A Dummies Guide to Testicular Germ Cell Tumors

Testicular germ cell tumors are encountered infrequently in practice but the diagnosis you make has a significant impact on patient management and prognosis. Learn a simple yet insightful approach to diagnose these tumors. This video features Dr. Rajal B. Shah, an expert genitourinary pathologist, educator, textbook author, and author of many landmark papers on prostate and other urologic cancers.

[@raghumenon9966]

Very good presentation, clearly explaining all key points

[@louiselynggard6834]

Thank you for this excellent lecture from a Danish resident

[@tinocasadeitherezo6063]

Wonderful lecture, indeed! Hoping for more! Thank you.

[@sambitahmed]

Awesome Rajal🙏

[@hamidohimo1]

Great as usual, many thanks and much appreciated

[@niloufarpourfarrokh5693]

Excellent. Thank you

[@shuchitasharma5151]

Excellent lecture sir. Please do more series on renal system.

[@LHA100]

Excellent lecture and very useful . Thanks.

[@TheSlimz1]

Very informative Dr, Thank you

[@seoyoungpark9253]

Thank you for your effort This was so informative!

[@prachinichat9439]

It was very informative...thanks for the very practical approach 👍

[@ashrafzubair3270]

This was an excellent lecture... Very simple and lucid... No confusion... Please keep up the great work...

[@premmaharjan2469]

Thank you

[@alenwargis9744]

Thank you Sir. 🙏🙏

[@muslimalhamdulillah3739]

Thank you very much

[@redaelhawary8815]

Excellent lecture sir.

[@marmoramonty6486]

How you makes everything so simple amazing explanation

[@theyeetboyz6838]

Very good lecture

[@humaarshad3044]

Excellent lecture, very nice and easy way of presentation , very helpful for revision

[@PatriciaHernandez-ov7bg]

Wonderful lecture! Thank you very much Dr. Shah!

[@rajalbshahExperturologicpath]

Thank you, Patricia! I appreciate your feedback. Please also share the channel with your colleagues

[@rahmaabdulkadir1196]

Helpful

[@shilpygupta1645]

Nice

[@ncorry8491]

Thanks very useful for residents. Would you consider using virtual slides in the future for cases?

[@idageorge5393]

Thanks for the effort

[@rajalbshahExperturologicpath]

Thank you!

[@dr.sunitimishra1346]

Excellent lecture. Thanks very much for sharing your knowledge with us.

[@rajalbshahExperturologicpath]

Thank you, Suniti!

[@basmazaki254]

Thank you so much !

[@rajalbshahExperturologicpath]

Thank you. Basma!

[@FilipSokol]

Excellent presentation. Thank you very much.

[@rajalbshahExperturologicpath]

thank you Filip! Appreciate your feedback!

[@priamsai2011]

@@rajalbshahExperturologicpath Sir, would you mind sharing your mail id pls. Need some more clarification on GCT. kindly provide.Thank you .

[@nilampatel7144]

Excellent and easy to understand presentation sir. Thank you.

[@rajalbshahExperturologicpath]

Thanks, Nilam!

[@priyankamaheshwari5033]

Wonderful lecture Sir thank u soo much

[@rajalbshahExperturologicpath]

Thank you, Priyanka!

[@amritachatterjee8068]

Thank you very much Sir. It's a great presentation for us residents. So helpful. 🙏

[@rajalbshahExperturologicpath]

Thanks, Amrita! I appreciate the feedback. Please share this channel with your fellow residents as well

[@amritachatterjee8068]

@@rajalbshahExperturologicpath definitely Sir. Will do that.

[@VainIllusions]

Very good lecture. Thank you

[@kaushiksaha1473]

Thanks for such an excellent presentation. Would you please consider making a video on Adenocarcinoma of Bladder/ urothelial tract? Regards 🙏

[@rajalbshahExperturologicpath]

Thank you, Kaushik! Appreciate your feedback. Thank you also for the new topic suggestions.

[@vigneshk468]

Doctor ,
29 age
Bilateral testicular mictrolitisis what kind I do pain come and go classic stage with varicocel also

[@msteel2986]

This was an absolutely fantastic presentation. Will improve my practice quite a lot. Thanks very much

[@rajalbshahExperturologicpath]

Thank You very much for your feedback! Please check out other videos in the channel as well. There are many other practical practice oriented topics

[@tinocasadeitherezo6063]

Is the lymphovascular invasion at the spermatic cord margin considered a compromised surgical margin?

[@rajalbshahExperturologicpath]

Typically No. You require invasive cancer at the margin to call a positive margin...

[@wallendegen1]

Hello, again thank you for this wonderful presentation.
When does one consider an epidermoid cyst as a distinct entity that is not part of a teratoma ?

[@rajalbshahExperturologicpath]

wallendegen1 I would consider epidermoid cyst diagnosis when I don’t see any changes suggestive of GCNIS or perturbed tests in the background. Also I would be careful of making this diagnosis in post pubertal setting.

[@rajalbshahExperturologicpath]

Thank you for the feedback!

[@tinocasadeitherezo6063]

In case 2, how do you explain the elevated AFP?

[@rajalbshahExperturologicpath]

As I said earlier, embryonal carcinoma can have elevated AFP level. Usually mild elevation

[@marisa632]

Hello sir. Thank you for another wonderful lecture… full of practical points. May I ask if you grade testicular immature teratomas in your practice? Is it acceptable to use the same grading system as in the ovarian immature teratomas or should I give only the percentage of the immature component in the testicular setting?

[@rajalbshahExperturologicpath]

Testicular teratomas in post pubertal patients are malignant regardless whether they contain mature or immature elements. Grading is not recommended. Thank you!

[@marisa632]

Thank you Dr. Shah!

[@akanksham1920]

Sir, what about teratoma immature neural component in prepubertal setting? Is it still considered prepubertal teratoma (which is benign?)

[@rajalbshahExperturologicpath]

Akansha, good question. Typically, prepubertal teratoma which is considered benign has mature skin and appendage components of ectoderm, rarely cartilage and lacks GCNIS or impaired spermatogenesis. If there is truly an immature neuroepithelium than I would consider it as a potentially malignant

[@akanksham1920]

@@rajalbshahExperturologicpath thank you sir

[@tinocasadeitherezo6063]

Wasn't the elevation of the AFP to occur in yolk sac tumor, at least preferentially?

[@rajalbshahExperturologicpath]

Yes, that is correct. AFP elevation is typical of yolk sac component. Embryonal carcinoma also may also demonstrate slight elevation

[@tinocasadeitherezo6063]

Excuse me for another question: in case 3, what would be the diagnosis, since you shouldn't use the word "mature"?

[@rajalbshahExperturologicpath]

Malignant germ cell tumor, comprising of teratoma elements ( post pubertal type)