jesper10201 7 років тому +5

    Oh wow, the Kek clip just REEEEd pretty quietly after he mentioned it.

  • @user-kz8zr4si3i
    @user-kz8zr4si3i 5 років тому +9

    " if youve never had coffee, no doubt you will feel some effects from it"
    Ive been drinking coffee for 10+ years and every morning ITS LIFTOFF TIME BABYYYYY

  • @FishPit
    @FishPit 9 років тому +1

    I have the molecule tattooed on my calf. Used to work nights so was and still is a huge part of my life.

  • @nephdrummond3168
    @nephdrummond3168 6 років тому +1

    My chemistry teacher has a trinitrotoluene molecule tattoo, because he’s the bomb, and he was talking about getting a caffeine tattoo too. Since you mentioned how you see it everywhere.

  • @MelindaGreen
    @MelindaGreen 9 років тому +7

    Could someone make something like a litmus test to easily tell how much caffeine is in a drink? I'd buy that.

  • @Bourinos02
    @Bourinos02 10 років тому +20

    Caffeine is the only compound in coffee that is soluble in ethyl acetate?

    • @AguaFluorida
      @AguaFluorida 6 років тому +12

      The yellow colour of the solvent suggests not - caffeine is a white powder.
      (A bit late, I know.)

    • @elexs8754
      @elexs8754 6 років тому +4

      better late than never!

  • @way000
    @way000 5 років тому +76

    I feel like I'm listening to drug addicts explain why their drug isn't that bad.

  • @psycotria
    @psycotria 11 років тому

    If you were watching, NaOH is needed to deprotonate the caffeine, thereby making it more soluble in organic solvents.
    Making dry ice is easy. CO2 is simply sprayed into a bag, or a special block forming apparatus. All of the energy required has already been expended compressing the CO2 into the tank.

  • @looseele
    @looseele 5 років тому +2

    Caffeine: The most widely tolerated and accepted addiction in the world.

    • @vincentrobinette1507
      @vincentrobinette1507 5 років тому

      Agreed. the three most addictive drugs in the world: Caffeine, alcohol, and nicotine. They're so addicting, they CAN'T be outlawed. Everyone in congress, is addicted to at least one or more of these drugs.

    • @vincentrobinette1507
      @vincentrobinette1507 4 роки тому

      @moo While caffeine is among the least dangerous, it's still among the most addicting. Denying someone of their "morning cup of joe" would be absolute torture. fortunately, the withdrawal symptoms are not life threatening, and caffeine takes about 2~3 weeks to clear their systems. It's a psychological, rather than physical addiction. I don't know how long it would take for a lifetime coffee drinker to loose the need. Caffeine is pointless anyway. At first, it really works, then, you continue drinking it, just to avoid the lull you experience from withdrawal. After a few months, the caffeine is just maintaining the energy levels you would have, had you never touched the stuff. Save your liver, and just avoid it all together. All the studies on the benefits of coffee are based on anti-oxidants, and NOT the caffeine. The only studies showing ANY benefit to coffee or even alcohol, are sponsored by the purveyors of the vices, not independent studies.

  • @chasegilley1906
    @chasegilley1906 8 років тому +15

    the only thing I could focus on was that screen saver moving from screen to screen.

    • @Noodleude
      @Noodleude 8 років тому

      +Chase Gilley same

  • @drstrangelove09
    @drstrangelove09 9 років тому +10

    Wish that the caffeine powder had been collected and placed on a sheet of paper for viewing. Overall very interesting, indeed, though! Thank you!

    • @GamesFromSpace
      @GamesFromSpace 9 років тому +1

      You can buy pouches of it on ebay very cheaply. It looks like any other very fine white powder, maybe a bit heavier than icing sugar.

    • @nehpetsaaa
      @nehpetsaaa 9 років тому +3

      Joshua Pearce so it's a very fine white powder that gives the user energy and can make the consumer hyper.. so it's crack?

    • @TheAnon90
      @TheAnon90 9 років тому

      lol Crack is a hard substance that is smoked, cocaine is what you are probably referring to.

    • @GamesFromSpace
      @GamesFromSpace 9 років тому

      Great, now I have to do some chemistry and see if I can figure out how to make caffeine rocks.

    • @Hackanhacker
      @Hackanhacker 5 років тому

      @@nehpetsaaa yeah kind of .... its a drug !!!

  • @JuraIbis
    @JuraIbis 9 років тому +16

    I would like to know more about this "caffeine-blocking product" the body creates and how it works.

    • @yichern4351
      @yichern4351 5 років тому +4

      Im not entirely sure, but if I recall correctly, the brain releases a certain type of hormones that makes one tired and these hormones will attach themselves to corresponding receptors in the brain. Caffeine is able to act as a substitude for these hormones as they can attach themselves to said receptors too, blocking out the "tired" hormones. So thats why you feel more alert when you take caffiene. Eventually the body catches on to this though, so before your scheduled "coffee time", it will boost the production of these "tired" hormones, causing the body to feel very tired and craving the caffiene. Does that amswer your question?

    • @mitchelljacky1617
      @mitchelljacky1617 5 років тому +8

      Do you mean adenosine?

    • @nessunodorme3888
      @nessunodorme3888 4 роки тому

      I think it might just be extra adenosine.

    • @nickjohn2051
      @nickjohn2051 4 роки тому +2

      @@yichern4351 I thought it is related to upregulation of receptors site. I.e the brain create more receptors for caffeine to bind to. Thus minimizing the caffeine effect as the adenosine now can also bind to the receptors as the receptors number grew.

  • @chrisr9766
    @chrisr9766 Рік тому

    This an old video but one of the more relatable to many. I'm a metallurgical technician so have never had much to do with organics other than as sample mounting materials, coatings and reagents for my assorted etching compounds. I love this channel.

  • @jtpinnyc
    @jtpinnyc 4 роки тому

    It's amazing how much tidier his office was back in 2012

  • @JohnVKaravitis
    @JohnVKaravitis 8 років тому +242

    100 mg from SIX cups of coffee? These Brits must drink EXTREMELY WATERED-DOWN coffee! Mayo Clinic website says 95 mg to 200 mg from a typical 8 oz. cup of coffee!

    • @PeregrineHawthorn
      @PeregrineHawthorn 8 років тому +154

      Or the methods they used had a very low percent yield. In any sort of chemical process like this, you expect to loose a small amount of the product you're looking for. It's entirely possible that they only managed to pull a very small amount of the caffeine out of the original six cups of coffee.

    • @christine1902
      @christine1902 8 років тому +13

      A better way to analyze it is via HPLC, this extraction yields too little.

    • @RobertSeviour1
      @RobertSeviour1 8 років тому +2

      lose

    • @JeoshuaCollins
      @JeoshuaCollins 8 років тому +26

      How much solvent did they use? How long did they let it sit? Did they stir it or just let it sit for an hour or so?
      Basically, they didn't extract all the caffeine in the pot. I bet they didn't even get a fifth of it. And what they did get wasn't 100% pure, as you can tell from the coffee color in the end product (pure caffeine powder is white)

    • @perasturiaadastra
      @perasturiaadastra 8 років тому +20

      And if you believe the video he just added Ethylacetate once, normally you do it at least 3-4 times

  • @ideadlift20kg83
    @ideadlift20kg83 5 років тому +9

    That's a really weak coffee if it's 17mg per cup.

  • @cougarhunter33
    @cougarhunter33 10 років тому +6

    Didn't even get enough caffeine to chop up a decent line.

  • @Hyraethian
    @Hyraethian 4 роки тому

    Fun fact: Caffeine is achiral, It doesn't have a mirror version that might have different effects than intended. Its safe to accidentally put that pendent on backwards.

  • @bharathtony6087
    @bharathtony6087 3 роки тому +1

    "2:23 is holding my 3 cups of coffee" telling 6 cups.

  • @pruttelpot1
    @pruttelpot1 10 років тому +26

    Who knows if it is pure?
    Maybe there is something else in the end product.
    Why not use use Nuclear Magnetic Resonance to determine the purity of the product?
    And was the solution shaken when the product was seperated using the separatory funnel?
    Sorry, I am a scientist myself, and wonder what exact steps were taken :P

    • @geyza0711
      @geyza0711 9 років тому +3

      I would have snorted it to determine its purity! :D

    • @666Zwerg666
      @666Zwerg666 9 років тому +3

      Róbert Németh ah yeah! TIGHT TIGHT TIGHT!

    • @OeNoesRAWR
      @OeNoesRAWR 9 років тому

      Well he said he would of recrystallised it after his final step, this would of removed some impurities I believe. And based on the difference in colours from when he added the solvent to when he removed the bottom layer he had decanted properly off-screen.

    • @TheEnrisoto
      @TheEnrisoto 6 років тому

      Determining the melting point is quicker than NMR if you want to know if its pure or not ;)

  • @MrDannyArcher
    @MrDannyArcher 10 років тому +8

    I drink mountain dew, pepsi, coffee and tea everyday. I drink them quite alot really. One time I stopped drinking. On day 3 I went close to insanity. Anxiety, tiredness, nausea and general not feeling good. Caffeine withdrawal sure is scary. If you want to stop, do it slowly. Sudden withdrawal is bad.

    • @SoulDelSol
      @SoulDelSol 7 років тому +5

      MrDannyArcher prob related to your sugar intake as well

  • @NahkoWahko
    @NahkoWahko 6 років тому +3

    100 mg from 6 cups of coffee and im sitting here with a rockstar energy drink that contains 240mg caffeine

  • @HeavyProfessor
    @HeavyProfessor 8 років тому

    During my period of heaviest caffeine use, I was taking upwards of 2500 mg per day of reagent-grade caffeine powder. Definitely one of my favorite chemicals.

  • @magellanicraincloud
    @magellanicraincloud 11 років тому

    I immensely enjoyed this video not only because I love this channel, but I am also (if I do say so myself) a rather highly trained barista. One of the things you learn early on as a speciality barista is the different parts of an espresso shot. The fourth and final part (we divide into four. some do three) is dry distillates and caffeine. All the flavour you want comes out early. Caffeine is something good baristas want to limit, since it tastes awful.

  • @xXturbo86Xx
    @xXturbo86Xx 8 років тому +11

    Coffee has the opposite effect on me, i get tired and sleepy. It's chocolate that gives me a big boost.

    • @bobtheservant2647
      @bobtheservant2647 8 років тому +2

      then your buying coffie from a drug dealer no offence

    • @apexmike849
      @apexmike849 5 років тому +1

      Like my mum.

    • @executiveorder7146
      @executiveorder7146 4 роки тому +1

      Chocolate has caffeine in it and most dont know that some tea or soda has lots of caffeine in it

  • @sicktoaster
    @sicktoaster 7 років тому +4

    Outsmart your body, change the time when you take your coffee.

  • @TheTweakerTechnique
    @TheTweakerTechnique 9 років тому +197

    Coffee makes me have to poo.

    • @Jerz4lunch
      @Jerz4lunch 9 років тому +7

      +Jesus Christ, it only happens to me when I drink old coffee though.

    • @tohopes
      @tohopes 8 років тому +81

      +Jesus Christ
      Maybe eating poo would make you defecate caffeine. You should do a test and upload video.

    • @MrCheezeNip
      @MrCheezeNip 8 років тому +7

      +Jesus Christ Coffee is a laxative

    • @Lambda_Ovine
      @Lambda_Ovine 8 років тому +14

      +Jesus Christ
      It makes me pee and my pee smells terribly similar to coffee.

    • @turbotortiose
      @turbotortiose 8 років тому +11

      +Jesus Christ The reason why: Its a bean! Lots of people forget that.

  • @CaseNumber00
    @CaseNumber00 5 років тому

    I remember watching this program that said caffeine enlightened thinkers in the 1700 and 1800s. These were the times were great amounts of tea and coffee started to being imported to Europe. Also, scholars sometimes liked to meet together to discuss their ideas and coffee cafes were great place to meet.

  • @calebwieszczyk8247
    @calebwieszczyk8247 5 років тому +1

    At 7:45 he meant to say raising the boiling point. Lowering the preasure makes solvents more volatile

    • @vincentrobinette1507
      @vincentrobinette1507 5 років тому

      You're right, but he said it right. Lowering the absolute pressure lowers the boiling temperature. (boiling point) because, like you said, it makes the solvents more volatile.

  • @patriciahansenwithan
    @patriciahansenwithan 10 років тому +6

    thank goodness tequila is caffeine free.

    • @vincentrobinette1507
      @vincentrobinette1507 5 років тому

      2 out of 3 ain't bad. The 3 most addicting drugs there are: Caffeine, alcohol, and nicotine. They're legal, because everyone in congress is addicted to one or more of them. People don't even realize they're addicted to caffeine.

  • @kevinbyrne4538
    @kevinbyrne4538 9 років тому +19

    9:29 -- LOL !!! Well, gentlemen, now you know how to win a girl's heart (at least if she's a chemist).

  • @Deverlaid
    @Deverlaid 8 років тому +114

    KEK clips by Dr.KEK
    kek

    • @aeriumsoft
      @aeriumsoft 8 років тому +6

      +Deverlaid topkek is the best topkek. u wit me m8?

  • @tundras4ever552
    @tundras4ever552 4 роки тому

    I quit drinking coffee 6 years ago and have felt so much better! No more head aches and feeling tired

  • @sidritmeaj2157
    @sidritmeaj2157 5 років тому +1

    That is such a wonderful video! In fact,every video of "Periodic table of videos" is wonderful! As a great chemistry lover I am really fascianated! Greatest respects from Albania🇦🇱

  • @shunkaiy
    @shunkaiy 8 років тому +5

    this video makes me miss organic chemistry labs :)

  • @CLaw-tb5gg
    @CLaw-tb5gg 7 років тому +13

    17mg? That's some weak coffee. A Starbucks cappuccino has about 150mg.

    • @erinmayo5170
      @erinmayo5170 5 років тому +3

      For real. I'm an amateur chemist and I did this but with anhydrous ethanol and I recrystallized, which causes lower yields and I got ~430 mg from 5 cups.

  • @pirobot668beta
    @pirobot668beta 9 років тому +7

    Couldn't you have acidified the caffeine, crystallized out of solvent, then accounted for the ion? Sulfate?

    • @VICARI0S
      @VICARI0S 9 років тому +5

      Greg Gallacci Okay, Armchair-Chemist.

    • @pirobot668beta
      @pirobot668beta 9 років тому +17

      No arms on this chair!

    • @subh1
      @subh1 9 років тому +5

      Nathan Yeung how do you know he is an armchair chemist and not a chemist by profession?

    • @menkio
      @menkio 9 років тому +1

      Nathan Yeung look at your more recent posts... im going to assume your a poser.

    • @pirobot668beta
      @pirobot668beta 9 років тому +4

      I thought the issue was acidifying the base to drive it out of the organic solvent, then filtering solids out, rather than the tedious evaporation of solvent, and gunk stuck in your flask.
      Yes, you gotta account for the acid when you weigh the final result, but you still have solvent left, quicker results and less equipment costs.
      Chemistry has the same pressures over cost containment as any other profession.
      How much cost in one way over the other?
      That was the conversation I was trying to have.

  • @strizlivejmetlos
    @strizlivejmetlos 2 роки тому

    This channel is the one of the best chemistry channel's I've ever seen (besides Cooking with Walter White)

  • @proventure307
    @proventure307 4 роки тому +2

    6:55min great work, the double bond drawing in the middle of the molecule is wrong. It should not touch the ring.

  • @yishaqdavid2029
    @yishaqdavid2029 9 років тому +6

    6 cups of coffee is like 400mg? All they got was 30mg?

    • @yishaqdavid2029
      @yishaqdavid2029 9 років тому

      ***** I dunno how I got 30mg, but they still said 100mgs at the end.

    • @Ildarioon
      @Ildarioon 9 років тому

      Yiṣḥāq David All coffees aren't the same?

    • @alexeysaranchev6118
      @alexeysaranchev6118 9 років тому +4

      Yiṣḥāq David "a cup" is not an actual measurement, they should've told, for example the mass of the dry coffee used, or at least the amount of teaspoons. Also the coffeine amount is probably varying depending on type of coffee, place of growth and many other conditions.

    • @yishaqdavid2029
      @yishaqdavid2029 9 років тому +2

      Alexey Saranchev True, but where I live in Canada a cup is measurement. Not in a lab, but in the kitchen. I got mixed up. Anyway a cup is 250mls in Canada. That being said I am still wrong. When they said a cup of coffee I was thinking like whatever a large "star bucks coffee is". Anyway a large here has around 100mg of caffeine, but its much larger then 250ml. I Dont drink coffee so I cant tell you the exact size. You are totally right. I see my error.
      Now they are probably talking about those small white foam cups. Accounting for some loss of caffeine during the process and the very small foam cups, 30mgs does sound right.
      Thanks for making me rethink this. Nothing wrong with learning.

    • @damianp7313
      @damianp7313 9 років тому

      +Yiṣḥāq David coffee maker beaker is 2L 8 X250ml

  • @tfos993
    @tfos993 6 років тому +3

    The fact that there was a doctor kek

  • @TechMage299
    @TechMage299 8 років тому +3

    the editing in these videos is so perfectly times

  • @bink9113
    @bink9113 3 роки тому

    I think its so cool that these elements that we see play a part in everything that is. When they link up a certain way it makes such and such. But what tells them to link up in that fashion. There has to be a creator or a code atleast that tells these things to do this.

  • @anaml3879
    @anaml3879 3 роки тому

    Oh, love his hair. Currently my style while doing a chemistry class. It paint a big smile on my face. Thanks

  • @GueVonez
    @GueVonez 8 років тому +18

    Google says a cup of coffee has 95mg.....but you guys only got 100mg out of 6 cups!

    • @wupme
      @wupme 8 років тому +3

      +Broseff G a cup of coffee has around 10-40mg caffeine, some up to 60mg. But not 100mg.

    • @curtiswaters7415
      @curtiswaters7415 8 років тому +3

      +Broseff G A large cup of coffee from Tim Hortons (a Canadian coffee chain) has 170mg per cup. 10-40 is not realistic.

    • @Rabidum
      @Rabidum 8 років тому +4

      +Curtis Waters The rather big difference might stem from the fact that in europe the measurement of cups usually refers to teacups up to normal mugs which are around 200ml while the "cup" you refer to is around 700ml

    • @MrTwisted003
      @MrTwisted003 8 років тому

      +Eure Dudheit
      But the cup markings on the coffee pot are international.
      So, my [mug] doesn't hold [2 cups] of coffee, it holds 2 [cups of coffee].
      And still, 95 mg is not correct either, would be more like 10-50 mg...has a big dependence on what beans from where, that are blended to make your brand you drink. That's why coke and Mtn Dew have more than coffee. =D
      In-b4 my coffee shop has....espresso is different.

    • @TooShortPlancks
      @TooShortPlancks 8 років тому +2

      It's really dependent on the strength of coffee you make (i.e. more grounds, more caffeine can dissolve into the water) plus he was sort of off-handedly stating how much they had extracted. Towards the beginning, he did point out that caffeine is far, far more soluble in water than in an organic solvent, so there would be quite a lot remaining in the coffee, plus they were being quite rough and imprecise with the extraction, which can drastically effect your efficiency (easily halving or quartering the amount).
      That said, I would double check exactly which measurement size you got through Google - an average 'cup of coffee' is not the same as 'a cup of average coffee'.

  • @zapfanzapfan
    @zapfanzapfan 6 років тому +4

    Well, that put me in the mood for some coffee :-)

    • @efdbjon2114
      @efdbjon2114 3 роки тому +1

      same lol its 3 am but time for coffee now

  • @ThijsHagens
    @ThijsHagens 10 років тому +4

    This video gave me a craving for some good hot coffee, brb.

  • @gordonweiss7558
    @gordonweiss7558 4 роки тому

    Actually quite nice watching videos after more than 5 years.. the old youtube site at the picture where matt was holding a coffee makes me miss the old version of youtube.

  • @sureshm-ir5ev
    @sureshm-ir5ev 5 років тому

    hailing from india and seeing amazing person and learning chemistry as it is my fav subject and currently pursuing it feels lucky.

  • @bingola45
    @bingola45 4 роки тому +17

    "How much caffeine in coffee?"
    How much salt is in stew?

    • @Spocklee
      @Spocklee 4 роки тому

      This could go on forever

    • @bingola45
      @bingola45 3 роки тому

      Well that was wasted.
      A year later, and no-one saw the joke.

  • @Robostate
    @Robostate 9 років тому +12

    Dr. Tang produces an exothermic reaction. ;)

    • @aileenbos5115
      @aileenbos5115 9 років тому

      Bitter molecule (alkaloid C8H10N4O2) 4m53s 6:02 6:49 9:29 10:13 chemica S. Tang

  • @shoulders-of-giants
    @shoulders-of-giants 5 років тому +13

    10:54
    Thank you very much
    Mhm (>Òvó)>

  • @wordreet
    @wordreet 5 років тому +1

    I have had to forego caffeine in recent years, on doctor's advice, due to IBS. But I've also read that decaff coffee is actually only partly decaffeinated, with some brands leaving more than others. The USDA has regulations in place and theoretically decaf implies that 97% of the caffeine has been removed. But that probably depends on where the process took place in the world.

    • @kg-Whatthehelliseventhat
      @kg-Whatthehelliseventhat Рік тому

      I used to have a bad tummy... still do in some aspects. I have my 2nd illiostomy now. Since my operation I have learned how to better manage my tummy. If I may suggest 2 things.
      1 fermented pickles. The ones that must be kept in the refrigerator and made with salt and water. Not pickles that are made with vinegar. Sipping a few tablespoons of the juice is a great way to get a lot of probiotics.
      2 Simply Smooth coffee made by I believe Foldgers. This helped me back in the day where even a few sips of coffee would have me in severe pain. I think in comes in a green can. Simply Smooth is roasted in a special way that is very polite on the stomach. If you so desire maybe you could show your doctor and discuss it. I am now able to eat and drink things that used to destroy my insides. Roasting coffee and different brew methods is a hobby of mine.
      Perhaps the stuff mentioned will work for you, perhaps not. Please let me know if you try the coffee and what you think of it. I sympathise and empathise.
      May you have a great day.

    • @wordreet
      @wordreet Рік тому

      @@kg-Whatthehelliseventhat Thanx for the advice KG, I guess I'm lucky enough that merely avoiding an intake of high caffeine coffee all day does the trick for me. I don't get any discomfort, but I have recently improved a little more by cutting down on all the spices I used to like in my cooking. I still use turmeric and ground black pepper, (which I really love), plus I use plenty of red onions and or garlic. I also become vegan 4 years ago,which I forgot to mention previously. (I was veggie before since approx 1985) I've never smoked, and never liked alcohol since, at 3 yrs old, I toddled round after one of my parent's parties and finished off any tiny dregs left in peoples glasses. I was very sick shortly afterwards! Heehee! 😁
      Wishing you the best for this new year. 👍

    • @kg-Whatthehelliseventhat
      @kg-Whatthehelliseventhat Рік тому +1

      @wordreet You are very welcome. Thank you, and may you have a great new year as well.

  • @jacobjochem
    @jacobjochem 8 років тому +4

    can you smoke it?

    • @astone_ua
      @astone_ua 8 років тому +1

      +Jacob Jochem nothing special happens, I tried it)

    • @dilksjoel
      @dilksjoel 6 років тому

      Why?

    • @shoulders-of-giants
      @shoulders-of-giants 5 років тому +1

      smoking anything destroys the organ you breathe with
      so why would you if you have alternatives

  • @skylergarza8371
    @skylergarza8371 9 років тому +3

    Now the real question is, would that caffeine powder be safe to swallow?

    • @Dillfaro
      @Dillfaro 8 років тому

      +Skyler Garza Yes. You can also snort it. A little bit goes a LONG way. You are also chancing diarrhea.

    • @christine1902
      @christine1902 8 років тому +1

      +Skyler Garza Maybe, but it's made in the lab and whatever happens in the lab never goes into the mouth. Not even pencils, not even nails, not even boogers.

    • @apexmike849
      @apexmike849 5 років тому

      Not safe. Blindness.

  • @username42
    @username42 4 роки тому +3

    see you guys in next year when youtube has recommended this once again :))

  • @pomponi0
    @pomponi0 6 років тому +1

    Phew, close call, I drank 79 cups of coffee last night.

  • @salvagebar
    @salvagebar 7 років тому

    RIP Dr. Keck - your name will live on forever

  • @prwexler
    @prwexler 9 років тому +8

    How much caffeine in coffee? NOT ENOUGH!!!