"Metabolic Therapy in Glioblastoma" - Dr Matthew Phillips

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  • Опубліковано 14 жов 2024
  • This 2023 Brain Tumour Awareness Month webinar "Metabolic Therapy in Glioblastoma" is presented by Dr Matthew Phillips, FRACP, clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand.
    Dr Phillips discusses the idea that most sporadic cancer is a metabolic disorder, followed by a discussion of our current clinical trial in people with glioblastoma multiforme, which involves the most intensive metabolic therapy program, involving fasting and a modified ketogenic diet, that has ever been applied to any advanced cancer.

КОМЕНТАРІ • 33

  • @stephenwilliams2365
    @stephenwilliams2365 Рік тому +5

    Fabulous talk with thanks to Dr Phillips and the Brain Tumour Support for their superb works.
    Dementia is strong in my family and after some research, almost 5 years ago I started an animal based diet utilising OMAD. I quickly realised some fabulous results including a 10% weight loss, systemic inflammation clearance, hay fever cured and a brain fog I didn't know I had disappearing.
    I'm grateful for all the scientist pushing the lifestyle/ nutrition frontiers and best wishes to all the participants through their challenging times.

    • @drmclphillips
      @drmclphillips Рік тому +1

      Thank you Stephen, and massive congratulations on your approach and results! Keep it up, Matt.

  • @kaleidoscopesky8733
    @kaleidoscopesky8733 Рік тому +4

    These trials will change the future of heath care and therapies. Thank you to the participants, my thoughts are with you. Living a Ketogenic lifestyle is restrictve and you are doing this trial at one of the most difficult times in your life. Love hearing about the progress of different Metabolic programmes...sideline cheerleader.

  • @Roberto-cg2gr
    @Roberto-cg2gr 3 місяці тому +4

    Hope there will be a research on prolonged fasting more than 7 days fasting 14 days to 40 days fasting

  • @joe4piet
    @joe4piet 6 місяців тому +11

    I have lungcancer stage 2 Male 81 years, 93 KG. I am ketonic for 6 weeks now an a new scan showed cellgrowth. I want a one-time radiation in van Leeuwenhoek Cancer insitute in Amsterdam. Have no problem with 3 day fasting and measure my GKI daly It stays around 2 to 4 Not looking forward to chemo. Will keep you posted. Loved your prefomance.

    • @JLH63
      @JLH63 3 місяці тому +1

      Havé you read his ´program’ on his web site metabolic neurologist ?

    • @MoveRestEatMeat
      @MoveRestEatMeat 3 місяці тому

      52:51 I’m surprised you haven’t mentioned Andrew Scarborough or Pablo Kelly😮😢😮

    • @drmclphillips
      @drmclphillips 3 місяці тому +1

      @@MoveRestEatMeat Thank you - however, Andrew has an anaplastic astrocytoma, and Pablo a grade 4 astrocytoma (this used to be called IDH mutant GBM). These are both very, very different from IDH wildtype GBM in terms of prognosis. We are only enrolling IDH wildtype GBMs in the trial, ie the ones with the most difficult prognosis. Best, Matt.

    • @MoveRestEatMeat
      @MoveRestEatMeat 3 місяці тому

      Ah so, thank you. My husband had stage 4 GBM and was gone in just 26 months at age 53. His brother died 3 months before him of the same! He only lived 1 year 😢💔😢

    • @drmclphillips
      @drmclphillips 3 місяці тому +2

      @@MoveRestEatMeat Ah, I am very sorry to hear of this. True GBM is the toughest of the brain cancers by a long shot. This is why we chose it - if benefit can be shown with this one, probably it would apply (to some degree) to many other brain cancers. Sincere Regards, Matt.

  • @bitgirl
    @bitgirl Рік тому +1

    Doctor Phillips, with all due respect, you forgot to mention that fats used in occidental diets are mostly from seed oils which are highly inflammatory. I have been doing fasting and ketogenic diet (only consuming coconut oil, olive oil) for 3 years and i cured from chronic bronchitis and bowel syndrome. This has been the best decision in my life , so I completely appreciate doctors like you doing these clinical trials to support the healing of chronic deseases even worse than mine ❤❤❤ thank you very much and regards from Colombia

  • @echonorris8831
    @echonorris8831 9 місяців тому +4

    Great work!
    I have a brain tumor and I am stable when following the Paleolithic Ketogenic Diet protocol created by Paleo Medicina or ICMNI. I have tried many version of the ketogenic diet and this is the only one that works. It’s hard to follow but very effective. Conventional treatment did not work for me. My tumor cam back and I felt like nothing would work.
    They do have some brain tumor cases with stability of the cancer. Some patients only have used the PKD protocol without the standard of care.
    I am so happy metabolic therapy is being used.

  • @Roberto-cg2gr
    @Roberto-cg2gr 3 місяці тому +1

    How can the public around the world can help finance the research? How can every country around the world help finance the trials?

  • @kathydicioccio6094
    @kathydicioccio6094 24 дні тому

    What about the inflammation and glucose spike caused by irradiation of the brain?

  • @craigrik2699
    @craigrik2699 Рік тому +1

    Hi Matt, how about your normal medication, no change in taking them? I've got Papillary Thyroid Carcinoma S2T3aNM0. I've had my second surgery (1 Feb 22 - TT and 23 lymph nodes removed, 10 PTC & 11 Apr 23 - 18 lymph nodes removed, 9 PTC) but want to get in front of this. I've checked out all your work after being introduced to Metabolic Therapy by watching Dr. Thomas Seyfried. I've tried Keto ages ago but never fasting and never successful with my Keto diet. Certainly willing to make the appropriate changes. I'm a male Maori, 60 yo, 175cm at 106kg, living in Perth, WA. My last TG reading was 8, the nuke dr. said it should be below 1, TSH at 0.16 and FT4 at 25. I meet with the nuke and surgeon team next month for my 3 monthly. Starting off with a 3 day fast starting on Tuesday, looking at getting to a 5 day fast every month. Sorry the question about medication, issues, Blood pressure and gout. Thanks again

  • @WilliamWenzel-r8j
    @WilliamWenzel-r8j 6 місяців тому +2

    Dr, Matthew, is there an update on the trial? Has it ended? How do we access the results? Thank you SO much for your work! I'm the mother of a daughter with glioblastoma and am trying to spread the word!

    • @drmclphillips
      @drmclphillips 3 місяці тому +1

      Hello, very sorry to hear of your daughter. Trial is ongoing. Will be ongoing for a while yet I hope. Matt.

  • @kenadams5504
    @kenadams5504 2 місяці тому +2

    How many type 2 diabetics aren't being advised about ketogenics diets !?.... (just 3 months for Remission of symptoms. !! ) .

    • @RedPilled100
      @RedPilled100 22 дні тому

      Glad to hear about these revolutionary awareness on UA-cam/Social Media.A Dietician here from Fiji 🇫🇯. The majority don't know about these dietary/lifestyle approaches and most either don't believe non-mainstream advice/non-standard treatment

  • @Roberto-cg2gr
    @Roberto-cg2gr 3 місяці тому +1

    Any research on reduction of glutamine in low GKI?
    Down regulating glutamine with exercise in fasted state?

    • @enriquegonzalez9358
      @enriquegonzalez9358 2 місяці тому

      I saw a video that said if you drink green tea or take berberine, it will help reduce the intake of glutamine.

  • @audreyboyle52
    @audreyboyle52 Рік тому +1

    What if a patient is thin to start with (bmi 17). Can they still embark and have success on this protocol without losing weight?

    • @drmclphillips
      @drmclphillips Рік тому +2

      Hi Audrey, we have two people with a low BMI in the trial (one 17-18, the other 19-20). Both are following the program fully. I have noticed that people with a very low BMI lose much less weight with the fasts than overweight people, so I would tentatively say "yes" to success following the program, although there will still be a little weight loss. Fortunately it is easy to gain back after the 5-day fasts, even with 1-2 meals a day keto. At the end of the day, if a person has a GBM, we treat that as the priority and use different methods to minimize weight loss should the BMI be

  • @dogphlap6749
    @dogphlap6749 3 місяці тому +1

    Thanks for the video. I've left you a message on your website contact page. Best regards.

  • @Roberto-cg2gr
    @Roberto-cg2gr 3 місяці тому +1

    How about exercise in fasted state?

    • @clivewells1736
      @clivewells1736 3 місяці тому +2

      Best not too, ESPECIALLY if your fat stores are contaminated with trans fats or seed oils as these are hard to metabolize and your body will instead turn to its protein stores in the muscles and organs. The less demands you make on the fasting body that is ketogenically compromised by unhealthy and toxic fats the better.

    • @Roberto-cg2gr
      @Roberto-cg2gr 3 місяці тому

      @@clivewells1736
      Any published research for your comment?

    • @Roberto-cg2gr
      @Roberto-cg2gr 3 місяці тому

      ​@@clivewells1736
      Pubmed exercise down regulate glutamine

  • @iconic1758
    @iconic1758 Місяць тому +1

    Any phyllodes patient here

  • @DoyleQueena-n2f
    @DoyleQueena-n2f 29 днів тому +1

    Thomas James Walker Jessica Thompson Thomas