Sulfur Ylides - Corey-Chaykovsky Reaction (IOC 42)

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  • Опубліковано 17 гру 2024

КОМЕНТАРІ • 24

  • @ThatChemistOld
    @ThatChemistOld  2 роки тому +25

    Are the practice problems that I have been assigning sufficiently difficult, or too difficult? React to this comment with a like or a dislike to let me know!👍👎

    • @劉樂山
      @劉樂山 2 роки тому +1

      I can't tell, cause I'm a math major. But watching your video makes me learn a lot.

    • @levtrot3041
      @levtrot3041 2 роки тому +1

      Write a problem book

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому +1

      @@levtrot3041 if a publisher reached out, I would entertain a conversation on the matter

    • @sirjaustin9140
      @sirjaustin9140 2 роки тому +2

      they are on the more difficult side of the problems but difficult problems make it so that you have to review the previous lectures sometimes again and learn stuff again

    • @madansharma2700
      @madansharma2700 2 роки тому

      The problems are well balanced.

  • @rokasvilniussidlauskas1043
    @rokasvilniussidlauskas1043 2 роки тому +3

    Discovered your videos recently and I love it! The topics are interesting, the problems are great - keep up the great work!

  • @AsdfFdsa-gp5qg
    @AsdfFdsa-gp5qg 2 роки тому +4

    I’m probably one of the last people you’d consider for a target audience considering the last time I looked at chem was 6-7 years ago in AP chem, but wanted to drop in a note that I really enjoy hearing about this stuff, even if I don’t understand a good 80% of what’s going on. Your delivery and respect for your audience in these are very refreshing!

  • @giovannipelissero1886
    @giovannipelissero1886 2 роки тому +1

    Undergrad here (European equivalent). I didn't study this reaction and others in your channel too (even if I passed every ochem exam) so it's always nice when I check your channel. Since organic chemistry is my favorite study field I basically discovered an hidden gem in your channel. Great content and many weekly uploads.
    Keep up with the great work!
    From Italy with love.
    Btw I've already switched to the other channel. Good luck.

  • @bdnugget
    @bdnugget 2 роки тому +7

    With NaH it scales horribly since the dimsyl sodium you form is already annoyingly viscous and hard to stir, that combined with bubbles from H2 caused my upscale from 10g to 100g yield almost exclusively byproduct crap while on 10g scale it was just a few procent. KOtBu was really great, not only does it not foam, the tBuOH it forms is a great cosolvent and makes everything way more pleasant to stir :)

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому

      Glad to hear it, shout it from the rooftops!

  • @fatistef
    @fatistef 2 місяці тому

    Genial gracias, tenía un problema igual al del minuto 14:13 y tenía duda de que si era posible formar un producto así 😅

  • @haryhilic4932
    @haryhilic4932 2 роки тому +2

    5:43 a small mistake, S=O should not dissappear

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому +1

      yeah I mentioned it in the description - I caught it for the thumbnail, but only after I already recorded

    • @haryhilic4932
      @haryhilic4932 2 роки тому +2

      Oh I read the comments but didn't check description my bad

  • @madansharma2700
    @madansharma2700 2 роки тому +1

    Will (Me)3SO(+) not deprotonate using LDA / THF Or am I missing something?

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому

      it should, but I haven't seen that in the literature

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому

      try it out and report back!

    • @27.minhquangvo76
      @27.minhquangvo76 Рік тому

      @@ThatChemistOld I saw it in a worksheet and a friend of mine asked to propose a mechanism. Fortunately, it was exactly as you taught me.

  • @TheSiliconchip
    @TheSiliconchip 2 роки тому +2

    FOUND: DOI:10.1039/P19830002913

    • @ThatChemistOld
      @ThatChemistOld  2 роки тому

      yeah this is my third reference in the description - this was the earliest example that I could find, but they don't reference any other paper using the same methodology, and they don't comment on why they chose the conditions they use