Peptide Bond Formation | Animation

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During protein synthesis, peptide bonds link amino acids together in the order specified by DNA instructions. In this case, the first two amino acids in the protein are methionine and alanine. Here are ball and stick models of these amino acids. Peptide bonds formation is a type of condensation reaction. During the reaction, the highlighted atoms are removed. The carbon atom in the carboxyl group of the methionine becomes link to the nitrogen atom in the amino group of alanine. A peptide bonds forms between methionine and alanine. Water forms as a by product of the reaction. The next amino acid specified by the DNA is leucine. Again, atoms are removed and a new covalent bond forms. Another molecule of water forms as a byproduct. The next amino acid is tryptophan. Another peptide bonds forms and another molecule of water is released. Noticed that the backbone of a forming polypeptide consists of carbon atoms with nitrogen atoms at regular intervals. The sequence of amino acids in a polypeptide chain is the primary structure of a protein. It is the primary structure that gives rise to a protein's unique properties.

[@austintbk6027]

WOW, clear and precise... you've saved me a ton amount of time and stress...Sir , you are amazing. Thank you :)

[@tom230895]

It has been a while since I've come across such an informative and clear video with no visual clutter so I really appreciated this one, Thanks a lot 👍

[@parsley5562]

Thanks for this video! Super clear and helpful to see an animated diagram while you explain.

[@Wowo89101]

Thank you so much for this video!! so helpful

[@nicoledeji3999]

very nice. I like the way you explained it.

[@sotelov-f8m]

Thank you!

[@georgemthenga3144]

Thanks to you

[@nalgenius6955]

Great video, though the oxygen on leucine should not be in the ball-and-stick backbone at 1:04

[@ManSingh-qd1bq]

Nice

[@tommycoleman4513]

Great animation, thank you! With respect, I believe the nitrogen in the Trp structure should not be in the double bond.

[@StudyForceOnline]

Hi Tommy, could you reference the timeframe for this observation? I couldn't find what you were saying...

[@tommytucker1820]

@@StudyForceOnline Yes Sir, the correct tryptophan structure is seen at 1:00 but at 1:05, when it is incorporated in the polypeptide, the hex-ring is shifted and places the indole nitrogen in a double bond.

[@natedoggraymond]

Great video! Really! Thank you!
As a matter of constructive criticism: the peptide bond between Leu and Trp seems to include an oxygen in the backbone, isn't this incorrect?

[@safaa1515]

Thank you..
Peptide bonds have parietal double bond character due to resonance ..
I just wonder what is resonance?
And thanks

[@AyomideAmudipe]

What will be the name of the 4 Amino acid

[@ahmadkeshk1743]

Wrong peptide bond only one Hydrogen atom from amino group not 2 hydrogen atoms

[@StudyForceOnline]

What is the timeframe?

[@Sadashivjwellers]

Kya aap gaon se h 😂