Video 9 White Blood Cells Types and Functions
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- Опубліковано 13 січ 2014
- 09) White cell types and functions
While white cells vary in size, generally they are the largest cell type found circulating in the blood. They live in the lymph system, where many are stored. They circulate in the blood. And they can be found in tissues throughout the body, always ready to spring into action. As a group all the different types of white cells together make up less than one percent of total blood volume. Some white cells live just 18 hours, while others live for many years.
Now let's take a closer look at the different types of white cells and the role each plays in protecting the body. There are five major groups of leukocyctes: basophils, neutrophils, eosinophils, monocytes and lymphocyctes. Each of these cells is equipped to match a specific type of antigen or invader.
Let's start with basophils. These white cells defend against parasites and bacteria by releasing histamine and heparin, which is a blood thinning substance. Histamines are what cause allergy symptoms, such as itchy skin, watery eyes and a runny nose. Basophils are not antigen specific, meaning they don't have to determine what the invading substance is before taking action. They spring into action any time a foreign substance is detected.
Next are neutrophils. This group of white cells target bacteria and fungi. Neutrophils are the most plentiful white cell found in the blood. They usually respond and multiply very quickly, resulting in high white cell counts.
The third major group of white cells are eosinophils, which target larger parasites, such as worms. Eosinophils also moderate allergy inflammation responses.
The fourth major group of white cells, are the lymphocyctes, which work the front lines to identify and destroy foreign invaders. In this group there are three primary types of cells: B-cells, T-cells and natural killer cells. 75% of lymphocytes are T-cells, 10% are B-cells and 15% are natural killer cells. B-cells circulate on the front line in our blood and lymph systems as well as in the tissues throughout the body. They primarily function to identify foreign invaders. B-cells are associated with antibodies, which we'll learn more about in coming videos.
T-cells are white cells that mature in the thymus (part of the lymph system) and then migrate to the point of invasion when called into action. T-cells help surround, bind to and then kill off the invading cells. T-cells also provide an essential regulatory function to ensure that the immune system is not over reacting or under reacting to a pathogen.
Monocytes are unique in that they are partially differentiated white cells, meaning they are not fully mature. They are stored in the lymph system, circulate in the blood and migrate to tissues throughout the body, where they mature into one of two types of cells: macrophages or dendritic white cells. Macrophages ingest and break down both invading microbes as well as infected human cells. Dendritic white cells act like messengers taking the broken down antigen material and presenting it to other white cells, typically B-cells, which will identify the antigen and then trigger a chain reaction that helps activate T-cells.
Monocyctes are also involved in the production of cytokine protein molecules, which carry signals between cells. There are many types of cytokines. One example tied to monocytes is histamine, which leads to an inflammatory response to an antigen. In coming videos we'll get to see more about how these white cells work together.
Its cool to see people studying for A&P over 8 years ago watching this video. Very Helpful
Im addicted to this for things some reason
Great video but you didn't explain natural killer cells :(
Yess :'(
2:22
Great explanation.. Simple and easier to understand.. good job.. And thanks for the effort
Great video, helped me a lot with a project I had to do. We even used this video in class
Finally, someone that made it nice and simple!
Thanks for making videos like this that he'll students to learn and know more facts
very well explained. thanks !
pretty good and forward , thanks man !
Excellent explanations and graphics. Thank you. God bless.
Great Video!
Fascinating!
This really helped me with my prodject I'm doing for school this is a good explanation
Hello
very informative! Studying for my A&P exam and trying to grasp this concept
Christina Huffman how’d you do? Lol
Perfect! thank you so much!
Excellent video. Learnt more in 4 minutes than all the crap from the scientists on the tv and news. Thanks a million.
thank you for the information
easy to understand.thank u☺
Very well explained
Thank you so much, precise and clear.👍👍👍❤️😄🙏
I loved this video .
Thank you!
Terrific overview, thank you!
GREAT!
That’s really helpful thank you very much
شكرا لك
thanks!
nice and clear
thank you so much 🙏
good video
thanks a lot
Thank you i got a clear idea
Very helpful
thanks
Good, for my kids to learn!
thanks lad
LMAO i cant focus cus of hataraku saibou
I feel it brah
wbc are my most favorite cells in my body❤
Great video
Cool video. But I still didn’t get what the functions are sadly, but hey NICE VIDEO!
Ty sir
Ooooh I Studied these things in my previous year quite differently and wrongly 😢
my neutrophils result is 43 .. the normal range is 42-75 .. any explanatio
He does mispronounce things on occasion but the animations are helpful. Is it me or does his voice sound like Bill Murray?
how can I reference this?
!Que pesar que no hablo inglés¡ Pero creo que es un gran mensaje.
Explain NK cell in a separate vieo
parasitosis cause eosinophila that cause asthma or what ?
I just can't understand the relation between the eosinophil and allergy !
great video tho'
thanx ")
+Yasmine Ghariani I'm not a doctor, but I believe the problem is caused by the B-cells. If they produce IgE antibodies, the eosinophils will respond instead of the killer T cells or macrophages. I have heard that the white blood cells respond like this or cause asthma is because the allergins, for example pollen, represent proteins that are similar to that of a parasite or fungus so your immune system responds like it's a parasite or fungus (or it's just genetics or something, but this would be my best guess.)
1- unharmful Antigen enters the body
2-B cells bind to it and be activated, now called Ag specific B cells
3-Ag specific B cells undergo proliferation and differentiation to plasma cells and memory cells
4-plasma cells produce IgE that attaches on Fc receptor on mast cells (found in tissues) or basophils (found in bloodstream)
5-now Ag bind to IgE on fc receptor on either mast cells or basophils and induce degranulation which releases histamine and heparin
6 - histamine cause inflammation, smooth muscle constraction, vasodilation ((anaphylaxis))
👍👍
This video is actually really confusing because he doesnt go in order and explains monocytes at the very end.
Monocytes are not a part of leukocytes and should be grouped together with the myeloid progenitors.
I’m just interested in biology
Same
Wtf,this is like military....Front lines,roles,types...damn son
No explanation of natural killer cells or how macrophages in tissue are location specific.
Wbc 36 percentage it's noramal
Why does he mispronounce so many of the cell names? It's "dendritic" not "dendric!"
Great ! 😂
You should've specified that it's not for Med students.
Thumbs up if you are here from Christine Woods' A&P 2 class.
you writing error 'lympocytes' under the video. i can't say what is that(that is like to explain video) you writing error to 'lymphocyctes'
Say mak ro phage say dendritic cell
Another way to activate white blood cells is cold water 🚿
As a 9 year old I was injected with the white blood cells of a shark... Wonder what affects it had...
This explanation wasn't very good