Imaging brain tumors - 3 - Oligodendrogliomas
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- Опубліковано 2 жов 2024
- Brain tumors are one of the most common diagnoses addressed in neuroradiology. This covers a wide spectrum of disease, from primary brain tumors like gliomas and glioblastomas to secondary disease like metastases. This lecture covers the spectrum of the most common brain tumors, with an emphasis on primary brain tumors.
This video discusses imaging and genetic features of oligodendrogliomas, including low grade oligodendrogliomas (WHO grade 2) and anaplastic oligodendroglioma (grade 3). By definition, these tumors have 1p19q codeletion and IDH mutation. Oligodendrogliomas have better survival than astrocytomas. Higher grade tumors are more likely to have more mass effect, more enhancement, and less well-defined margins. However, oligodendrogliomas typically do not degenerate into glioblastomas.
Additional videos in the playlist will address the imaging findings of other types of brain tumors.
The level of this lecture is appropriate for radiology residents, radiology fellows, and trainees in other specialties who have an interest in neuroradiology or may see patients with brain tumors.
Check out this video and additional content on www.learnneuror...
since voice quality improves significantly, maybe it is a good idea to record these great lectures again to make it better.
Yeah, I agree, and I'll go back and do some of the earlier lectures when I have a chance to update them with new and better images and audio.
Excellent teacher.
Just had a gross total resection on what the nuerologist believed to be a grade 3 Anaplastic oligodendroglioma. Awaiting pathology results. In week three of recovery. If I'm understanding this video correctly I have a really good chance at not getting any reoccurring tumors. The surgeon was able to remove it with good margins and I'm hoping for some good news on my follow up!
I'm sorry to hear you had a tumor and I'm glad you are recovering. These are challenging tumors so I'm glad your surgery went well and the surgeon was able to remove most of the tumor. They will probably recommend some additional therapy (chemotherapy/radiation) after you recover, if you haven't talked about it already. With this treatment, there is a good chance you can have many tumor-free years, but it's important to talk to your doctor about the specific tumor because there are other things that can affect the possible outcomes.
Good luck with the treatment!
@@LearnNeuroradiology thanks just awaiting my pathology results. Spot on with everything my nuerosurgeon told me. The recovery is the hardest part. From super active to inactive for several weeks is tough on the psyche
@@justinhunstad1760 hello! I recently was diagnosed with the same tumor on my right frontal lobe, in week 4 of recovery now. I completely understand how it messes up your psyche from being super active to not so much anymore. Just curious of how you’re doing now?! Best of luck to you! Thanks for sharing!! You are not alone!! 🙏
@@pakventurez I'm sorry to hear you are facing the same challenges. I'm doing okay. I've recovered rather well. Back at work. The biggest dislike for me is the seizure medication. It's got some tough side effects. Advice I could give us just stay the course and don't stress about things you can't control. Learn to let go of your future plans and start to accept the reality of your new life. Take time to cry if you feel upset and don't be too proud to lean on your supports when you need to.
hello! how are you now ?
My cousin has been diagnosed with OLIG2 today with iDh mutant and ATrX retained is it completely treatable and removable doctors saying in early stages and have not progressed yet does this benign or malignant
It's a malignant tumor, but sometimes can be cured, or at least unchanged, for a long time. You'll have to ask the doctors for more specific information
Always get the disk to take with you and learn to read mri
Good suggestion, that way if you change doctors you can also take it with you.
Luckily things are a lot better now and we can often share images electronically too.
I have recently had a grade 2 oligodendroglioma completely removed (6 weeks ago to be exact) I feel very fortunate that the surgeon could remove it including healthy surrounding tissue. do you believe this may improve my chances of reoccurrence? Thanks
I'm sorry to hear that you had an oligodendroglioma. Yes, more complete resections are associated with slower recurrence and better outcomes in general. Good luck and good health!
How are you this time please tell
@@Saimaalikharadi i am doing well thanks, scans are every 3 months and so far so good with them. Hopefully i do not ever have a reoccurrence!
@@patrick9379 no you will not
@@patrick9379 after surgery doctor give you radiation and chemo pills
Does cystic degeneration and calcification occur as an oligodendroglioma starts growing larger?
I don't think these processes are completely understood. Small tumors can have either. Calcification undoubtedly takes some time to develop, but cysts can often be present as well.
Makes sense but my assumption is in a small lesion (say under 1cm), the likelihood of these changes occurring is very small correct? And if present they would form a minor portion of the tumor body which would otherwise be homogenously T2/FLAIR hyperintense?
Good lecture but ur voice is too slow
Noted. If you want to speed it up, why don't you try the youtube controls to play it faster. It might suit you better at 1.25 or 1.5 speed.
Sound of this video has some vibration that makes listening very almost painful. Not present while I listen other videos.
Sorry to hear. Hopefully the new videos are better
Me tocó una cirugía de estás hace unos días! Si alguien necesita una palabra de aliento o simplemente hablar! Me mandan por privado!
Good luck!
Pul Monic hola! Muy bien por suerte! De hecho ya he vuelto a trabajar, entrenar y correr.
Bad voice sorry
Thank you
You're welcome
My gf had grade 2 glioma which was in progressive stage.. Treated with SRS.. Removed it completely.. Still facing some minor difficulties in daily life.. Will she be able to lead a normal life hereafter?
I'm sorry to hear. It's hard to predict how normal the future will be for her because there is a wide range of deficits she might have. However, many people live with these tumors and have full lives. If she's lucky enough to have all the tumor removed and get SRS, she can do very well. Good luck!
It's hard to get back to normal almost impossible it's true and tragic too😟
Hello
Iam 27 year old
Recently iam diagnosed with oligandroglioma grade 3 (1p19q)(right temporal lobe)
My surgery completed successfully (Alhamdulillah)
My surgeon said he can remove all the tumor, if there left microscopic cells something that we can’t see with eyes for that they are going to give me 6 week radiation with chemo pills
Sir it can be cured or not?
Salam Afiya, I had the same tumour and had 33 session of radio & 6 cycle of chemo. May Allah give you good health. How's ur radio therapy going?
@@maliksuper919now you ok
@@maliksuper919how are you now
Voice is not clear .
His voice is very clear, you just clearly cannot understand the language
@@Bloodfang152 , but, he should have spoken loudly
My father was recently diagnosed (7 days ago) with this tumor on his frontal left lobe. He had surgery yesterday, but they were only able to remove 50%. Because of Covid, it has been very difficult communicating with the doctors, considering that we’re not allowed in the hospital. Is there any info you can provide that will help understand what happens with the other 50% if the tumor. Thank you!
I'm sorry to hear your father has a tumor.
Sometimes you can't remove all of a tumor because it is unsafe to remove it all or would cause too many side effects. For most tumors, you'll treat the rest with chemotherapy and radiation afterwards.
For some lower grade tumors, they might just want to follow up the remaining tumor with imaging and wait until it gets worse to give radiation. The good news is, most of the time these decisions are made at your first follow-up appointment, so hopefully even with covid someone from your family can go with him.
@@unclejunior2668 I'm sorry about your dad. You're right, these are terrible tumors in general, but GBM especially. A lot of our research is in ways to try to do better so that people can live longer more meaningful lives after treatment.
Oligodendrogliomas are the best of a bad bunch. They have the best survival, respond the best to treatment, and never turn into GBMs (although the anaplastic oligodendrogliomas can be pretty bad). Still not great, but better.
My dream for everyone is that one day brain tumor treatment will be a cure, but right now it's not there, so we keep trying!
My mother also had oligo3 right frontal lobe. She did her surgery feb,2020. 90% removed then she take radiation and chemo.
Hows your dad now?
My mother was diagnosed with astrocytroma,grade3 , idh1 mutant 4 month ago on her left frontal ... now she is looking fine but doctors suggested me for radiation/ chemo but I am scared whether its safe or not as she is looking fine for now and is it curable as she is absolutely fine after operation and having astrocytroma grade3, idh1 mutant
@@Urvashi618 my father had done several rounds of radiation at this point and it takes a toll on his body, he gets very sick during these treatments. I hope your mom recovers from this, best wishes💜
Excellent but voice in not good 😐 😕
Voice is not clear 😔
your case is good but please speak in your real voice, it so irritating
Yeah yeah the later videos have better audio
I have grade 2 oligodendro glioma :(
I'm sorry to hear that. A brain tumor diagnosis is something I wish no one had to hear, and we're doing our best to improve the treatments available.
The good news is, grade 2 oligodendrogliomas are among the slowest growing and most treatable brain tumors. So there is a good chance you can have a good life after treatment. I wish you the best of luck with your treatments.
@@LearnNeuroradiology thanks to your saggesstion next what i will do sir plz give your con number
How are you this time please tell