Thank you, Dr. Griggs, for the comprehensive video on this important topic. I got some new and very useful information for my further course of action - I had genetic testing in October last year and was found to have the Check 2 mutation.
Hi Dr. Thank you for your explaination i want to know more about triple negative cancer that your mention that its more common in women carrying the brca 1 & 2 mutations. Its this type of cancer aggressive? Thank you
Thank you for this very informative video. I am a stage 3a triple negative breast cancer warrior. I just finished all my treatments 3 months ago - MRM on my left breast. My Onco has been advising me to take a BRCA test, but I still wasn't able to as I live in a country where the test is only available in our country's Capital City and I live 600 miles away. How soon should I get the test? I may be able to take it come May when I have enough budget.
It’s great that your oncologist is advising you to get the BRCA test-it can provide important information about your future risks and guide your treatment or prevention plan. While sooner is better, May is still reasonable. If you need time to arrange logistics and budget, keep your oncologist informed, and ask if any other supportive steps should be taken in the meantime. It may also be helpful to know that the companies that do the testing have patient assistance programs to help with the US$200 to $US400 cost.
If you have either breast cancer characteristics that make testing indicated (triple negative breast cancer) or a compelling personal or family history, testing can be done through your surgeon's office or your oncologist's office. A compelling personal or family history includes cancer in both breasts in you or a family member, ovarian cancer in you or a family member, prostate cancer in you or a family member, and other cancers. Knowing as much information about your family history and sharing that with your medical providers is important. There are other genetic conditions besides BRCA that a family history can reveal.
@@yerbba I was diagnosed breast cancer and undergo mastectomy and series of treatment like chemotherapy.Suddenly in this recent days I notice lump in my lympnodes. What could be the cause of this lump?
Great question! Yes, BRCA carriers have different treatment options. Specifically, PARP inhibitors like olaparib are effective in targeting BRCA-mutated tumors and do not work in others. In addition, platinum-based chemotherapy may also work well. Additionally, knowing about a BRCA mutation can influence surgical decisions, such as opting for a bilateral mastectomy to reduce risk of cancer in the other breast and removal of the ovaries.
I was diagnosed with lobular breast cancer 9 years old and ovarian cancer and breast cancer recurrence recently. Finally they told me I have gene mutation RAD51-C. 😢. Do you know any characters of RAD51-C? What's the survival rate? Thanks 🙏
Thanks for writing. You are going through a lot. Breast cancers associated with a RAD15-C mutation are more likely to be triple-negative. It does not appear that the prognosis is worse than in other people with triple-negative breast cancer not related to a gene mutation. Wishing you the best as you move forward in your treatment.
Great question! Yes, BRCA carriers have different treatment options. Specifically, PARP inhibitors like olaparib are effective in targeting BRCA-mutated tumors and do not work in others. In addition, platinum-based chemotherapy may also work well. Additionally, knowing about a BRCA mutation can influence surgical decisions, such as opting for a bilateral mastectomy to reduce risk of cancer in the other breast and removal of the ovaries.
How much of a chance would I have with 3 out of the 4 girls in my family have had breast cancer me being the only one that hasn't one passed from it...
If there is a gene in your family that is accounting for the increased risk of breast cancer and if your sisters and you have the same mother and father, each of their children has a 50-50 chance of inheriting the "deleterious" gene (the one that is associated with breast cancer). Each sibling has an indepedent chance; that is, each child has a 50-50 chance. If there is no identified gene, this would be a familial breast cancer. It is difficult to estimate the risk in each child. The risk is higher than in the general population. It would probably be helpful to find out if any of your siblings has had genetic testing in the last 7 years. The tests have changed, and people who were tested a while ago are advised to be retested.
Extremely clear and informative.
We're glad this video was helpful!
Thank you, Dr. Griggs, for your medical information, regarding cancer.
Thank you for watching!
Thank you, Dr. Griggs, for the comprehensive video on this important topic. I got some new and very useful information for my further course of action - I had genetic testing in October last year and was found to have the Check 2 mutation.
Thank you for sharing your experience. So happy the video was helpful.
Thank u so much Dr for providing wonderful information about brca geness….
Loads of ❤ from INDIA…
❤❤❤❤❤
Thank you for watching!
It has been. Most helpful thanks for putting this out there!
😐😐
Thank you for watching and we are so glad you found this video helpful. We appreciate you!
Hi Dr. Thank you for your explaination i want to know more about triple negative cancer that your mention that its more common in women carrying the brca 1 & 2 mutations. Its this type of cancer aggressive? Thank you
In general, triple-negative breast cancer is considered more aggressive. Nonetheless, the chances of cure are good for most people.
Good morning 🌞
Good morning! Thank you for watching.
Thank you for this very informative video. I am a stage 3a triple negative breast cancer warrior. I just finished all my treatments 3 months ago - MRM on my left breast. My Onco has been advising me to take a BRCA test, but I still wasn't able to as I live in a country where the test is only available in our country's Capital City and I live 600 miles away. How soon should I get the test? I may be able to take it come May when I have enough budget.
It’s great that your oncologist is advising you to get the BRCA test-it can provide important information about your future risks and guide your treatment or prevention plan. While sooner is better, May is still reasonable. If you need time to arrange logistics and budget, keep your oncologist informed, and ask if any other supportive steps should be taken in the meantime. It may also be helpful to know that the companies that do the testing have patient assistance programs to help with the US$200 to $US400 cost.
Thank you for the idea about brca mutations doc. Where can I ask the brca test?
If you have either breast cancer characteristics that make testing indicated (triple negative breast cancer) or a compelling personal or family history, testing can be done through your surgeon's office or your oncologist's office. A compelling personal or family history includes cancer in both breasts in you or a family member, ovarian cancer in you or a family member, prostate cancer in you or a family member, and other cancers. Knowing as much information about your family history and sharing that with your medical providers is important. There are other genetic conditions besides BRCA that a family history can reveal.
@@yerbba I was diagnosed breast cancer and undergo mastectomy and series of treatment like chemotherapy.Suddenly in this recent days I notice lump in my lympnodes. What could be the cause of this lump?
How does having the gene affect treatment?
Great question! Yes, BRCA carriers have different treatment options. Specifically, PARP inhibitors like olaparib are effective in targeting BRCA-mutated tumors and do not work in others. In addition, platinum-based chemotherapy may also work well. Additionally, knowing about a BRCA mutation can influence surgical decisions, such as opting for a bilateral mastectomy to reduce risk of cancer in the other breast and removal of the ovaries.
I was diagnosed with lobular breast cancer 9 years old and ovarian cancer and breast cancer recurrence recently. Finally they told me I have gene mutation RAD51-C. 😢. Do you know any characters of RAD51-C? What's the survival rate? Thanks 🙏
Thanks for writing. You are going through a lot. Breast cancers associated with a RAD15-C mutation are more likely to be triple-negative. It does not appear that the prognosis is worse than in other people with triple-negative breast cancer not related to a gene mutation. Wishing you the best as you move forward in your treatment.
How does having the gene affect the treatment of breast cancer?
Great question! Yes, BRCA carriers have different treatment options. Specifically, PARP inhibitors like olaparib are effective in targeting BRCA-mutated tumors and do not work in others. In addition, platinum-based chemotherapy may also work well. Additionally, knowing about a BRCA mutation can influence surgical decisions, such as opting for a bilateral mastectomy to reduce risk of cancer in the other breast and removal of the ovaries.
Er negative pr(11. 20) persentage her2 negative...stage 2a...gread. 3...brca 1 positive...no node involved...but ma'am...my 2 doughter...19 and 13😭pls maam help
How much of a chance would I have with 3 out of the 4 girls in my family have had breast cancer me being the only one that hasn't one passed from it...
If there is a gene in your family that is accounting for the increased risk of breast cancer and if your sisters and you have the same mother and father, each of their children has a 50-50 chance of inheriting the "deleterious" gene (the one that is associated with breast cancer). Each sibling has an indepedent chance; that is, each child has a 50-50 chance.
If there is no identified gene, this would be a familial breast cancer. It is difficult to estimate the risk in each child. The risk is higher than in the general population.
It would probably be helpful to find out if any of your siblings has had genetic testing in the last 7 years. The tests have changed, and people who were tested a while ago are advised to be retested.
❤❤
Thanks for watching!
Can ca125 test show up for breast cancer
In people with advanced/metastatic breast cancer, CA-125 can be elevated, yes.