Would you have your genome sequenced? | Dr Saskia Sanderson | TEDxGoodenoughCollege

Поділитися
Вставка
  • Опубліковано 27 гру 2024

КОМЕНТАРІ • 40

  • @jameszcurtis
    @jameszcurtis 5 років тому +27

    What I would actually be worried about is if a health insurance company could hike your fees up or deny you health insurance for something found that is only a potential to develop a health issue not guaranteed

    • @captainfalcon7227
      @captainfalcon7227 5 років тому +6

      J Curtis we should create discrimination laws against that. With steep penalties for companies using 3rd parties to retrieve genomic information.

    • @SuperKenyasfinest
      @SuperKenyasfinest Рік тому +1

      I was watching a documentary and those laws are in place except for private insurance.

  • @nancymueller6206
    @nancymueller6206 4 роки тому +13

    My daughter and I have undiagnosed symptoms. A complete genome sequencing may, finally, let us know what is causing these symptoms. Of course, we would like tailored treatments, too. Being disabled has pushed us to research.

    • @southernreign1
      @southernreign1 3 роки тому

      Did you ever do it?

    • @erikhoel6081
      @erikhoel6081 2 роки тому

      Yeah, did you ever do it? Its pretty cheap nowadays

    • @nancymueller6206
      @nancymueller6206 2 роки тому

      @@erikhoel6081, we haven’t gotten a genome sequencing done. It cost me $275.00 to find out which painkiller works best with my genes.
      How much would a complete genome sequencing cost? There is ONE geneticist in our state so having him involved means waiting.
      Tell me how we can get the sequencing done and could have it interpreted and could find a medical doctor who would figure out treatment. I can start selling everything we can do without now and raise the money!!

  • @loganwesemann8212
    @loganwesemann8212 Рік тому

    Dr. Sanderson brought up an important point about the ethical issues that get brought up with the increasing use of genome sequencing, such as is it ethically okay to let many people sequence their own genomes, knowing they may not react well to it? How can we know the patient is educated enough in order to properly respond to their sequence results? I mention this because a patient may interpret positive findings to mean they definitely will have a disease, an example being having a gene marker for some cancers or other diseases. Although they have the gene marker, it doesn’t necessarily mean they have the disease, but patients may not interpret that way. One medical principle that comes to mind, however, is the right to know. I do believe that if a patient desires to know, we should be willing to provide the patient the information they need. Another topic that comes to mind is incidental findings. A patient may get a sequence looking for certain markers in their genetics, but find something totally different. I believe medical professionals should be trained and have open discussing regarding incidental findings so the person knows all the possibilities of performing the genetic sequencing. Overall, this talk was excellent and I’m grateful for the topics that were brought up.

  • @MedschoolMom
    @MedschoolMom Рік тому

    I want to thank Dr. Sanderson for sharing the story of her mother. I also hope genetic testing can lead to advances in mental health treatments. I agree with Dr. Sanderson’s prediction that soon everyone will have the opportunity to have their genome sequenced. That does raise some ethical concerns. In these early stages as we’re still just starting to understand genetic sequencing, are we sometimes doing more harm than good? As Dr Sanderson discussed from her research, knowing about risk factors often doesn’t do much for patients beyond adding to their stress and anxiety. Sometimes the results of the sequencing might push patients to undergo expensive and frequently unnecessary tests and procedures. Often the only things people can really do to prevent some of these diseases they’re predisposed to include having a healthy diet and exercising - things we should be doing anyway. In many ways it seems getting your genome sequenced might not help, and could hurt. Before pushing your patients to get their genome sequenced, or before telling them the results of the sequencing, it’s our duty as physicians to consider if we’re actually causing more harm than good.

  • @RochaHolmes
    @RochaHolmes 5 років тому +7

    Another use for whole genome sequencing (WGS) is for genetic genealogy. That was never mentioned because the focus of the talk was on health. But genealogy is a very big interest in so many. It's even my occupation and I can tell you we are getting amazing results when you apply the WGS results for genealogy and discovering ancestral connections around the world. See my own video about how this works.

  • @erikhoel6081
    @erikhoel6081 2 роки тому +2

    2022 - tens of millions have had their genome tested

  • @curllymocha3580
    @curllymocha3580 10 днів тому

    It helps you feel empowered if you have a lot of symptoms and a lot of medical adversity with no answers/diagnoses.

  • @NikhilMandrekar
    @NikhilMandrekar 4 роки тому +12

    Please improve the audio on this video.

    • @MegaHELLRAISER01
      @MegaHELLRAISER01 4 роки тому +1

      Literally just increase the volume

    • @cedarwine
      @cedarwine 4 роки тому +2

      @@MegaHELLRAISER01 doesn't fix it

  • @mcintosh2001
    @mcintosh2001 5 років тому +4

    Interesting talk - the mental health angle is very interesting but usually under-explored

  • @mirriamchishachimba5212
    @mirriamchishachimba5212 4 роки тому +2

    This is great, I would definitely go for it

  • @amyn7501
    @amyn7501 7 місяців тому

    I've been wanting to do this for years. My issue is finding a good online place to do it. My Dr. has no clue about this. My family has died from cryptogentnic Liver disease with no answers. I just want some answers.

  • @МаксимК-в2л
    @МаксимК-в2л 6 років тому +3

    Very useful. thanks!

  • @naiitabolsen819
    @naiitabolsen819 5 років тому +2

    where can i do it?

    • @_Moto215
      @_Moto215 4 роки тому

      Veritas Genetics. About $599 right now.

  • @JewelHudiyel
    @JewelHudiyel 3 місяці тому

    Blocked genome sequencing

  • @riverbender9898
    @riverbender9898 5 років тому +22

    Great content. Barely audible.

    • @MegaHELLRAISER01
      @MegaHELLRAISER01 4 роки тому +4

      Turn up the volume then

    • @riverbender9898
      @riverbender9898 4 роки тому +2

      I did, genius

    • @MegaHELLRAISER01
      @MegaHELLRAISER01 4 роки тому

      riverbender Your previous comment says otherwise

    • @riverbender9898
      @riverbender9898 4 роки тому +2

      With the volume at maximum, many words remained inaudible to me.

    • @doittoday1
      @doittoday1 4 роки тому

      riverbender I had the same issue, 100% volume and hardly audible.

  • @jerrynoury4386
    @jerrynoury4386 10 місяців тому

    PLEASE DO FATHER / SON LAW SUIT CASES ( BURDEN OF PROOF CANCER)..FROM NEBUA TESTING...

  • @enriquellerena4779
    @enriquellerena4779 3 роки тому +1

    Im not scared about death... so il do it

  • @billysmith3399
    @billysmith3399 5 років тому +1

    awesome

  • @JewelHudiyel
    @JewelHudiyel 3 місяці тому

    Our body is hard to sequenced you are trespassing !!!

  • @MedicalEthics-f7l
    @MedicalEthics-f7l Рік тому +1

    I believe Dr. Sanderson failed to address one of the most critical aspects of genome sequencing, which is the proper interpretation of genomic data by physicians. Genome sequencing has the potential to revolutionize medicine; however, the results are not always straightforward. The complexity of genetic data requires a high level of expertise in interpretation, and a misinterpretation of the results could lead to unnecessary testing, overdiagnosis, overtreatment, and unnecessary anxiety of the patient. Accurate interpretation of a patient's genomic data is also critical in managing their mental health. Genome sequencing can provide information regarding an individual's risk for numerous diseases, including those for which there is no cure, such as Alzheimer's disease. Receiving this information could cause significant distress and anxiety for the patient and their family members, leading to mental health issues such as depression, anxiety, and post-traumatic stress disorder. Dr. Sanderson argues this was not the case in the research she conducted, however, the study only had 35 generally healthy participants. How would this compare to patients who are not generally healthy, but have comorbidities, especially those already suffering from anxiety or depression? Additionally, Dr. Sanderson conducted this study and delivered the results utilizing a "genomic sequencing team" that included psychologists, bioinformaticians, computational biologists, clinical geneticists, and genetic counselors. This is an impressive list of experts on this topic, who would have the knowledge and ability to accurately interpret and communicate their participant's genomic data, as well as address questions and concerns from the participant. While this certainly lends credibility to their research, it may be the reason for the participants' responses to their genomic data. However, it is unlikely that the general population will receive this same level of expertise in the interpretation and discussion of their genomic data, making it difficult to extrapolate the data from this research. Therefore, healthcare professionals must be adequately trained to interpret genetic data accurately and communicate the results effectively to patients. It should be done in a way that considers the patients' emotional and psychological needs, such as providing emotional support, counseling, and clear and concise explanations of the results. Furthermore, genetic counseling services should be made available to individuals who undergo genome sequencing. This can help patients understand the potential implications of their genomic data, as well as the possible risks, benefits, and limitations of genome sequencing. Genetic counselors can also provide emotional support and help patients make informed decisions about their health and medical care. Genome sequencing is undoubtedly beneficial in providing personalized care to patients and even has the potential to empower patients in preventing some diseases. However, the interpretation of genetic data must be done accurately, and the results should be communicated effectively to patients to prevent unnecessary interventions and mental health issues.

  • @JewelHudiyel
    @JewelHudiyel 3 місяці тому

    You have created problema

  • @irishman9877
    @irishman9877 3 роки тому

    Killing more like 💉