LEV is inching closer! Rejuvenating mitochondria - Clinical Trials
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- Опубліковано 28 вер 2024
- www.skool.com/...
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I immediately think of tolkins elves, how few children they have, their longevity, and their patience and ability to spend time being artisans rather than rushing their lives.
Edit. Like some have said, and I totally agree, there also comes much grief amongst the elves
Bryan Johnson is the first true elf
@JohnSmith762A11B honestly that's one thing medicine can't really cure yet
And sadness, endless longing for times, places and people they have lost. Think of the first generation that may adopt anti aging therapies...they will have lost their friends, family, spouses, even the world they grew up in and knew the best will be long gone. Not everyone adapts easily to loss. What is a great boon to most, and to society at large may be a curse to some and a mistake to adopt. But younger generations will begin to feel it as time and chance eventually claims THEIR loved ones. I do think that, as beneficial as the prospect is and as essential to Human evolution, extreme life span extension will slow Human maturation and inject a powerful dose of melancholy into the Human "condition".
@@ericg6453 so true! There is so much grief
@@JohnSmith762A11B Basically every story of the Silmarillion
If you've ever been divorced.....we all mourn the loss of those years wasted!!! Bring it on!! Please, please, please give me 25yrs back!
soon we're gonna have "trans age" people.
I am 41 about to be 42. Because of Brittle Bones Disease I could never walk in my life and always lived on crutches and wheelchair. I hope before I reach 50 I get this therapy not only to reverse my age but able to walk normal like the rest.
Because of my disability I couldn't marry a decent woman and woman I married to divorced me because she saw I kept breaking and she didn't want to take care of me.
I hope you can be healed in the near future mate, looks promising
that sounds so hard. Hoping that you will be able to walk soon with these therapies.
Heartbreaking. It's cruel that we have people living with diseases like that. Really hope you can make it to LEV and start your real life.
@@ThomasTomiczek Idk maybe my bones can be replaced by some aluminum or steel metal?
Anything that makes me walk. All my life I saw everyone around me walking and with sad heart just sighed. I wanted to dress like a gentleman and walk before I die.
Regenerative medicine and LEV should get you to being your best self man, stay strong. @@vikasbedi82
Japan has been Fast tracking a lot of clinical trials for quite some time now and it usually goes nowhere. Just look at all those hair cures and cloning clinical trials. most are based on small animal clinical trials that have a failure rate as high as 99.99%.
Possibly a version of Super A.G.I can make the difference. As I believe theirs 9 to 13 Hallmarks of aging.
1. Genomic instability
2. Telomere attrition
3. Epigenetic alterations
4. Loss of proteostasis
5. Deregulated nutrient-sensing
(6. Mitochondrial dysfunction, is only one of many Hallmarks of aging)
7. Cellular senescence
8. Stem-cell exhaustion
9. Altered intercellular communication
Yep...we are not even close to the beginning of living forever even if that is possible (which I dont believe it is).
Imeglimin is already available in Japan ! Commercialization just started. I just bought some poxel shares after seeing this video :)
This is why Im fascinated by Michael Levins bioelectrics and electroceutical work. What he's doing is more like high-level subroutine calls rather than writing peices of code. Electroceutical in combination with drugs can orchestrate so many things simultaneously. For example, Levin has demonstrated starting and stopping cancer, controlling morphology, etc, all by controlling the bioelectric field. No genetic engineering or special proteins, just altering the bioelectrics only.
@@mjr7991to live forever we also need fatal accident prevention but I have reason to believe if we last another 10 or 20 years longevity escape velocity will begin. We need something to give us the amount of time needed to get the following antaging intervention.
I wouldn’t want to live forever. But I wouldn’t mind living 200 or 300 years and seeing all the things that humanity is going to accomplish. If not, then as a male in his mid 30s currently suffering from an undiagnosed neurological illness, I would want to at least live a normal lifespan where I feel healthy all the way up to when I die. What makes aging a disease isn’t that it kills you at the end, it’s that it makes you feel sick long before it kills you. Take it from me, y’all don’t know what pain and suffering is until your health is no longer intact. It’s indescribable.
Don’t know how that’s a problem. If I live to 200-300 and want to keep living well hey, it was a great 200-300 years.
I don't think I want to live forever, either. I do want to remain healthy and mentally fit until such time as decide that I'm bored enough to stop, though.
@@ThomasTomiczek I don’t think that’s a problem though. Then you just keep going.
I think if humans have a choice on when to pass on, we'll know when it's time. If at 300 yrs old you still feel the same way you do now, then that's probably the sign. If you change your mind by that time, well good, the tech by then will give you all the time you'd want.
@@ThomasTomiczekI can't understand either why someone would want a greatly extended life then choose to end it. Possibly they have some misconceptions. There's a lot I don't understand about people though
9:15 the irony of Dave telling us we're going to live for Centuries whilst simultaneously nearly slipping and drowning in a river!
😂😂😂😂😂
Yeah, I thought the same "we are going to live forev..." /*brokes neck/*
I had the same thought. Maximum universal irony: Having a fatal accident while disclosing a pivotal longevity breakthrough. The universe does have a sense of humor. Good thing he wasn’t driving a Segway.
@@paultoensing3126 🤣🤣🤣
@@alespider9905Redd Foxx had a skit, who is smoking cigarettes like mad and he said he wanted to keep smoking for the rest of his life and he had a friend who quit smoking and he told red fox that he was going to live 10 years longer than him and then read said well he was walking across the street one day about 2 weeks after he quit smoking he got run over and killed by a tobacco truck.
Reminiscent of the Segue inventor guy who Segued off a cliff.
Your videos give a lot more reasons to live. Thank you for this portion of enthusiasm
It's funny I was having this conversation recently because of your channel and these topics.
One of the things that the person I was speaking with had strongly believed was that he thought at some point he would just want to die, if not for anything else then just being on this world for too long. Similar to your grandparents being OK with death during seemingly casual conversation.
I responded by telling him it’s because they’ve spent maybe half or more of their lives continuously having a lower quality of life and sometimes becoming completely dependent. Of course they wouldn’t want to live after that? I said have you ever met physically and mentally healthy young people who’ve just casually wanted to die? Probably not and if he did it was rare.
You get your mitochondria from your mother. She got it from her mother. There must be a way to reset them.
This is a very interesting way of thinking about it - makes the concept seem not just plausible, but probable.
How does this follow? I'm not getting it.
@@popothebright Ageing has a lot of hallmarks. Your body creates new cells all the time, but they deteriorate as they divide and we age. Some magic is happening when a child is conceived. Even though the cells starting the embryo come from aged individuals, the child starts from zero. A lot of the anti-ageing effort is about understanding this process.
@@mrleenudlerI’ve never thought of this before
I just bought some poxel shares after seeing this video :)
Funniest but = When he speaks of living for eternity and then nearly falls in the river!
Yeah, that was great. "Somethin' will get ya". heh. Looking back on my life and thinking about all those times I could have died or been killed (at least 9 times) when a second or two made all the difference.... Cats have nothing on me.
I really appreciate this video...keep up the post labor grind :)
I wanna do things i want to do, hobbies, travel, learn new skills, experience new things, maybe see space or other worlds and finish certain tasks. I dont think i would wanna live forever. But 3-5 hundred years possibly.
We could travel by walking there. That would be quite eco friendly.
Who would want to give up being 27 forever?
20k years max probably then long sleep for a few million and reawaken
@@macrumpton perfect age for me would be me being 20-23 again
@@oranges557 yea, thats a big possibility for sure
I went back to school for my doctorate in my mid 30s in part because I felt that there’s a decent shot of getting an extra ten years on my total lifespan, thus offsetting the fact that I didn’t start my doctorate 10 years earlier. The point I’m making is that increased lifespan can cause people to rethink undertaking things that they previously thought it was too late for.
"Except for any Vampires out there in the audience~"
**silently backs into bushes like Homer Simpson**
Amazing news! Hopefully the trials go well and they help a lot of people manage their chronic diseases, even if it takes a few years before we see progress. But this gives me a lot of hope by 2030 that maybe I'll be able to try some rejuvenating treatment of some sort.
10 yrs Wow. I like you ! if I can stop aging at 60 yrs, I'll be happy. Still fit in my 50th. Hopefully, infinty life will come true...
Dude I appreciate your covering this topic a lot, ur doing great work man love ya ❤
I've got about 50 years left without any age enhancements, Hope I live to see at least 3-4 hundred though. There's so much I want to do and see and learn. One life isn't enough.
It is also possible to inject new mitochondria into your body. A study came out this year that found that that transplanted mitochondria migrate into cells on their own and they preferentially migrate into cells with damaged mitochondria.
Ooooh, that's exciting! You got a source for that?
@@mrleenudler I read about it on a longevity website called Lifespan
Yea source please and I’ll google it too.
@@croneyr Mitochondria Injection Alleviates Parkinson’s in Mice on the website Lifespan, by Arkadi Mazin
@@mrleenudler in the message i sent to the other commenter
Also, David Sinclair said his therapy was dirt cheap and that you could make it with common household products.
which therapy was that?
@@the42ndmeth
Having children has been the greatest joy of my life! If I could afford it I’d have dozens🤩🤔😍
Well you definitely should be excluded from the longevity treatment then
I think most people will continue to have children. Children bring too much personal fulfillment for it to just go away. Kids aren’t like 8 tracks.
Damn I like these future bio/medicine vids/talks. They are really a preview of all the cool things that will come soon
Agreed. Death will be optional. I am willing to try. 😁
I am 62. I feel the same physically and mentally the same as at 25. My labs and physical (just had) are perfect, for an 25 year old. I can lift 300 lbs, have stamina, no pains other than one thumb I have repeatedly broke. I eat a whole food diet and get a lot of exercise - I designed my life that way. Barring accident I anticipate getting to LEV.
Eventually we will even be able to restore from backup. Every anesthesia, far deeper than sleep, essentially death, I wake as a new entity and that has been fine. I do not know the difference.
The wealthy will get it first but jut like supercomputers in our pockets, everyone will have it, if they want.
“Just don’t die for the next ten years.”
Im going to put it out there. Alot of these do called extreme advanced, will not require AGI, just an ability to think, and problem solve with our getting tired, and creatively putting it all together. We are literally leaning over the edge of a cliff with everything we wanted at the bottom, and were only holding ourselves up with a pinky finger, that is getting tired. The age of A.I is the equivalent of every single person on earth having Einstein in there pockets, the potential from that alone, is insane. Were talking about the age of custom tech, were you can design a bot in mid journey, 3d print the parts, and install your desired LLM. This is we are right now.
I'm 53. I'd take ten years of life and be ecstatic. 43 is a universe of difference, even if you are active like I am. But 33 or 23? I think I might faint.🎉
Hi, I'm in my late 30s but been dealing with autoimmune diseases since my early 20s, so would be awesome to get younger too lol
btw, is your icon Yakumo Ran? (⋈◍＞◡＜◍) sorry for random question.
@phen-themoogle7651 I believe it is Yakumo Ran. I never played the games, but when I was researching the background for my D&D character, I modeled some of her traits and history. 😁
@@weredragon1447im 25 i never thought 50's would be physically exhausting i thought it happens in 70's or something
@@Kingkhan-qk2vk 🤣🤣🤣🤣
i love your videos! ❤️💯
11:22 That is an absolutely undesirable dystopian future.
David is one of the few people to leave Plato’s cave
The air and view from outside are just not comparable 🌸
We're in the plato cave watching him touch grass on our phone screens
@@SalamAnuar the grass is also in plato's cave but it might be closer to the entrance.
What a nice way to explain all the content really helpful
There still will be a problem of taking care of elderly/infirm. If not enough births, the problem persists. Its just pushed down the road.
If a person lived for 1000 years, and met a new person everyday, they would still not get to meet 1% of the global population.
People that think they will be bored if they lived up to, or more, than a 1000 years, just have limited imagination.
I'm skeptical. Very, comically optimistic, about so, so much.
we can Buy this Poxel Biotech on french market
Can you share how to order it? I am an MD myself.
Hey man I’ve just started to watch your videos, lemme tell you’ve been answering most of the questions that have been bothering me thanks for making these videos.also any advice for a 20 year old to be financially prepared for AGI?I’m currently a finances analyst.
Where do you look for most of your information and research?
Yea, I think maybe in 10 years time we might start to see some benefits. LEV isn't around any corner.
if I could just live to 200 yrs old id be grateful
Imagine 200 years mortgage...
Im 38 as well, it's amazing how aging catches up with you.. my poor knees 😬
David, all you have to do is stay alive for the next 10 years, then you are golden. My new anthem, Bee Gees. STAYIN ALIVE STAYIN ALIVE HA HA HA HA STAAAAYYYYYYIINNNNGGGG AAAALLLIIIIVVVVEEÈ
i’m actually concerned the “elite” will/do want to depopulate. so that they can have the earth to themselves. i feel that that’s coming and it has been difficult psychologically to have this fear.
What would good you that idea? Other then Bill Gates literally saying the world population should be cut in half, and smirking when discussing the "next pandemic". 🥨🚶♂️
When do you think will we be able to reverse aging? I mean not only longevity escape velocity (that might be close) which is about lifespan, but in the sense of really reverse the damage in our biological to the point that it is visually as well as functionally negligible. So people essentially can turn back to their early twenties
Those two are one and the same, more or less.
@@mrleenudler likely as an outcome but not a necessity for LEV. You could also just add one year per year by keeping old people alive for longer without rejuvenating them. At least for a time LEV could be achieved and maintained by that. But I think the goal should be true rejuvenation. With the expressed goal to reduce the amount of damage in the body to or below that of a 20 year old, so where it is functionally as well as visually negligible.
@@JohnSmith762A11B Fully agreed
@@ct5471 Gaining a year of life for every year lived is the same as stopping aging. I can't conceive of a treatment that can stop ageing without reversing it as well. That'd be like balancing on a knife's edge, neither growing older nor younger.
See work being done on partial reprogramming- already in Clinical trials.
Imeglimin acts on mitochondria and has received marketing approval in Japan
Great news! Rejuvenating mitochondria is a considerable step forward on the path to a longer, healthier life. Let's hope these clinical trials succeed and get approved worldwide soon.
My pragmatic side says the oligarch class will come up a way hide this or suppress it.
That seems pessimistic, not pragmatic. "Pragmatic" would be looking at all the forces acting to affect the outcome, not just one particular force.
Don't underestimate the power of pharmaceutical companies - with all their investors, lawyers, lobbyists, and pocket politicians. They have billions of dollars AND well-crafted political influence machines.
@@glenw3814 I don't know. I'd argue that the way its worked for the last 2000 years seems to be pattern where the elite exploit and take all they can. If you apply that historical notion.... it feels more pragmatic to have the expectation that the elite will act as they have over recorded history.
You're right; personal choice will play a big role. While some will opt for rejuvenation treatments, others may choose to accept ageing and eventual death. Regarding children, some will still want kids, but many may forgo that path with greatly extended lifespans. It will be fascinating to see how societal norms evolve.
What might that mean for someone being 30, 40, 50 … at the time of LEV, or perhaps when this mitrochondria drug is released (at 20 rejuvenation therapies might not be relevant yet, and after that more for cosmetic reasons for a time, after 50 mostly for health/ longevity reasons) . Like all 30 year olds look and feel 20 again, all 40 year olds like 30 and so on? Might it be that the impact is larger for old peoples, like for an 80 year old person it an equivalent of 20-30 years while for a 30 or 40 year old it’s more only 10 or so. Eventually we might all end up with more or less zero self inflicted accumulated molecular and cellular damage (what aging is) and all be 20-25 again more or less for ever, but how will the initial rejuvenation tipping point will look like for someone at this initial point, also depending on his current age at the time. Functionally as well as in terms of optics
Changing something as fundamental as the human lifespan (healthspan, too) will bring about a massive re-alignment of everything. Morals will change. Rules will change. Industries/economies/etc also will all change.
Everything must change to facilitate optimal preservation of the potentially limitless life.
the present population "problem" is falling birthrates below replacement levels. That's a REAL problem
kinda wondering, what does a starving person on mitochondrial rejuvenation therapy look like?
We might see some policies in place that basically make you decide: You are free to have children but legally you are not allowed to take this drug.
even if its 100$ a month anyone making minimum wage would still buy it
imagine the subscription fee
You should engage your community with questions. What projects would you undertake knowing you would live to complete them? What would you do differently knowing you will live to see the outcomes? Things like that. What would feel different in centuries of life? As a many century year old person returning seeing that tree you planted as a kid, is now a old giant, and a forest has come up of what used to be a field, how would you regard that?
We'd sure take better care of our planet.
I've been following life extension since the 1970s and there was no treatment or intervention that would be considered a standout. I thought it may turn out to be NAD+ but instead the standout is rapamycin, a senolytic. I read about 3 or so trials either going now or plans to begin later in the year. Maybe the mitochondrial substance will overtake rapamycin. I just hope something is proven safe and effective asap
Here's a thought: there have been some experiments with reverting somatic cells into stem cells. It is not implausible that we might soon have the ability to take a somatic cell from a man, revert it into a pluripotent stem cell, and then forward develop it into an egg cell, which could then be fertilized by the man's partner or even the man himself. This would allow everyone, regardless of sexual orientation or relationship status, to have their own biological children. Another promising technology is ectogenesis, where the fetus develops in an artificial uterus. This would free women from the physical discomforts and genuine mortal risks of pregnancy/childbirth, in my mind this would be a huge equalizing force because having children would suddenly be the same "risk level" for women as it is for men.
I hope we will live it. I studied a second time pretty late and finished with 37. I did not make my PhD because I felt too old and I wanted to make money. If I could live e.g. 1000 years, it would be nothing! You could study whatever you want!
There is already an American biotech company, called Mitrix, that is heading into human clinical trials to treat diseases of aging by doing mitochondrial transplantation. Mitochondria transplantation is not new. Its been used to treat diseases of mitochondria. What is new is to address aging square on using this as a regenerative therapy.
Plenty of things are cheap to produce yet are expensive as fuck. Insulin. Profiteers will always stand in the way of the greater good
Right, and it puzzles me when people say biological immortality is a bad thing. Why? Just because the idea of living indefinitely seems boring or meaningless to _some_ people doesn't mean it is absolutely meaningless. I'm looking forward to it. There's also the side benefits of reversing disease like you mentioned. Of course I'm gonna want that! It would be the biggest regret of my life if I never seized the opportunity to live life the way I've always wanted to, like when I was a kid and my time felt meaningful.
You cannot elongate the communal lifespan without a plan in place to curb the birthrate to match and then fall below the death rate. The span elongation percentage must eclipse the birthrate decline ratio significantly and as the technology gets better and the span continues to elongate the birthrate numbers must match up in reverse. You get a mirrored asymptotic function which approaches zero, and infinity.
You're wrong about people having children. Most couples want it. But the predatory laws and current society made them not been able to find the right partner.
Also our population is going to increase also by genetically engineered pets.
Everyone want a catgirl waifu. Or let's be honest an entire harem of them and their kemonomimi variations.
We're in the middle of a loneliness crisis and it'll be solve, Soon one way or the other.
@@sinnwalker I did say genetically engineered for a reason.
Robots GFs have a major problem.
The uncanny valley has a bottom.
And they are it.
What study are we talking about? Is there a link to check the details?
It doesn’t matter if the cost of production ends up being zero. They will price a drug such as what you’re speculating about higher than you or I will ever be able to afford, mark my words
Do you think longevity medication should be open-source? (If that is even possible.)
At the end of a recent video David welcomed feedback on whether the video is better. I wonder if there are some details there in the description or comments 🤔
Other fictional examples which to explore the concept of hyper longevity. Of them Pandora's Star hits closest to Altered Carbon's scenario, though I'd judge it a bit less grim.
'The Gentle Seduction' Short story by Marc Stiegler from 1989. Quite hopeful, core concept of making transitional steps acceptable.
'Pandora's Star' and 'Judas Unchained' by Peter Hamilton (Commonwealth Universe) Longevity via periodic rejuvenation treatments. Lots of perspectives explored in the society.
'Freiren:Beyond Journey's End' (Anime/Manga) Fantasy adventure setting focused on the perspective of a particular long lived elf with no clear limit on her lifespan.
I like the walks in the woods, gives peter Zeihan vibes
Personally I think consciousness is just a basic biological function. We see evidence of this in stroke patients who only eat what’s on the right side of their plate because they aren’t consciously aware of the other half. But then they can react emotionally to both halves of a photo. So it isn’t that they’ve lost the ability to see or either of their eyes aren’t working, it’s that their consciousness is somehow impaired. If that’s the case, we might be able to figure out how it works. As it was stated in the video, that would lead to true immortality.
So my timeline is- don’t die for 10 years>start using biological solutions to slow aging> if consciousness hasn’t been figured out, remove my brain from my body and continue to live in a machine that connects my ocular and hearing inputs to the internet> live long enough that way for them to extract and back up my consciousness
Even if backing up consciousness to preserve it isn’t possible, we may not actually need to back it up. All we would really need is a device that triggers upon death and transfers it somewhere else.
One thought that came to mind thinking about longevity is the idea of generational siblings. In the grand scheme, even though it's your child or parent, they are closer in age to you than people hundreds or thousands of years different from you that they're more your siblings than parent figure. Just a thought, but like you said, birth rates are likely to shoot down. Interesting thought nonetheless.
Ageing doesn't just happen to cells - there's the extracellular matrix (the scaffolding, if you will) that will also need rejuvenation. Very little progress has been made on that.
As excited as i am about this I doubt its gonna have that big of a impact, we may get 5 years tops, not 10-20, its only 1 piece of the puzzle
Im 71 but there are many immortalists my age and older. For examole Bill Faloon is doing a lit ofvself experimentation and seems to be doing well. Also Bill H. Andrews is an avid runner and recently ran a long distance in Death Valley. There are so many high profile people into life extension and physival immortality also George Church seems to be a believer. Hes famous for trying to bring back the wooly mammoth. (It wont originally be rhe pure species but a hybrid.)
In my honest opinion mitochondrial rejuvenation is only step no. 1 and we'll eventually have to find a way to move past our chromosomal limitation as well (i.e. Hayflick limit). It's not unrealistic to expect life extension treatments to extend human life to at least 200 years within the next 20 years, BTW.
This is also the most exciting field in biology at the moment. Folks like Aubrey de Grey and Michael Levin have been pioneering for a long time. Awesome to see they have some legitimate competition coming from Japan now; that'll only help them go to market with therapies faster.
I'm no biologist, but as far as I understand it, aging; as in decay of cells and organs, is due mostly to our DNA chromosomes getting shorter and shorter with each passing duplication. It's a rough shortcut but that's the idea.
Though I have no doubt mitochrondria boosting could change a lot of things, it might not be so much aging itself.
That being said, at 42, 50ish if it's on track by 2030, I'll take whatever they come up with by then lol
Interesting youtube though it was highly spectative and optimistic in my opinion. 10 years seems like a very short time span considering the glacial pace that medical research normally progresses. But we will see.
First we need to figure out how to accelerate the clinical trials using AI modeling (Alpha Fold 3) because we don’t know the side effects of rapid rejuvenation
100% agree, but then what ?
if altered humans / humans / superAi live side by side with different goals.
you might have 50000 superAi robots, what if one has "a really bad day" [?]
I am a middle class income 17 y old from Germany. Do you think I will live and be healthy over 100 or 150 years old?
how much have you looked into bryan johnson
Most of us are living under a gerontocracy, rejuvination treatments will get fast-tracked.
Population reduction in a consumer based world equals the destruction of society. Pitting this against someone like Peter Zeihan and his work would be a necessary analysis. I'm all for longevity but we are already seeing a push towards world War that is largely based on failing demographic structures. So not only will the immediate effects of aging have an effect on society, but the demographic knock on effects also need to be factored. It is not a simple nor pleasant conversation.
Anyone has links to resources regarding the trial he is talking about?
In the description
And this is why I've worked to have the money I do. So even if everyone can't have the longevity medications, I can. My number one goal in life is to not lose it, ever. The one thing I don't see this as being good for though is lazy and worthless people. We have many of those in our species. If you tell those kinds of people they now have forever to do whatever, then you've only incentivized them to do even less with their lives. Someone with the mindset of "I'll get around to it later" will now have the concept that they have an infinite amount of laters. As far as I'm concerned, not everyone deserves or needs to be around indefinitely.
I think you're right that once somebody does it for the first time, it becomes commonplace within a few years, just like aviation. We went from the Wright brothers to the first dogfight in 11 years. No way every nation doesn't dump billions into copy cat drugs
Same with AI. It's too valuable
you can buy poxel shares at any broker
I just bought some poxel shares after seeing this video :)
Such an interesting perspective
I'm not asking for a finantial advice, but if you would invest in AI which sectors would you chose? I'm betting on Semiconductors, Nuclear/fusion, and Automatization. Is it a good call?
This is incredibly interesting, especially in the context of space exploration, and for many reasons. We could consider that not only would we survive long journeys but also live long enough to colonise and pass on our knowledge to future generations. Mars suddenly seems like a realistic proposition
Mars has always been a realistic option. It's ~6 months to get there. You don't need biological immortality for that...
Well a good follow up to this video then would be an exploration of what humanity will be like if we all live forever. IF almost nobody ever dies and almost nobody ever is born... we will become a society of eternals. What would this mean for progress and social change?
I'm wondering if there will be attempts to control the masses by requiring each of us to tick certain boxes to qualify for such a treatment. As in one's religion, race, intellect, criminal record, geo-location, limited per cent of qualifiers by district/city/State/etc., politics, voting, income, ability to sustain oneself economically, etc.
The perspective 'we riot, we get the drug too, not only the rich' is an interesting take. Looking at global context, it's a whole different thing...what about the middle east? What about the poorer countries of the world? I guess globablly speaking, we may become the meths.
Speaking about the global context, many tyrannies fall because of new generations. Without a new generation, the Potential for change also wavers. Also the potential of more innovation, I would assume, if there are less young engineers, scientists etc. challenging old ideas, especially if the status quo is stronger than ever, since more 'older' people living it.
The delicate question is: is it better to take Sumitomo's medicine or buy Poxel shares, in France....in the first case you may be better, in the second, it will be your financial health which could improve ....!🤑
You have also the work of David Sinclair with epigenetics which might be able to rejuvenate human bodies.
Altered Carbon was dope!
Kind of wonder if you have a blindspot about how people will behave towards having children in the future. The argument that we've already solved the problem because in modern society are having way less children doesn't seem to apply to a society where we would have much more time and resources. Having children, and not just one or two would probably be way more attractive in a world where you don't have to work, you are in great health and you have loads of resources to provide them. I hope you're right that people will just choose of their own accord to just have a couple kids, but I think you need to put more thought into this issue.
Consider places that have very high birth rates do so partly to have a team to support them I.e. grow your own workers… consider this will reason will become obsolete with AI/robotics.
Overpopulation worries are completely unwarrented at this point. We're reaching the point that space industries are possible amd it'll soon be followed by colonization. All we need is another gold rush and we'll be looking at emptying half the entire EU youth population for each new area, and we're looking at hundreds of great places to put down mines, not to mention the infinite possibilities of mass manufacturing O'niel cylinders for effextively infinite colonies just in Earth's orbit.
If we don't get birth rates up, even with infinite longevity, we're looking at population depletion on par with 'humanity has declined' in only a few centuries.
What if there’s a credit incentive program I. Which if humans get creative productive things done get incentives like credits of nano mitochondria rejuvenating drugs
Working with each individual DNA,and free healthcare for people that don’t do the work only consume a get UBI and only survive with that, but won’t get the liquid unless they do the work,
there are plenty of drugs that are cheap to make but insanely expensive to buy. you really think any drug company is going to give away a gold mine like life extension meds for the cost of production? no they'll milk the 1% for all their worth because they know they'll pay it and no one else will ever have a chance.
Don't Die! The best strategy
In reality, if you're looking at doing anything don't plan it for 100 years from now. Just do it now. There is no 10 year guarantee coupon given to you at birth.