How Do Moles Become Cancerous?
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- Опубліковано 29 лип 2019
- Most people have multiple moles, and they come in lots of different shapes and sizes, but when is a mole just a mole, and how does it turn into a deadly form of cancer?
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Moles, birthmarks, beauty marks. Usually they’re harmless, but occasionally they could be a sign of a very serious disease: melanoma. Not all melanomas start from a mole, but all moles are made up of the type of cells that can become melanomas: melanocytes.
The melanocytes deliver melanin to the surrounding keratinocytes, or skin cells in the epidermis, giving our skin its color. So when we come in contact with UV light from the Sun, this melanin protects our skin from damage, while also signaling to the body to produce more melanin.
This system works pretty well, but it’s not perfect.
Learn more about melanoma, mutations (like the BRAF mutation), immunotherapy, and more in this episode of SICK.
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SICK is a new series that looks at how diseases actually work inside our body. We'll be visiting medical centers and talking to top researchers and doctors to uncover the mysteries of viruses, bacteria, fungi and our own immune system. Come back every Tuesday for a new episode and let us know in the comments which diseases you think we should cover next.
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Read More:
The Protective Role of Melanin Against UV Damage in Human Skin
www.ncbi.nlm.nih.gov/pmc/arti...
Skin melanocytes: biology and development
www.ncbi.nlm.nih.gov/pmc/arti...
Skin 'sees' UV light, starts producing pigment
www.sciencedaily.com/releases...
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Hi, thanks for watching! Is there a particular disease you're curious about? Let us know in the comments what you'd like us to cover next!
Please cover Lupus.
POTS EDS MCAS CFS and the link recently found between them please!
Tuberculosis
@@bmblbeee3920 YES
Ringworm
That poor guy is speaking like he's being held at gunpoint
Omg! I was thinking the _same exact thing_ ! Like some one said, "if you move we will kill you!"
True lol
He's talking about the scary topic of cancer which pretty much holds you at gunpoint until it decides it's done with you
plz blink boi
E'Osiris 🤦♂️
This made me very self-conscious about my moles lmao
Blah Bleh wrf wrong with you
Blah Bleh lol i love youtube
MOLAY MOLAY MOLAY MOLAY MOLAY
One important thing my doctor once told me is that if a mole has hair growing out of it it's highly unlikely to be cancerous, since that would mess with the follicles. Good to know.
Omg thank you. Such a relief
I have a mole with a hair on it, and I'm pretty sure it wasn't this big a few years ago. It didn't really grow that much though, but it's definitely growing.
I have one with hair, it seriously made me super concious. But knowing this, kinda made me reliefed
@@alamrasyidi4097 Take a picture of it every few weeks
Alam Rasyidi evolution is a very important sign. Any growth of a mole should be a definite call to the dermatologist. Always better safe than sorry
Today's fact: The collars on men's dress shirts used to be detachable. This was to save on laundry costs as the collar was the part that needed cleaning the most frequently.
Just wash your neck every morning🤔
The moles got it first!!!
What does the defects of clothes have to do with a video about moles and melanoma
@@michealbmillzlynnmass4928 first time here?
that's pretty cool info actually, thanks! lol I've seen your factorinos on other vids, it's hilarious
this comment section needs to chill!
Maybe he isn't used to being interviewed, maybe this was his first interview...
good thing that he atleast tried.
As an introvert, only people like me understand more than anyone else.
this is like a bad audition tape
I went from introverted to being a bit of both, extroverted and introverted and the truth is that it's hard but ultimately it's better to be balanced
Idk I thought he did a really good job lol
You chill!
I once knew someone who had 6.02 X 10^23 moles on his body.
It was a mole of moles.
:D
That guy must be Avogadro
@@hazelmaeantimor4613 lol
We got chemistry jokes y'all.
6.62607004
It's extremely rare that a melanoma develops from an already existing mole. Most of the time they grow from nothing.
That's true. Melanomas can look like little brown smudges which makes it hard to notice yourself
Perhaps let's say it the other way round: Melanomes can hide amongst those moles. It's not easy to find a melanome when you have many moles.
Excuse me - I"ll ABCDE all over my body now.
Rip
Cool
Rip in advance. I pray for your peaceful afterlife in heaven. 😭
@@wizard6684 heaven?
How are you now?
I have about 37 moles just from my neck and up
Now I'm Hella self conscious about it 💀
bruh i have 20-30 birthmark moles on my legs and i think its completely normal.
Was that dude actually just a random guy reading off a script ¿
Yeah, I know him. He's a huge stoner, we used to hang out playing Super Smash Bros for like 16 hours a day. He got sucked into 4chan and that was the last I really saw of him.
Or just a nervous guy that rehearsed and prepared his responses.
Clorox Bleach he’s an MD researcher. This is really common in science. They’re really bad at talking and communicating with other people. Source: am biologist
@@TheSouthwestBoyz But why is that? It's an interesting phenomenon. My man-who-failed-biology theory is maybe the brain adapts to all the information they absorb by utilising other areas for storing that knowledge at the cost of social skills. I know I'm wrong but hopefully you can give us a more accurate answer?
@@10aDowningStreetEverything is a skill that needs practice. Some skills have less practice then more. He might have not done a lot of practice speaking from a script or in front of a camera.
He got a lot more comfortable as the interview went on :)
After watching this video... I have a request.
Seeker, can you do a video explaining WHY we have moles?
00:54 .... Pay attenion this time lol
Thinking like a real scientist! Not in hunger for the answer, but for the next question! :D
is it me or the guys seemed more passionate about his music allegory than the entirety of his explanation?
Brb, gonna call my dermatologist
Always wondered how it happened. Great video. Thanks.
I became very aware of sun exposure after my mom was diagnosed with melanoma earlier this year. Please use sunscreen and upf clothing! And stay in the shade when you can!
How is she now?
@@Taptapfail Thankfully, she had a subtype that mostly grew horizontally and not down so it was still fairly early stage when removed. She should be fine, with the addition of a new large scar. Very lucky!
@@Roll587 Nice news. Thanks for sharing :D
Interesting medical topic you presented!!
now i'm scared.
don’t be 🤣. it’s very rare for your mole to be cancerous. if you’re scared simply go to dermatologist and get it removed! don’t be worried okay guys? you’ll be fine. 💯
That piano analogy was great. Loved it.
Awesome video btw.
How you can spot melanoma
-Wounds that don’t heal
-Redness, swelling or tender skin
-Oozing or bleeding from a mole
-Dark spots in the eyes, loss of sight or blurry vision
I have all of these but my wounds heal so im fine, i think
I once fell off from my bike and got a wound . It had never bleeded since then , although I have a blurry vision
So do you think I have melonoma ?
death
Sayonara if you have a mole that bleeds you should get it checked
I have a wound that won't heal, started 3 months ago! Getting it checked out this week. If i don't comment later, i might of expired ~ 🤧☠️😇
I did a presentation of melanoma at school! And I wish you made this like a year and a half ago, it would’ve been really good for it. It supports a lot of what I found
The type of video which you want to watch and not, at the same time.
Mob_Abominator so true :/
i was really debating clicking on this video and now i understand why :)
Immune cell will ask the other cells
"How abnormal are you?"
Me: My everyday life.
😂😂😂
Hey Seeker, could you please do a video on IBS ?
When I was about 3 yrsd(female) I used to have a mole on my inner thigh that had started about the size of a dime but it grew very quickly and developed this sort of clear halo around it, and basically checked off all the ABCDE rules. When we went back to the doctor they had told my parents that I had a condition that they called "spitz nevus" or "juvenile melanoma" at the time, and needed to be removed because it had "malignant potential". I went into surgery and they were able to take it out fine but I've still got some decent sized stiches in my thigh now due to the skin growing over and around it. My doctors have always said it was crazy rare that it happened to me so young. But it's always cool for me to see videos like this that dive into a bit of what had happened.
I thought the dude did a really good job presenting??? I didn’t really watch the video but listening to it was very easy to understand.
If I have calculated myself correctly, I have around 40 or more moles on my body :) but out of those moles only two of them are raised (which I've had since my childhood), and the rest are really small and flat.
I wanna get rid of my beauty marks because they dont rly make me feel beautiful 😭
I was born with mine and they haven't changed in the almost 20 years I've been alive.
Nice animations.
Sounds like this is his first time on camera.
Hi seeker
Interesting tolic
Learned a new lesson..
Sick videos are awesome to watch..
Thanks for the video..🙏👍😊
Now I'm scared of all the spots on me
I just realized that accessibility and rewards are what makes someone achieve success aside from innate ability.
I've always had a paranoia of too much sun light since I was a child.
As a Mole myself, I find this content to be exceedingly prejudiced towards my kind and implore everyone to cancel this expert. I am not toxic nor cancerous I just wish to engage in responsible subterranean behaviors.
Yeah, that whole primary prevention thing is great and all but I’m so terrible with it
my mother-in-law had these huge moles on her chest and she was always complaining about them hurting and she had the worst back pain. she was going back n fourth to the ER about the back pain, they just kept giving her stronger and stronger pain meds until she finally had to fall off work and stay home because the discomfort wouldn't allow her to sit at work..... literally 2 weeks after she decided to leave work, she was diagnosed with myeloma. do moles foresee other types of cancers too ? i am covered in moles, head to toe. only a few are raised/stick out. my grandma and mom has lots of them too... i've never worried about them being cancerous. my oldest son has a huge one on his arm that i worry about.
Be imunne, be happy
For one who focuses is studies on the epithelial tissue he's pretty dead inside
just had another precancerous mole removed - please get checked everyone!
*video talks about skin cancer
Me: *Laughs in brown skin*
@@user-kj8hg This stands against all my belief and understanding of skin cancer. Guess it's time to do some googling
Melanin in the skin protects you from skin cancer developing as a result of Ultraviolet radiation but doesn't reduce the chance of a naevus (mole) becoming cancerous.
@@TheNuvish idk if that's true, but I'll take your word on it
@@user-kj8hg yes, but the way that works is we're less likely to actually get skin cancer, but if we do, it's much harder to diagnose. And by the time it's found, it's usually too late
Do not hate brothers and sisters of the comment section. Thou not bestow anger. U are just going thru.a tuff time. Reach out to a neighbor or a friend if in need of a hug. If thou must shed a tear I offer you tissues and an open ear
I have moles... oof not many tho
Chicken Ramen poor
Most of mine are on my back, I have very little idea what they look like
Austin powers : molemolemolemole
bruh, the science guy got the same glasses as i do
Please make video on how close are we to build iron-man arc reactor
Nice thumbnail name
Seeker
Sick XD i mean it
I have about 50 moles on my right arm and my left arm, also 50 on both legs and some on my back and on my face the risk of cancer is great.
Same
what about freckles? seems like a similar thing. I have hundreds of them. Also, moles I get are pink. why are gingers so weird?
Our bodies are beautiful
00:11 a mole in the form of Belgium, aka my land
The voice💓💓💓💓
I've always been praised for my perfect complexion, even in highschool I didn't get zits, and if I did it'd be one big one that'd be gone in a day or two. Otherwise, not a single freckle on me. Other than one big, fat mole on my back above my ass. Things so huge, it's the size of a quarter. Its like my entire body put every blemish into that one spot. People would see me at the beach and say "hey bro did you shit your pants?" No, it's a giant mole that's permanently fused to my otherwise perfect body. I'm not so upset about it though, I'm blessed for what I got as it is.
So are u saying that I have cancer ??
Holy moly....
Never click on video this quick 😂😂😂
I am concerned
Sometimes I discover a new mole on my body that I’ve never seen before
Same. And now that I'm googling my symptoms every other day, I've become a hypochondriac mess.
New moles can appear in your teenage years and 20's, even 30's... it's normal
I don't really go into the sun very often cuz I'm so light skinned I burn easily.
I thought I just had freckles all over my body
You might. Freckles are moles can look similar.
i had 5 moles on the right side of my face and 0 on my left and i got them all removed
Share this video please, you could save a life...
5:21 "-and we do have that pill, that pill is called winning the genetic lottery..."
Oh, well if that's all...
The crack on my screen looked like a Hairy mole. Through me off.. haha
I thought that was a teddy bear in the thumbnail. 😂
2012iwanttogohome at first I was like how and then I was like Stephen A. Smith
My son has a big birthmark on his back. Irregular and raised in shape. Don't know if it could be dangerous.
Well it’s hard to get too much sun exposure in the uk so I think I’m good.
What about green /blue moles. Anyone know anything about those? I had one in my back since I can remember, it never causes any pain so I forget I have it sometimes.
Maybe have them checked? I’ve never heard of moles that color.
What about Malls ?
If a mole relates to any of the ABCDE categories, does it automatically mean it’s cancerous?
He reminds me of this one science project I did a while back, where I made a clone that was half David Byrne and half Rick Moranis. I was going for Byrne's musical ability and Moranis' endearing awkwardness, but what I got was something with the musical ability of Moranis (almost completely nonfunctional, musically speaking), the wild need for experimentalism of Byrne, and something that was somehow 105% awkward. For some reason, it looked exactly like Hugh Grant.
I was scared to watch this video as I have those on my face and I dislike them. Would look so much better without and it is destroying my confidence... can you make a video if they are removable?
They are, but to do so will leave a scar.
God, will check my moles now.
That pill would be hype because it would make people feel like they can continue all their bad habits consequence free. Having to actually commit to a healthy lifestyle is definitely not the same thing.
It's Stuart from TBBT
"The only pill we offer is a healthy lifestyle." lmao
That like talking about being high on life
That is the kind of thing that needs to be taught at school.
School is made to teach you how to learn and not teach you anything useful.
Why not do both ?
I’m scared 😪
Ahh nice i got a shot tone
it's simple.
by playing fortnite.
My mole just grew in size ..... 😶 Just noticed now 🤐
Holy moly
R/Whoosh
@@FBISHOJI it's r/woooosh and btw it was a pun
Did someone tell A-aron they'd kill him if he moved?
When they destroy your backyard.
oh wow im going to die now
I dont have any moles !!
i have a mole and its black💀
I read the title as "How do males become cancerous?"
tbh i hate moles in general
Really only 10 seconds that gets cut off for the most important part of the video how to not get cancer?
Why is the audio is playing at 1.5x speed?
Is the dude a human or robot?
I have a mole on the inside of my toe, guess I could just cut it off if it turns cancerous. :)
Nolan Shaw well if you do it that way there’s still a chance some of it spread through blood
@@osslayer8976 just gonna cut my toe right off
I have one on my heel
Goddammit,Avogadro.
Nani
Lol i thought the title said "How do memes become cancerous?"