Noise-Bias & Contrast-Noise Analysis in Medical Imaging

What's Noise in imaging? What's Bias? What's Mean Squared Error (MSE), and how does it relate to noise and bias? What are Noise vs. Bias Trade-off Curves? What's Contrast? What's Contrast-to-Noise Ratio (CNR)? What's the Rose criterion? What's the Contrast Recovery Coefficient (CRC)? How do these metrics relate to each other and different image reconstruction & generation methods?
0:00 Introduction
0:25 Three generations of image analysis
3:27 Noise and bias metrics
4:08 Mean squared error (MSE)
8:36 Impact of image reconstruction/generation methods on metrics
10:19 Noise vs. bias trade-off curves
18:45 Contrast and contrast-to-noise ratio (CNR)
20:08 Rose criterion and how it relates to CNR
21:10 Contrast vs. noise curves
23:05 Contrast recovery coefficient (CRC)
23:54 CRC curves
25:17 Noise correlations and task-based analyses
27:39 Summary of key concepts